Hub : Genes

FIG4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2430	0.0480	0.0e+00	0.200	0.177	0.205	0.169	0.204	8.9e-24	5.4e-21	1.8e-24	5.0e-20	2.4e-24
2	GTEx	Adipose Subcutaneous	0.1210	0.0420	8.2e-05	0.081	NA	0.048	NA	0.066	3.5e-07	NA	8.5e-05	NA	4.4e-06
3	GTEx	Artery Tibial	0.1825	0.0546	3.7e-06	0.012	NA	0.069	NA	0.034	3.5e-02	NA	4.1e-06	NA	1.1e-03
4	GTEx	Cells Transformed fibroblasts	0.1300	0.0420	1.5e-06	0.121	NA	0.085	NA	0.113	2.3e-09	NA	6.5e-07	NA	8.3e-09
5	GTEx	Colon Sigmoid	0.1660	0.0730	2.1e-03	0.109	NA	0.010	NA	0.028	1.2e-04	NA	1.4e-01	NA	3.7e-02
6	GTEx	Esophagus Muscularis	0.1400	0.0530	1.5e-04	0.017	NA	0.028	NA	0.020	3.0e-02	NA	7.9e-03	NA	2.0e-02
7	GTEx	Muscle Skeletal	0.2025	0.0535	2.8e-08	0.112	NA	0.111	NA	0.105	4.2e-11	NA	4.8e-11	NA	1.7e-10
8	METSIM	Adipose	0.0595	0.0266	1.9e-03	-0.001	0.010	0.006	0.011	-0.001	4.9e-01	9.7e-03	4.3e-02	7.1e-03	4.7e-01
9	ROSMAP	Brain Pre-frontal Cortex	0.1430	0.0394	2.7e-13	0.132	0.127	0.132	0.133	0.136	1.3e-16	5.8e-16	1.2e-16	8.7e-17	3.8e-17
10	YFS	Blood	0.0425	0.0123	1.0e-12	0.037	0.041	0.039	0.039	0.037	2.7e-12	2.7e-13	9.3e-13	8.4e-13	2.4e-12
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0724	0.0353	2.1e-03	0.019	0.032	0.032	NA	0.036	2.6e-03	1.4e-04	1.4e-04	NA	5.5e-05
12	TCGA	Brain Lower Grade Glioma	0.0459	0.0238	1.7e-04	0.015	0.023	0.020	NA	0.011	6.8e-03	1.0e-03	2.3e-03	NA	1.7e-02
13	TCGA	Thyroid Carcinoma	0.0810	0.0330	7.0e-07	0.057	0.073	0.080	NA	0.080	3.2e-06	1.4e-07	3.2e-08	NA	3.2e-08
14	TCGA	Uterine Corpus Endometrial Carcinoma	0.2430	0.1140	5.6e-03	0.052	-0.001	0.007	NA	0.002	1.4e-02	3.3e-01	2.0e-01	NA	2.9e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.3	0.5	2.1	0.3	-1.1	1.4	-0.2	0.0	0.2	0.1	-0.1	-0.1	-0.0	-0.4	-0.3	-0.8	1.5
Bipolar Disorder or Schizophrenia	0.2	0.5	2.6	0.2	-1.1	0.5	0.1	-0.5	-0.2	0.7	-1.6	-0.2	-0.7	-0.4	-0.7	-1.2	0.6
Depressed Affect (Nagel 2018)	0.7	1.4	3.4	-1.4	0.8	1.2	1.8	-1.1	-0.9	-0.3	0.0	-1.3	-1.6	0.9	-1.5	-1.6	-0.5
Depression (Nagel 2018)	0.6	0.9	2.5	-0.5	0.8	1.6	1.5	-0.8	-0.3	-0.5	0.9	-0.8	-0.9	1.0	-0.9	-1.4	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.3	-0.4	-0.1	0.5	0.9	-1.1	-1.0	-1.0	1.2	-0.6	-0.9	-0.4	-0.6	-1.0	0.2
Neuroticism (Nagel 2018)	0.8	1.8	5.5	-1.2	0.2	-0.1	2.4	-1.6	-1.2	-0.9	-0.0	-1.3	-1.7	0.3	-1.7	-2.2	0.4
Schizophrenia (2018)	0.3	0.6	3.9	0.0	-0.5	-0.5	0.3	-0.7	-0.4	0.8	-2.0	-0.2	-0.9	-0.2	-0.6	-0.8	-0.4
Schizophrenia vs Biploar Disorder	0.9	1.1	3.3	1.1	0.0	-0.5	-1.3	1.1	1.0	1.1	-0.9	0.9	1.4	-0.1	0.9	1.8	-1.3
Worry (Nagel 2018)	0.3	0.6	2.2	0.4	0.5	0.1	1.3	0.1	0.4	-0.8	0.1	0.3	-0.5	0.9	-0.2	-1.1	1.5
Alzheimer’s Disease (in mother)	0.6	0.7	2.4	-0.5	-0.4	0.9	0.4	-1.1	-0.7	-0.5	0.3	-0.4	-0.9	-0.5	-0.7	-1.5	-1.3
Alzheimer’s Disease (in father)	0.2	0.2	1.0	-0.3	0.1	0.5	0.2	-0.0	-0.3	-0.0	0.3	-0.1	-0.8	0.0	0.1	-0.7	-1.0
Alzheimer’s Disease (including proxy)	1.3	2.0	4.2	-1.6	-0.3	0.5	1.4	-1.7	-1.8	-0.9	0.3	-1.6	-1.8	-0.4	-1.5	-2.0	-1.7
Crohns Disease (2017)	0.6	1.3	3.5	1.9	-0.1	-0.1	-1.0	0.7	1.6	0.9	0.0	1.7	1.7	-0.2	1.3	1.1	0.5
Irritable Bowel Disease (IBD)	1.4	3.3	6.9	2.6	-0.7	2.4	-2.1	1.3	2.3	1.8	0.4	2.4	2.3	-0.2	2.1	1.8	0.2
Ulcerative Colitis (UC)	1.5	2.7	10.7	1.8	-1.0	3.3	-2.2	1.2	1.6	1.7	0.3	1.7	1.7	-0.4	1.6	1.6	-0.4
Major Depression (MDD)	0.9	1.1	3.6	-0.6	-0.6	0.3	1.9	-1.0	-0.7	-0.7	-0.5	-1.4	-0.8	0.6	-1.6	-1.7	0.6
