[Hub]/) : Traits : Hip circumference :

chr2:35,883,253-37,567,226

Best TWAS P=4.69e-11 · Best GWAS P=1.74e-10 conditioned to 1.63e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FEZ2 0.16 0.24 lasso 2 0.22 1.3e-26 6.2 -6.2 4.6e-10 0.04 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 5.8 6.1 8.9e-10 -0.09 0.08 0.85 FALSE
3 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 5.8 -6.6 4.7e-11 0.05 0.05 0.93 TRUE
4 GTEx Artery Tibial RP11-78I14.1 0.10 0.08 enet 16 0.07 4.2e-06 5.8 -5.7 1.0e-08 0.02 0.11 0.84 FALSE
5 GTEx Brain Cerebellar Hemisphere CRIM1 0.36 0.21 lasso 5 0.16 5.4e-05 5.6 5.8 8.3e-09 0.00 0.11 0.69 FALSE
6 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 5.3 5.4 5.6e-08 0.00 0.10 0.88 FALSE
7 GTEx Brain Cerebellar Hemisphere AC007401.1 0.40 0.26 lasso 4 0.22 2.3e-06 5.6 5.6 2.8e-08 0.00 0.13 0.82 FALSE
8 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 5.4 5.6 2.3e-08 0.01 0.06 0.77 FALSE
9 GTEx Brain Cerebellum AC007401.1 0.27 0.21 enet 5 0.20 1.5e-06 5.6 5.6 2.5e-08 -0.01 0.16 0.76 FALSE
10 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 4.5 5.2 1.5e-07 0.01 0.11 0.70 FALSE
11 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 5.3 5.6 2.3e-08 0.00 0.27 0.65 FALSE
12 NTR Blood CRIM1 0.09 0.10 lasso 6 0.11 3.1e-32 5.0 -5.4 8.3e-08 0.01 0.46 0.54 FALSE
13 ROSMAP Brain Pre-frontal Cortex FEZ2 0.41 0.55 lasso 5 0.58 3.1e-93 5.7 -5.6 2.3e-08 0.01 0.33 0.67 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 5.3 -6.4 1.6e-10 0.05 0.01 0.96 FALSE
15 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FEZ2 0.06 0.05 lasso 4 0.04 3.3e-03 5.4 -5.4 7.9e-08 0.01 0.04 0.81 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 5.7 -5.7 1.3e-08 0.03 0.04 0.96 FALSE