Best TWAS P=7.66e-10 · Best GWAS P=3.68e-07 conditioned to 0.473
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PCYT1A | 0.11 | 0.03 | lasso | 3 | 0.00 | 0.3920 | 5.1 | -5.3 | 1.5e-07 | -0.96 | 0.02 | 0.83 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | UBXN7 | 0.20 | 0.00 | enet | 16 | 0.02 | 0.0352 | -4.7 | -5.1 | 2.9e-07 | -0.65 | 0.02 | 0.88 | FALSE |
| 3 | GTEx | Stomach | SLC51A | 0.13 | 0.06 | enet | 12 | 0.03 | 0.0193 | 4.7 | -5.7 | 1.0e-08 | -0.86 | 0.01 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN7 | 0.02 | 0.01 | blup | 45 | 0.02 | 0.0042 | 3.5 | -5.3 | 1.1e-07 | -0.76 | 0.02 | 0.49 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PCYT1A | 0.05 | 0.00 | blup | 68 | 0.02 | 0.0060 | -4.2 | -5.2 | 2.3e-07 | -0.63 | 0.02 | 0.42 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PCYT1A | 0.12 | 0.05 | blup | 68 | 0.06 | 0.0002 | 4.8 | -6.2 | 7.7e-10 | -0.75 | 0.01 | 0.90 | TRUE |