Reaction Time	0.4	0.7	2.4	-0.3	-1.5	0.9	0.6	-0.9	-0.1	0.5	-0.9	-1.1	0.1	0.2	-0.9	-1.4	0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.4	0.9	-0.7	-0.5	0.4	0.3	-0.6	-0.6	-0.9	0.8	-0.9	-0.1	-0.2	-0.7	-0.5	0.1
Breast Cancer	0.9	2.2	5.2	-1.6	-0.0	-2.1	1.2	-2.3	-1.9	0.2	-1.3	-1.9	-0.5	-0.9	-1.8	-1.1	-1.9
Ovarian Cancer	0.6	0.7	2.4	0.7	1.3	0.4	0.4	0.4	0.8	-0.4	0.8	0.6	-0.8	1.1	0.9	0.8	1.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	2.7	4.0	8.2	-2.4	-0.7	-1.1	1.7	-2.4	-2.9	-1.9	-0.1	-2.4	-2.5	-1.4	-2.1	-2.9	-0.8
Bipolar Disorder (2011)	1.8	1.7	5.4	-0.0	-2.1	1.0	0.6	-2.3	-1.2	-0.0	-0.3	-0.6	-0.8	-1.9	-1.2	-1.8	1.4
Body Mass Index (BMI) (2010)	2.2	3.0	8.8	1.1	1.5	2.5	-1.3	2.4	2.1	0.9	-0.1	1.3	2.1	1.7	1.5	3.0	0.2
Coronary Artery Disease (CAD)	0.4	0.5	1.8	0.1	0.8	0.6	0.1	1.0	0.4	-1.3	-0.1	0.3	-0.2	0.7	0.4	0.6	1.3
Crohns Disease (2012)	0.3	0.5	2.1	1.4	-0.3	-0.2	-0.3	-0.1	0.8	0.2	-0.6	1.2	0.6	-0.5	0.6	0.4	0.8
Mean Putamen Volume	1.0	1.1	3.5	0.0	0.5	0.9	1.7	-0.7	-0.2	-1.7	0.1	-0.3	-1.7	0.8	-0.5	-1.9	1.0
Fasting Glucose	0.4	0.4	1.5	0.2	1.2	-1.0	0.4	0.1	0.1	-0.7	-1.2	0.5	0.3	0.4	-0.1	0.5	-1.0
HbA1C	0.7	0.8	3.9	0.5	0.9	-0.8	0.7	-0.3	-0.2	-1.7	-2.0	0.7	-0.4	-0.4	-0.0	0.7	-0.1
HDL Cholesterol	0.6	1.0	5.3	0.6	-0.4	0.4	-0.8	1.6	1.0	0.3	2.3	0.6	1.4	0.9	0.4	0.4	0.3
LDL Cholesterol	2.3	3.7	8.7	-1.8	-1.0	-0.6	2.7	-3.0	-2.4	-0.8	-1.4	-2.4	-1.7	-0.7	-2.8	-2.4	-0.6
Lupus	0.4	0.6	3.3	0.0	-1.5	-0.4	-0.9	-0.7	-0.7	-0.2	-0.3	-0.3	0.6	-1.8	-0.1	0.2	0.0
Neuroticism (2016)	1.8	2.7	7.3	-2.3	-0.8	-2.7	1.3	-2.1	-2.4	-0.2	-0.7	-1.9	-0.8	-1.3	-2.0	-1.2	-0.7
Primary Biliary Cirrhosis	1.1	1.6	3.5	-1.1	0.1	-1.2	1.9	-1.7	-1.5	-1.1	-0.5	-1.5	-1.2	-0.2	-1.6	-1.4	-0.7
Rheumatoid Arthritis	2.3	3.1	7.3	2.7	0.1	1.1	-1.4	2.4	2.4	-0.2	0.9	2.5	0.6	0.9	2.4	1.3	2.5
Schizophrenia (2014)	0.6	1.3	5.1	-0.2	-1.5	-0.9	0.1	-1.5	-1.0	0.9	-2.3	-0.6	-0.6	-1.4	-0.8	-1.1	-0.9
Triglycerides	1.4	2.4	6.1	-1.6	0.1	-1.9	1.8	-2.5	-2.1	-1.3	-0.9	-1.6	-1.2	-1.0	-1.9	-1.2	-0.9
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.3	0.1	0.5	1.2	0.2	0.3	0.4	-0.6	-0.1	0.2	0.8	0.1	0.2	0.6	-0.4
Ulcerative Colitis	0.8	1.1	6.5	1.3	-0.8	2.5	-1.3	0.2	0.7	0.8	-0.2	1.1	0.8	-0.7	0.9	1.0	0.1
Blood Eosinophil Count	2.2	16.8	44.1	-4.3	-3.5	-4.5	2.6	-6.6	-5.6	-2.9	-2.1	-4.9	-1.9	-4.1	-5.1	-3.9	-1.7
Blood Platelet Count	1.6	18.5	50.0	-3.3	-7.1	-5.8	-0.9	-6.5	-4.7	0.1	-0.8	-4.5	3.5	-6.2	-4.4	-2.0	-2.0
Blood Red Count	3.4	32.4	136.9	1.1	8.6	1.7	6.7	1.9	0.6	-11.7	-6.7	2.7	-10.3	4.6	-0.4	-3.0	0.1
Blood White Count	0.8	5.9	22.6	-1.5	-3.4	-4.7	0.8	-3.7	-2.7	0.3	-0.8	-2.3	1.4	-2.9	-2.5	-1.2	0.3
Heel T-Score	0.9	7.0	22.8	-1.7	4.8	1.5	3.3	1.4	0.1	-4.2	-1.3	-0.9	-4.0	4.2	-0.9	-1.7	-0.7
BMI	0.7	4.1	14.4	1.4	2.4	3.5	1.0	2.3	2.6	-1.3	-0.1	1.1	0.1	3.8	1.3	0.3	2.1
Height	5.2	99.9	196.0	10.4	8.4	8.4	-5.8	14.0	12.3	3.5	12.5	12.9	5.7	8.3	12.8	11.0	6.8
Waist Hip Ratio (WHR)	0.4	1.9	6.3	-0.9	0.8	1.5	2.5	-1.6	-1.0	-2.0	-0.2	-0.5	-2.2	0.6	-1.4	-1.4	0.4
Systolic Blood Pressure	0.8	4.0	8.5	2.6	2.4	1.5	0.4	2.6	2.9	-1.3	-0.6	2.3	1.0	2.9	1.5	2.0	1.6
Smoking Status	0.4	1.1	3.1	-0.3	-1.8	-0.6	0.0	-1.4	-0.8	1.2	-1.2	-1.1	0.5	-1.3	-0.8	-1.3	0.1
Allergy or Eczema	0.2	0.6	1.8	1.1	-0.6	1.0	-0.5	-0.5	0.1	-0.6	0.1	1.3	-0.9	-1.3	0.8	-0.3	-0.5
