Best TWAS P=9.44e-15 · Best GWAS P=4.47e-15 conditioned to 0.00608
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CYP2R1 | 0.06 | 0.05 | lasso | 5 | 0.04 | 9.3e-06 | -6.0 | 5.5 | 2.9e-08 | 0.17 | 0.51 | 0.48 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | RRAS2 | 0.06 | 0.02 | lasso | 5 | 0.04 | 2.2e-05 | 7.7 | 5.4 | 6.5e-08 | 0.87 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Artery Aorta | RRAS2 | 0.06 | 0.06 | enet | 10 | 0.03 | 5.6e-03 | 5.6 | 5.8 | 7.5e-09 | 0.27 | 0.17 | 0.11 | FALSE |
| 4 | GTEx | Artery Tibial | RRAS2 | 0.08 | 0.06 | lasso | 5 | 0.07 | 5.7e-06 | -5.4 | 5.4 | 5.6e-08 | 0.17 | 0.95 | 0.00 | FALSE |
| 5 | GTEx | Testis | RRAS2 | 0.18 | 0.13 | enet | 19 | 0.15 | 2.7e-07 | -5.0 | 6.0 | 1.7e-09 | 0.20 | 0.98 | 0.00 | FALSE |
| 6 | YFS | Blood | RRAS2 | 0.16 | 0.14 | enet | 53 | 0.19 | 8.5e-59 | 5.3 | -5.9 | 3.4e-09 | -0.65 | 1.00 | 0.00 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RRAS2 | 0.13 | 0.01 | blup | 11 | 0.05 | 4.0e-03 | 7.8 | 7.7 | 9.4e-15 | 0.80 | 0.00 | 0.93 | TRUE |