Hub : Genes

FAM53A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0750 0.0300 1.2e-03 0.046 0.013 0.019 0.020 0.032 2.5e-06 8.1e-03 2.1e-03 1.5e-03 6.9e-05
2 GTEx Adipose Subcutaneous 0.1390 0.0420 6.6e-05 0.095 NA 0.056 NA 0.079 3.3e-08 NA 2.2e-05 NA 4.8e-07
3 GTEx Artery Tibial 0.1311 0.0415 2.0e-04 0.111 NA 0.091 NA 0.101 5.3e-09 NA 1.3e-07 NA 2.4e-08
4 GTEx Cells EBV-transformed lymphocytes 0.4140 0.0800 4.1e-07 0.240 NA 0.122 NA 0.258 2.1e-08 NA 8.8e-05 NA 5.8e-09
5 GTEx Cells Transformed fibroblasts 0.2250 0.0610 2.4e-06 0.061 NA 0.060 NA 0.058 2.5e-05 NA 2.7e-05 NA 3.7e-05
6 GTEx Colon Transverse 0.1940 0.0630 3.9e-04 0.092 NA 0.022 NA 0.043 3.9e-05 NA 3.1e-02 NA 3.9e-03
7 GTEx Esophagus Muscularis 0.1890 0.0710 1.7e-03 0.003 NA 0.011 NA 0.006 1.9e-01 NA 6.8e-02 NA 1.3e-01
8 GTEx Muscle Skeletal 0.3500 0.0484 0.0e+00 0.246 NA 0.321 NA 0.297 6.2e-24 NA 3.7e-32 NA 1.8e-29
9 GTEx Pancreas 0.2190 0.0690 5.3e-04 0.057 NA 0.082 NA 0.115 2.0e-03 NA 2.4e-04 NA 1.4e-05
10 GTEx Skin Sun Exposed Lower leg 0.0790 0.0330 5.4e-03 0.089 NA 0.053 NA 0.070 8.2e-08 NA 3.0e-05 NA 2.1e-06
11 GTEx Stomach 0.1560 0.0630 5.4e-03 0.003 NA 0.011 NA 0.008 2.2e-01 NA 8.8e-02 NA 1.2e-01
12 GTEx Testis 0.3700 0.0680 6.2e-10 0.291 NA 0.347 NA 0.310 2.4e-13 NA 3.7e-16 NA 2.6e-14
13 GTEx Thyroid 0.3010 0.0480 0.0e+00 0.327 NA 0.293 NA 0.313 1.1e-25 NA 1.1e-22 NA 1.8e-24
14 GTEx Whole Blood 0.1630 0.0440 4.5e-07 0.096 NA 0.073 NA 0.094 3.8e-09 NA 2.9e-07 NA 5.4e-09
15 METSIM Adipose 0.0671 0.0223 9.3e-06 0.060 0.045 0.047 0.051 0.058 2.1e-09 2.5e-07 1.2e-07 3.4e-08 4.5e-09
16 YFS Blood 0.2073 0.0360 0.0e+00 0.204 0.211 0.222 0.213 0.213 9.0e-65 2.7e-67 5.6e-71 6.0e-68 7.6e-68
17 TCGA Bladder Urothelial Carcinoma 0.0860 0.0330 1.3e-06 0.060 0.083 0.074 NA 0.069 7.8e-06 1.5e-07 7.1e-07 NA 1.8e-06
18 TCGA Breast Invasive Carcinoma 0.0217 0.0102 1.4e-04 0.026 0.020 0.019 NA 0.021 3.0e-06 4.0e-05 7.3e-05 NA 3.4e-05
19 TCGA Colon Adenocarcinoma 0.1210 0.0490 3.2e-06 0.112 0.083 0.082 NA 0.109 5.5e-07 1.6e-05 1.8e-05 NA 7.3e-07
20 TCGA Esophageal Carcinoma 0.2130 0.0940 2.3e-04 0.042 0.071 0.025 NA 0.015 1.8e-02 2.8e-03 5.6e-02 NA 1.1e-01
21 TCGA Head and Neck Squamous Cell Carcinoma 0.0884 0.0378 1.2e-07 0.070 0.067 0.070 NA 0.064 2.6e-08 5.6e-08 2.6e-08 NA 9.7e-08
22 TCGA Kidney Renal Clear Cell Carcinoma 0.0443 0.0251 1.4e-03 0.001 0.025 0.025 NA 0.008 2.1e-01 6.5e-04 6.7e-04 NA 4.0e-02
23 TCGA Brain Lower Grade Glioma 0.0295 0.0174 5.8e-03 -0.001 0.015 0.002 NA 0.000 4.3e-01 6.8e-03 1.6e-01 NA 3.0e-01
24 TCGA Lung Adenocarcinoma 0.0902 0.0347 1.6e-08 0.072 0.063 0.048 NA 0.057 9.2e-09 7.8e-08 2.5e-06 NA 3.3e-07
25 TCGA Lung Squamous Cell Carcinoma 0.0971 0.0351 4.1e-09 0.029 0.094 0.086 NA 0.072 3.0e-04 7.3e-11 5.5e-10 NA 1.3e-08
26 TCGA Ovarian Serous Cystadenocarcinoma 0.0600 0.0330 5.8e-03 0.044 0.030 0.023 NA 0.034 5.8e-04 3.9e-03 1.1e-02 NA 2.4e-03
27 TCGA Prostate Adenocarcinoma 0.1596 0.0524 3.0e-14 0.151 0.142 0.148 NA 0.137 1.7e-15 1.2e-14 3.0e-15 NA 3.5e-14
28 TCGA Rectum Adenocarcinoma 0.2650 0.1080 1.9e-03 0.137 0.046 0.103 NA 0.087 4.2e-04 3.1e-02 2.1e-03 NA 4.5e-03
29 TCGA Stomach Adenocarcinoma 0.1110 0.0410 1.9e-08 0.126 0.116 0.117 NA 0.128 2.1e-09 1.0e-08 8.3e-09 NA 1.6e-09
30 TCGA Thyroid Carcinoma 0.0500 0.0230 1.7e-04 0.029 0.036 0.022 NA 0.018 7.8e-04 1.8e-04 2.6e-03 NA 6.7e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Bipolar Disorder (2018) 0.1 0.2 0.7 0.3 0.2 0.8 0.4 -0.2 0.3 -0.1 0.4 -0.3 0.5 0.1 -0.5 -0.3 0.3 0.6 -0.0 0.2 0.2 0.4 0.0 -0.4 0.5 0.4 0.1 -0.2 0.0 0.5 0.4 0.5 -0.8
Bipolar Disorder or Schizophrenia 0.2 0.5 1.9 1.4 0.4 0.8 0.7 0.0 0.7 0.8 0.4 0.2 0.5 0.5 -1.1 -0.3 0.9 0.7 0.5 0.5 0.8 0.5 0.7 0.3 1.0 0.7 0.7 0.3 0.0 0.9 0.9 0.7 -0.5
Depressed Affect (Nagel 2018) 0.1 0.3 1.1 0.6 -0.3 0.8 -0.3 0.9 -0.3 1.0 -0.2 0.3 -0.6 -0.1 0.9 0.5 -0.1 -0.3 0.2 0.4 -0.1 -0.1 0.9 0.6 0.2 0.9 0.5 0.1 -0.7 0.2 0.3 -0.2 1.0
Depression (Nagel 2018) 1.1 1.7 3.0 1.7 1.3 0.2 1.4 1.5 1.5 1.3 1.7 1.5 1.2 1.5 -1.1 -1.1 1.4 1.3 1.7 0.9 1.3 1.3 1.2 1.1 0.6 1.1 1.3 1.2 1.1 1.6 1.5 1.3 -0.7
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.9 -0.0 -0.3 -0.9 -0.6 -0.1 -0.5 -0.1 -1.0 0.0 -0.5 -0.4 0.3 0.2 -0.7 -0.6 -0.1 -0.8 -0.7 -0.6 -0.6 -0.3 -0.8 -0.8 -0.3 -0.2 -0.5 -0.7 -0.8 -0.6 0.3
Neuroticism (Nagel 2018) 0.1 0.2 1.2 1.1 0.3 0.5 0.1 0.2 0.1 0.4 0.3 0.9 -0.1 0.3 0.3 0.2 0.4 0.1 0.7 0.2 0.2 0.4 0.6 0.5 -0.3 0.6 0.7 0.7 -0.3 0.5 0.5 0.1 0.6
Schizophrenia (2018) 0.2 0.5 2.3 1.5 0.3 0.3 0.6 0.2 0.6 1.0 0.3 0.5 0.2 0.5 -1.0 -0.2 0.9 0.4 0.8 0.5 0.8 0.4 1.1 1.1 0.8 0.5 1.1 0.1 0.2 0.7 1.1 0.5 -0.0
Schizophrenia vs Biploar Disorder 0.1 0.1 0.6 -0.4 -0.4 -0.3 -0.0 0.0 -0.0 -0.6 -0.5 -0.5 -0.3 -0.2 0.0 0.2 0.1 -0.5 -0.3 -0.3 -0.1 -0.3 -0.2 0.4 -0.3 -0.6 0.3 -0.8 0.0 -0.6 0.0 -0.2 -0.1
Worry (Nagel 2018) 0.6 1.2 3.2 1.5 1.2 -1.1 1.2 -0.2 1.2 -0.8 0.9 1.6 0.9 1.4 -1.5 -1.1 1.5 0.9 1.8 0.3 1.5 1.2 0.1 0.6 -0.7 -0.3 0.9 1.0 0.9 0.7 1.1 1.0 -1.3
Alzheimer’s Disease (in mother) 0.4 0.5 2.5 1.1 0.7 -1.6 0.6 0.5 0.4 -1.0 0.1 0.9 0.4 0.8 -1.1 -0.4 0.8 0.2 0.8 0.0 0.7 0.6 0.3 0.3 -0.6 -0.4 0.7 0.9 0.3 0.4 0.7 0.7 -0.5
Alzheimer’s Disease (in father) 0.6 0.6 2.2 -0.8 -0.8 0.8 -0.9 -0.4 -0.9 0.9 -0.9 -0.3 -1.0 -0.7 1.1 1.0 -0.9 -0.9 -1.1 -0.1 -0.9 -0.6 0.1 0.1 -0.0 0.4 -0.2 -0.4 -1.1 -0.6 -0.7 -1.0 1.5
Alzheimer’s Disease (including proxy) 0.2 0.3 1.6 0.8 -0.2 -1.3 -0.3 -0.4 -0.3 -0.9 -0.8 0.1 -0.3 -0.0 -0.2 0.5 -0.1 -0.5 0.1 -0.9 -0.1 -0.3 -0.4 -0.4 -1.2 -1.0 -0.2 -0.0 -0.5 -0.3 -0.2 -0.2 -0.3
Crohns Disease (2017) 0.1 0.2 1.7 -0.3 0.1 1.3 0.4 -0.1 0.3 -0.3 0.8 -0.5 0.6 0.2 -0.5 -0.5 0.3 0.4 0.1 0.3 0.2 0.0 0.2 -0.2 0.9 0.6 0.2 -0.5 0.7 0.2 0.2 0.3 -0.5
Irritable Bowel Disease (IBD) 0.7 1.6 3.8 0.2 1.1 0.5 1.7 0.2 1.6 -0.5 1.5 0.1 1.7 1.4 -1.9 -1.7 1.8 1.4 1.1 1.0 1.6 1.2 0.5 0.6 1.6 0.7 0.8 0.4 1.9 1.1 1.3 1.5 -1.6
Ulcerative Colitis (UC) 1.5 2.8 6.6 1.2 1.7 -0.4 2.3 0.6 2.2 -0.4 1.6 1.0 2.0 1.9 -2.6 -2.0 2.4 1.7 1.8 1.1 2.4 1.8 0.5 0.9 1.0 0.4 1.3 1.4 2.2 1.6 1.9 2.0 -2.1
Major Depression (MDD) 0.3 0.4 1.9 -0.2 0.3 0.0 1.1 0.0 1.4 1.2 0.0 -0.4 0.9 0.9 -0.6 -0.8 0.0 1.1 0.7 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.1 0.1 0.9 -0.4 0.1 0.2 0.2 0.3 0.1 0.9 0.3 0.2 0.1 -0.0 -0.2 -0.2 0.2 0.1 -0.7 0.5 0.2 0.2 0.3 -0.1 0.6 0.2 -0.1 0.7 0.1 0.1 -0.0 0.2 0.6
Verbal and Numeric Reasoning (VNR) 0.7 1.7 4.1 -0.7 -1.1 -0.5 -1.6 -0.9 -1.5 0.2 -1.8 -0.1 -1.5 -1.2 1.2 1.4 -1.7 -1.6 -1.2 -1.3 -1.6 -1.4 -0.7 -0.9 -1.4 -0.8 -0.6 0.0 -1.9 -1.4 -1.6 -1.5 2.0
Breast Cancer 0.6 1.5 9.4 2.5 0.9 -1.1 1.3 1.0 1.5 -0.3 0.6 0.5 1.2 1.1 -1.2 -1.2 1.5 0.9 1.8 -0.6 1.3 0.6 -0.8 -0.4 -1.0 -1.2 0.4 -0.2 1.3 0.6 1.3 1.0 -3.1
Ovarian Cancer 0.1 0.1 0.4 0.2 0.4 -0.1 0.2 0.3 0.3 -0.1 0.3 0.0 0.5 -0.1 -0.2 -0.5 0.3 0.6 0.3 0.5 0.3 0.2 0.4 0.2 0.6 -0.0 -0.1 0.1 0.6 0.5 0.1 0.4 -0.2
Prostate Cancer 0.9 1.3 4.6 -0.2 1.0 1.6 1.0 1.3 1.0 0.4 1.4 1.0 0.9 0.9 -0.3 -0.6 1.1 0.9 0.8 1.8 1.1 1.1 1.7 1.2 1.8 2.2 1.3 1.1 0.8 0.9 1.0 0.9 0.9
Age at First Birth 0.4 0.6 1.8 0.3 -0.5 -0.8 -0.9 0.2 -1.3 0.0 -1.3 -0.0 -0.7 -0.8 0.8 0.7 -0.8 -0.9 -0.9 -0.8 -0.9 -0.9 -0.4 -0.6 -1.2 -0.8 -0.7 -0.1 -0.8 -0.5 -0.7 -0.7 0.4
Bipolar Disorder (2011) 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 -0.1 -0.1 0.4 -0.3 0.7 0.9 -0.1 0.4 0.0 0.7 -0.1 0.2 0.3
Body Mass Index (BMI) (2010) 0.1 0.1 1.2 0.2 -0.2 0.5 -0.1 0.5 -0.3 1.1 0.0 -0.4 -0.0 -0.2 0.1 0.0 -0.2 -0.1 -0.0 0.1 -0.3 -0.3 -0.2 -0.4 0.5 0.1 -0.7 0.2 0.1 0.1 -0.3 -0.1 -0.0
Coronary Artery Disease (CAD) 0.1 0.1 0.5 0.0 0.2 -0.7 0.0 0.0 0.2 -0.7 -0.1 -0.2 0.2 0.1 -0.4 -0.2 0.0 -0.1 0.1 0.3 0.2 0.2 -0.2 0.2 0.1 -0.4 -0.2 0.2 0.0 -0.3 -0.1 0.0 -0.0
Crohns Disease (2012) 0.2 0.3 2.4 -1.5 -0.5 0.9 -0.1 -1.1 -0.1 -0.2 0.0 -1.1 -0.0 -0.5 -0.2 0.0 -0.2 -0.0 -0.5 0.3 -0.3 -0.2 -0.2 -0.2 1.0 0.1 -0.6 -0.7 0.0 -0.5 -0.5 -0.2 0.1
Mean Putamen Volume 0.9 1.1 2.3 0.8 1.0 0.3 1.0 1.5 0.9 0.7 1.1 1.3 0.8 1.0 -0.9 -0.9 1.1 0.9 0.8 1.2 0.9 0.9 1.4 1.5 1.2 1.0 1.1 1.4 0.8 1.2 1.0 0.9 0.5