Cardiovascular Disease	2.0	6.7	17.0	2.9	3.8	1.9	1.4	2.6	3.3	-2.0	1.6	3.0	-0.3	4.1	1.8	1.4	3.2
Hypothyroidism (self reported)	2.9	6.7	14.7	-3.2	-0.5	-2.4	2.6	-2.4	-3.1	-1.8	-3.6	-3.4	-1.4	-0.7	-3.8	-2.1	-2.5
Respiratory disease	1.6	3.6	10.6	-1.5	-2.1	-1.0	1.6	-3.2	-2.2	-0.6	-1.2	-2.1	-0.9	-1.7	-2.5	-2.9	-1.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.4	0.6	0.5	1.2	0.0	0.5	0.9	1.2	0.5	0.4	1.0	1.1	0.2	0.8	0.3
Lung FEV1/FVC ratio	0.9	4.5	23.3	-0.8	4.8	1.5	1.4	2.8	1.1	-1.9	1.3	0.4	-1.6	3.8	1.1	1.6	0.3
Lung FVC	1.9	9.9	24.2	2.3	0.9	3.2	-3.6	4.9	3.7	3.3	2.5	3.0	3.2	1.8	4.1	3.5	1.4
Neuroticism	0.5	1.1	3.3	-1.0	0.1	-0.3	1.6	-1.8	-1.4	-0.6	0.0	-0.9	-1.3	-0.5	-1.4	-1.0	0.3
Chronotype (morning person)	1.0	2.4	6.0	1.6	2.2	1.2	-0.3	2.1	2.0	-1.0	1.6	2.4	0.1	1.7	1.8	0.9	-0.0
Hair Pigment	0.0	0.8	3.4	-0.0	0.9	0.4	1.0	-0.5	-0.8	-1.6	-0.8	0.3	-1.8	-0.2	0.0	0.4	1.1
Tanning	0.1	1.2	3.8	0.6	-1.5	0.8	-2.0	1.2	0.8	1.0	0.8	0.4	1.6	-0.5	1.2	0.9	0.2
Hand grip strength (left)	2.3	6.0	13.0	2.2	2.8	3.6	0.1	2.4	2.7	-1.4	3.4	2.7	-0.7	3.0	2.5	0.9	2.7
Number of treatments/medications taken	0.4	0.7	1.8	1.0	1.0	1.2	0.7	0.7	0.9	-0.5	0.5	0.8	-0.7	1.4	0.3	0.3	1.3
Average weekly spirits intake	0.4	0.5	1.7	-0.1	0.9	-0.3	1.2	-0.2	-0.2	-0.5	0.2	0.2	-1.3	0.9	-0.7	-0.6	-0.9
Sensitivity / hurt feelings	1.4	2.4	5.6	-1.6	-1.4	-0.8	1.4	-2.4	-2.1	-0.7	-1.1	-1.9	-1.2	-1.2	-2.4	-1.7	0.1
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.2	-1.2	0.9	-0.3	2.0	-1.1	-1.1	-1.4	0.9	-1.1	-1.7	0.6	-1.7	-2.1	-0.5
Hearing difficulty/problems: Yes	2.2	3.4	7.2	-2.0	0.3	-1.6	2.7	-2.4	-2.2	-2.1	-0.3	-1.8	-1.2	-0.4	-2.6	-2.0	-1.6
Relative age of first facial hair	0.4	0.9	4.5	-0.4	0.6	0.1	1.0	-0.6	-0.7	-0.6	2.1	-0.3	-1.8	0.2	-0.2	-1.3	0.6
Other serious medical condition/disability diagnosed by doctor	2.6	3.4	6.7	-2.3	-0.4	-1.2	1.7	-1.7	-2.1	-1.5	-0.9	-2.4	-1.9	-0.3	-2.6	-2.5	-2.1
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.4	-1.3	-0.6	-0.1	-0.3	-0.3	-1.3	0.1	1.5	-0.5	-0.9	-1.3	-0.4	-0.4	-1.3
Ever had hysterectomy (womb removed)	1.3	1.4	3.8	-1.0	-1.6	-1.9	-1.4	-0.3	-1.0	1.7	0.1	-0.7	0.4	-1.9	-0.2	0.4	-1.5
Systolic blood pressure, automated reading	0.9	2.6	8.5	1.4	2.9	0.5	1.1	2.3	1.9	-1.9	-0.5	1.6	-0.1	2.8	0.7	0.9	0.0
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	8.9	0.4	-0.4	1.7	-1.7	1.3	1.3	3.0	0.3	0.1	1.7	0.4	1.2	1.3	0.7
Angina	0.7	0.9	3.5	-1.1	-0.4	-1.5	0.2	-0.4	-1.1	-0.6	-1.9	-1.2	-0.3	-0.7	-1.2	-0.3	-0.8
Medication for hormone replacement therapy	2.0	2.2	7.8	-1.0	-2.1	-1.4	0.2	-2.4	-2.2	-0.2	0.4	-1.1	-0.4	-2.8	-1.4	-1.1	-0.4
Vitamin and mineral supplements	0.7	0.9	2.9	-0.5	0.9	0.5	-1.1	1.5	0.6	1.5	-0.4	-0.3	1.1	1.2	0.5	1.7	0.3
Supplements: Zinc	0.7	0.7	2.0	-0.7	-0.4	-0.6	0.8	-1.4	-1.2	-0.5	1.0	-0.5	-1.0	-0.8	-1.1	-0.8	-0.3
Medication: Co-codamol	0.7	0.8	3.9	-0.6	1.5	0.2	0.9	0.4	0.0	0.6	-0.2	-0.6	-0.3	1.7	-0.4	-0.6	-2.0
Medication: Metformin	0.3	0.4	1.6	0.4	-0.5	1.0	-0.4	0.3	0.7	1.3	0.1	-0.2	0.8	0.6	0.0	-0.1	0.5
Diabetes (father)	0.3	0.4	1.7	0.0	0.9	1.3	0.1	0.8	0.4	-0.5	0.1	-0.2	0.2	1.2	-0.1	0.4	0.1
Diabetes (mother)	2.5	3.2	7.7	1.9	0.7	1.2	-1.5	2.4	2.2	1.6	0.8	1.9	2.8	1.0	1.9	2.5	1.3
Severe depression (siblings)	1.5	1.7	3.9	-1.6	0.8	-1.0	1.6	-1.1	-1.4	-0.7	1.0	-1.5	-2.0	0.4	-1.7	-1.5	-0.8
