Best TWAS P=4.82e-10 · Best GWAS P=3.03e-10 conditioned to 0.000797
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | DLG4 | 0.12 | 0.05 | lasso | 4 | 0.05 | 2.3e-05 | -4.6 | 5.4 | 5.5e-08 | 0.74 | 0.23 | 0.74 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | EIF5A | 0.05 | 0.04 | blup | 52 | 0.03 | 1.5e-03 | 4.4 | -5.3 | 9.4e-08 | -0.08 | 0.03 | 0.29 | TRUE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | EIF5A | 0.10 | 0.02 | blup | 51 | 0.06 | 5.5e-04 | 4.0 | -5.5 | 3.4e-08 | -0.26 | 0.01 | 0.69 | FALSE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | EIF5A | 0.16 | 0.00 | blup | 50 | 0.03 | 5.0e-02 | -3.2 | -6.1 | 1.2e-09 | -0.25 | 0.01 | 0.17 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C17orf81 | 0.04 | 0.05 | enet | 8 | 0.04 | 1.2e-05 | -4.5 | -6.2 | 4.8e-10 | -0.67 | 0.06 | 0.89 | TRUE |