Fasting Glucose 0.3 0.4 2.8 -0.2 -0.6 1.1 -0.5 -1.0 -0.7 0.1 -0.5 -0.6 -0.8 -0.5 0.3 0.6 -0.4 -0.5 -0.3 0.6 -0.7 -0.1 0.3 -0.4 0.5 1.1 0.1 0.3 -0.8 -0.3 -0.5 -0.5 1.7
HbA1C 0.7 0.7 4.2 -0.9 -0.2 -1.3 -1.0 -1.0 -0.8 -2.0 -1.1 -1.1 -0.7 -0.4 -0.2 0.6 -1.9 -0.8 -0.5 -0.3 -0.5 -0.1 -0.0 0.5 -0.6 -0.5 0.0 0.2 -0.8 -1.0 -0.8 -0.5 1.1
HDL Cholesterol 0.2 0.3 1.5 -1.2 0.1 0.6 -0.3 -0.1 -0.3 0.3 0.1 -0.0 0.2 -0.3 0.2 -0.1 -0.5 0.4 -0.6 0.6 -0.4 0.2 0.6 0.6 1.0 0.8 -0.0 0.3 0.0 0.3 -0.5 0.2 1.2
LDL Cholesterol 0.2 0.3 1.1 -0.4 -0.4 -1.0 -0.3 -0.7 -0.3 -0.5 -0.6 -0.5 -0.3 -0.5 0.4 0.4 -0.1 -0.4 -0.4 -0.6 -0.1 -0.3 -0.8 -0.4 -0.5 -1.0 -0.6 -0.9 0.0 -0.6 -0.2 -0.3 -0.7
Lupus 0.3 0.5 2.7 -0.1 0.3 0.8 0.4 0.9 0.1 1.1 0.3 -0.3 0.6 -0.0 -0.3 -0.6 0.2 0.8 -0.0 1.3 0.3 0.4 1.1 0.8 1.7 1.2 0.2 -0.0 0.7 0.8 0.5 0.6 0.1
Neuroticism (2016) 0.1 0.1 0.8 -0.2 -0.2 -0.3 0.2 -0.4 0.4 -0.7 0.0 0.3 -0.5 0.1 0.7 0.3 0.9 -0.1 -0.1 -0.3 -0.3 0.3 0.0 -0.2 -0.8 -0.1 0.3 -0.4 0.0 -0.5 -0.1 -0.1 0.0
Primary Biliary Cirrhosis 3.1 4.4 11.2 -1.7 -2.1 -1.4 -1.7 -2.8 -1.7 -1.5 -2.6 -3.0 -1.6 -1.9 0.5 1.7 -1.8 -1.8 -1.7 -2.6 -1.7 -2.1 -3.3 -2.4 -1.6 -2.7 -2.7 -2.8 -1.1 -2.3 -2.2 -1.8 -1.7
Rheumatoid Arthritis 1.4 1.9 3.6 1.1 1.1 0.8 1.5 1.4 1.8 1.5 1.7 0.8 1.1 1.4 -1.2 -1.3 1.6 1.3 1.3 1.9 1.5 1.2 1.7 1.1 1.9 1.7 1.3 0.6 1.3 1.3 1.7 1.1 -0.5
Schizophrenia (2014) 0.1 0.1 0.7 0.8 -0.1 -0.0 0.3 -0.1 0.2 0.2 -0.4 -0.4 0.1 0.0 -0.7 0.1 0.6 0.3 0.2 -0.3 0.2 0.1 0.0 0.2 0.0 -0.4 0.4 -0.7 0.2 0.2 0.5 0.4 -0.9
Triglycerides 0.1 0.1 0.5 -0.7 0.2 0.6 0.3 -0.6 0.5 0.2 0.3 -0.2 0.3 0.3 -0.0 -0.1 0.2 0.3 0.2 0.7 0.1 0.4 0.3 -0.0 0.6 0.6 0.3 -0.4 0.0 -0.2 0.3 0.1 -0.1
Type 2 Diabetes (T2D) (2012) 3.4 3.9 8.1 2.7 2.2 0.1 2.3 1.7 2.3 0.1 2.3 2.0 2.0 2.3 -2.1 -2.1 2.1 2.1 2.8 1.4 1.9 2.0 1.6 1.9 1.0 1.1 2.2 1.4 2.0 2.1 2.3 2.1 -1.5
Ulcerative Colitis 2.4 3.5 7.8 1.0 1.9 -1.2 2.5 1.1 2.4 -0.7 1.6 1.2 2.1 2.2 -2.8 -2.1 2.8 2.0 1.9 1.6 2.6 2.3 0.5 1.3 1.2 0.1 1.3 1.7 2.4 1.6 2.0 2.4 -2.1
Blood Eosinophil Count 1.1 8.4 15.9 -0.5 -2.6 -2.9 -2.8 -2.4 -2.5 -2.6 -3.4 -2.2 -2.9 -2.8 2.5 2.7 -2.7 -3.4 -2.0 -3.9 -2.8 -3.0 -3.8 -3.3 -4.0 -3.7 -3.5 -2.0 -2.9 -3.1 -3.0 -3.1 -0.6
Blood Platelet Count 0.1 0.8 2.2 -1.0 -0.6 1.3 -1.1 0.1 -1.2 1.4 -0.1 -0.9 -0.5 -1.1 1.4 0.6 -1.5 -0.2 -1.4 -0.1 -1.4 -0.7 0.6 0.2 0.3 0.8 -0.5 -1.1 -0.7 -0.1 -0.8 -0.7 1.2
Blood Red Count 0.1 1.1 9.9 2.5 0.1 -0.8 0.4 0.2 0.5 -1.2 -0.3 -1.3 0.7 0.0 -0.0 -0.5 0.4 0.3 1.4 -1.1 0.4 -0.7 -1.0 -0.5 -0.8 -1.5 -0.5 -1.7 0.8 0.4 0.8 0.1 -3.1
Blood White Count 0.0 0.3 1.0 1.0 0.9 -0.4 0.0 0.4 0.2 -0.5 0.8 0.5 0.9 0.4 -0.3 -0.9 -0.7 0.8 0.5 -0.0 -0.3 0.2 0.4 0.7 0.0 0.0 -0.3 0.6 0.8 1.0 -0.2 0.5 -0.5
Heel T-Score 0.2 2.0 8.2 2.9 1.2 -0.5 1.4 1.1 1.4 2.7 1.2 1.5 1.1 1.4 -2.3 -1.2 1.3 1.1 1.1 1.0 1.4 0.9 1.2 1.1 0.9 0.6 0.9 1.2 1.2 1.5 1.6 1.5 -1.2
BMI 0.5 2.8 5.9 -1.5 -1.9 1.0 -2.1 -1.0 -2.4 0.0 -1.5 -1.3 -1.9 -2.2 2.4 2.0 -2.0 -1.9 -2.0 -1.3 -2.0 -1.6 -0.9 -1.0 -1.1 -0.3 -1.5 -1.3 -2.1 -1.4 -1.7 -1.9 1.6
Height 0.8 15.3 114.5 -8.2 0.3 5.4 -0.3 0.3 0.0 3.7 1.2 3.3 -1.2 0.6 0.9 1.0 0.0 0.3 -3.5 5.5 -0.0 3.1 5.5 4.3 4.4 7.4 4.4 4.4 -2.0 -0.0 -0.5 0.5 10.7
Waist Hip Ratio (WHR) 2.3 10.4 18.7 3.1 3.7 -2.4 4.0 3.3 3.9 -1.5 3.4 3.0 3.9 3.8 -3.5 -3.8 3.9 3.3 4.2 1.1 3.8 3.6 1.2 2.7 0.3 -0.1 2.8 1.9 3.8 3.2 3.5 3.7 -4.3
Systolic Blood Pressure 2.3 11.6 19.8 0.1 4.0 1.2 3.4 2.3 3.4 1.7 3.4 3.7 3.9 3.8 -3.6 -3.6 2.7 4.2 1.9 4.3 3.1 4.3 4.1 4.5 3.6 3.5 3.9 3.8 3.7 3.6 2.7 4.1 0.7
Smoking Status 0.4 1.0 5.2 -0.6 -1.1 -0.0 -0.8 -0.4 -1.0 0.6 -0.4 -1.1 -0.9 -1.1 1.4 0.9 -0.7 -1.0 -0.6 -0.9 -0.8 -0.9 -1.5 -1.6 -0.1 -0.9 -2.3 -0.5 -0.7 -0.9 -1.4 -1.0 -0.3
Allergy or Eczema 0.2 0.6 7.1 0.6 0.2 -2.7 -0.2 -0.9 0.1 -1.1 -0.6 -0.1 -0.1 0.1 -0.3 0.0 -0.6 -0.3 0.3 -0.6 -0.3 -0.1 -0.9 -0.4 -1.3 -1.3 -1.1 0.5 -0.0 0.1 -0.5 -0.1 -0.9
Cardiovascular Disease 0.6 2.1 5.2 -0.4 1.6 0.7 1.1 1.1 1.2 0.6 1.4 1.6 1.5 1.5 -0.9 -1.6 0.7 1.7 0.8 2.0 0.9 1.7 2.1 2.3 1.8 1.9 1.8 1.7 1.3 1.5 0.9 1.6 1.1
Hypothyroidism (self reported) 0.7 1.5 6.2 -2.3 -1.2 1.5 -1.3 -1.3 -1.2 0.9 -1.1 -0.9 -1.2 -1.3 1.7 1.1 -1.4 -0.8 -1.6 0.3 -1.4 -0.9 0.1 0.1 1.1 0.5 -0.7 -0.3 -1.1 -0.9 -1.4 -1.0 2.5
Respiratory disease 0.8 1.8 4.1 0.2 -1.3 -1.4 -1.3 -0.7 -1.3 -1.8 -1.2 -1.5 -1.1 -1.5 1.1 1.2 -1.3 -1.3 -0.8 -1.9 -1.3 -1.5 -1.7 -1.6 -1.7 -1.5 -2.0 -1.0 -1.1 -0.6 -1.2 -1.2 -0.9
Type 2 Diabetes (T2D) (2018) 0.6 1.2 3.8 0.8 -1.0 -0.0 -0.7 -0.6 -0.5 -1.2 -0.9 -1.9 -0.6 -1.2 0.7 0.5 -0.9 -0.8 0.1 -1.3 -0.8 -1.6 -1.6 -1.7 -0.3 -1.7 -1.9 -1.3 -0.3 -0.9 -0.9 -1.0 -1.2
Lung FEV1/FVC ratio 0.2 1.1 10.9 1.6 -0.4 -1.2 0.8 -0.1 0.5 -0.7 -0.3 -1.5 0.2 0.1 -0.5 -0.1 1.0 -0.2 0.7 -0.8 0.9 -0.6 -1.1 -0.6 -0.3 -2.0 -0.7 -2.0 0.8 -0.2 1.0 0.1 -3.3
Lung FVC 1.2 6.1 36.5 3.6 1.9 -3.8 2.5 0.6 2.5 -4.0 1.1 0.4 2.4 2.3 -3.2 -2.2 2.6 1.6 3.3 -1.1 2.5 1.1 -1.7 -0.6 -1.8 -2.8 0.6 -0.3 2.7 1.0 2.1 1.9 -6.0
Neuroticism 0.2 0.4 2.1 1.4 0.7 -0.1 0.4 0.2 0.4 0.2 0.6 1.5 0.3 0.7 -0.0 -0.3 0.6 0.3 1.2 0.0 0.5 0.6 0.6 1.0 -0.6 0.4 1.1 0.5 -0.0 0.5 0.8 0.3 0.0
Chronotype (morning person) 4.5 10.5 20.8 2.3 4.1 -2.2 3.8 0.6 4.1 -0.2 3.1 3.6 4.0 4.0 -4.6 -4.0 3.7 3.7 3.7 2.5 3.8 3.9 1.9 2.8 0.6 1.0 3.5 2.3 4.0 2.9 3.5 3.6 -3.0
Hair Pigment 0.1 1.9 4.6 -1.7 -1.5 2.1 -1.8 -1.4 -1.6 1.0 -1.1 -1.7 -1.2 -1.8 1.2 1.5 -1.9 -1.0 -1.9 0.2 -1.8 -1.4 0.5 -0.3 0.7 0.9 -1.1 -1.3 -1.3 -0.6 -1.2 -1.2 2.0
Tanning 0.1 1.0 4.1 -1.6 -1.0 1.1 -1.1 -0.3 -1.1 -0.1 -0.6 -0.4 -1.2 -0.9 1.6 1.2 -0.9 -0.9 -1.7 0.3 -0.9 -0.6 -0.1 -0.8 0.3 0.8 -0.6 0.3 -1.2 -1.1 -1.1 -1.0 2.0
Hand grip strength (left) 0.3 0.8 5.2 0.4 0.1 -2.1 -0.3 -0.5 -0.3 -1.9 -0.6 1.0 -0.3 0.2 -0.2 0.1 -0.3 -0.6 0.3 -1.4 -0.3 -0.1 -0.8 0.5 -2.3 -1.7 0.3 -0.2 -0.6 -0.8 -0.3 -0.3 -0.5
Number of treatments/medications taken 0.7 1.3 2.4 -1.0 -1.5 0.9 -1.5 0.4 -1.2 0.6 -1.2 -1.3 -1.5 -1.6 1.5 1.4 -1.5 -1.2 -1.0 -0.0 -1.5 -1.4 -0.2 -0.3 0.4 0.1 -1.5 -0.7 -1.3 -0.5 -1.4 -1.2 1.5
Average weekly spirits intake 2.1 2.6 5.0 0.1 -1.7 -0.8 -1.7 -1.4 -1.9 -1.0 -2.0 -1.2 -1.6 -1.7 1.4 1.7 -1.6 -2.0 -1.1 -2.0 -1.5 -2.1 -2.0 -2.2 -1.7 -1.8 -2.0 -0.9 -1.6 -1.7 -1.7 -1.7 0.1
Sensitivity / hurt feelings 0.5 0.9 2.9 -0.5 -1.0 0.9 -1.2 -0.5 -1.2 0.3 -0.8 -0.4 -1.3 -1.1 1.3 1.3 -1.0 -1.2 -0.9 -0.4 -1.2 -1.0 -0.1 -0.3 -0.3 0.1 -0.8 -0.1 -1.4 -0.8 -1.0 -1.2 1.7
Frequency of depressed mood in last 2 weeks 0.8 1.1 3.3 1.8 1.0 -0.2 1.1 1.5 1.1 -0.4 1.6 0.9 1.0 1.1 -1.1 -0.8 1.2 0.9 1.5 0.1 1.0 0.9 0.5 0.7 -0.1 0.3 0.7 0.8 0.9 1.6 1.3 1.0 -1.2
Hearing difficulty/problems: Yes 2.5 3.8 5.6 -1.7 -2.3 -0.3 -2.1 -1.2 -2.3 -1.0 -2.1 -2.4 -2.2 -2.2 2.0 2.1 -2.0 -2.3 -1.5 -2.3 -2.1 -2.3 -1.9 -1.5 -1.7 -1.6 -2.0 -2.2 -2.2 -2.0 -1.9 -2.2 0.5
Relative age of first facial hair 0.5 1.1 2.2 -0.5 -1.2 0.7 -1.4 -0.9 -1.3 0.5 -1.1 -0.5 -1.3 -1.2 1.2 1.1 -1.5 -1.2 -0.9 -0.8 -1.4 -1.2 -0.4 -0.8 -0.7 -0.1 -1.0 -0.6 -1.4 -0.6 -1.2 -1.3 1.2
Other serious medical condition/disability diagnosed by doctor 2.6 3.4 7.1 -0.6 -2.0 -0.3 -2.1 -0.2 -2.1 -1.4 -2.1 -1.0 -2.4 -2.1 2.0 2.4 -1.8 -2.5 -1.8 -2.2 -2.0 -2.0 -1.6 -1.4 -2.4 -1.3 -1.2 -1.1 -2.7 -1.9 -1.7 -2.2 1.4
Ever used hormone-replacement therapy (HRT) 2.6 3.3 6.0 -1.3 -2.3 0.0 -2.0 -1.2 -2.0 -1.0 -1.9 -2.0 -2.5 -2.2 2.0 2.3 -1.8 -2.2 -1.7 -1.2 -1.7 -1.9 -1.7 -2.3 -1.1 -1.1 -2.3 -1.4 -2.2 -2.0 -1.8 -2.2 0.8
Ever had hysterectomy (womb removed) 0.7 0.8 2.3 1.3 0.8 -1.3 0.8 0.9 1.3 -0.6 0.8 0.4 0.8 0.9 -0.9 -1.0 0.9 0.7 1.5 0.4 0.9 0.7 0.6 0.6 -0.2 -0.3 0.4 -0.0 0.9 0.7 1.1 0.8 -1.5
Systolic blood pressure, automated reading 1.4 4.0 9.4 -0.2 1.8 1.9 1.5 1.6 1.7 2.4 1.9 1.7 1.6 1.9 -1.6 -1.4 1.2 2.1 0.4 3.0 1.5 2.1 3.1 2.8 3.0 3.0 1.9 2.3 1.5 2.2 1.4 1.9 1.7
Eye problems/disorders: Diabetes related eye disease 0.2 0.3 2.0 1.4 0.1 -0.6 0.3 0.4 0.5 -0.8 0.3 -0.2 0.3 0.1 -0.5 -0.2 0.4 0.1 0.6 -0.2 0.5 -0.1 -0.3 -0.5 0.5 -0.6 -0.6 0.5 0.4 0.1 0.3 0.4 -1.0
Angina 0.5 0.6 1.5 -0.7 -0.9 0.1 -0.9 -0.8 -0.8 0.1 -0.8 -0.4 -1.1 -0.7 0.9 0.9 -0.7 -1.1 -0.1 -0.9 -0.8 -0.7 -0.5 -0.6 -1.1 -0.4 -0.5 -0.8 -1.2 -1.0 -0.5 -1.1 0.5
Medication for hormone replacement therapy 0.8 0.9 5.0 -1.0 -0.6 -1.6 -0.5 -1.5 -0.3 -2.2 -1.1 -0.7 -0.6 -0.3 0.2 0.5 -0.5 -0.8 -0.3 -1.0 -0.4 -0.4 -1.4 -0.6 -1.2 -1.6 -0.6 -0.8 -0.5 -1.1 -0.8 -0.6 -0.5
