Best TWAS P=4.3e-08 · Best GWAS P=2.17e-08 conditioned to 0.0455
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Vagina | AC021860.1 | 0.42 | 0.04 | lasso | 12 | 0.07 | 1.2e-02 | 3.3 | 5.5 | 4.3e-08 | -0.48 | 0.08 | 0.15 | TRUE |
| 2 | GTEx | Vagina | RP11-617D20.1 | 0.31 | 0.01 | lasso | 8 | 0.02 | 1.4e-01 | 3.2 | 5.1 | 2.8e-07 | -0.78 | 0.05 | 0.38 | FALSE |
| 3 | GTEx | Whole Blood | RP11-617D20.1 | 0.14 | 0.06 | lasso | 3 | 0.05 | 4.2e-05 | -5.3 | 5.4 | 5.4e-08 | -0.92 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | TLR1 | 0.13 | 0.13 | enet | 3 | 0.08 | 2.6e-03 | 5.2 | -5.4 | 8.0e-08 | 0.24 | 0.01 | 0.74 | TRUE |