Best TWAS P=1.06e-08 · Best GWAS P=1.79e-09 conditioned to 2.26e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | PDE4C | 0.39 | 0.44 | lasso | 2 | 0.43 | 5.8e-21 | -5.4 | -5.4 | 7.4e-08 | -0.04 | 0.03 | 0.97 | FALSE |
2 | GTEx | Testis | AC068499.10 | 0.38 | 0.41 | lasso | 3 | 0.40 | 6.8e-19 | -5.4 | -5.5 | 5.1e-08 | -0.04 | 0.03 | 0.97 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MAST3 | 0.02 | 0.02 | lasso | 3 | 0.01 | 1.5e-02 | 5.6 | -5.7 | 1.2e-08 | -0.04 | 0.01 | 0.94 | FALSE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | MAST3 | 0.04 | 0.02 | lasso | 2 | 0.00 | 3.4e-01 | 5.6 | -5.7 | 1.1e-08 | -0.04 | 0.01 | 0.88 | TRUE |