Vitamin and mineral supplements 0.3 0.4 2.0 -0.6 0.5 0.7 0.3 -0.1 0.2 0.7 0.8 0.6 0.3 0.3 -0.4 -0.3 0.1 0.6 0.1 1.1 0.2 0.7 0.8 0.7 1.4 1.1 0.1 1.3 0.4 0.6 0.0 0.4 1.1
Supplements: Zinc 0.5 0.6 2.6 0.8 -0.6 -0.3 -0.3 -0.5 -0.4 -1.0 -0.6 -0.8 -0.5 -0.7 0.2 0.5 -0.0 -0.7 0.0 -1.2 -0.2 -0.7 -1.0 -0.8 -1.6 -1.1 -0.5 -1.2 -0.6 -0.4 0.1 -0.7 -1.2
Medication: Co-codamol 1.3 1.4 6.8 -0.9 -1.1 2.0 -1.5 -0.9 -1.0 0.6 -0.3 -0.6 -1.2 -1.0 1.5 1.3 -1.8 -0.9 -0.9 0.1 -1.7 -1.1 0.3 -1.0 0.9 1.2 -1.0 0.3 -1.3 -0.5 -1.5 -1.2 2.6
Medication: Metformin 0.5 0.7 2.6 0.2 -0.7 -0.7 -0.2 -0.3 -0.2 -1.5 -0.8 -1.3 -0.4 -0.8 0.2 0.3 -0.1 -0.6 0.0 -1.1 -0.1 -0.7 -1.5 -0.9 -0.8 -1.6 -0.9 -1.0 -0.2 -0.9 -0.4 -0.4 -1.3
Diabetes (father) 1.2 1.5 9.6 0.4 -0.2 -1.8 0.1 -1.0 -0.0 -3.1 -0.4 -1.2 0.3 -0.4 -0.6 -0.4 -0.0 -0.1 0.4 -1.2 0.0 -0.6 -1.9 -1.5 -1.3 -2.0 -1.6 -1.4 0.6 -0.4 -0.2 -0.1 -3.0
Diabetes (mother) 1.1 1.4 10.7 1.5 0.4 -0.8 0.9 -0.4 1.3 -2.4 0.4 -0.9 1.1 0.3 -1.0 -1.0 1.0 0.8 1.4 -1.1 0.9 0.1 -1.2 -1.2 -0.6 -1.7 -0.2 -1.1 1.3 0.4 0.7 0.7 -3.3
Severe depression (siblings) 1.1 1.3 6.0 0.3 0.6 2.3 0.5 1.2 0.4 1.7 1.3 0.7 0.5 0.4 -0.1 -0.3 0.5 0.9 0.2 1.5 0.4 0.6 2.0 1.2 1.7 2.4 1.2 0.7 0.4 1.3 0.9 0.6 1.4
Pack years adult smoking proportion 2.2 3.4 7.7 -2.8 -2.0 2.5 -2.2 -0.4 -2.2 0.5 -1.2 -1.8 -1.9 -2.3 2.8 1.9 -2.0 -1.5 -2.7 -0.5 -2.2 -1.6 -0.4 -1.3 0.2 0.6 -1.7 -1.3 -2.0 -1.5 -2.1 -1.8 2.5
Impedance of leg (right) 0.3 1.5 6.1 1.1 0.9 0.0 1.4 0.3 1.6 -0.9 1.7 -0.4 1.6 1.2 -1.1 -1.4 1.4 1.4 1.7 0.6 1.5 0.8 0.3 0.0 1.4 0.1 0.2 -0.6 1.9 1.1 1.3 1.2 -2.5
Leg fat-free mass (left) 0.8 4.1 25.5 -4.5 -1.5 1.8 -1.9 -0.9 -2.1 1.0 -1.5 0.2 -2.3 -1.8 1.8 2.1 -1.8 -1.7 -3.6 0.5 -1.9 -0.4 0.4 0.1 0.0 1.6 0.1 0.8 -2.7 -2.0 -2.1 -1.5 5.0
Trunk fat percentage 1.2 4.8 11.7 -3.4 -2.5 1.8 -2.5 -2.4 -2.5 -0.8 -1.9 -2.5 -2.4 -2.6 2.8 2.6 -2.4 -2.1 -2.4 -1.1 -2.5 -2.0 -1.1 -1.8 -0.3 -0.1 -1.8 -2.1 -2.4 -2.3 -2.3 -2.4 2.3
Hand grip strength (right) 0.3 0.7 4.7 0.3 -0.1 -1.7 -0.6 -0.7 -0.7 -1.9 -0.6 0.7 -0.6 -0.2 0.0 0.4 -0.9 -0.8 -0.0 -1.3 -0.7 -0.4 -0.7 0.1 -2.2 -1.4 -0.1 -0.4 -0.9 -0.8 -0.6 -0.6 -0.1
Townsend deprivation index at recruitment 1.4 2.0 3.7 0.5 1.6 -0.1 1.6 1.2 1.7 -0.0 1.5 1.4 1.5 1.5 -1.3 -1.7 1.5 1.6 1.4 1.6 1.4 1.8 1.1 1.6 1.1 1.0 1.3 1.9 1.5 1.7 1.2 1.7 -0.3
Current tobacco smoking 1.0 1.6 4.8 -1.2 -1.6 1.4 -1.2 -0.9 -1.0 1.0 -0.5 -2.0 -1.2 -1.4 1.9 1.2 -1.1 -1.0 -1.0 -0.7 -1.2 -1.4 -1.3 -1.8 0.5 -0.3 -2.2 -1.1 -0.9 -0.8 -1.5 -1.3 0.3
Average weekly fortified wine intake 0.4 0.5 1.5 0.7 -0.4 0.3 -0.8 0.2 -0.7 0.6 -0.1 0.3 -0.7 -0.5 1.2 0.6 -0.7 -0.7 -0.5 -1.2 -0.8 -0.7 -0.5 -0.9 -1.2 -0.3 -0.3 0.2 -0.9 -0.3 -0.7 -0.8 0.6
Maternal smoking around birth 1.3 1.8 3.5 -1.9 -1.6 0.0 -1.4 -1.6 -1.1 -1.1 -1.0 -1.1 -1.6 -1.3 1.8 1.6 -1.5 -1.6 -0.9 -1.3 -1.4 -1.3 -1.4 -1.4 -0.9 -0.6 -1.4 -1.1 -1.5 -1.5 -1.7 -1.5 0.7
Fed-up feelings 0.4 0.8 2.6 -0.4 -0.9 0.9 -1.1 0.1 -1.1 0.7 -0.6 -0.2 -1.1 -0.9 1.6 1.1 -1.3 -1.0 -0.7 -0.1 -1.1 -0.8 0.1 -0.4 0.1 0.5 -0.5 0.0 -1.2 -0.7 -0.9 -0.9 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 3.1 0.4 1.1 0.8 1.0 0.9 1.1 0.8 1.8 0.7 1.2 1.0 -0.6 -1.1 1.0 1.3 1.2 1.1 0.9 1.2 1.0 0.7 1.2 1.4 0.8 0.9 1.1 1.3 1.0 1.1 -0.2
Relative age voice broke 0.0 0.1 1.1 -0.3 0.0 -0.0 0.0 0.2 0.4 1.0 -0.2 0.0 0.1 -0.0 0.0 -0.2 0.1 0.1 0.1 0.1 0.0 0.1 -0.0 0.3 0.1 -0.0 -0.0 0.1 0.1 0.3 -0.1 0.1 0.1
Taking other prescription medications 0.4 0.5 1.5 -0.7 -1.0 1.2 -0.9 0.1 -0.8 0.2 -0.4 -1.0 -0.7 -1.2 1.1 0.8 -0.9 -0.5 -0.8 -0.3 -0.9 -0.9 -0.1 -0.5 0.3 0.5 -0.7 -0.7 -0.7 -0.0 -0.6 -0.7 0.8
Age when periods started (menarche) 0.5 1.1 2.2 -1.3 -1.1 0.3 -1.2 -0.8 -1.4 -1.2 -1.0 -0.7 -1.2 -1.1 1.0 1.3 -1.2 -1.2 -1.2 -1.0 -1.2 -1.1 -1.0 -1.1 -0.6 -0.5 -1.1 -0.2 -1.2 -0.8 -1.5 -1.2 1.0
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 3.4 -0.6 0.8 0.5 0.6 0.8 0.9 0.4 1.1 0.2 0.9 0.5 -0.5 -0.9 0.6 1.1 0.4 1.6 0.7 1.0 1.2 0.9 1.8 1.3 0.5 0.5 1.0 0.6 0.3 0.9 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.3 0.5 0.0 -0.8 0.2 -0.4 0.2 0.1 -0.2 -0.6 0.2 0.0 -0.8 -0.2 0.2 0.1 -0.1 -0.2 0.3 0.0 -0.2 0.1 -0.2 -0.9 -0.2 -0.6 0.3 -0.1 0.3 0.3 -1.1
Tinnitus: Yes, but not now, but have in the past 2.5 2.7 6.4 1.9 1.5 0.7 1.7 2.5 1.6 1.0 2.2 1.3 1.7 1.6 -1.1 -1.5 1.6 1.7 1.7 1.6 1.7 1.5 1.7 1.3 1.6 1.7 1.4 1.5 1.6 2.1 1.8 1.8 -0.7
Qualifications: CSEs or equivalent 0.2 0.3 1.0 -0.4 -0.6 -0.0 -0.2 -0.8 -0.4 -0.7 -0.7 -1.0 -0.4 -0.6 0.5 0.6 -0.1 -0.5 -0.4 -0.3 -0.3 -0.6 -0.6 -0.1 0.3 -0.6 -0.8 -0.8 -0.2 -0.6 -0.3 -0.4 -0.3
Serious illness, injury or assault to yourself 0.4 0.4 1.1 -0.7 -0.5 -0.8 -0.8 0.1 -0.6 -0.6 -0.6 -0.2 -0.9 -0.6 0.5 0.8 -0.8 -0.7 -0.7 -0.2 -0.9 -0.5 -0.4 -0.5 -0.5 -0.5 -1.1 0.4 -0.8 -0.4 -1.0 -0.6 0.8
High blood pressure 1.0 2.7 6.2 -0.7 1.8 0.9 1.4 1.0 1.5 1.1 1.3 1.7 1.5 1.9 -1.4 -1.5 1.1 1.9 0.8 2.5 1.3 2.2 2.1 2.4 1.9 2.2 2.1 2.1 1.4 1.4 1.1 1.8 1.3
Hayfever, allergic rhinitis or eczema 0.2 0.5 6.0 0.7 0.0 -2.4 -0.4 -0.8 -0.2 -0.7 -0.6 0.1 -0.2 -0.2 -0.1 0.2 -0.7 -0.5 0.1 -0.6 -0.4 -0.2 -0.7 -0.5 -1.2 -1.1 -1.2 0.9 -0.2 0.1 -0.6 -0.3 -0.4
Multivitamins +/- minerals 0.3 0.4 1.8 -0.9 -0.6 0.4 -0.7 -0.2 -0.7 -1.0 -0.6 -1.0 -0.4 -0.6 0.9 0.4 -0.6 -0.5 -0.9 -0.5 -0.6 -0.7 -0.4 -0.5 -0.4 -0.2 -0.2 -1.3 -0.4 -0.7 -0.5 -0.5 0.0
Stomach or abdominal pain in last month 0.4 0.5 3.9 -0.9 -0.4 -0.4 -0.4 -2.0 -0.1 -1.4 -0.2 -1.0 -0.1 -0.5 -0.0 0.1 -0.5 -0.3 -0.4 -0.8 -0.4 -0.4 -1.0 -0.9 -0.4 -0.7 -0.6 -1.1 -0.1 -0.8 -0.7 -0.4 -0.6
Supplements: Glucosamine 1.3 1.7 3.0 -0.4 -1.2 -1.4 -1.4 -0.5 -1.4 -0.4 -1.5 -0.3 -1.7 -1.3 1.4 1.5 -1.2 -1.7 -1.5 -1.3 -1.4 -1.2 -1.2 -1.1 -1.7 -1.1 -1.6 -0.2 -1.7 -1.1 -1.5 -1.5 0.7
Diverticular disease/diverticulitis (self-reported) 2.7 3.3 5.0 1.1 1.9 0.5 1.9 1.0 2.0 1.4 2.2 1.3 2.1 1.8 -1.9 -2.2 1.9 2.2 2.1 2.0 2.0 1.9 2.0 1.9 2.0 1.7 2.1 0.6 2.1 1.5 2.2 1.9 -0.9
Medication: Atenolol 0.5 0.7 1.7 -0.6 0.6 0.6 0.9 -0.2 1.3 -0.4 0.8 -0.2 0.8 0.9 -1.0 -0.8 0.8 1.0 1.1 1.0 0.8 1.1 0.7 1.0 1.0 0.5 0.7 -0.6 1.0 0.2 0.8 0.8 -0.8
Medication: Levothyroxine sodium 0.3 0.5 2.8 -0.9 -0.6 0.2 -0.8 -1.5 -0.6 0.7 -1.0 -0.2 -0.8 -0.7 0.8 0.7 -0.8 -0.6 -0.7 0.2 -0.8 -0.5 0.1 0.1 0.4 -0.1 -0.4 0.2 -0.8 -0.7 -0.8 -0.7 1.7
Sitting height 0.7 5.0 33.3 -5.8 -1.8 2.2 -2.2 -3.2 -2.0 0.3 -1.3 -0.8 -2.1 -1.9 1.8 1.9 -2.2 -1.5 -3.7 0.4 -2.2 -0.5 -0.0 -0.4 0.6 1.5 -0.4 -0.4 -2.4 -2.5 -2.5 -1.8 4.7
Chronic bronchitis/emphysema (father) 1.3 1.5 2.4 1.5 1.4 0.7 1.3 1.1 1.4 1.4 1.4 1.1 1.4 1.2 -1.0 -1.0 1.2 1.4 1.2 1.3 1.2 1.2 1.3 1.0 1.0 1.2 1.3 1.0 1.4 1.6 1.3 1.3 -0.4
High blood pressure (mother) 0.5 0.7 2.7 -0.9 0.7 1.2 0.5 -0.1 0.3 0.4 0.5 0.5 0.8 0.5 -0.6 -0.7 0.2 1.0 0.1 1.2 0.4 0.8 0.9 0.9 1.6 1.3 0.6 1.2 0.8 0.9 0.0 0.7 1.1
Body mass index (BMI) 0.7 3.2 5.5 -2.3 -2.1 1.4 -2.1 -1.6 -2.2 0.1 -1.7 -1.8 -2.1 -2.2 2.3 2.2 -2.1 -1.9 -2.3 -0.7 -2.1 -1.7 -0.8 -1.3 -0.3 0.1 -1.6 -1.2 -2.2 -1.7 -1.9 -2.0 2.1
Impedance of leg (left) 0.3 1.3 6.1 1.4 0.8 -0.5 1.2 -0.1 1.4 -1.4 1.4 -0.4 1.4 1.2 -1.1 -1.2 1.2 1.2 1.8 0.2 1.3 0.6 0.3 0.2 0.9 -0.3 0.3 -0.8 1.7 1.0 1.3 1.0 -2.5
Leg predicted mass (left) 0.8 4.0 25.0 -4.5 -1.4 1.7 -1.9 -0.9 -2.0 0.9 -1.4 0.2 -2.2 -1.7 1.8 2.0 -1.8 -1.7 -3.5 0.6 -1.9 -0.3 0.4 0.1 0.1 1.7 0.1 0.9 -2.6 -1.9 -2.1 -1.5 5.0
Trunk fat mass 0.9 4.0 15.5 -3.9 -2.1 2.1 -2.2 -1.9 -2.2 -0.0 -1.5 -1.4 -2.3 -2.2 2.5 2.4 -2.1 -1.8 -2.7 -0.2 -2.2 -1.2 -0.2 -0.9 0.2 0.9 -0.9 -0.9 -2.4 -2.0 -2.0 -2.0 3.6
Waist circumference 0.5 1.9 9.5 -2.8 -1.3 1.4 -1.4 -0.6 -1.5 0.1 -1.0 -0.3 -1.7 -1.3 1.9 1.7 -1.3 -1.3 -2.0 0.2 -1.3 -0.4 0.2 0.0 0.2 1.1 -0.3 0.2 -1.9 -1.2 -1.3 -1.2 3.1
Number of incorrect matches in round 1.6 2.7 5.9 1.6 1.9 -2.4 1.8 0.9 1.8 -1.7 1.1 1.9 1.8 2.0 -2.2 -1.8 1.7 1.4 2.0 0.6 1.7 1.8 0.7 1.8 -0.5 -0.7 1.5 1.2 1.7 1.3 1.7 1.8 -1.8
Past tobacco smoking 0.1 0.1 0.8 -0.0 -0.3 0.9 -0.3 -0.2 -0.4 0.0 -0.3 -0.5 -0.1 -0.3 0.2 0.2 -0.3 0.1 0.0 -0.1 -0.3 -0.5 0.3 -0.1 0.1 0.3 0.3 -0.8 -0.2 0.0 0.0 -0.2 0.3
Alcohol usually taken with meals 0.9 1.5 4.6 0.6 1.3 -0.1 1.1 1.5 1.1 2.0 1.0 1.1 1.2 1.1 -1.0 -1.1 1.0 1.3 0.7 1.5 1.0 1.3 1.6 2.2 1.2 0.9 1.4 0.9 1.2 1.5 1.2 1.3 0.2
