Best TWAS P=2.73e-11 · Best GWAS P=2e-09 conditioned to 0.262
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FUT1 | 0.15 | 0.13 | lasso | 2 | 0.15 | 2.1e-17 | 5.1 | -5.1 | 3.1e-07 | 0.52 | 0.18 | 0.82 | FALSE |
| 2 | GTEx | Adrenal Gland | RASIP1 | 0.20 | 0.11 | lasso | 4 | 0.10 | 2.4e-04 | 5.2 | -5.4 | 7.3e-08 | 0.74 | 0.06 | 0.87 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RASIP1 | 0.15 | 0.04 | lasso | 6 | 0.08 | 2.9e-05 | -5.7 | -6.7 | 2.7e-11 | 0.80 | 0.01 | 0.98 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | RASIP1 | 0.21 | 0.13 | enet | 19 | 0.17 | 1.1e-13 | 5.0 | -6.7 | 2.9e-11 | 0.89 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Testis | RASIP1 | 0.29 | 0.20 | lasso | 8 | 0.30 | 7.5e-14 | 5.0 | -5.6 | 1.8e-08 | 0.85 | 0.04 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | FUT2 | 0.05 | 0.01 | blup | 52 | 0.01 | 6.1e-02 | -5.8 | 5.9 | 2.9e-09 | -0.83 | 0.00 | 0.85 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | IZUMO1 | 0.16 | 0.17 | lasso | 7 | 0.15 | 1.4e-06 | 4.9 | -5.1 | 3.0e-07 | 0.77 | 0.09 | 0.90 | FALSE |