[Hub]/) : Traits : Hip circumference :

chr5:12,225-1,135,834

Best TWAS P=3.28e-10 · Best GWAS P=1.72e-09 conditioned to 0.432

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SDHA 0.12 0.06 bslmm 290 0.11 8.6e-14 5.8 -5.8 9.0e-09 -0.86 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous SDHA 0.10 0.09 lasso 5 0.07 1.9e-06 6.0 5.7 1.2e-08 0.97 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum SDHA 0.10 0.05 lasso 3 0.07 1.5e-04 6.0 5.2 2.4e-07 0.90 0.02 0.95 FALSE
4 GTEx Adipose Visceral Omentum CCDC127 0.13 0.03 lasso 4 0.05 9.0e-04 5.3 5.4 7.9e-08 0.74 0.07 0.90 FALSE
5 GTEx Artery Aorta PDCD6 0.26 0.17 lasso 4 0.14 2.8e-08 6.0 -5.9 3.5e-09 -0.99 0.01 0.99 FALSE
6 GTEx Artery Tibial PDCD6 0.22 0.07 lasso 4 0.06 2.1e-05 6.0 -5.4 5.3e-08 -0.94 0.01 0.99 FALSE
7 GTEx Brain Frontal Cortex BA9 AHRR 0.32 0.21 lasso 4 0.18 1.6e-05 6.0 5.5 3.4e-08 0.93 0.01 0.91 FALSE
8 GTEx Cells Transformed fibroblasts SDHA 0.23 0.18 lasso 2 0.17 1.6e-12 6.0 6.0 2.0e-09 0.99 0.01 0.99 FALSE
9 GTEx Cells Transformed fibroblasts CTD-2083E4.5 0.09 0.07 lasso 3 0.05 1.2e-04 6.0 -5.7 1.2e-08 -0.99 0.01 0.97 FALSE
10 GTEx Heart Atrial Appendage SDHA 0.15 0.04 lasso 3 0.02 4.3e-02 5.3 -5.9 3.2e-09 -0.69 0.08 0.73 FALSE
11 GTEx Muscle Skeletal PDCD6 0.08 0.04 lasso 6 0.01 1.8e-02 5.8 -5.2 2.5e-07 -0.89 0.02 0.94 FALSE
12 GTEx Nerve Tibial CCDC127 0.05 0.01 lasso 4 0.02 2.2e-02 5.3 6.1 1.2e-09 0.86 0.04 0.83 FALSE
13 GTEx Thyroid CTD-2083E4.5 0.07 0.06 lasso 2 0.04 3.6e-04 6.0 -6.1 1.2e-09 -0.99 0.01 0.98 FALSE
14 GTEx Whole Blood SDHA 0.05 0.01 lasso 5 0.01 3.4e-02 4.8 -5.9 3.1e-09 -0.90 0.02 0.92 FALSE
15 METSIM Adipose SDHA 0.09 0.04 lasso 12 0.03 8.5e-06 5.8 5.3 1.1e-07 0.95 0.01 0.98 FALSE
16 NTR Blood CCDC127 0.02 0.01 blup 284 0.02 1.5e-06 1.1 -5.2 2.0e-07 -0.62 0.16 0.83 FALSE
17 YFS Blood PDCD6 0.03 0.03 bslmm 276 0.03 1.6e-09 6.0 6.3 3.3e-10 0.90 0.01 0.99 TRUE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDCD6 0.03 0.02 blup 49 0.02 2.9e-03 5.8 6.2 5.7e-10 0.95 0.02 0.96 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SDHA 0.04 0.03 blup 62 0.05 3.3e-06 6.0 5.6 2.5e-08 0.87 0.02 0.98 FALSE
20 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRRC14B 0.08 0.04 lasso 5 0.03 6.7e-03 5.8 5.8 5.0e-09 0.97 0.01 0.96 FALSE
21 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AHRR 0.11 0.05 lasso 3 0.07 2.5e-04 6.0 5.6 2.6e-08 0.86 0.01 0.93 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma PDCD6 0.07 0.06 enet 5 0.07 2.0e-07 6.0 -5.7 1.2e-08 -0.91 0.01 0.99 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma SDHA 0.06 0.09 lasso 13 0.08 1.8e-08 6.0 5.9 3.6e-09 0.99 0.01 0.99 FALSE