Nervous feelings 0.2 0.4 1.5 0.7 0.7 -0.1 0.6 -0.7 0.5 -1.2 0.5 0.7 0.8 0.6 -0.7 -0.7 0.7 0.7 1.1 0.1 0.6 0.6 -0.1 -0.0 -0.2 -0.1 0.3 0.1 0.7 0.2 0.4 0.6 -1.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 1.1 0.1 0.0 0.3 0.5 0.3 0.7 -0.8 0.7 -0.6 0.3 0.2 -0.3 -0.1 0.6 0.3 0.8 -0.0 0.6 0.3 -0.1 0.3 0.4 -0.0 -0.0 -0.5 0.4 0.6 0.6 0.4 -1.0
Hearing difficulty/problems with background noise 3.2 5.1 8.8 -0.7 -2.5 -1.2 -2.3 -1.3 -2.4 -1.6 -2.4 -2.4 -2.4 -2.4 2.4 2.3 -2.1 -2.7 -1.4 -3.0 -2.3 -2.7 -2.6 -2.3 -2.5 -2.7 -2.7 -2.6 -2.4 -2.3 -2.1 -2.5 -0.3
Hair/balding pattern: Pattern 2 0.4 0.6 1.7 -0.4 -0.6 -0.8 -0.5 -0.9 -0.5 -1.2 -0.9 -0.4 -0.6 -0.5 0.5 0.7 -0.4 -0.8 -0.4 -1.3 -0.4 -0.5 -1.2 -0.4 -1.2 -1.3 -0.3 -0.8 -0.6 -0.9 -0.4 -0.5 -0.6
Had menopause 0.3 0.3 2.9 1.0 -0.2 0.9 -0.1 1.6 0.0 1.7 0.2 0.3 -0.5 -0.0 0.5 0.4 0.2 -0.3 0.2 0.2 0.1 -0.2 0.5 0.0 0.3 0.7 -0.1 0.6 -0.5 0.6 0.2 -0.2 0.6
Had other major operations 2.3 2.8 4.6 -1.9 -2.0 0.3 -1.9 -1.7 -1.5 -0.2 -1.8 -1.7 -2.1 -1.9 1.8 2.0 -1.8 -2.0 -1.6 -1.2 -1.9 -1.8 -1.2 -1.3 -0.9 -1.0 -1.9 -1.4 -2.0 -1.6 -1.9 -2.1 1.4
Forced vital capacity (FVC) 1.1 4.4 10.6 1.0 2.5 -1.5 2.5 1.2 2.3 -1.9 2.1 2.4 2.5 2.6 -3.2 -2.5 2.5 2.2 2.0 1.4 2.5 2.5 0.9 1.7 0.5 0.4 2.3 1.9 2.4 1.6 2.1 2.6 -1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.1 0.9 0.6 -0.2 0.2 0.3 -0.2 0.3 0.5 0.0 -0.7 0.0 -0.1 -0.6 0.0 0.5 0.0 0.2 0.0 0.5 -0.0 0.1 0.0 0.3 -0.2 -0.1 -0.8 0.2 0.1 0.6 0.2 -1.0
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.7 -0.0 0.0 0.0 -0.6 -0.5 -0.3 0.7 0.0 0.0 -0.1 -0.2 0.5 0.1 -0.8 0.0 -0.1 -0.3 -0.7 -0.4 -0.1 -0.3 -0.2 0.0 -0.5 -0.3 -0.1 -0.2 -0.6 -0.3 0.1
Qualifications: None of the above 2.5 5.4 22.6 -0.4 1.2 3.7 1.6 1.2 1.9 2.5 2.5 0.9 1.3 1.6 -1.0 -1.4 1.6 2.1 1.2 4.2 1.7 2.0 3.6 1.9 4.8 4.5 1.7 2.2 1.6 2.3 1.8 1.7 2.1
Financial difficulties in last 2 years 0.5 0.7 3.4 -1.3 -0.7 1.4 -0.8 -0.5 -0.9 0.5 0.2 -0.8 -0.8 -0.9 0.9 0.8 -0.9 -0.4 -0.7 0.7 -0.9 -0.3 0.3 0.1 1.1 1.2 -1.0 0.5 -0.8 0.1 -0.8 -0.6 1.9
Mouth/teeth dental problems 0.7 1.1 5.5 2.3 0.8 -1.6 1.1 -0.3 0.8 -0.8 0.1 0.9 0.7 1.1 -1.7 -0.9 1.2 0.4 1.5 -0.5 1.2 0.4 -0.2 0.2 -1.0 -1.1 1.1 -0.0 0.8 0.3 1.4 0.6 -2.1
Heart attack 0.2 0.3 1.5 -1.2 -0.3 0.8 0.2 0.9 0.3 0.3 0.3 -1.1 0.0 -0.3 0.4 -0.2 0.2 0.2 0.2 0.6 0.2 0.1 0.1 0.1 1.2 0.4 -0.4 -0.4 0.3 -0.0 0.2 0.2 -0.1
Allergy 0.3 0.7 7.4 -0.7 -0.1 2.7 0.3 0.5 0.1 0.8 0.5 0.1 -0.0 0.1 0.3 0.0 0.6 0.3 -0.1 0.8 0.4 0.2 1.1 0.5 1.2 1.5 1.4 -0.8 -0.1 -0.2 0.6 0.1 1.0
Pain all over the body in last month 0.2 0.2 1.3 0.2 -0.1 -0.6 -0.5 0.0 -0.6 -0.2 -0.4 0.6 -0.5 -0.3 0.3 0.5 -0.5 -0.6 -0.1 -0.3 -0.5 -0.2 -0.2 -0.4 -1.1 -0.0 -0.4 0.7 -0.7 -0.1 -0.4 -0.4 0.5
Diabetes (self-reported) 0.9 1.4 4.7 0.4 -1.0 -0.9 -0.6 -0.7 -0.4 -1.8 -1.0 -1.8 -0.6 -1.1 0.6 0.4 -0.5 -0.9 -0.1 -1.6 -0.6 -1.3 -2.1 -1.8 -0.9 -2.2 -1.8 -1.4 -0.3 -1.2 -0.8 -0.8 -1.7
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.5 -0.6 -0.3 0.2 -0.3 -0.7 -0.1 0.6 -0.1 -0.6 -0.3 -0.2 0.3 0.1 -0.5 -0.1 -0.6 0.2 -0.4 -0.3 0.1 -0.5 0.3 0.1 -0.4 -0.3 -0.1 -0.2 -0.3 -0.3 0.2
Medication: Ramipril 1.1 1.4 2.5 0.3 1.3 -0.7 1.4 1.3 1.4 -0.2 0.9 0.8 1.3 1.3 -1.0 -1.5 1.4 1.3 1.3 1.5 1.5 1.6 1.0 1.5 1.0 0.4 1.1 1.2 1.4 1.1 1.4 1.5 -0.7
Medication: Simvastatin 1.1 1.7 3.2 0.5 1.4 0.5 1.5 1.2 1.6 0.4 1.6 1.1 1.5 1.4 -1.1 -1.5 1.4 1.5 1.8 1.0 1.4 1.6 1.1 1.4 0.8 1.1 1.7 0.6 1.4 1.1 1.6 1.6 -0.8
Fluid intelligence score 1.4 3.0 6.0 -1.3 -1.5 -1.1 -1.9 -1.8 -1.9 -1.1 -2.5 -0.4 -2.0 -1.6 1.5 1.9 -1.8 -2.1 -1.7 -1.8 -1.9 -1.6 -1.5 -1.6 -2.0 -1.6 -1.1 -0.3 -2.2 -2.0 -2.2 -1.9 1.9
Illnesses of siblings 3.5 4.9 9.5 -0.4 -2.2 -0.9 -2.5 -1.8 -2.8 -1.2 -2.5 -0.8 -2.8 -2.4 2.5 2.9 -2.3 -3.0 -1.8 -2.5 -2.4 -2.4 -1.8 -2.1 -2.7 -1.7 -1.7 -1.0 -3.1 -2.5 -2.3 -2.6 1.8
Neuroticism score 0.3 0.6 1.6 1.0 0.8 0.3 0.7 0.3 0.7 -0.2 0.9 1.0 0.6 0.8 -0.4 -0.7 0.8 0.6 1.3 0.6 0.8 0.8 0.9 1.2 0.2 0.6 1.0 0.4 0.5 0.7 1.0 0.7 -0.2
Weight 0.7 3.5 21.5 -4.1 -1.4 2.0 -1.8 -1.1 -1.9 0.8 -1.1 -0.1 -2.0 -1.6 2.0 2.0 -1.7 -1.5 -3.0 0.8 -1.7 -0.4 0.6 0.0 0.6 1.8 -0.1 0.7 -2.3 -1.6 -1.8 -1.4 4.6
Impedance of arm (right) 0.1 0.7 4.7 -0.0 0.3 -1.2 0.4 -0.7 0.3 -1.6 0.2 -0.9 0.9 0.3 -0.4 -0.7 0.3 0.6 0.9 -0.8 0.3 0.1 -0.8 -0.5 -0.3 -1.3 -0.4 -1.3 1.1 -0.1 0.1 0.4 -2.2
Arm fat percentage (right) 0.8 3.3 6.5 -2.5 -2.1 1.2 -2.0 -2.1 -2.1 -0.4 -1.7 -2.3 -1.9 -2.2 2.4 2.0 -2.0 -1.7 -2.0 -1.1 -2.0 -1.6 -1.2 -1.6 -0.5 -0.4 -1.6 -2.0 -1.9 -2.0 -1.8 -2.0 1.4
Trunk fat-free mass 0.6 3.5 29.3 -3.5 0.2 1.8 -0.3 0.6 -0.4 2.2 0.3 2.4 -0.9 0.2 0.4 0.6 -0.2 -0.3 -2.5 2.3 -0.3 1.4 2.1 1.9 1.2 3.2 2.1 3.0 -1.4 -0.4 -0.5 0.1 5.4
Hip circumference 2.5 10.7 38.8 -5.2 -3.4 2.6 -3.8 -2.5 -3.9 1.0 -3.0 -1.8 -4.1 -3.6 4.0 4.0 -3.7 -3.3 -4.8 -0.4 -3.8 -2.4 -0.4 -1.3 -0.2 1.2 -1.7 -0.6 -4.4 -3.1 -3.6 -3.4 6.2
Time employed in main current job 0.5 0.5 1.9 -0.8 0.4 0.5 0.9 0.1 0.6 1.2 0.6 0.4 0.4 0.5 -0.7 -0.5 1.2 0.7 0.1 1.4 1.0 1.1 0.7 0.4 1.2 1.1 0.9 0.2 0.5 0.0 0.7 0.6 0.2
Alcohol intake versus 10 years previously 1.3 1.9 3.8 0.9 1.3 0.1 1.9 1.1 1.9 -0.2 1.6 0.6 1.6 1.5 -1.9 -1.5 1.9 1.6 1.5 1.2 1.9 1.5 0.3 0.4 1.3 0.5 0.7 1.2 1.9 1.4 1.5 1.6 -1.6
Father’s age at death 0.7 0.9 4.8 2.2 0.1 -2.1 0.2 0.5 -0.1 0.2 -0.7 -0.0 0.1 -0.1 -0.3 -0.3 0.4 -0.4 0.4 -1.3 0.3 -0.5 -1.4 -1.1 -1.5 -2.1 -0.7 -0.1 0.2 -0.4 0.2 -0.1 -2.0
Worrier / anxious feelings 2.7 5.1 9.1 1.8 2.6 -0.7 2.8 0.7 2.8 -0.7 2.2 2.1 2.6 2.9 -2.9 -2.7 2.9 2.4 3.0 1.7 3.0 2.7 1.1 1.9 0.6 0.5 2.3 1.3 2.7 1.8 2.8 2.5 -2.6
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 3.6 -0.6 -0.3 1.9 -0.1 0.1 -0.1 0.6 0.6 -0.3 -0.2 -0.2 0.5 0.4 -0.1 -0.0 -0.2 0.4 -0.2 -0.1 0.9 0.1 0.9 1.5 0.5 -0.1 -0.4 0.3 0.4 -0.2 1.1
Falls in the last year 0.8 1.1 3.7 -1.7 -1.1 1.4 -1.1 -0.2 -1.1 1.0 -0.6 -1.0 -1.2 -1.3 1.6 1.3 -1.3 -0.7 -1.4 0.4 -1.2 -0.6 0.2 -0.8 0.6 0.8 -1.0 -0.2 -1.2 -0.6 -1.1 -0.8 1.9
Hair/balding pattern: Pattern 3 1.8 2.6 5.5 1.1 1.6 0.8 1.8 2.4 1.8 1.3 1.8 1.4 1.6 1.7 -1.4 -1.8 2.1 1.8 1.2 1.9 2.0 1.9 1.2 1.1 1.8 1.4 1.6 2.0 1.7 1.6 1.4 1.8 -0.3
Number of live births 0.1 0.1 0.6 -0.4 -0.5 0.7 -0.4 -0.8 -0.1 -0.5 -0.3 -0.6 -0.4 -0.4 0.2 0.4 -0.2 -0.3 -0.2 -0.1 -0.3 -0.3 -0.0 -0.0 0.2 0.3 -0.5 -0.5 -0.4 0.1 -0.3 -0.4 0.2
Forced expiratory volume in 1-second (FEV1) 0.9 3.1 8.8 1.4 1.9 -2.1 2.2 0.7 1.9 -2.5 1.4 1.4 2.0 2.0 -3.0 -2.1 2.0 1.6 1.8 0.5 2.1 1.7 -0.0 1.1 -0.3 -0.9 1.4 0.7 2.2 1.0 1.8 2.0 -2.9
Pulse rate 1.9 3.2 6.2 -1.4 -1.9 0.0 -1.8 -2.1 -1.7 -1.6 -1.6 -2.5 -1.5 -2.0 1.7 1.8 -1.9 -1.6 -1.9 -1.9 -1.8 -2.0 -2.0 -2.2 -1.2 -1.6 -2.1 -2.4 -1.4 -1.7 -1.9 -1.8 -0.2
Happiness 0.7 0.9 2.5 -1.6 -1.1 1.1 -1.0 -0.8 -1.1 0.3 -0.6 -1.2 -0.9 -1.2 1.6 0.9 -1.0 -0.7 -1.1 -0.5 -1.1 -0.8 -0.6 -0.5 0.2 0.1 -0.8 -1.3 -0.9 -0.9 -1.1 -0.9 0.7
Noisy workplace 0.4 0.5 1.3 -0.5 -1.0 0.7 -0.8 -0.7 -1.0 -0.9 -0.6 -0.6 -1.1 -1.0 0.8 1.1 -0.7 -0.9 -0.8 -0.1 -0.7 -0.7 0.2 0.3 0.2 0.3 -0.4 -0.7 -1.1 -0.6 -0.3 -0.7 1.0
Qualifications: A levels/AS levels or equivalent 1.3 2.8 9.3 -0.1 -1.2 -1.5 -1.5 -1.5 -1.8 -0.9 -2.0 -1.1 -1.2 -1.5 1.1 1.3 -1.6 -1.6 -0.9 -2.9 -1.6 -1.8 -2.4 -1.7 -3.0 -2.5 -1.4 -1.9 -1.3 -1.5 -1.6 -1.6 -1.0
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.7 1.0 0.5 1.3 1.0 0.6 1.1 -0.0 1.0 0.1 0.8 0.8 -0.8 -0.7 1.3 0.8 1.1 0.6 1.1 0.5 0.5 0.1 0.8 0.9 0.8 0.1 0.9 1.1 1.1 0.7 -0.9
Mouth/teeth dental problems: Dentures 2.8 4.8 14.4 -2.8 -2.1 2.3 -2.7 -0.3 -2.4 1.9 -1.2 -1.5 -2.4 -2.5 3.5 2.3 -2.9 -1.9 -2.8 -0.5 -2.8 -1.8 -0.4 -1.7 0.2 1.0 -2.1 -0.2 -2.5 -1.6 -2.8 -2.2 3.8
Asthma 0.5 0.9 4.7 0.6 -0.3 -2.2 -0.3 -0.7 -0.2 -2.1 -0.4 -0.7 -0.1 -0.5 -0.1 0.2 -0.3 -0.5 0.4 -1.4 -0.2 -0.5 -1.5 -0.8 -1.4 -1.7 -1.4 -0.3 -0.0 0.0 -0.3 -0.3 -1.7
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.1 -0.0 -0.8 -1.5 -0.8 -1.0 -0.8 -0.1 -0.8 -0.3 -1.1 -0.7 0.7 1.1 -0.9 -1.2 -0.5 -0.9 -0.8 -0.7 -0.9 -0.6 -1.0 -1.0 -1.3 0.4 -1.1 -0.7 -0.8 -1.0 0.5
Medication: Cholesterol lowering 0.1 0.1 0.3 -0.4 -0.4 0.3 -0.3 0.0 -0.2 -0.4 -0.4 -0.3 -0.3 -0.4 0.5 0.4 -0.3 -0.3 0.1 -0.3 -0.2 -0.2 -0.3 0.1 -0.2 -0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.1 0.2
