Best TWAS P=1.28e-09 · Best GWAS P=1.36e-07 conditioned to 0.112
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ACYP2 | 0.06 | 0.02 | blup | 561 | 0.03 | 4.8e-05 | -4.5 | 6.1 | 1.3e-09 | -0.68 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Artery Aorta | HMGB1P31 | 0.17 | 0.05 | enet | 31 | 0.07 | 7.4e-05 | 3.3 | -5.3 | 9.6e-08 | 0.56 | 0.28 | 0.56 | FALSE |
| 3 | GTEx | Colon Sigmoid | ACYP2 | 0.35 | 0.09 | enet | 21 | 0.18 | 4.6e-07 | -2.8 | 5.2 | 2.4e-07 | -0.70 | 0.10 | 0.87 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | AC008280.3 | 0.13 | 0.00 | enet | 21 | 0.08 | 2.4e-04 | -2.8 | 5.3 | 1.4e-07 | -0.45 | 0.07 | 0.04 | FALSE |
| 5 | GTEx | Testis | HMGB1P31 | 0.17 | 0.01 | enet | 21 | 0.02 | 4.6e-02 | -2.8 | -5.7 | 1.4e-08 | 0.60 | 0.12 | 0.58 | FALSE |