Best TWAS P=1.3e-12 · Best GWAS P=1.89e-16 conditioned to 2.07e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | FIG4 | 0.17 | 0.11 | lasso | 9 | 0.03 | 3.7e-02 | -4.7 | 5.1 | 3.1e-07 | 0.02 | 0.08 | 0.62 | FALSE |
| 2 | YFS | Blood | FOXO3 | 0.03 | 0.01 | lasso | 3 | 0.02 | 3.2e-07 | -7.0 | 7.1 | 1.3e-12 | -0.78 | 0.39 | 0.61 | TRUE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SMPD2 | 0.07 | 0.08 | blup | 45 | 0.07 | 2.3e-04 | -5.0 | -5.3 | 1.0e-07 | 0.01 | 0.01 | 0.96 | TRUE |