Depression (self-reported) 0.5 0.6 1.4 0.5 0.9 -0.4 0.9 0.6 0.9 0.5 0.7 0.9 1.0 1.0 -1.2 -1.0 0.8 0.8 0.6 0.5 0.9 0.9 0.1 0.4 0.2 0.2 0.7 0.8 1.0 0.6 0.6 1.0 -0.8
Medication: Lansoprazole 0.1 0.2 1.5 -0.6 0.0 -0.3 -0.2 0.1 -0.3 -0.2 0.0 0.6 -0.3 0.0 0.2 0.2 -0.2 -0.2 -0.1 0.4 -0.1 0.3 -0.2 0.2 0.1 -0.0 -0.6 1.2 -0.3 -0.1 -0.7 -0.0 0.9
Prospective memory result 0.1 0.1 1.1 -0.1 0.1 0.2 0.1 0.3 0.1 1.0 0.3 0.2 0.2 0.0 -0.3 -0.1 0.1 0.2 0.2 0.2 0.0 0.2 0.1 0.3 0.1 0.2 -0.1 0.0 0.2 0.3 0.1 0.1 -0.2
Lung cancer (father) 0.7 0.9 1.9 -0.7 -1.0 -0.3 -1.1 -0.7 -1.2 0.6 -1.0 -0.5 -1.3 -1.0 0.8 1.0 -1.0 -1.3 -1.0 -0.5 -1.1 -0.9 -0.4 -0.6 -0.8 -0.4 -1.0 -0.4 -1.4 -0.9 -0.9 -1.2 1.0
Illnesses of mother 0.2 0.2 1.1 1.1 0.0 -0.7 -0.3 0.9 -0.6 0.3 -0.1 0.3 -0.2 -0.3 0.2 0.2 -0.4 -0.3 -0.1 -0.3 -0.3 -0.3 -0.0 0.2 -0.7 -0.5 -0.7 0.4 -0.3 0.4 -0.0 -0.2 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.2 13.0 1.6 2.2 -3.2 2.3 0.2 2.1 -3.5 1.3 1.6 2.2 2.3 -3.0 -2.3 2.2 1.7 2.4 0.4 2.3 1.9 -0.3 1.0 -0.9 -1.5 1.3 0.7 2.4 0.9 1.8 2.1 -3.6
Pulse wave Arterial Stiffness index 0.1 0.1 0.4 -0.0 -0.4 0.2 -0.3 0.0 -0.4 0.4 -0.3 -0.1 -0.5 -0.5 0.1 0.5 -0.2 -0.4 -0.6 -0.0 -0.2 -0.1 -0.2 -0.4 -0.3 -0.1 -0.2 0.2 -0.5 -0.3 -0.2 -0.4 0.5
Impedance of arm (left) 0.1 0.5 3.5 0.0 0.1 -1.2 0.2 -0.6 0.2 -1.5 -0.1 -0.9 0.6 0.1 -0.3 -0.4 0.1 0.3 0.8 -0.8 0.1 -0.2 -0.8 -0.6 -0.5 -1.4 -0.5 -1.3 0.8 -0.2 -0.0 0.2 -1.9
Arm fat mass (right) 0.9 3.7 10.4 -3.2 -2.1 1.9 -2.3 -1.7 -2.3 0.3 -1.6 -1.5 -2.3 -2.2 2.5 2.3 -2.2 -1.9 -2.6 -0.4 -2.2 -1.4 -0.4 -1.1 -0.0 0.7 -1.2 -0.9 -2.4 -1.9 -2.1 -2.1 3.2
Trunk predicted mass 0.6 3.5 28.7 -3.5 0.3 1.8 -0.3 0.6 -0.4 2.1 0.3 2.4 -0.8 0.2 0.3 0.6 -0.1 -0.2 -2.5 2.3 -0.2 1.5 2.1 1.9 1.2 3.2 2.1 3.0 -1.4 -0.4 -0.5 0.1 5.4
Standing height 0.5 5.1 34.6 -4.2 1.1 1.6 0.4 0.8 0.3 1.8 1.1 3.4 -0.2 1.1 -0.4 -0.0 0.5 0.5 -1.9 3.1 0.5 2.6 2.9 2.6 1.8 3.8 3.1 3.8 -0.8 -0.1 -0.1 0.9 5.9
Length of working week for main job 1.6 1.8 3.4 -1.7 -1.4 -0.7 -1.5 -1.8 -1.6 -0.7 -1.3 -1.1 -1.5 -1.5 1.1 1.5 -1.5 -1.6 -1.4 -0.9 -1.5 -1.4 -0.9 -0.6 -0.6 -1.0 -1.6 -1.4 -1.4 -1.6 -1.6 -1.5 1.0
Exposure to tobacco smoke at home 4.0 4.5 8.2 -0.1 2.1 0.6 2.5 1.8 2.5 1.3 2.4 1.4 2.2 2.3 -2.0 -2.3 2.5 2.5 1.8 2.6 2.6 2.9 2.0 2.6 2.4 2.1 2.6 1.4 2.3 1.7 2.2 2.5 -0.5
Breastfed as a baby 2.0 2.5 9.4 0.8 -0.9 -2.9 -0.9 -1.7 -0.8 -1.7 -2.3 0.0 -1.4 -0.5 0.2 1.3 -0.7 -2.0 -0.4 -2.4 -0.8 -1.1 -2.3 -1.5 -3.1 -2.9 -1.1 -0.2 -1.5 -1.6 -1.2 -1.3 -0.8
Tense / ‘highly strung’ 0.3 0.5 1.4 0.8 0.8 0.1 0.8 0.2 1.0 -0.1 1.1 0.5 1.0 0.6 -0.7 -0.8 0.9 0.9 1.0 0.2 0.8 0.8 0.1 0.3 0.1 0.0 0.5 -0.1 0.9 0.6 0.7 0.8 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 2.1 0.9 1.3 -0.7 1.2 0.6 1.4 -0.3 1.2 0.9 1.2 1.1 -1.1 -1.4 1.1 1.2 1.2 0.6 1.1 1.2 0.0 0.7 0.2 -0.0 0.5 1.0 1.3 1.0 0.7 1.2 -1.3
Hair/balding pattern: Pattern 4 0.7 1.6 6.8 -2.6 -1.3 1.4 -1.4 -1.9 -1.1 0.5 -1.2 -1.2 -1.3 -1.2 1.4 1.3 -1.5 -1.0 -1.5 0.2 -1.5 -0.9 0.1 -0.3 0.5 0.8 -0.8 -0.8 -1.3 -1.1 -1.2 -1.3 2.2
Birth weight of first child 0.4 0.8 2.8 0.3 1.2 -1.7 0.7 -0.2 0.7 -1.2 0.4 1.5 1.1 1.0 -0.9 -0.8 0.6 0.7 0.8 -0.2 0.7 1.1 -0.0 1.0 -1.0 -0.6 1.1 0.8 0.7 0.2 0.6 0.9 -0.6
Peak expiratory flow (PEF) 1.2 2.8 20.9 2.1 0.9 -2.1 1.8 0.9 1.6 -2.1 0.8 -0.3 1.6 1.2 -2.2 -1.6 1.9 1.0 2.0 -0.8 1.8 0.6 -1.3 -0.1 -0.9 -2.1 0.3 -1.2 1.9 0.6 1.6 1.3 -4.6
Pulse wave reflection index 1.5 1.9 3.5 0.5 -1.4 -0.9 -1.3 -1.2 -1.2 -0.6 -1.7 -1.1 -1.6 -1.3 1.0 1.5 -1.4 -1.7 -0.5 -1.8 -1.3 -1.7 -1.7 -1.7 -1.7 -1.9 -1.7 -1.1 -1.5 -1.5 -1.2 -1.6 -0.3
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.9 0.4 -0.2 0.7 0.1 0.3 0.2 0.2 0.4 -0.6 0.2 -0.1 -0.2 -0.2 0.1 0.2 0.4 -0.4 0.2 -0.2 0.0 0.2 0.3 -0.1 0.1 -0.9 0.3 0.3 0.5 0.2 -1.0
Loud music exposure frequency 0.5 0.5 2.2 -0.7 0.5 0.8 0.8 0.3 0.8 -0.3 0.9 -0.1 0.7 0.8 -0.7 -0.9 0.6 0.9 0.2 1.2 0.6 0.7 0.6 0.3 1.5 1.0 0.3 0.4 0.9 0.5 0.6 0.8 -0.2
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 4.7 0.4 0.0 -2.1 -0.1 -0.1 -0.6 -0.8 -1.0 -0.3 0.1 -0.2 -0.2 -0.1 -0.3 -0.3 -0.2 -1.5 -0.3 -0.4 -1.3 0.1 -2.2 -1.9 -0.2 -0.9 -0.1 -0.4 -0.2 -0.1 -1.6
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 1.5 -1.2 0.3 0.7 0.2 -0.2 0.4 -0.0 0.5 0.0 0.5 0.2 -0.1 -0.1 0.1 0.6 -0.4 0.5 -0.0 0.6 0.3 0.5 0.8 0.9 0.4 0.0 0.4 0.3 -0.3 0.5 0.5
Blood clot in the leg (DVT) 0.3 0.3 1.5 -0.1 0.4 0.3 0.3 1.2 0.3 1.2 0.4 0.4 0.3 0.1 -0.1 -0.2 0.5 0.5 -0.1 0.8 0.3 0.7 1.0 0.5 0.7 0.9 0.8 0.3 0.2 0.3 0.5 0.5 0.6
Medication: Paracetamol 2.6 4.4 7.4 -2.0 -2.5 0.9 -2.5 -2.1 -2.3 -0.6 -1.8 -2.3 -2.4 -2.7 2.1 2.7 -2.7 -2.3 -2.5 -1.4 -2.6 -2.3 -1.3 -2.0 -0.8 -0.6 -2.2 -2.0 -2.3 -1.9 -2.2 -2.4 1.6
Headache pain in last month 0.1 0.2 1.6 -0.8 -0.1 0.3 0.4 -0.6 0.6 -0.2 0.5 -0.8 0.4 -0.1 -0.3 -0.3 0.2 0.3 0.0 -0.2 0.4 0.2 -0.5 -0.2 0.3 -0.0 0.0 -1.2 0.5 -0.2 0.4 0.2 -1.3
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.0 0.4 -0.6 -0.5 -0.6 -0.8 -0.7 0.1 -0.5 -0.3 -0.8 -0.4 0.6 0.7 -0.6 -0.9 -0.4 -1.0 -0.6 -0.9 -0.8 -1.4 -1.1 -0.6 -0.5 -0.5 -0.8 -0.8 -0.4 -1.0 -0.1
Glaucoma (self-reported) 2.2 2.5 4.5 -1.4 -2.1 1.4 -1.8 -1.5 -1.6 0.4 -1.6 -1.7 -2.0 -2.1 1.5 1.9 -1.8 -1.7 -2.0 -0.9 -1.8 -1.9 -0.7 -1.5 -0.0 0.1 -1.5 -1.4 -2.0 -1.4 -1.5 -1.8 1.7
Gout (self-reported) 0.6 0.8 4.2 -0.6 0.1 2.0 0.5 0.4 0.5 1.4 0.5 0.4 -0.1 0.4 -0.4 0.2 0.6 0.3 0.1 1.5 0.5 0.5 1.3 0.7 1.9 1.8 0.9 0.7 0.0 0.4 0.6 0.2 1.5
Hypothyroidism/myxoedema (self-reported) 0.5 1.1 4.3 -1.7 -1.0 1.3 -1.0 -1.1 -1.0 1.1 -1.0 -1.0 -1.0 -1.1 1.3 1.0 -1.0 -0.6 -1.4 0.5 -1.0 -0.7 0.2 0.1 1.3 0.4 -0.7 -0.1 -0.8 -0.7 -1.0 -0.7 2.1
Medication: Amlodipine 0.3 0.5 3.2 -0.5 0.2 1.4 -0.3 0.5 -0.3 1.0 0.2 0.7 -0.1 0.2 0.7 0.1 -0.4 0.2 -0.3 0.7 -0.3 0.3 1.3 0.8 0.6 1.2 0.6 0.7 -0.3 0.3 -0.2 0.1 1.8
Medication: Ventolin 100micrograms inhaler 1.0 1.2 3.0 0.3 -1.3 -0.4 -1.0 -1.0 -1.1 -0.9 -1.2 -1.6 -0.9 -1.2 0.7 1.1 -0.9 -1.1 -0.6 -1.5 -1.0 -1.6 -1.4 -1.7 -0.8 -1.4 -1.5 -1.4 -0.8 -0.8 -0.9 -1.0 -0.8
Birth weight 0.5 1.1 2.7 -1.4 1.0 0.3 1.0 0.6 0.8 1.5 0.9 1.3 0.8 1.1 -0.9 -1.0 0.9 1.0 -0.0 1.4 1.1 1.7 0.9 1.3 1.0 1.3 1.6 1.3 0.8 0.4 0.6 1.0 0.9
Chronic bronchitis/emphysema (mother) 1.8 2.1 4.7 -2.0 -1.6 1.0 -1.6 -2.2 -1.2 0.1 -1.1 -1.4 -1.5 -1.7 1.8 1.4 -1.7 -1.4 -1.4 -0.9 -1.7 -1.4 -1.1 -1.3 -0.2 -0.1 -1.2 -1.6 -1.5 -1.8 -1.7 -1.7 1.3
High blood pressure (siblings) 4.0 5.8 9.7 1.0 2.6 0.2 2.8 1.3 3.0 1.0 2.6 1.7 2.8 3.0 -3.0 -2.9 2.5 3.1 2.5 2.7 2.8 2.9 1.8 2.4 2.4 1.6 2.0 1.9 3.1 2.5 2.4 2.9 -1.7
Forced vital capacity (FVC), Best measure 1.0 3.8 11.7 0.7 2.3 -3.1 2.2 0.2 2.0 -3.4 1.4 2.2 2.1 2.4 -2.9 -2.2 2.1 1.6 1.9 0.5 2.1 2.3 -0.2 1.1 -1.0 -1.1 1.6 1.5 2.1 0.7 1.4 2.1 -2.6
Body fat percentage 1.0 4.1 8.6 -2.9 -2.4 1.8 -2.3 -2.2 -2.3 -0.8 -1.8 -2.5 -2.2 -2.4 2.7 2.4 -2.2 -1.9 -2.1 -0.9 -2.2 -1.8 -1.0 -1.7 -0.2 -0.0 -1.8 -2.0 -2.2 -2.0 -2.0 -2.2 2.0
Leg fat percentage (right) 0.3 1.1 2.6 -1.4 -1.3 1.4 -1.1 -1.1 -1.1 -0.4 -0.6 -1.4 -1.1 -1.3 1.6 1.3 -1.1 -0.9 -1.0 -0.2 -1.0 -0.9 -0.3 -0.9 0.2 0.4 -0.9 -1.2 -1.1 -0.9 -0.8 -1.2 0.9
Arm fat-free mass (right) 0.6 3.2 27.8 -3.6 -0.7 2.2 -1.2 -0.1 -1.2 1.5 -0.4 1.2 -1.7 -0.8 1.2 1.4 -1.0 -1.1 -2.8 1.6 -1.1 0.3 1.5 0.9 1.0 2.7 1.0 1.9 -2.1 -0.9 -1.1 -0.8 5.3
Exposure to tobacco smoke outside home 4.0 5.3 11.4 0.2 2.2 1.8 2.3 1.6 2.2 1.8 2.7 2.0 2.2 2.1 -1.4 -2.1 2.4 2.6 2.2 3.4 2.2 2.6 3.1 2.4 3.3 3.3 2.5 2.3 2.1 2.3 2.2 2.3 1.0
Comparative body size at age 10 0.3 0.9 5.1 -1.0 0.6 -1.9 0.8 -0.4 0.6 -1.6 -0.2 -0.5 1.1 0.7 -1.1 -1.1 0.5 0.7 0.4 -0.5 0.7 0.6 -0.9 0.6 -0.3 -1.3 0.3 -1.0 1.2 -0.3 0.5 0.9 -2.3
Number of full brothers 1.9 2.4 5.7 0.4 1.4 -0.1 2.1 -0.2 2.4 1.0 1.6 0.5 1.6 1.8 -2.0 -1.7 2.0 1.7 1.8 1.8 2.0 2.0 0.8 1.3 1.7 0.5 1.0 0.7 2.0 1.4 1.6 1.7 -1.6
Worry too long after embarrassment 0.9 1.6 7.0 2.6 1.5 -0.8 1.2 0.3 0.9 -1.1 1.1 2.1 1.1 1.4 -1.3 -1.2 1.4 0.9 2.4 0.4 1.3 1.0 0.6 0.8 -0.4 -0.1 0.9 1.6 0.9 1.1 1.4 1.0 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.7 0.7 0.6 -0.5 0.4 0.6 0.5 -0.6 0.7 0.6 0.5 0.3 -0.4 -0.6 0.3 0.5 0.2 -0.1 0.1 0.5 -0.1 0.3 -0.6 0.1 0.1 0.7 0.4 0.8 0.2 0.5 -0.7
