Best TWAS P=9.16e-10 · Best GWAS P=2.24e-08 conditioned to 0.358
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | DRG2 | 0.33 | 0.13 | enet | 29 | 0.17 | 6.1e-09 | -3.8 | 6.1 | 9.2e-10 | -0.12 | 0.13 | 0.83 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Female) | DRG2 | 0.05 | 0.00 | enet | 8 | -0.01 | 9.7e-01 | -4.5 | 5.6 | 1.9e-08 | -0.13 | 0.03 | 0.20 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | TOM1L2 | 0.05 | 0.00 | enet | 14 | 0.00 | 2.8e-01 | -4.3 | 5.8 | 7.6e-09 | -0.61 | 0.11 | 0.55 | FALSE |
| 4 | GTEx | Lung | DRG2 | 0.18 | 0.10 | enet | 18 | 0.09 | 1.9e-07 | -3.9 | 5.3 | 1.2e-07 | -0.06 | 0.68 | 0.21 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | RASD1 | 0.04 | 0.05 | blup | 49 | 0.04 | 4.5e-05 | -3.0 | 5.3 | 9.8e-08 | -0.82 | 0.10 | 0.79 | TRUE |