Best TWAS P=4.99e-08 · Best GWAS P=3.9e-11 conditioned to 0.000188
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.20 | 3.8e-24 | -4.8 | 5.5 | 5.0e-08 | -0.83 | 0.90 | 0.10 | TRUE |
| 2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ST5 | 0.41 | 0.02 | blup | 128 | 0.13 | 2.3e-05 | 3.9 | -5.3 | 1.2e-07 | 0.58 | 0.03 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STK33 | 0.14 | 0.08 | lasso | 6 | 0.10 | 1.0e-09 | -4.8 | 5.2 | 2.6e-07 | -0.66 | 0.90 | 0.10 | FALSE |