Wheeze or whistling in the chest in last year 0.3 0.6 2.3 -0.4 -0.7 -0.3 -0.5 -1.2 -0.5 -0.4 -0.2 -1.1 -0.4 -0.8 0.6 0.3 -0.6 -0.4 -0.1 -1.2 -0.6 -0.7 -1.5 -1.1 -0.7 -0.8 -1.3 -0.9 -0.3 -0.2 -0.7 -0.6 -1.0
Number of children fathered 1.2 1.4 6.6 -1.8 -1.3 1.1 -1.4 -0.8 -1.2 0.6 -0.8 -0.5 -1.6 -0.9 1.5 1.5 -1.3 -1.1 -1.2 0.2 -1.2 -0.6 -0.2 -0.6 0.4 0.9 -1.1 0.8 -1.6 -0.6 -1.4 -1.1 2.6
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 7.2 2.7 1.2 -2.1 0.6 -0.3 0.9 -1.2 0.7 1.7 0.8 0.9 -1.2 -0.7 0.5 0.4 1.8 -0.9 0.5 0.4 -0.5 -0.3 -1.7 -1.0 0.3 1.3 0.6 0.6 0.4 0.5 -1.4
Age at first live birth 0.2 0.4 2.9 0.4 0.1 -1.5 -0.2 0.2 -0.5 -1.4 -0.6 0.8 -0.0 0.0 0.1 0.2 -0.3 -0.2 -0.2 -1.1 -0.2 0.0 -0.7 0.1 -1.7 -1.2 0.3 -0.2 -0.3 -0.5 -0.2 0.1 -0.7
Pulse wave peak to peak time 0.2 0.2 0.5 -0.2 0.6 0.0 0.4 0.3 0.5 -0.1 0.6 0.5 0.6 0.7 -0.2 -0.6 0.4 0.6 0.6 0.5 0.3 0.4 0.6 0.7 0.5 0.6 0.6 0.2 0.6 0.5 0.4 0.5 -0.0
Health satisfaction 0.6 0.8 4.2 -1.4 0.1 2.0 0.0 1.1 0.0 0.6 1.0 -0.1 0.4 -0.3 0.5 -0.1 -0.2 0.6 -0.8 0.7 -0.2 0.5 1.1 1.2 1.4 1.7 0.9 0.2 0.1 0.7 0.1 0.5 1.4
Shortness of breath walking on level ground 0.2 0.3 1.0 -0.4 -0.6 1.0 -0.5 -0.4 -0.4 1.0 -0.2 -0.8 -0.4 -0.7 0.2 0.6 -0.3 -0.3 -0.5 -0.2 -0.5 -0.6 -0.2 -0.4 0.3 0.2 -0.5 -0.7 -0.4 -0.4 -0.3 -0.5 0.3
Qualifications: College or University degree 0.7 2.3 12.1 0.5 -0.4 -2.4 -0.9 -0.8 -1.2 -2.2 -1.6 -0.2 -0.4 -0.7 0.6 0.4 -0.9 -1.0 -0.2 -2.9 -0.9 -1.1 -2.3 -1.4 -3.5 -3.1 -0.7 -1.5 -0.6 -1.3 -1.0 -0.8 -1.8
Eye problems/disorders: None of the above 0.6 0.7 2.5 -0.2 -0.5 -1.1 -0.3 -1.2 -0.4 -1.6 -1.0 -0.6 -0.5 -0.2 0.7 0.5 -0.2 -0.8 -0.4 -1.0 -0.2 -0.5 -1.4 -0.9 -1.4 -1.5 -0.5 -0.5 -0.4 -0.9 -0.5 -0.6 -0.8
Mouth/teeth dental problems: Loose teeth 1.7 2.0 4.0 -1.4 -1.5 1.7 -1.8 -0.4 -1.8 -0.1 -0.9 -1.6 -1.5 -1.7 2.0 1.6 -1.8 -1.2 -1.9 -0.7 -1.8 -1.6 -0.7 -1.4 0.3 0.3 -1.5 -0.4 -1.5 -0.9 -1.9 -1.4 2.0
Emphysema/chronic bronchitis 1.0 1.1 3.1 -1.7 -1.0 1.7 -1.1 -0.2 -1.3 1.3 -0.7 -1.2 -0.7 -1.2 1.5 0.8 -1.3 -0.4 -1.8 0.2 -1.3 -0.8 -0.0 -0.4 0.9 0.7 -0.9 -0.3 -0.7 -0.4 -1.5 -0.7 1.8
Medication for pain relief, constipation, heartburn 0.5 0.8 1.9 0.9 1.2 -0.6 1.1 0.1 0.9 -0.7 0.6 0.9 1.1 1.2 -1.2 -1.4 1.3 0.9 1.0 -0.1 1.1 0.8 0.1 0.4 -0.4 -0.3 1.1 0.6 1.0 0.7 1.0 0.8 -1.1
Neck or shoulder pain in last month 0.5 0.7 3.2 -1.4 0.1 1.3 -0.0 -0.2 0.1 1.2 1.0 0.4 0.2 -0.0 0.0 -0.0 0.0 0.4 -0.7 1.3 0.0 0.5 1.6 1.4 1.5 1.8 0.5 0.2 0.1 0.6 0.2 0.3 1.6
Medication: Blood pressure 0.4 0.7 2.9 -1.1 0.7 0.5 0.8 0.2 1.0 0.3 0.5 -0.1 1.0 0.8 -0.8 -0.9 0.5 1.2 0.3 1.4 0.7 1.1 0.8 1.7 1.5 0.7 0.5 0.4 1.2 0.8 0.4 1.0 -0.0
Angina (self-reported) 0.8 1.0 2.2 -0.8 -1.2 -0.1 -1.1 -1.1 -1.0 -0.1 -1.1 -0.7 -1.3 -0.9 1.1 1.1 -0.9 -1.4 -0.2 -1.2 -1.0 -1.0 -0.8 -0.8 -1.4 -0.7 -0.8 -1.1 -1.5 -1.3 -0.7 -1.3 0.5
Migraine (self-reported) 1.4 1.8 7.7 0.9 1.4 -0.1 1.5 0.1 1.6 -0.2 1.6 0.6 1.8 1.6 -1.5 -1.6 1.3 1.6 1.4 0.1 1.4 1.2 0.6 0.8 -0.2 -0.1 1.6 -1.0 1.9 1.1 1.8 1.5 -2.8
Medication: Ibuprofen 0.3 0.4 1.0 0.2 -0.5 -1.0 -0.6 -0.6 -0.5 1.0 -0.3 -0.2 -0.7 -0.6 0.5 0.7 -0.7 -0.8 -0.3 -0.5 -0.6 -0.5 -0.5 -0.6 -0.6 -0.5 -1.0 0.5 -0.7 -0.3 -0.6 -0.6 0.5
Medication: Allopurinol 0.8 1.1 3.1 -0.2 0.7 1.4 1.2 0.2 1.1 0.7 1.1 0.3 0.8 1.1 -1.2 -0.8 1.2 1.1 1.1 1.5 1.2 1.1 1.1 1.0 1.8 1.3 1.1 0.2 1.1 0.9 1.3 0.8 -0.3
Medication: Omeprazole 2.1 2.5 5.3 -1.4 -2.0 2.1 -1.8 -0.4 -1.9 0.4 -1.2 -2.2 -1.7 -2.1 1.8 2.0 -2.0 -1.4 -2.3 -0.4 -1.9 -1.8 -0.5 -1.7 0.5 0.5 -1.7 -1.3 -1.6 -1.0 -1.5 -1.6 1.5
Medication: Seretide 50 evohaler 1.4 1.7 4.1 0.4 -1.7 1.4 -1.6 -0.2 -1.4 0.9 -1.1 -2.0 -1.5 -1.8 1.6 1.6 -1.6 -1.2 -0.9 -1.0 -1.6 -1.9 -0.3 -1.2 -0.2 0.1 -1.2 -1.6 -1.5 -0.5 -0.9 -1.5 0.8
Mean time to correctly identify matches 0.1 0.3 1.5 -0.3 0.2 0.7 0.2 0.6 0.2 1.2 0.3 0.6 0.1 0.2 -0.2 -0.0 0.2 0.2 -0.6 0.7 0.3 0.5 0.6 0.1 0.6 0.7 0.3 1.1 0.0 0.3 0.1 0.3 1.0
Heart disease (mother) 1.8 2.1 4.1 0.4 1.7 -1.5 1.8 0.7 1.8 -1.0 1.3 1.5 1.6 1.9 -1.6 -1.8 1.9 1.4 1.8 1.1 1.9 1.9 0.7 2.0 0.2 0.0 1.5 1.2 1.6 1.0 1.6 1.7 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 1.3 0.1 0.1 0.4 -0.2 1.1 -0.0 1.1 0.2 0.3 0.1 -0.2 0.0 -0.2 -0.3 0.1 -0.3 0.1 -0.4 -0.1 -0.0 0.1 0.1 -0.0 -0.4 1.0 -0.0 0.2 -0.4 0.0 0.7
Whole body fat mass 0.8 3.4 13.1 -3.6 -1.9 2.2 -2.0 -1.6 -2.0 0.1 -1.3 -1.4 -2.1 -2.0 2.4 2.2 -1.9 -1.6 -2.6 0.1 -1.9 -1.0 -0.1 -0.8 0.4 1.0 -0.8 -0.7 -2.2 -1.8 -1.8 -1.8 3.4
Leg fat mass (right) 0.8 3.0 10.6 -3.3 -1.9 2.1 -1.9 -1.5 -1.9 0.0 -1.2 -1.4 -1.9 -1.9 2.2 2.0 -1.8 -1.5 -2.4 0.1 -1.8 -1.1 -0.0 -0.7 0.5 1.1 -0.8 -0.9 -2.0 -1.6 -1.6 -1.7 3.0
Arm predicted mass (right) 0.6 3.2 28.0 -3.6 -0.8 2.2 -1.2 -0.2 -1.1 1.2 -0.4 1.1 -1.7 -0.8 1.2 1.5 -1.0 -1.1 -2.8 1.5 -1.1 0.3 1.4 0.8 0.9 2.7 1.0 1.9 -2.2 -1.0 -1.1 -0.9 5.3
Pulse rate, automated reading 1.6 5.3 13.7 -1.7 -2.8 0.3 -2.5 -2.8 -2.3 -1.5 -2.3 -3.7 -2.3 -2.6 2.1 2.4 -2.4 -2.3 -2.3 -1.8 -2.3 -2.9 -1.9 -2.7 -0.5 -1.7 -2.9 -3.1 -1.9 -2.3 -2.1 -2.5 0.2
Alcohol intake frequency. 0.9 2.0 6.6 -0.5 1.0 1.4 1.7 0.5 2.0 -0.5 1.6 -0.1 1.4 1.2 -1.2 -1.5 1.8 1.7 1.2 2.3 1.6 1.5 1.3 0.8 2.6 1.7 0.9 0.9 1.7 1.4 1.5 1.5 -0.4
Comparative height size at age 10 0.7 3.7 35.2 -2.0 0.8 -0.4 -0.5 1.0 -0.5 1.6 -0.1 3.8 -0.9 0.5 -0.1 0.6 -0.5 -0.5 -1.6 1.7 -0.4 1.4 2.0 1.9 0.1 2.2 2.0 4.7 -1.7 -0.5 -0.9 0.1 5.9
Number of full sisters 2.4 2.9 6.9 1.9 1.9 0.1 1.8 0.4 2.1 0.7 2.1 1.8 1.7 2.1 -2.0 -1.8 1.6 1.9 2.1 1.9 1.7 1.7 1.4 1.0 1.9 1.5 1.0 2.6 1.9 2.2 1.4 1.6 -0.4
Suffer from ‘nerves’ 0.2 0.3 1.6 -1.0 -0.1 1.2 -0.2 -0.8 -0.0 -1.2 0.2 0.2 -0.2 -0.0 0.3 0.2 0.2 0.0 -0.2 0.5 -0.0 0.3 0.5 0.5 0.4 0.9 0.4 -0.0 -0.3 -0.0 0.0 -0.1 1.0
Overall health rating 0.8 1.6 8.6 -1.9 -0.2 2.7 -0.4 0.5 -0.1 2.1 1.0 0.1 -0.4 -0.4 1.0 0.4 -0.5 0.2 -1.0 1.7 -0.5 0.4 1.7 1.1 1.9 2.8 0.6 0.7 -0.5 0.5 -0.3 0.0 2.9
Chest pain or discomfort 0.1 0.2 0.7 -0.1 -0.5 0.7 0.3 0.7 0.3 0.7 0.1 -0.8 -0.1 -0.1 0.1 0.1 0.5 -0.1 0.3 0.3 0.4 -0.0 -0.1 -0.5 0.6 0.4 -0.3 -0.4 0.1 0.2 0.4 0.0 -0.7
Had major operations 0.6 0.7 1.4 -1.1 -1.0 1.2 -0.7 0.5 -0.8 1.1 -0.6 -1.1 -0.9 -1.1 1.1 1.0 -0.4 -0.7 -1.0 0.2 -0.6 -0.7 0.2 -0.2 0.4 0.6 -0.3 -1.0 -0.9 -0.6 -0.4 -0.8 1.2
Age at last live birth 0.5 0.8 3.4 0.5 -0.3 -1.7 -0.6 -0.8 -0.8 -1.6 -1.0 0.5 -0.6 -0.4 0.2 0.7 -0.6 -0.8 -0.3 -1.2 -0.6 -0.4 -1.1 -0.6 -1.8 -1.5 -0.6 0.2 -0.7 -0.8 -0.8 -0.5 -0.2
Family relationship satisfaction 0.6 0.7 3.2 -1.8 -1.0 0.6 -0.9 -0.9 -0.9 -0.3 -0.7 -1.0 -0.9 -0.9 1.1 0.9 -0.6 -0.7 -1.0 -0.2 -0.8 -0.5 -0.4 -0.3 0.0 0.2 -0.6 -1.2 -0.9 -0.9 -0.8 -0.8 0.7
Leg pain on walking 2.7 3.4 6.4 -2.2 -2.2 2.3 -2.2 -1.1 -2.1 0.8 -1.0 -2.0 -2.1 -2.3 2.5 2.1 -1.9 -1.8 -2.5 -0.7 -2.1 -1.9 -0.5 -1.4 0.5 0.9 -1.6 -1.3 -2.1 -1.5 -1.9 -2.0 2.5
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 3.2 0.7 0.9 0.1 0.7 1.8 0.6 -0.2 1.3 1.1 0.7 0.9 -0.7 -0.7 0.6 0.7 0.9 0.9 0.6 0.6 1.5 1.4 0.6 1.0 1.1 0.9 0.6 1.1 1.1 0.8 0.3
Commuting to job workplace: Car/motor vehicle 5.2 5.9 9.8 -1.7 -3.1 1.3 -2.8 -2.5 -2.8 0.1 -2.1 -2.4 -3.1 -2.7 3.0 3.0 -2.5 -2.9 -2.4 -2.0 -2.6 -2.9 -1.7 -2.7 -0.9 -0.8 -2.5 -2.6 -2.9 -2.5 -2.2 -3.1 1.5
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.9 -1.2 -0.6 -0.7 -1.0 -0.5 -1.1 -0.3 -1.3 -0.2 -0.8 -0.9 0.9 0.8 -1.1 -1.0 -1.2 -1.0 -1.1 -0.7 -0.7 -0.2 -1.2 -0.8 -0.2 -0.6 -1.0 -1.4 -1.1 -0.8 0.9
Medication: Aspirin 0.2 0.2 0.9 0.3 0.5 -0.7 0.4 1.0 0.5 0.1 0.2 0.9 0.4 0.5 -0.2 -0.5 0.3 0.3 0.6 0.6 0.3 0.6 0.3 0.6 0.2 0.1 0.1 0.7 0.4 0.2 0.1 0.6 -0.1
Supplements: Vitamin C 0.5 0.6 2.7 1.6 0.6 -1.4 0.8 0.7 0.9 0.3 0.1 1.1 0.4 0.7 -0.8 -0.5 1.1 0.1 1.2 -0.5 0.8 0.5 -0.4 0.1 -1.0 -0.8 0.7 0.4 0.3 0.2 0.7 0.5 -1.2
Knee pain experienced in last month 3.1 4.9 19.9 -2.9 -2.2 1.5 -2.8 -1.6 -2.6 0.4 -2.0 -1.1 -2.7 -2.4 2.6 2.6 -2.8 -2.3 -3.4 -0.2 -2.8 -2.0 0.5 0.1 0.1 0.9 -1.3 -0.6 -2.9 -1.6 -2.3 -2.4 4.5
Hypertension (Self-reported) 1.2 3.3 7.7 -0.7 1.9 1.1 1.6 1.3 1.7 1.4 1.6 1.8 1.7 2.0 -1.4 -1.7 1.3 2.1 0.9 2.8 1.5 2.3 2.3 2.5 2.3 2.4 2.2 2.3 1.6 1.6 1.2 2.0 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 1.2 -0.0 0.1 -0.5 0.1 0.7 0.1 -1.1 -0.1 0.2 0.1 0.1 -0.3 -0.2 0.1 0.0 0.2 -0.3 0.1 0.2 0.0 0.7 -0.1 -0.3 0.4 -0.4 0.0 -0.1 -0.0 0.3 -0.3
