Best TWAS P=1.41e-08 · Best GWAS P=8.31e-09 conditioned to 0.954
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MLX | 0.03 | 0.03 | enet | 12 | 0.02 | 6.5e-04 | -4.9 | -5.6 | 1.9e-08 | 0.84 | 0.04 | 0.94 | FALSE |
| 2 | GTEx | Artery Coronary | RP11-400F19.6 | 0.15 | 0.02 | lasso | 3 | 0.03 | 4.1e-02 | -5.7 | 5.2 | 1.7e-07 | -0.95 | 0.02 | 0.76 | FALSE |
| 3 | GTEx | Brain Cerebellum | HSD17B1P1 | 0.17 | 0.16 | lasso | 4 | 0.20 | 1.7e-06 | -4.8 | -5.6 | 2.4e-08 | 0.83 | 0.08 | 0.88 | FALSE |
| 4 | GTEx | Thyroid | CTD-3193K9.3 | 0.05 | 0.02 | enet | 8 | 0.02 | 5.1e-03 | -4.6 | 5.1 | 2.9e-07 | -0.80 | 0.18 | 0.63 | FALSE |
| 5 | NTR | Blood | TUBG2 | 0.01 | 0.00 | blup | 247 | 0.01 | 4.0e-03 | -5.7 | 5.4 | 6.4e-08 | -0.68 | 0.03 | 0.94 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | CNTNAP1 | 0.06 | 0.05 | blup | 27 | 0.03 | 7.3e-03 | -4.8 | 5.1 | 3.0e-07 | -0.74 | 0.04 | 0.71 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | RND2 | 0.08 | 0.00 | enet | 16 | 0.02 | 3.5e-03 | -2.9 | 5.7 | 1.4e-08 | -0.14 | 0.00 | 0.00 | TRUE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | CNTNAP1 | 0.04 | 0.03 | blup | 27 | 0.05 | 2.7e-05 | -5.5 | 5.6 | 1.6e-08 | -0.87 | 0.02 | 0.97 | TRUE |