[Hub]/) : Traits : Hip circumference :

chr17:44,788,310-47,688,526

Best TWAS P=4.91e-12 · Best GWAS P=9.3e-12 conditioned to 0.000192

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDK5RAP3 0.15 0.12 bslmm 392 0.14 3.6e-16 5.46 -5.6 2.0e-08 -0.78 0.63 0.37 FALSE
2 GTEx Adipose Subcutaneous RP11-6N17.9 0.10 0.05 enet 14 0.05 6.8e-05 -4.18 -5.4 6.0e-08 -0.42 0.46 0.07 FALSE
3 GTEx Adipose Visceral Omentum MRPL45P2 0.24 0.00 enet 24 0.01 1.2e-01 4.83 -5.4 5.6e-08 -0.40 0.04 0.30 FALSE
4 GTEx Adipose Visceral Omentum RP11-6N17.9 0.13 0.04 enet 16 0.05 8.4e-04 -2.07 -5.2 2.5e-07 -0.47 0.25 0.34 FALSE
5 GTEx Artery Aorta RP11-6N17.9 0.23 0.12 enet 19 0.19 9.5e-11 -4.22 -5.2 1.8e-07 -0.42 0.99 0.01 FALSE
6 GTEx Artery Aorta RP11-6N17.10 0.20 0.07 enet 24 0.14 3.5e-08 -4.22 -6.1 1.1e-09 -0.43 0.47 0.16 FALSE
7 GTEx Brain Caudate basal ganglia RP11-6N17.9 0.45 -0.01 enet 28 0.16 3.3e-05 -0.19 -5.2 2.1e-07 -0.48 0.06 0.16 FALSE
8 GTEx Brain Cerebellar Hemisphere SNX11 0.25 0.19 enet 38 0.22 2.0e-06 3.24 -5.7 1.5e-08 -0.52 0.21 0.09 FALSE
9 GTEx Brain Cerebellar Hemisphere CDK5RAP3 0.22 0.10 lasso 6 0.09 2.6e-03 4.83 -6.1 1.3e-09 -0.74 0.07 0.46 FALSE
10 GTEx Brain Cerebellar Hemisphere RP11-6N17.10 0.21 0.16 lasso 5 0.13 3.8e-04 4.83 -5.5 3.7e-08 -0.73 0.08 0.50 FALSE
11 GTEx Brain Nucleus accumbens basal ganglia CDK5RAP3 0.21 0.04 lasso 4 0.02 7.2e-02 5.70 -5.9 4.1e-09 -0.78 0.07 0.44 FALSE
12 GTEx Brain Nucleus accumbens basal ganglia RP11-6N17.9 0.47 0.05 lasso 17 0.11 8.3e-04 5.03 -5.3 1.3e-07 -0.65 0.10 0.44 FALSE
13 GTEx Cells Transformed fibroblasts RP11-6N17.9 0.14 0.04 enet 17 0.08 2.3e-06 -4.22 -5.3 1.5e-07 -0.39 0.96 0.02 FALSE
14 GTEx Esophagus Gastroesophageal Junction CDK5RAP3 0.21 0.09 lasso 6 0.07 1.2e-03 -4.22 -6.2 6.6e-10 -0.30 0.09 0.50 FALSE
15 GTEx Esophagus Gastroesophageal Junction RP11-6N17.9 0.18 0.14 lasso 3 0.09 4.9e-04 -4.22 -5.5 4.2e-08 -0.49 0.03 0.72 FALSE
16 GTEx Heart Atrial Appendage CDK5RAP3 0.13 0.00 enet 18 0.04 5.1e-03 3.66 -6.9 4.9e-12 -0.42 0.09 0.05 TRUE
17 GTEx Muscle Skeletal AC003665.1 0.05 0.03 enet 8 0.03 1.4e-03 5.58 6.6 5.0e-11 0.63 0.12 0.73 FALSE
18 GTEx Pancreas CDK5RAP3 0.11 -0.01 lasso 4 0.02 5.1e-02 4.83 -5.5 4.4e-08 -0.48 0.09 0.19 FALSE
19 GTEx Pancreas EFCAB13 0.27 0.12 enet 15 0.11 2.4e-05 -4.54 -5.3 1.4e-07 -0.03 0.05 0.81 FALSE
20 GTEx Stomach RP11-6N17.9 0.13 0.02 lasso 6 0.04 8.0e-03 5.51 -5.8 6.9e-09 -0.70 0.10 0.74 FALSE
21 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.67 5.7 1.3e-08 0.78 0.15 0.71 FALSE
22 GTEx Thyroid CDK5RAP3 0.21 0.14 lasso 5 0.18 1.6e-13 -4.22 -5.3 1.2e-07 -0.51 1.00 0.00 FALSE
23 GTEx Thyroid RP11-6N17.9 0.22 0.14 lasso 5 0.14 5.2e-11 -4.22 -5.2 2.6e-07 -0.44 1.00 0.00 FALSE
24 GTEx Thyroid RP11-6N17.10 0.19 0.12 lasso 5 0.13 3.0e-10 -4.22 -5.3 1.1e-07 -0.47 1.00 0.00 FALSE
25 YFS Blood UBE2Z 0.06 0.03 enet 19 0.06 1.5e-18 2.48 5.6 2.6e-08 0.10 0.68 0.06 TRUE
26 The Cancer Genome Atlas Breast Invasive Carcinoma CDK5RAP3 0.05 0.03 lasso 2 0.02 1.8e-05 5.51 -5.6 2.2e-08 -0.76 0.00 1.00 FALSE
27 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CBX1 0.03 0.01 lasso 3 0.01 8.7e-03 5.70 -5.1 2.8e-07 -0.80 0.02 0.52 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma SNX11 0.07 0.07 blup 53 0.08 1.4e-09 3.45 -5.2 1.7e-07 -0.58 0.94 0.05 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.72 -5.6 1.7e-08 -0.84 0.04 0.95 FALSE
30 The Cancer Genome Atlas Prostate Adenocarcinoma CDK5RAP3 0.06 0.00 blup 62 0.03 1.0e-03 -2.72 -5.8 6.3e-09 -0.35 0.01 0.70 FALSE