Illnesses of father: Heart disease 0.2 0.2 1.7 -0.3 0.3 0.5 0.4 0.7 0.4 -0.7 -0.0 0.5 0.3 0.5 -0.1 -0.3 0.5 0.3 -0.1 0.2 0.4 0.6 0.5 0.6 -0.3 0.4 1.3 -0.0 0.1 0.1 0.6 0.5 0.0
Illnesses of siblings: Diabetes 2.3 2.8 12.7 1.3 1.4 -0.7 2.0 -0.3 2.4 -1.5 1.6 -0.1 2.1 1.5 -2.6 -2.2 2.1 2.0 2.2 0.3 2.0 1.3 -0.3 0.5 0.8 -0.6 0.6 -0.5 2.4 1.4 1.8 1.7 -3.6
Smoking status: Previous 0.7 1.0 3.9 1.3 1.2 -2.0 1.0 1.0 1.1 -0.8 0.7 1.5 0.9 1.1 -1.1 -1.0 1.1 0.6 0.9 0.1 1.1 1.1 -0.0 0.7 -0.4 -0.7 0.5 1.1 0.9 0.5 0.8 0.9 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 3.3 -0.7 0.3 -0.6 -0.4 0.4 -0.6 -0.3 -0.0 1.5 -0.2 0.0 0.1 0.3 -0.2 -0.3 -0.8 0.1 -0.4 0.3 0.5 0.9 -0.4 0.3 0.6 1.4 -0.6 -0.1 -0.4 0.1 1.8
Whole body fat-free mass 0.6 3.4 29.3 -4.0 -0.6 1.8 -1.1 -0.1 -1.2 1.6 -0.5 1.5 -1.6 -0.7 1.1 1.3 -1.0 -1.0 -3.1 1.5 -1.0 0.6 1.4 1.1 0.7 2.5 1.2 2.1 -2.1 -1.1 -1.3 -0.7 5.4
Leg fat-free mass (right) 0.7 3.8 25.4 -4.2 -1.4 1.4 -1.8 -0.8 -2.0 0.9 -1.5 0.5 -2.2 -1.6 1.6 2.0 -1.8 -1.7 -3.4 0.5 -1.9 -0.3 0.5 0.3 -0.2 1.5 0.3 1.0 -2.7 -1.9 -1.9 -1.4 5.0
Arm fat percentage (left) 0.9 3.8 7.5 -2.7 -2.2 1.3 -2.2 -2.2 -2.3 -0.4 -1.8 -2.4 -2.1 -2.4 2.5 2.2 -2.1 -1.9 -2.1 -1.1 -2.2 -1.8 -1.2 -1.6 -0.5 -0.4 -1.7 -2.1 -2.0 -2.1 -2.0 -2.2 1.6
Average weekly red wine intake 0.1 0.1 0.5 -0.0 0.4 -0.4 -0.0 0.4 0.3 0.4 0.3 0.2 0.4 0.2 -0.0 -0.4 -0.2 0.4 0.2 -0.1 -0.1 0.2 0.1 0.7 0.0 -0.0 -0.0 -0.0 0.4 0.4 -0.1 0.4 -0.2
Handedness (chirality/laterality): Left-handed 0.8 1.0 5.0 -2.0 -0.6 1.4 -1.0 0.1 -1.3 1.4 -0.4 -0.5 -0.5 -1.0 1.1 0.5 -1.1 -0.3 -1.7 0.6 -1.1 -0.4 0.9 0.7 1.1 1.3 -0.0 -0.4 -0.6 -0.2 -0.8 -0.4 2.2
Mood swings 0.3 0.6 3.0 -0.2 0.1 1.7 0.2 0.7 0.3 1.5 0.8 0.3 -0.0 0.3 0.5 -0.2 0.2 0.3 0.3 1.1 0.3 0.5 1.3 0.9 1.0 1.7 0.9 0.5 -0.1 0.7 0.5 0.2 1.2
Loneliness, isolation 0.1 0.1 1.8 -0.5 -0.2 0.4 -0.0 0.0 -0.0 -1.4 -0.4 -0.3 -0.2 -0.1 0.6 0.3 0.0 -0.1 0.1 0.1 0.0 -0.0 0.1 0.4 -0.1 0.1 0.1 -0.4 -0.2 0.0 0.1 -0.1 0.0
Long-standing illness, disability or infirmity 0.7 1.0 4.2 -1.5 -1.2 2.0 -1.0 0.5 -0.7 1.2 -0.3 -0.9 -1.2 -1.4 1.2 1.0 -0.7 -0.8 -1.5 0.3 -0.9 -0.7 0.5 0.1 0.7 1.1 -0.3 -0.5 -1.2 -0.3 -0.5 -0.8 2.0
Ever had bowel cancer screening 1.5 1.8 3.9 0.5 1.5 -0.2 1.6 1.1 1.5 -0.3 1.2 1.8 1.3 1.6 -1.7 -1.5 1.6 1.3 1.7 1.0 1.7 1.9 0.8 1.6 0.2 0.5 2.0 1.3 1.1 0.6 1.5 1.5 -0.5
Diabetes diagnosed by doctor 0.5 0.8 4.1 0.7 -0.6 -0.3 0.1 -0.1 0.3 -1.5 -0.3 -1.8 -0.1 -0.5 0.1 -0.2 0.1 -0.3 0.4 -0.8 0.1 -0.8 -1.6 -1.6 0.0 -1.7 -1.7 -0.8 0.4 -0.6 -0.3 -0.3 -2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.6 -0.5 0.4 1.1 0.5 1.3 0.3 0.4 0.9 0.4 0.3 0.2 -0.1 -0.1 0.8 0.6 -0.1 1.0 0.6 0.8 0.8 0.3 0.7 1.2 0.5 0.8 0.3 0.6 0.5 0.5 0.5
Friendships satisfaction 1.8 2.3 4.1 -1.9 -2.0 0.2 -1.5 -0.9 -1.6 -0.8 -1.7 -1.7 -2.0 -1.8 2.0 2.0 -1.1 -1.8 -1.9 -1.0 -1.4 -1.4 -1.3 -0.9 -0.7 -0.7 -1.4 -1.8 -1.9 -1.5 -1.4 -1.7 0.8
Qualifications: nursing, teaching 0.2 0.4 3.0 1.4 -0.1 -0.6 -0.2 -0.3 -0.2 0.5 -0.3 0.3 -0.1 -0.1 0.3 0.2 -0.1 -0.4 0.3 -1.4 -0.1 -0.6 -0.6 -0.5 -1.7 -0.9 0.1 -0.6 -0.4 0.0 0.2 -0.5 -0.8
Commuting to job workplace: Walk 0.3 0.3 1.4 0.9 0.8 -1.2 0.3 0.8 -0.0 0.5 -0.3 0.8 0.7 0.3 -0.5 -0.6 0.2 0.4 0.5 -0.1 0.2 0.4 0.1 0.4 -1.0 -0.7 0.5 0.8 0.5 0.4 0.3 0.6 -0.4
Eye problems/disorders: Cataract 0.6 0.7 1.5 -0.7 -0.8 0.2 -1.1 -0.4 -1.1 0.8 -0.5 -0.2 -1.1 -1.1 0.7 1.0 -1.2 -0.8 -1.0 -0.5 -1.2 -0.8 -0.4 -0.9 -0.7 0.2 -1.2 -0.1 -1.1 -0.4 -1.2 -1.1 1.0
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 2.0 -0.5 0.4 -1.0 0.5 0.2 0.5 -1.4 0.2 -0.0 0.6 0.4 -1.0 -0.5 0.5 0.5 0.2 0.3 0.6 0.6 -0.4 0.3 0.1 -0.6 -0.1 0.2 0.7 0.3 0.2 0.7 -0.8
Medication for cholesterol 0.7 1.0 2.8 0.5 -1.1 -0.2 -1.1 -0.2 -1.1 -0.1 -0.7 -0.7 -1.0 -1.1 0.9 1.1 -0.9 -1.3 -0.9 -1.7 -1.0 -1.5 -0.9 -1.3 -1.2 -1.0 -1.3 -0.8 -1.1 -0.7 -0.8 -1.2 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 1.9 -1.4 -0.2 0.6 0.0 -0.9 0.3 0.2 0.1 -0.4 -0.1 -0.0 -0.1 0.1 0.1 0.1 -0.3 0.7 0.2 0.3 0.1 0.1 1.2 0.3 -0.2 0.5 0.0 -0.3 -0.3 -0.0 1.1
Back pain experienced in last month 3.9 5.6 11.5 -1.8 -2.6 0.8 -3.1 -2.3 -2.6 0.6 -2.1 -1.5 -3.2 -2.5 3.2 3.1 -3.2 -2.8 -2.9 -1.3 -3.2 -2.4 -0.5 -1.4 -0.8 0.0 -2.0 -1.1 -3.3 -2.1 -2.6 -2.9 3.4
Mineral and other dietary supplements 0.5 0.7 1.5 0.4 1.1 -0.5 1.0 -0.0 0.8 0.2 0.8 1.1 1.1 1.1 -1.2 -1.0 0.7 1.1 0.9 0.6 0.9 1.2 0.4 1.0 0.4 -0.0 1.1 0.9 1.1 0.5 0.7 1.2 -0.4
Breast cancer (self-reported) 1.1 1.3 2.8 -1.7 -1.3 1.6 -1.4 -0.7 -1.3 -0.5 -0.5 -1.1 -1.2 -1.4 1.7 1.3 -1.4 -1.0 -1.3 -0.7 -1.4 -1.0 -0.2 -0.6 -0.3 0.5 -0.6 -1.0 -1.4 -0.6 -1.2 -1.2 1.5
Asthma (self-reported) 0.6 1.3 5.4 -0.1 -0.9 -1.8 -0.8 -1.2 -0.8 -2.3 -0.8 -1.3 -0.6 -1.1 0.5 0.7 -0.8 -0.9 -0.2 -1.6 -0.8 -1.0 -1.7 -1.1 -1.4 -1.7 -1.8 -0.7 -0.5 -0.4 -0.9 -0.8 -1.1
Osteoporosis (self-reported) 0.3 0.4 4.5 -0.1 -0.3 2.1 -0.1 0.6 0.2 0.8 0.4 -0.0 -0.3 0.1 0.4 0.3 -0.2 0.1 0.3 0.2 -0.1 -0.1 1.0 0.7 0.4 1.4 0.6 -0.1 -0.4 1.0 0.5 -0.2 0.9
Osteoarthritis (self-reported) 4.3 5.5 22.1 -2.1 -2.5 1.1 -3.0 -1.4 -2.6 0.5 -2.1 -0.6 -3.6 -2.4 2.8 3.0 -2.7 -3.0 -2.7 -0.3 -2.8 -2.0 -0.0 -0.9 -0.4 0.5 -1.8 0.2 -3.7 -2.1 -2.5 -3.0 4.7
Medication: Aspirin 0.1 0.2 0.7 0.1 0.4 -0.8 0.4 0.9 0.5 0.3 0.1 0.6 0.3 0.4 -0.2 -0.5 0.4 0.2 0.5 0.6 0.3 0.5 0.2 0.5 0.3 -0.1 -0.2 0.6 0.4 0.0 0.1 0.5 -0.2
Medication: Gliclazide 0.7 0.8 4.9 0.8 0.5 -1.8 0.7 0.1 0.8 -1.9 0.3 0.0 0.6 0.4 -0.9 -0.8 0.7 0.3 1.0 -0.7 0.7 0.4 -1.3 -0.4 -0.8 -1.7 -0.7 0.1 0.9 -0.2 0.2 0.4 -2.2
Illnesses of father: None of the above (group 1) 2.1 2.6 5.1 -0.7 -2.0 0.6 -2.0 -1.4 -2.0 0.4 -1.4 -1.4 -2.1 -2.1 1.7 1.9 -1.9 -2.0 -1.4 -1.3 -1.9 -2.1 -0.6 -1.1 -0.2 -0.5 -1.6 -0.8 -2.2 -1.2 -1.7 -2.0 2.1
Smoking status: Current 0.8 1.3 3.3 -1.3 -1.4 1.7 -1.0 -0.6 -0.9 1.5 -0.3 -1.8 -1.0 -1.2 1.7 1.0 -0.9 -0.8 -1.0 -0.3 -1.1 -1.1 -0.9 -1.5 0.8 0.2 -1.8 -0.9 -0.7 -0.6 -1.3 -1.1 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 7.8 1.3 0.2 -1.0 0.5 0.3 0.5 -2.5 0.3 -0.9 0.7 0.3 -0.7 -0.6 0.4 0.4 1.0 -0.6 0.5 -0.3 -1.1 -0.8 -0.4 -1.4 -0.6 -0.9 1.1 0.1 0.5 0.4 -2.8
Whole body water mass 0.6 3.3 28.9 -4.0 -0.6 1.8 -1.1 0.0 -1.2 1.6 -0.5 1.5 -1.6 -0.7 1.1 1.3 -0.9 -1.0 -3.0 1.5 -1.0 0.6 1.4 1.1 0.7 2.6 1.2 2.1 -2.0 -1.1 -1.2 -0.7 5.4
Leg predicted mass (right) 0.7 3.7 25.2 -4.2 -1.3 1.4 -1.8 -0.8 -1.9 0.9 -1.5 0.6 -2.1 -1.5 1.6 2.0 -1.7 -1.7 -3.3 0.5 -1.8 -0.2 0.5 0.4 -0.1 1.6 0.4 1.1 -2.6 -1.8 -1.9 -1.4 5.0
Arm fat mass (left) 0.8 3.3 10.3 -3.2 -2.0 1.9 -2.1 -1.6 -2.1 0.4 -1.5 -1.4 -2.1 -2.1 2.3 2.1 -2.0 -1.7 -2.5 -0.2 -2.0 -1.3 -0.2 -0.9 0.2 0.8 -1.0 -0.9 -2.2 -1.8 -1.9 -1.9 3.1
Number of self-reported non-cancer illnesses 0.2 0.3 0.9 -0.7 -0.7 0.6 -0.6 -0.3 -0.4 0.2 -0.3 -0.7 -0.8 -0.8 0.7 0.8 -0.6 -0.5 -0.4 0.4 -0.6 -0.5 0.3 0.2 0.7 0.3 -0.8 -0.3 -0.6 -0.2 -0.3 -0.6 0.9
Average weekly champagne plus white wine intake 0.1 0.1 0.3 -0.4 0.0 -0.4 -0.3 0.0 -0.3 0.3 -0.3 0.5 -0.1 -0.2 0.3 0.2 -0.4 -0.2 -0.4 -0.3 -0.4 0.0 0.1 0.4 -0.5 -0.0 0.4 -0.5 -0.3 -0.5 -0.1 -0.1 0.3
Miserableness 0.5 0.8 2.9 1.7 0.9 -0.3 0.9 1.4 1.0 0.5 0.9 1.0 0.8 1.1 -0.5 -0.8 0.9 0.7 1.6 0.1 0.9 0.7 0.4 0.8 -0.1 0.1 0.8 0.7 0.7 0.9 1.0 0.9 -1.0
Guilty feelings 0.2 0.3 1.9 0.1 -0.6 1.0 -0.7 0.4 -0.7 -0.1 -0.1 -0.2 -0.7 -0.6 1.4 0.7 -0.6 -0.6 -0.4 -0.7 -0.6 -0.6 -0.2 -0.5 -0.7 0.2 -0.1 -0.3 -0.9 -0.4 -0.2 -0.7 0.5
Wears glasses or contact lenses 1.0 1.1 2.2 -0.3 -1.3 1.1 -1.3 0.1 -1.3 0.5 -1.1 -1.0 -1.2 -1.2 1.5 1.2 -1.2 -1.1 -1.1 -1.1 -1.2 -1.4 -0.9 -1.4 -0.7 -0.2 -0.9 -0.5 -1.3 -0.6 -1.2 -1.2 0.9
Ever taken oral contraceptive pill 0.8 0.9 2.2 -0.2 -0.6 -1.1 -0.9 -1.4 -0.8 -1.3 -1.0 -0.7 -0.7 -0.9 0.6 0.7 -1.1 -0.9 -0.8 -1.5 -0.9 -0.9 -1.3 -0.9 -1.4 -1.4 -0.9 -0.8 -0.7 -1.2 -1.0 -0.9 -0.3
Hearing aid user 0.6 0.7 2.0 0.1 -0.9 -0.8 -0.9 -0.3 -1.0 -0.6 -0.8 -0.3 -1.4 -0.9 0.8 1.2 -0.6 -1.4 -0.4 -0.7 -0.8 -0.9 -0.4 -0.6 -0.8 -0.4 -0.9 0.0 -1.4 -0.6 -0.8 -1.2 0.9
Mother’s age at death 0.3 0.4 1.1 0.3 -0.7 0.0 -0.6 0.3 -0.8 0.3 -1.1 -0.2 -0.8 -0.6 0.7 0.9 -0.4 -0.8 -0.8 -0.5 -0.4 -0.7 -0.4 -0.5 -0.3 -0.5 -0.4 -0.1 -0.8 -0.8 -0.5 -0.6 0.5
