Best TWAS P=1.25e-08 · Best GWAS P=5.06e-07 conditioned to 0.01
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | ZNF131 | 0.18 | 0.06 | lasso | 15 | 0.12 | 3.3e-15 | -3.9 | 5.2 | 2.2e-07 | 0.41 | 0.45 | 0.38 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MGC42105 | 0.04 | 0.01 | blup | 63 | 0.01 | 4.3e-02 | -3.8 | -5.7 | 1.2e-08 | -0.49 | 0.01 | 0.16 | TRUE |