Pack years adult smoking proportion	0.6	0.9	2.7	0.6	0.2	1.6	-0.6	0.9	1.1	0.1	-1.6	0.4	1.6	0.5	0.4	1.0	-0.1
Impedance of leg (right)	1.6	7.8	16.6	-2.6	-2.7	-3.0	2.2	-4.1	-3.5	-1.0	-1.9	-3.6	-1.5	-2.5	-3.7	-3.3	-1.6
Leg fat-free mass (left)	5.8	30.8	66.9	5.4	6.0	5.7	-2.1	8.2	7.1	0.8	5.6	6.9	1.8	6.3	6.5	5.2	4.3
Trunk fat percentage	0.9	3.4	14.4	0.8	2.5	3.0	1.0	2.6	2.2	-1.4	0.7	0.6	-0.1	3.8	1.0	0.2	1.4
Hand grip strength (right)	3.6	9.8	16.2	3.1	3.1	4.0	-1.2	3.6	3.7	-0.1	4.0	3.7	0.3	3.2	3.8	2.6	3.7
Townsend deprivation index at recruitment	0.6	0.8	2.2	1.4	-0.0	1.0	-0.9	1.0	1.0	0.1	0.0	1.5	0.6	-0.3	1.3	0.9	0.1
Current tobacco smoking	0.3	0.5	2.0	-0.3	-1.4	0.1	-0.3	-0.6	-0.3	1.0	-0.7	-0.6	1.1	-0.9	-0.3	-0.7	0.1
Average weekly fortified wine intake	2.3	2.7	7.0	-2.0	0.2	-0.1	2.6	-1.8	-1.9	-0.9	-0.7	-2.3	-1.8	0.5	-2.3	-2.0	-0.8
Maternal smoking around birth	0.3	0.5	2.7	0.2	0.8	1.3	0.9	-0.2	-0.0	-0.5	0.1	0.6	-1.7	0.5	-0.3	-0.3	0.0
Fed-up feelings	0.2	0.5	1.3	-0.7	0.1	0.6	0.9	-0.7	-0.6	-1.0	0.1	-0.4	-1.1	-0.1	-0.8	-1.0	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.0	-1.2	1.2	1.7	0.7	0.1	-0.3	0.9	0.8	-1.2	-0.9	1.4	-0.8	-1.1	-1.2
Relative age voice broke	0.9	1.4	4.6	-0.6	0.2	0.0	1.3	-1.0	-0.9	-1.6	2.1	-0.6	-1.6	-0.0	-0.7	-1.2	1.7
Taking other prescription medications	0.3	0.4	1.4	-0.3	0.6	0.6	1.2	-0.5	-0.2	-0.4	-0.3	-0.4	-1.1	0.6	-0.6	-0.8	-0.3
Age when periods started (menarche)	3.2	7.7	14.8	2.6	1.9	3.6	-2.3	3.8	3.8	1.3	2.5	3.1	1.4	2.5	3.9	2.5	2.0
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.7	-0.2	0.1	-0.9	-0.4	0.1	-0.1	0.5	0.2	0.1	-0.2	-0.2	0.3	0.5	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	6.4	-2.5	1.6	0.7	1.6	-0.2	-1.2	-1.2	0.0	-2.3	-2.5	1.7	-1.3	-1.2	-1.0
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.0	-1.3	-0.2	0.1	1.7	-1.7	-1.2	-1.2	-1.5	-1.5	-1.5	0.0	-1.5	-1.7	0.1
Qualifications: CSEs or equivalent	0.5	0.7	2.4	0.4	0.4	1.2	-0.7	1.2	0.7	-0.1	-0.5	1.0	0.9	0.1	0.7	1.5	-0.6
Serious illness, injury or assault to yourself	0.6	0.8	2.5	-1.3	-0.1	1.2	-0.1	-0.0	-0.4	0.7	-1.0	-1.3	-0.7	0.4	-0.9	-0.7	-1.6
High blood pressure	2.0	5.6	18.4	2.1	4.1	1.9	1.4	2.4	2.9	-1.8	0.6	2.2	-0.6	4.3	1.3	1.8	2.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.2	1.0	-0.8	1.0	-0.8	-0.4	0.3	0.3	-0.3	0.9	0.1	-1.1	0.9	0.1	-0.5
Multivitamins +/- minerals	0.6	0.8	2.4	0.1	-1.2	-0.3	0.6	-1.4	-0.8	-1.1	0.2	0.2	-0.8	-1.6	-0.3	-1.3	0.2
Stomach or abdominal pain in last month	1.3	1.6	4.0	-1.4	-0.5	-2.0	0.5	-1.1	-1.5	0.8	-1.5	-1.4	-0.8	-1.0	-1.3	-1.2	-1.7
Supplements: Glucosamine	2.9	3.7	10.5	-1.6	-0.4	-0.4	2.2	-2.4	-2.4	-1.0	-1.9	-1.5	-3.2	-0.9	-2.4	-2.4	-1.7
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.9	-0.4	-0.2	-0.3	0.6	-0.8	-0.6	0.0	0.0	-0.4	-0.2	-0.5	-0.9	-0.8	0.1
Medication: Atenolol	1.9	2.4	6.4	1.2	2.4	0.4	-0.2	2.5	1.9	-0.5	0.5	1.6	0.2	2.2	1.4	2.0	1.4
Medication: Levothyroxine sodium	1.4	2.3	4.8	-2.0	-0.2	-1.3	1.7	-1.4	-1.9	-0.8	-1.5	-1.9	-0.7	-0.6	-2.2	-1.1	-2.2
Sitting height	8.2	58.0	110.2	7.7	6.2	4.9	-5.6	10.5	9.0	5.0	9.9	9.8	4.3	5.5	10.0	8.8	4.7
Chronic bronchitis/emphysema (father)	0.5	0.6	2.4	0.2	-1.3	-0.4	-0.5	-0.5	-0.5	0.0	0.2	0.3	-0.6	-1.5	0.1	-1.5	-0.0
High blood pressure (mother)	0.6	0.8	3.2	-0.1	-1.8	-0.4	-0.7	-0.5	-0.3	0.9	-1.6	-0.6	1.4	-1.2	-0.6	-0.3	-0.2
Body mass index (BMI)	1.3	5.5	17.2	1.8	2.6	4.2	0.1	3.2	3.1	-1.1	0.9	1.9	0.1	3.7	2.1	1.1	2.1
