TWAS
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Traits
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Traits
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Hip circumference
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chr2:26,223,547-28,129,391
Best TWAS P=6.49e-09 · Best GWAS P=2.01e-08 conditioned to 1
26.5M
27M
27.5M
28M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
KCNK3
0.24
0.15
lasso
3
0.15
6.5e-19
5.5
-5.8
6.5e-09
0.98
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
FNDC4
0.13
0.06
lasso
2
0.05
1.1e-03
-5.1
5.3
8.6e-08
-0.10
0.00
0.89
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
SUPT7L
0.05
0.02
blup
28
0.04
5.2e-05
4.4
5.3
9.4e-08
-0.10
0.04
0.69
FALSE