[Hub]/) : Traits : Hip circumference :

chr3:182,655,858-184,274,877

Best TWAS P=2.3e-09 · Best GWAS P=7.6e-10 conditioned to 0.491

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KLHL24 0.42 0.60 bslmm 493 0.66 4.5e-107 -5.5 -5.9 4.7e-09 -0.12 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous KLHL24 0.15 0.10 lasso 6 0.10 1.4e-08 -5.6 5.9 3.0e-09 0.15 0.03 0.97 TRUE
3 GTEx Brain Caudate basal ganglia KLHL24 0.22 0.21 lasso 3 0.19 3.5e-06 -5.6 5.6 2.3e-08 0.13 0.03 0.95 FALSE
4 GTEx Brain Cerebellum KLHL24 0.52 0.14 enet 26 0.16 1.9e-05 -5.6 5.4 6.7e-08 0.13 0.03 0.96 TRUE
5 GTEx Brain Cortex KLHL24 0.21 0.15 lasso 3 0.07 6.1e-03 -5.6 5.9 3.5e-09 0.17 0.03 0.90 FALSE
6 GTEx Brain Hypothalamus KLHL24 0.22 0.24 lasso 2 0.19 3.3e-05 -5.6 5.6 2.4e-08 0.10 0.04 0.74 FALSE
7 GTEx Breast Mammary Tissue KLHL24 0.25 0.13 lasso 5 0.11 3.4e-06 -5.6 5.8 8.2e-09 0.14 0.03 0.97 FALSE
8 GTEx Esophagus Muscularis KLHL24 0.10 0.12 lasso 1 0.09 4.4e-06 -5.6 5.6 2.0e-08 0.14 0.03 0.97 FALSE
9 GTEx Nerve Tibial KLHL24 0.08 0.06 lasso 3 0.05 1.5e-04 -5.5 5.5 3.9e-08 0.13 0.04 0.94 FALSE
10 GTEx Skin Sun Exposed Lower leg KLHL24 0.09 0.06 lasso 10 0.05 9.5e-05 -5.6 5.6 2.2e-08 0.14 0.03 0.96 FALSE
11 GTEx Testis KLHL24 0.17 0.10 lasso 4 0.10 4.0e-05 -5.6 5.6 1.9e-08 0.14 0.03 0.97 FALSE
12 METSIM Adipose MAP6D1 0.06 0.05 bslmm 473 0.06 2.3e-09 4.9 5.2 2.1e-07 0.27 0.96 0.04 TRUE
13 YFS Blood KLHL24 0.02 0.01 lasso 2 0.01 1.4e-03 -4.9 5.3 1.4e-07 0.12 0.04 0.95 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 4.7 5.7 1.2e-08 0.70 0.03 0.94 TRUE
15 The Cancer Genome Atlas Brain Lower Grade Glioma KLHL24 0.05 0.05 blup 53 0.05 1.1e-06 -5.5 5.8 5.5e-09 0.14 0.04 0.96 TRUE
16 The Cancer Genome Atlas Lung Adenocarcinoma PSMD2 0.09 0.02 blup 50 0.05 1.2e-06 -3.6 6.0 2.3e-09 0.46 0.15 0.28 TRUE
17 The Cancer Genome Atlas Testicular Germ Cell Tumors KLHL24 0.16 0.16 blup 53 0.21 4.3e-08 -5.6 5.6 1.9e-08 0.13 0.03 0.97 FALSE