Impedance of leg (left)	1.7	8.0	17.0	-2.7	-2.7	-3.1	2.4	-4.1	-3.5	-1.0	-1.8	-3.7	-1.6	-2.3	-3.7	-3.4	-1.4
Leg predicted mass (left)	5.8	30.5	66.3	5.4	6.0	5.8	-2.0	8.1	7.0	0.8	5.6	6.9	1.7	6.3	6.5	5.1	4.3
Trunk fat mass	2.4	10.2	25.2	2.8	3.7	4.6	0.0	4.6	4.3	-0.7	2.4	2.9	0.5	5.0	3.1	1.8	2.8
Waist circumference	1.8	6.6	20.6	2.2	2.6	4.5	-0.4	3.6	3.4	-0.1	1.5	2.5	0.6	3.6	2.6	2.0	1.8
Number of incorrect matches in round	0.2	0.3	2.3	0.4	-0.1	-0.2	0.6	-0.2	-0.1	-0.5	0.2	0.5	-1.5	0.0	-0.5	-1.0	0.5
Past tobacco smoking	0.9	1.7	4.6	0.9	0.2	1.5	-1.3	2.1	1.8	1.0	0.8	1.0	1.6	1.1	1.3	1.5	0.2
Alcohol usually taken with meals	1.3	2.0	4.1	-1.2	-0.6	-2.0	1.3	-2.0	-1.6	-1.5	-1.5	-1.7	-0.8	-0.6	-1.7	-1.5	-0.8
Nervous feelings	0.3	0.6	3.0	0.0	-0.5	-1.0	1.0	-0.5	-0.2	-0.3	-1.2	-0.2	-0.5	-0.2	-0.7	-1.7	0.6
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	7.0	-1.5	-0.0	-1.1	1.8	-1.6	-1.5	0.4	-0.3	-1.6	-2.0	-0.1	-2.3	-2.6	-0.5
Hearing difficulty/problems with background noise	2.8	4.6	10.3	-2.5	0.5	-1.7	3.0	-2.5	-2.5	-1.6	0.3	-2.3	-1.8	0.1	-2.9	-3.2	-1.7
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	0.8	0.5	0.4	0.1	0.9	0.9	0.4	0.9	0.6	1.0	1.0	0.0	0.6	0.6
Had menopause	0.9	1.1	3.5	0.6	1.1	1.7	-0.6	1.9	1.0	1.0	1.1	0.9	-0.2	1.0	1.1	0.8	0.3
Had other major operations	1.9	2.3	5.5	-1.0	-1.1	-1.7	1.7	-1.8	-1.7	-0.8	-1.5	-1.6	-1.3	-0.9	-2.0	-2.4	-0.8
Forced vital capacity (FVC)	5.2	20.2	47.3	4.6	3.1	3.9	-3.4	6.9	5.6	3.1	5.1	5.8	2.9	3.4	6.0	4.0	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	5.9	-2.1	1.6	0.6	1.1	0.2	-0.8	-0.6	0.3	-1.8	-2.4	1.7	-0.9	-0.8	-1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	2.2	-0.1	-0.8	0.3	-0.1	-0.6	-0.3	1.5	0.8	-0.3	-0.5	-0.5	-0.5	-0.6	-1.0
Qualifications: None of the above	0.7	1.5	5.1	0.8	1.3	2.3	-0.7	1.9	1.4	1.1	0.1	1.4	-0.2	1.1	1.4	0.4	-0.5
Financial difficulties in last 2 years	0.3	0.3	1.0	0.5	0.3	1.0	-0.3	0.9	0.9	-0.0	0.6	0.5	0.1	0.8	0.6	0.3	0.2
Mouth/teeth dental problems	1.1	1.6	4.2	0.8	-0.6	-0.4	-2.0	0.7	0.7	1.3	0.7	1.1	1.7	-1.4	1.8	1.9	1.0
Heart attack	0.9	1.2	5.6	-0.9	-0.2	0.1	0.9	-1.5	-1.2	-0.7	-2.4	-1.1	-1.3	-0.5	-1.2	-0.8	-0.2
Allergy	0.7	1.5	5.4	-1.1	2.3	-1.8	1.1	1.3	-0.0	-1.5	0.5	-0.5	-0.4	1.9	-0.4	0.9	0.8
Pain all over the body in last month	1.2	1.3	3.5	1.9	0.4	0.7	-0.3	1.4	1.6	0.8	1.2	1.8	0.1	1.0	1.1	0.4	1.2
Diabetes (self-reported)	0.5	0.7	2.7	0.3	0.6	1.4	-0.5	0.6	0.9	1.6	0.7	-0.1	1.0	1.3	0.1	0.8	0.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	4.6	1.0	-0.1	1.3	0.8	0.3	0.4	-2.2	-0.6	1.2	-0.4	0.3	0.5	0.4	1.5
Medication: Ramipril	1.1	1.5	5.1	0.7	2.2	-0.2	1.4	0.8	0.8	-2.3	1.0	1.1	-1.0	1.8	-0.0	-0.7	0.2
Medication: Simvastatin	1.2	1.7	6.6	-0.4	1.0	0.5	2.2	-1.3	-0.6	-2.6	-0.3	-0.9	-1.5	1.1	-1.3	-0.8	1.5
Fluid intelligence score	0.1	0.2	1.3	-0.2	-0.5	1.1	-0.2	-0.7	-0.2	-0.3	0.5	-0.5	-0.2	-0.4	-0.0	-0.1	0.6
Illnesses of siblings	0.2	0.4	0.9	0.6	-0.7	0.1	-0.2	-0.9	0.0	-0.1	-0.9	0.2	0.4	-1.0	0.1	-0.4	0.9
Neuroticism score	1.3	2.7	7.1	-1.6	0.5	-1.1	2.7	-2.1	-1.7	-1.4	-0.6	-1.6	-2.2	0.2	-2.3	-2.0	0.0
Weight	4.8	23.7	48.4	4.8	5.2	6.2	-1.2	7.0	6.4	0.2	4.4	5.7	1.2	6.0	5.6	3.8	4.1
Impedance of arm (right)	1.4	6.7	12.2	-2.7	-2.8	-3.1	0.3	-3.4	-3.0	0.8	-2.6	-3.5	0.3	-2.8	-2.9	-1.7	-3.1
