[Hub]/) : Traits : Hip circumference : ← →

chr16:3,301,360-5,706,977

Best TWAS P=2.59e-21 · Best GWAS P=1.34e-27 conditioned to 4.15e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-95P2.1 0.12 0.01 lasso 3 0.02 1.0e-02 6.0 -5.7 1.4e-08 0.00 0.05 0.05 FALSE
2 GTEx Artery Aorta UBN1 0.18 0.15 lasso 4 0.14 6.8e-08 6.0 -5.5 5.1e-08 -0.04 0.16 0.84 FALSE
3 GTEx Brain Cerebellar Hemisphere ZNF500 0.27 0.13 enet 13 0.12 4.4e-04 3.0 6.3 2.2e-10 0.00 0.13 0.66 TRUE
4 GTEx Brain Cortex ZNF500 0.18 0.02 enet 8 0.04 2.5e-02 -4.1 5.1 2.8e-07 0.05 0.08 0.14 FALSE
5 GTEx Cells Transformed fibroblasts RP11-95P2.1 0.13 0.11 lasso 3 0.12 2.0e-09 6.2 -6.5 5.6e-11 0.05 1.00 0.00 FALSE
6 GTEx Esophagus Mucosa UBN1 0.12 0.06 lasso 3 0.08 5.1e-06 5.7 -5.7 1.5e-08 -0.05 0.24 0.76 TRUE
7 GTEx Esophagus Muscularis UBN1 0.18 0.19 lasso 4 0.19 9.1e-12 6.0 -5.9 4.5e-09 -0.04 0.93 0.07 FALSE
8 GTEx Muscle Skeletal ZNF500 0.06 0.00 enet 15 0.00 2.8e-01 3.0 5.7 1.2e-08 0.05 0.06 0.16 FALSE
9 GTEx Nerve Tibial UBN1 0.14 0.12 lasso 4 0.11 5.6e-08 5.9 -5.9 3.4e-09 -0.04 0.61 0.39 FALSE
10 GTEx Skin Sun Exposed Lower leg PPL 0.10 0.04 lasso 6 0.02 5.7e-03 5.7 5.4 7.3e-08 0.05 0.08 0.71 FALSE
11 GTEx Skin Sun Exposed Lower leg UBN1 0.16 0.15 lasso 5 0.17 9.5e-14 6.0 -5.9 4.1e-09 -0.05 0.39 0.61 TRUE
12 GTEx Thyroid RP11-95P2.1 0.15 0.10 lasso 5 0.10 3.9e-08 6.9 -7.2 4.1e-13 0.03 0.94 0.00 TRUE
13 ROSMAP Brain Pre-frontal Cortex RP11-462G12.1 0.11 0.07 enet 18 0.06 1.1e-08 -10.5 -9.5 2.6e-21 0.86 0.00 1.00 TRUE
14 The Cancer Genome Atlas Colon Adenocarcinoma UBN1 0.05 0.04 enet 7 0.05 4.2e-04 -6.2 5.8 6.1e-09 0.06 0.03 0.65 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ROGDI 0.03 0.04 lasso 3 0.03 1.6e-04 5.2 -5.1 2.9e-07 0.01 0.04 0.88 FALSE