Best TWAS P=6.49e-09 · Best GWAS P=2.01e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 5.5 | -5.8 | 6.5e-09 | 0.98 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SUPT7L | 0.05 | 0.02 | blup | 28 | 0.04 | 5.2e-05 | 4.4 | 5.3 | 9.4e-08 | -0.10 | 0.04 | 0.69 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FNDC4 | 0.13 | 0.06 | lasso | 2 | 0.05 | 1.1e-03 | -5.1 | 5.3 | 8.6e-08 | -0.10 | 0.00 | 0.89 | TRUE |