Arm fat percentage (right)	0.4	1.6	6.7	0.4	1.1	2.6	0.6	1.5	1.6	-1.0	-0.4	-0.0	0.3	2.6	0.4	-0.2	1.0
Trunk fat-free mass	6.1	35.2	69.1	6.4	5.7	6.2	-2.6	8.3	7.6	1.7	6.3	8.0	1.8	5.8	7.3	5.2	4.8
Hip circumference	2.7	11.5	26.2	3.4	3.4	3.8	-1.3	5.1	4.7	0.6	2.6	3.8	1.8	4.2	4.0	3.1	2.3
Time employed in main current job	1.1	1.3	3.3	1.2	1.5	-0.7	0.5	1.5	1.5	-1.8	-0.1	1.1	0.4	1.6	0.7	0.7	1.0
Alcohol intake versus 10 years previously	1.9	2.9	6.8	1.5	2.6	2.5	0.0	2.0	1.8	-0.8	1.1	2.0	-0.5	2.1	2.0	1.4	1.3
Father’s age at death	0.7	1.0	2.5	-0.9	-1.0	-1.6	0.0	-1.1	-1.3	0.7	-1.0	-0.9	0.2	-1.2	-1.1	-0.1	-1.3
Worrier / anxious feelings	0.3	0.6	1.8	-0.7	0.0	-1.3	1.3	-1.0	-0.8	-0.9	-0.1	-0.4	-0.5	-0.2	-1.2	-0.8	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	4.4	0.6	-0.2	-0.9	1.9	-2.1	-0.6	-0.6	-1.6	-0.1	-0.7	-0.3	-1.8	-1.0	-0.1
Falls in the last year	1.0	1.4	3.6	-0.4	-1.7	-0.5	-0.5	-1.5	-1.0	1.4	-1.9	-0.7	-0.3	-1.9	-0.7	-0.9	-1.3
Hair/balding pattern: Pattern 3	1.3	1.9	7.7	-1.4	-1.1	-1.3	-0.2	-1.7	-1.6	0.3	-1.6	-1.4	0.7	-1.7	-1.0	-0.5	-2.8
Number of live births	0.4	0.6	2.2	-0.7	0.7	-0.6	1.5	-0.3	-0.4	0.3	0.4	-0.8	-0.8	0.9	-1.2	-0.9	-0.0
Forced expiratory volume in 1-second (FEV1)	5.4	18.4	49.6	3.7	3.6	4.1	-3.2	7.0	5.2	2.5	4.6	5.0	2.5	3.7	5.8	4.2	1.6
Pulse rate	0.5	0.8	4.0	1.9	0.9	0.2	0.4	0.4	1.1	0.2	0.4	2.0	0.0	0.6	0.9	0.0	0.5
Happiness	4.5	5.5	11.6	-3.4	0.5	-2.2	2.7	-2.6	-3.0	-1.0	0.4	-3.2	-2.7	-0.0	-3.1	-2.5	-1.9
Noisy workplace	0.3	0.3	1.5	0.1	1.2	0.7	0.4	0.1	0.1	-1.1	0.0	0.6	-0.4	0.1	0.4	-0.1	0.7
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.8	0.2	-1.8	-1.9	-1.1	-1.0	-0.4	1.9	-0.2	-0.5	1.6	-1.7	-0.1	0.5	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.3	-0.7	-1.1	0.3	-0.9	0.1	-0.3	1.0	-1.1	-0.7	0.6	-0.6	-0.0	0.5	-1.1
Mouth/teeth dental problems: Dentures	0.6	1.1	4.7	-0.8	0.2	0.5	0.5	-0.3	-0.4	0.3	-2.2	-1.0	-0.6	0.5	-1.3	-0.8	-2.1
Asthma	0.8	1.6	5.5	-0.8	-1.5	0.2	1.0	-2.4	-1.4	-0.2	-0.8	-1.2	-0.5	-1.3	-1.5	-2.0	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.8	-0.4	-0.4	0.1	0.7	-0.8	-0.9	-0.6	1.7	-0.1	-1.2	-0.8	-0.2	-0.7	1.1
Medication: Cholesterol lowering	0.3	0.5	1.4	0.9	0.6	0.1	0.2	0.2	0.8	-1.1	0.1	0.5	0.5	0.9	0.4	0.9	1.2
Depression (self-reported)	0.3	0.4	2.1	0.2	0.4	1.5	-0.1	0.7	0.5	0.4	1.1	0.4	-0.3	0.7	0.3	-0.2	0.2
Medication: Lansoprazole	0.5	0.6	2.1	0.5	1.5	0.8	0.5	0.4	0.9	-0.4	-1.0	0.4	-0.3	1.4	0.3	0.6	-0.0
Prospective memory result	0.5	0.6	1.8	0.3	1.1	-0.9	0.4	1.4	0.6	-0.5	0.8	0.6	0.2	1.2	0.0	0.5	-0.8
Lung cancer (father)	0.7	0.9	3.9	-0.8	-0.0	-0.8	0.4	-0.4	-0.8	-0.6	-1.6	-0.4	-2.0	-0.6	-0.6	-1.5	-0.3
Illnesses of mother	0.6	0.8	3.2	-1.0	1.8	-0.6	0.7	0.3	-0.4	-1.2	-0.3	-0.1	-1.2	0.8	-0.2	0.2	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	5.0	16.1	40.4	3.6	2.9	3.9	-3.5	6.4	4.9	2.6	4.2	4.7	2.5	3.0	5.5	4.1	1.6
Pulse wave Arterial Stiffness index	0.5	0.6	2.8	-0.3	1.7	-0.5	1.6	-0.5	-0.4	0.1	0.2	0.3	-0.7	0.5	-0.4	-0.5	-1.1
Impedance of arm (left)	1.3	6.2	12.1	-2.5	-2.9	-2.8	0.3	-3.5	-2.9	0.8	-2.5	-3.4	0.5	-2.7	-2.9	-1.7	-2.7
Arm fat mass (right)	1.9	7.8	18.7	2.4	2.9	4.3	-0.4	4.1	3.9	-0.5	1.6	2.6	1.0	4.2	2.8	1.7	2.4
Trunk predicted mass	6.1	34.6	68.6	6.3	5.7	6.1	-2.5	8.3	7.5	1.8	6.2	7.9	1.6	5.8	7.2	5.2	4.8
Standing height	4.5	44.6	84.5	7.3	6.5	5.2	-3.1	9.2	8.2	2.7	8.6	9.1	2.5	6.0	8.3	6.5	4.7
