Best TWAS P=4.65e-10 · Best GWAS P=5.99e-12 conditioned to 0.00142
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAM53A | 0.08 | 0.05 | lasso | 6 | 0.03 | 6.9e-05 | -5.1 | -5.2 | 2.0e-07 | -0.54 | 0.40 | 0.49 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | FAM53A | 0.05 | 0.03 | blup | 56 | 0.04 | 1.8e-04 | 4.3 | 6.2 | 4.6e-10 | 0.79 | 0.01 | 0.96 | TRUE |