Best TWAS P=6.38e-13 · Best GWAS P=4.75e-12 conditioned to 0.00181
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | RPTOR | 0.14 | 0.05 | enet | 27 | 0.09 | 8.4e-09 | -6.0 | -7.2 | 6.4e-13 | 0.62 | 0.43 | 0.56 | TRUE |
2 | GTEx | Muscle Skeletal | CTD-2561B21.4 | 0.06 | 0.04 | lasso | 7 | 0.03 | 2.3e-04 | -5.9 | -6.6 | 4.4e-11 | 0.64 | 0.14 | 0.79 | FALSE |