Length of working week for main job	2.7	3.0	5.1	2.2	-1.0	0.1	-2.0	1.9	1.9	2.1	1.7	1.9	2.2	0.0	2.2	1.2	1.3
Exposure to tobacco smoke at home	0.2	0.3	1.1	0.1	0.7	0.7	0.3	0.3	0.4	0.4	-0.0	0.0	-1.0	1.1	0.2	-0.2	-0.4
Breastfed as a baby	1.0	1.3	4.6	0.6	-0.3	1.9	-1.6	0.7	0.1	1.5	2.1	1.1	-0.3	-0.9	0.9	0.8	-0.8
Tense / ‘highly strung’	1.2	2.0	7.9	-0.2	0.9	0.0	2.8	-0.8	-0.3	-0.9	-0.0	-0.7	-2.1	1.7	-1.5	-2.4	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.5	-1.8	-0.2	-0.3	0.9	-1.2	-1.5	1.1	-0.2	-1.9	-1.3	-0.2	-1.6	-1.3	-1.4
Hair/balding pattern: Pattern 4	0.9	2.3	7.5	-1.2	1.1	-0.8	2.2	-0.7	-1.0	-2.6	-0.4	-1.0	-2.7	1.0	-1.6	-1.7	0.2
Birth weight of first child	1.3	2.4	6.5	1.5	0.8	2.6	-1.0	2.2	1.7	0.6	0.7	1.7	0.1	0.9	1.6	1.8	2.3
Peak expiratory flow (PEF)	5.1	11.8	25.5	2.9	2.8	2.1	-2.9	5.0	3.9	1.8	4.6	4.0	2.8	2.2	4.9	4.2	1.2
Pulse wave reflection index	0.2	0.2	0.9	-0.6	0.6	-0.3	0.6	-0.5	-0.5	-1.0	0.3	-0.3	-0.3	-0.1	-0.2	-0.1	-0.6
Ever highly irritable/argumentative for 2 days	0.3	0.4	3.0	-0.3	0.4	1.7	0.2	0.0	0.0	0.4	0.9	-0.2	-0.6	0.5	-0.3	-0.6	-0.6
Loud music exposure frequency	1.0	1.1	4.4	1.9	0.3	1.1	-0.1	0.1	0.9	-1.1	1.3	2.1	0.2	-0.2	0.8	0.1	1.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.9	0.3	0.2	-1.5	-0.0	0.0	0.2	-0.6	-0.4	0.2	0.9	-0.1	0.0	1.7	1.4
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.9	-0.7	0.6	0.1	1.7	-1.2	-0.8	-1.4	-0.2	-0.8	-1.7	1.0	-1.3	-1.4	-0.8
Blood clot in the leg (DVT)	0.3	0.3	1.3	1.1	-0.4	-0.3	0.1	-0.9	0.4	0.6	0.7	1.0	0.5	-0.4	0.0	-0.5	0.2
Medication: Paracetamol	0.6	1.0	5.5	0.6	-0.4	2.3	-0.9	1.4	1.3	0.5	-0.4	0.9	0.6	0.5	1.2	0.5	0.6
Headache pain in last month	0.1	0.1	0.3	0.5	-0.2	0.0	0.0	-0.2	-0.0	-0.5	0.6	0.6	-0.5	-0.6	0.2	-0.1	0.1
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	6.9	-1.0	-2.6	-0.5	-1.3	-0.9	-1.3	2.1	-0.1	-1.0	0.1	-2.6	-0.4	-0.9	-1.4
Glaucoma (self-reported)	0.9	1.0	3.8	0.7	1.4	1.5	0.9	0.7	1.0	-0.2	1.5	0.8	-0.3	2.0	0.4	-0.1	0.4
Gout (self-reported)	1.2	1.6	4.2	1.6	-0.0	2.0	-0.7	1.4	2.0	-0.8	0.7	1.2	1.1	1.1	1.2	0.8	1.6
Hypothyroidism/myxoedema (self-reported)	2.3	4.5	10.8	-2.7	0.2	-1.1	2.9	-1.8	-2.2	-1.6	-2.3	-2.9	-1.8	0.3	-3.3	-2.1	-1.8
Medication: Amlodipine	1.8	2.5	5.6	2.1	0.8	2.1	-0.4	1.5	2.0	-0.2	1.2	2.1	0.8	1.3	1.6	1.7	2.4
Medication: Ventolin 100micrograms inhaler	1.3	1.7	4.4	-0.5	-1.6	-0.4	0.5	-2.1	-1.2	0.2	-1.9	-1.0	0.1	-1.4	-1.6	-1.9	-1.4
Birth weight	5.0	10.8	22.1	3.9	1.8	3.6	-1.7	4.3	3.9	1.1	3.4	4.7	1.5	2.3	3.9	3.6	3.6
Chronic bronchitis/emphysema (mother)	1.8	2.1	5.1	2.3	-0.1	0.9	-1.2	0.9	1.9	2.0	1.1	1.8	1.2	0.3	2.0	0.8	1.9
High blood pressure (siblings)	0.4	0.6	2.2	-0.1	0.5	-1.5	-0.7	1.3	0.3	-0.3	1.0	0.6	0.3	0.3	0.6	1.5	-0.1
Forced vital capacity (FVC), Best measure	4.7	17.0	38.4	4.2	2.3	3.8	-3.7	6.2	5.1	2.9	4.8	5.2	2.9	2.5	5.6	3.8	2.0
Body fat percentage	0.8	3.0	12.1	0.8	2.0	2.9	1.2	2.0	2.0	-1.6	0.4	0.5	-0.3	3.5	0.7	-0.2	1.6
Leg fat percentage (right)	0.6	2.3	9.2	0.8	1.4	3.0	1.4	1.4	1.6	-1.8	-0.0	0.5	-0.8	2.7	0.4	-0.5	1.6
Arm fat-free mass (right)	6.7	34.1	67.4	6.2	6.1	6.3	-1.6	8.2	7.4	0.8	6.3	7.6	1.1	6.6	6.8	4.5	5.2
Exposure to tobacco smoke outside home	0.4	0.5	2.0	-0.5	0.8	-0.5	1.4	-0.5	-0.4	-0.6	-0.4	-0.4	-1.2	0.5	-0.8	-0.8	0.1
Comparative body size at age 10	0.2	0.6	2.2	0.3	-1.5	1.3	-1.4	0.9	0.2	-0.6	0.1	0.4	0.0	-0.9	0.7	-0.8	0.3
