TWAS
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Traits
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Traits
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Hip circumference
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chr6:108,183,628-110,843,638
Best TWAS P=1.3e-12 · Best GWAS P=1.89e-16 conditioned to 2.07e-05
108.5M
109M
109.5M
110M
110.5M
111M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
FOXO3
0.03
0.01
lasso
3
0.02
3.2e-07
-7.0
7.1
1.3e-12
-0.78
0.39
0.61
TRUE
3
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
SMPD2
0.07
0.08
blup
45
0.07
2.3e-04
-5.0
-5.3
1.0e-07
0.01
0.01
0.96
TRUE
1
GTEx
Colon Sigmoid
FIG4
0.17
0.11
lasso
9
0.03
3.7e-02
-4.7
5.1
3.1e-07
0.02
0.08
0.62
FALSE