Financial situation satisfaction 0.1 0.1 0.6 0.0 -0.0 0.0 -0.1 0.5 -0.4 0.8 -0.0 -0.4 0.1 -0.2 0.3 -0.3 -0.2 0.2 -0.2 0.2 -0.2 -0.1 -0.4 -0.0 0.2 -0.0 -0.6 0.0 0.3 0.3 -0.3 0.1 -0.4
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.5 0.5 1.0 -1.3 1.1 -0.1 1.1 -0.6 0.6 1.4 0.5 1.3 -1.6 -0.8 1.2 0.5 1.1 0.6 1.3 1.3 0.6 1.6 -0.2 0.1 1.4 0.8 0.5 0.4 1.3 0.7 -0.3
Commuting to job workplace: Public transport 1.3 1.5 2.5 0.9 1.5 -0.1 1.4 1.3 1.3 -0.2 1.4 1.2 1.6 1.3 -1.5 -1.4 1.3 1.6 1.1 1.0 1.2 1.5 1.0 1.2 0.4 0.8 1.4 1.2 1.4 1.4 1.2 1.6 -0.6
Eye problems/disorders: Glaucoma 2.0 2.4 4.3 -1.8 -1.9 1.3 -1.8 -1.8 -1.6 -0.2 -1.3 -1.7 -1.7 -2.1 1.3 1.7 -1.8 -1.5 -2.1 -0.8 -1.8 -1.7 -0.6 -1.3 -0.1 0.0 -1.5 -1.8 -1.8 -1.5 -1.5 -1.7 1.5
Medication: Blood pressure 0.7 1.3 8.0 -2.1 0.3 1.9 -0.0 -0.3 0.1 0.9 0.2 0.8 -0.1 0.4 0.2 -0.0 -0.2 0.5 -0.5 2.1 -0.0 1.0 1.6 1.2 1.6 2.3 1.2 1.1 -0.1 -0.1 -0.1 0.3 2.8
Pain type(s) experienced in last month: Hip pain 1.9 2.4 6.1 -2.5 -1.9 1.1 -1.8 -1.7 -1.5 0.2 -1.3 -1.8 -1.9 -1.8 1.7 1.7 -1.8 -1.6 -2.2 -0.7 -1.7 -1.3 -0.7 -0.6 -0.3 -0.1 -1.3 -1.7 -1.8 -1.6 -1.6 -1.7 1.5
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.5 -0.3 -0.8 1.2 -0.7 0.3 -0.5 0.7 -0.2 -0.8 -0.8 -0.6 1.0 0.7 -0.3 -0.6 -0.8 0.0 -0.6 -0.8 0.2 -0.7 0.6 0.9 -0.7 -0.4 -0.8 -0.0 -0.4 -0.8 0.9
High cholesterol (Self-reported) 0.2 0.3 1.5 -0.5 0.4 -0.4 0.5 -0.1 0.5 -0.4 -0.0 0.5 0.3 0.5 -0.1 -0.4 0.5 0.4 0.5 0.8 0.6 0.8 0.7 1.2 0.5 0.2 0.8 0.2 0.3 0.0 0.6 0.6 0.3
Medication: Bendroflumethiazide 0.4 0.7 2.7 -1.3 0.9 0.3 0.3 -0.3 0.4 0.1 0.4 0.9 0.5 0.8 -0.5 -0.5 0.0 0.8 0.4 1.6 0.2 1.2 1.0 1.2 1.1 1.4 0.7 1.2 0.5 0.3 -0.1 0.6 1.4
Medication: Paracetamol 2.0 3.1 6.1 -2.0 -2.2 1.6 -2.1 -1.3 -2.0 0.2 -1.2 -2.0 -2.0 -2.5 2.0 2.2 -2.3 -1.8 -2.2 -0.6 -2.2 -1.9 -0.5 -1.5 0.1 0.3 -1.8 -1.4 -1.9 -1.3 -1.8 -1.9 2.1
Medication: Lisinopril 1.1 1.4 7.4 -2.7 -1.1 1.5 -1.2 -1.2 -0.8 -0.0 -1.1 -0.9 -1.2 -1.0 0.9 1.0 -1.4 -0.8 -1.7 0.8 -1.2 -0.6 0.5 0.1 0.8 1.1 -0.4 -0.5 -1.2 -0.9 -1.1 -0.9 2.5
Medication: Atorvastatin 2.3 2.8 5.8 -0.4 -1.6 -1.6 -1.8 -1.1 -1.8 -1.2 -2.4 -0.6 -2.1 -1.8 1.9 2.0 -1.6 -2.2 -1.3 -1.5 -1.7 -1.7 -1.6 -1.5 -1.8 -1.9 -1.9 -0.2 -2.1 -1.9 -1.9 -1.8 1.1
Illnesses of father: High blood pressure 1.7 2.1 6.7 0.1 1.6 0.5 1.2 1.6 1.2 0.7 1.3 1.6 1.3 1.7 -1.2 -1.4 0.8 1.6 0.9 2.4 1.1 1.7 1.5 1.7 2.1 1.7 0.8 2.6 1.5 1.4 0.6 1.6 0.8
Alcohol drinker status: Never 0.4 0.5 3.2 -0.3 -0.5 -1.2 -0.0 -0.7 -0.1 -1.8 -1.1 -0.9 -0.3 -0.5 -0.3 0.4 0.3 -0.5 0.0 -0.6 0.1 -0.4 -1.0 -0.5 -0.9 -1.3 -0.6 -0.6 -0.2 -0.3 -0.0 -0.2 -0.9
Ever smoked 1.0 1.7 3.0 -0.9 -1.4 -0.5 -1.3 -1.4 -1.4 -0.4 -1.4 -0.8 -1.5 -1.4 1.3 1.4 -1.3 -1.6 -1.4 -1.5 -1.4 -1.2 -1.7 -1.3 -1.3 -1.2 -1.7 -0.7 -1.4 -1.4 -1.7 -1.5 0.4
Basal metabolic rate 0.6 3.6 28.8 -4.2 -0.9 1.9 -1.4 -0.4 -1.5 1.3 -0.8 1.0 -1.8 -1.1 1.4 1.6 -1.3 -1.2 -3.3 1.3 -1.3 0.3 1.1 0.8 0.6 2.4 0.9 1.6 -2.3 -1.4 -1.5 -1.0 5.4
Leg fat percentage (left) 0.3 1.2 2.7 -1.4 -1.4 1.1 -1.3 -1.2 -1.3 -0.7 -0.9 -1.4 -1.3 -1.4 1.6 1.4 -1.3 -1.1 -1.0 -0.4 -1.2 -1.0 -0.2 -0.7 -0.1 0.2 -0.8 -1.3 -1.3 -1.0 -0.8 -1.3 1.1
Arm fat-free mass (left) 0.5 2.6 23.1 -3.0 -0.3 2.0 -0.7 0.2 -0.7 1.6 0.0 1.5 -1.2 -0.3 0.8 0.9 -0.6 -0.6 -2.3 1.7 -0.6 0.7 1.7 1.2 1.1 2.8 1.3 2.1 -1.6 -0.5 -0.7 -0.4 4.8
Number of operations (self-reported) 0.6 1.0 2.4 -1.5 -1.2 1.3 -1.1 -0.1 -0.9 1.1 -0.6 -1.0 -1.1 -1.4 1.2 1.0 -0.7 -0.9 -1.2 0.1 -1.0 -0.8 0.3 -0.6 0.1 0.6 -0.5 -1.1 -1.2 -0.7 -0.7 -1.1 1.5
Average weekly beer plus cider intake 0.7 1.0 2.6 -0.8 -1.1 -0.1 -1.0 -1.1 -0.9 -1.3 -1.0 -0.9 -0.9 -1.1 1.1 1.1 -0.9 -1.0 -1.1 -1.1 -1.0 -1.1 -1.2 -1.6 -0.6 -0.9 -1.3 -0.7 -0.9 -1.2 -1.3 -1.0 0.1
Irritability 0.1 0.2 0.8 -0.3 -0.3 0.9 0.0 0.1 0.0 0.2 0.1 -0.2 -0.3 -0.1 0.5 0.1 0.1 -0.1 -0.2 0.4 0.1 0.0 0.8 0.5 0.8 0.7 0.6 -0.5 -0.3 0.1 0.4 0.1 0.6
Risk taking 0.2 0.3 1.5 -0.6 -0.4 1.2 -0.5 0.4 -0.6 -0.1 0.2 -0.3 -0.3 -0.6 1.0 0.2 -0.5 -0.2 -0.9 0.1 -0.6 -0.3 0.3 0.1 0.4 0.7 -0.4 0.2 -0.5 0.2 -0.5 -0.4 1.2
Ever had prostate specific antigen (PSA) test 0.8 0.9 5.9 0.3 -0.3 -1.5 -0.8 -0.1 -1.0 0.2 -1.5 0.4 -0.8 -0.4 0.4 0.8 -0.8 -1.0 -0.6 -1.5 -0.8 -0.6 -1.2 -0.6 -2.4 -1.6 -0.2 -0.0 -1.0 -1.0 -0.9 -0.7 0.1
Fractured/broken bones in last 5 years 0.8 1.0 3.4 -1.4 -1.2 1.2 -1.0 0.1 -1.1 1.2 -0.8 -1.0 -1.1 -1.2 1.8 1.3 -1.0 -0.9 -1.2 -0.3 -1.1 -0.8 -0.2 -0.7 0.0 0.4 -0.5 -0.7 -1.2 -0.7 -0.8 -1.0 1.4
Age started oral contraceptive pill 0.2 0.3 1.2 -0.2 0.5 0.3 0.5 1.1 0.7 0.9 0.2 0.4 0.6 0.5 -0.1 -0.6 0.4 0.8 0.1 0.5 0.3 0.5 0.5 0.9 0.4 0.1 0.6 -0.2 0.6 0.4 0.3 0.6 -0.3
Diastolic blood pressure, automated reading 0.3 1.0 4.5 -1.0 0.0 1.9 -0.1 0.2 -0.0 1.6 0.3 0.0 -0.0 0.1 0.1 0.2 -0.3 0.4 -0.9 1.6 -0.1 0.4 1.8 1.3 2.1 2.0 0.6 0.2 -0.1 0.4 0.1 0.3 1.9
Ever depressed for a whole week 0.3 0.4 0.8 -0.4 -0.7 0.2 -0.8 -0.9 -0.7 0.4 -0.5 -0.7 -0.8 -0.7 0.9 0.6 -0.7 -0.6 -0.7 -0.2 -0.7 -0.7 -0.2 -0.3 -0.1 0.0 -0.7 -0.8 -0.7 -0.6 -0.7 -0.8 0.4
Unable to work because of sickness or disability 0.3 0.4 1.2 -0.6 -0.6 0.4 -0.6 0.2 -0.6 0.3 0.1 -0.4 -0.7 -0.6 0.6 0.6 -0.5 -0.5 -0.8 0.5 -0.5 -0.2 0.0 -0.7 0.8 0.7 -1.1 0.7 -0.5 -0.2 -0.8 -0.4 1.1
Commuting to job workplace: Cycle 0.2 0.2 0.8 -0.2 -0.5 -0.8 -0.4 -0.3 -0.6 -0.5 -0.7 -0.3 -0.4 -0.5 0.6 0.5 -0.2 -0.6 -0.4 -0.5 -0.3 -0.4 -0.7 -0.1 -0.7 -0.9 -0.6 -0.4 -0.3 -0.4 -0.4 -0.3 -0.3
Myopia 0.4 0.6 1.3 0.0 0.8 -0.8 1.1 0.5 1.1 -0.6 0.5 0.4 0.9 1.0 -1.0 -0.8 1.1 0.7 0.9 0.4 1.1 1.1 -0.3 0.5 0.2 -0.3 0.5 1.0 1.0 0.6 0.4 0.9 -0.9
Vascular/heart problems diagnosed by doctor 0.7 1.8 4.7 0.8 -1.4 -0.3 -1.0 -0.8 -1.2 -0.5 -0.9 -1.7 -1.1 -1.5 1.2 1.2 -0.9 -1.4 -0.7 -2.1 -1.0 -1.9 -1.7 -2.2 -1.4 -1.7 -1.7 -2.0 -1.0 -1.0 -0.8 -1.4 -1.3
Cholesterol lowering medication 0.5 0.7 1.4 0.7 0.9 -0.5 1.1 1.0 0.8 0.6 0.6 0.8 0.9 0.9 -0.5 -1.0 1.0 0.9 1.2 1.1 1.0 1.0 0.8 0.7 0.6 0.5 0.9 0.9 0.9 0.7 1.1 1.0 -0.4
Medication: Omeprazole (e.g. Zanprol) 2.0 2.4 6.9 -1.6 -2.0 1.7 -1.6 -0.6 -1.8 -0.3 -1.4 -2.6 -1.6 -2.1 1.7 1.9 -1.7 -1.3 -2.1 -0.4 -1.6 -1.8 -0.9 -1.9 0.7 0.1 -1.8 -1.5 -1.3 -1.3 -1.4 -1.5 1.0
Pain experienced in last month 1.6 2.7 8.1 1.9 1.9 -1.4 2.1 1.8 1.7 0.1 1.1 1.0 2.2 1.8 -2.0 -2.1 2.0 1.9 2.1 0.6 2.0 1.4 -0.0 0.5 0.2 -0.9 0.9 0.8 2.4 1.4 1.6 2.0 -2.9
Supplements: Calcium 0.7 0.8 2.4 -1.4 -1.1 1.4 -0.8 -0.4 -0.6 0.4 -0.7 -1.1 -1.0 -1.0 1.5 1.0 -0.4 -0.8 -1.0 -0.1 -0.7 -0.7 -0.2 -0.8 0.2 0.6 -0.4 -0.9 -1.0 -0.7 -0.6 -1.0 1.1
Basal cell carcinoma (self-reported) 0.5 0.6 2.5 0.7 -0.5 -0.7 -0.5 -0.6 -0.7 -1.0 -0.9 -0.3 -0.6 -0.6 0.5 0.6 -0.4 -0.8 0.0 -1.2 -0.4 -0.7 -1.2 -1.1 -1.6 -1.2 -0.6 -0.3 -0.6 -0.5 -0.5 -0.8 -0.6
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.7 -1.2 -0.2 0.8 0.3 1.0 0.4 0.3 0.4 -0.9 0.1 -0.1 0.2 -0.3 0.3 0.3 0.3 0.8 0.3 0.2 0.2 0.3 1.3 0.4 -0.2 -0.3 0.3 -0.0 0.3 0.3 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 2.6 0.2 0.7 0.5 0.7 1.6 0.8 1.6 0.8 0.6 0.7 0.4 -0.5 -0.6 0.8 0.8 0.2 1.3 0.7 1.0 1.3 0.9 1.2 1.2 1.1 0.7 0.6 0.6 0.9 0.9 0.6
Heart disease (siblings) 0.8 1.0 5.6 -0.7 0.3 2.4 0.5 0.7 0.8 1.9 1.2 -0.1 0.6 0.5 -0.0 -0.4 0.3 1.0 -0.0 1.4 0.4 0.6 1.5 0.4 1.9 1.9 0.5 0.5 0.6 1.1 0.7 0.6 0.8
Alcohol drinker status: Previous 1.5 1.8 3.5 0.2 1.4 -0.5 1.6 1.4 1.9 0.4 1.4 0.5 1.6 1.5 -1.7 -1.8 1.5 1.6 1.0 1.5 1.5 1.6 0.6 1.1 1.5 0.5 0.7 1.0 1.9 1.1 1.0 1.7 -1.2
Pack years of smoking 1.7 2.5 6.5 -2.4 -1.7 2.2 -2.0 -0.0 -2.0 0.6 -1.1 -1.4 -1.6 -1.9 2.5 1.6 -1.8 -1.3 -2.3 -0.4 -1.9 -1.3 -0.2 -1.1 0.1 0.6 -1.4 -1.0 -1.8 -1.2 -1.8 -1.5 2.3
Impedance of whole body 0.2 0.8 6.1 0.7 0.5 -0.5 0.8 -0.3 0.9 -1.5 0.8 -0.9 1.1 0.6 -0.6 -0.9 0.7 0.9 1.5 -0.3 0.7 0.2 -0.3 -0.4 0.5 -0.8 -0.2 -1.3 1.4 0.4 0.8 0.7 -2.5
Leg fat mass (left) 0.7 2.7 9.2 -3.0 -1.7 1.9 -1.8 -1.4 -1.9 -0.1 -1.2 -1.2 -1.9 -1.8 2.1 2.0 -1.8 -1.5 -2.2 0.1 -1.8 -1.0 0.1 -0.4 0.4 1.1 -0.7 -0.8 -2.0 -1.5 -1.5 -1.6 3.0
Arm predicted mass (left) 0.5 2.8 24.1 -3.3 -0.3 2.2 -0.7 0.2 -0.7 1.5 0.0 1.4 -1.2 -0.3 0.8 1.0 -0.6 -0.6 -2.4 1.9 -0.6 0.7 1.8 1.2 1.3 2.9 1.4 2.0 -1.6 -0.6 -0.7 -0.4 4.9