Number of full brothers	0.3	0.4	1.8	-0.6	-0.1	-0.0	0.2	-0.6	-0.9	0.3	-0.1	-0.1	-1.1	-0.7	-0.2	-0.7	-1.4
Worry too long after embarrassment	0.9	1.5	4.9	-0.0	-1.7	-1.8	0.8	-2.2	-1.3	-0.3	-1.4	-0.8	-0.3	-1.8	-1.0	-0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.5	0.2	1.3	0.1	0.5	0.1	0.2	0.4	-0.6	-0.7	0.9	-0.3	-0.1	0.9
Wheeze or whistling in the chest in last year	1.8	3.2	8.4	-1.4	-2.9	0.4	0.5	-2.7	-1.8	-0.3	-1.7	-2.2	-0.5	-2.1	-2.1	-2.5	-0.9
Number of children fathered	1.0	1.1	3.9	-0.2	-0.0	0.1	-2.0	1.6	0.3	0.7	1.8	0.5	-0.5	-0.3	1.6	1.6	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.8	-1.0	0.7	-0.8	0.9	-1.3	-1.1	0.1	-0.6	-0.9	-1.1	-0.2	-0.9	0.1	-1.0
Age at first live birth	1.5	2.6	7.1	-1.8	-2.0	-1.4	0.5	-2.7	-2.3	-0.1	-0.5	-2.2	-0.4	-1.8	-2.0	-1.3	-0.6
Pulse wave peak to peak time	0.8	0.9	3.0	0.7	-1.2	0.9	-1.7	1.1	1.0	0.1	0.2	0.2	0.9	-0.0	0.9	1.0	1.5
Health satisfaction	1.2	1.6	4.2	-1.7	-0.6	-0.9	1.1	-1.4	-1.5	-0.8	-0.1	-2.0	-1.2	-0.3	-1.9	-1.6	-0.4
Shortness of breath walking on level ground	0.5	0.6	2.8	0.2	-1.7	0.7	-0.7	-0.7	0.1	0.8	-1.1	-0.3	0.8	-1.0	-0.1	-0.5	-0.4
Qualifications: College or University degree	0.5	1.5	7.1	-0.4	-1.4	-2.7	0.0	-1.8	-1.1	1.0	1.3	-1.2	0.6	-1.1	-0.8	-0.6	0.2
Eye problems/disorders: None of the above	1.6	1.8	5.3	-1.1	-0.5	-2.3	0.6	-1.7	-1.6	-0.8	-1.6	-0.7	-1.3	-1.5	-0.9	-1.2	-1.6
Mouth/teeth dental problems: Loose teeth	1.8	2.2	4.6	-2.0	-0.6	-2.1	1.3	-1.1	-1.6	0.0	-0.3	-2.0	-1.0	-0.1	-2.1	-1.7	-1.7
Emphysema/chronic bronchitis	1.0	1.2	4.8	1.2	-0.4	2.2	-1.0	0.8	1.1	1.3	0.7	1.1	0.8	0.2	0.8	1.1	1.2
Medication for pain relief, constipation, heartburn	0.5	0.9	8.3	-0.4	-0.0	-2.9	0.5	-0.9	-0.6	-0.5	-0.7	-0.5	-0.0	-0.4	-0.7	-0.6	-0.7
Neck or shoulder pain in last month	0.4	0.5	2.7	-0.4	0.6	-0.0	1.0	-0.1	-0.3	-0.5	-0.3	-0.4	-1.6	1.0	-0.8	-0.7	-0.7
Medication: Blood pressure	1.5	2.7	8.3	1.3	2.9	0.6	0.9	1.3	1.8	-2.1	0.3	1.3	0.1	2.8	1.1	1.6	1.9
Angina (self-reported)	0.4	0.5	2.4	-0.8	-0.4	-1.1	-0.1	-0.1	-0.8	-0.5	-1.6	-0.9	-0.1	-0.6	-0.9	-0.0	-0.3
Migraine (self-reported)	0.1	0.2	1.3	-0.5	0.2	0.2	-0.0	0.6	-0.2	0.1	1.1	-0.4	-0.2	0.2	0.2	0.4	0.5
Medication: Ibuprofen	0.4	0.5	2.4	-0.5	-0.5	0.1	0.4	-0.6	-0.7	-0.3	1.6	-0.3	-1.1	-0.6	-0.2	-0.4	1.0
Medication: Allopurinol	1.3	1.7	5.0	1.3	0.1	2.2	-0.9	1.6	1.9	-0.6	0.8	1.0	1.0	1.1	1.2	0.9	1.9
Medication: Omeprazole	0.5	0.6	2.9	-0.2	1.2	1.4	0.8	0.4	0.5	0.1	-0.3	-0.1	-0.5	1.7	-0.2	-0.4	-0.8
Medication: Seretide 50 evohaler	1.2	1.4	2.7	0.9	-0.5	1.0	-1.6	1.0	1.0	0.5	0.9	1.0	1.6	-0.4	1.6	1.6	1.6
Mean time to correctly identify matches	0.3	0.5	1.3	-0.5	-0.8	0.9	0.7	-0.6	-0.1	0.2	-0.9	-1.1	-0.0	0.6	-1.0	-1.1	0.0
Heart disease (mother)	0.8	1.0	2.7	-0.6	0.1	-0.0	1.6	-0.9	-1.1	-1.5	0.1	-0.9	-1.6	0.3	-1.2	-1.1	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	3.9	8.2	-2.1	-1.5	-1.3	0.6	-2.6	-2.7	0.2	-2.9	-2.5	-1.6	-2.1	-2.1	-1.5	-1.8
Whole body fat mass	2.1	8.7	21.9	2.4	3.4	4.4	0.2	4.3	3.9	-0.8	2.3	2.6	0.4	4.7	2.7	1.6	2.7
Leg fat mass (right)	2.2	8.4	22.0	2.3	3.4	4.4	0.4	4.1	3.8	-1.3	2.2	2.5	0.1	4.7	2.5	1.5	2.8
Arm predicted mass (right)	6.5	33.4	66.7	6.2	6.0	6.3	-1.6	8.2	7.4	0.8	6.1	7.5	1.3	6.5	6.8	4.6	5.1
Pulse rate, automated reading	0.1	0.4	1.8	0.5	0.9	0.4	1.0	0.4	0.5	-0.0	-1.3	0.1	-0.1	1.4	-0.3	-0.2	0.1
Alcohol intake frequency.	2.6	6.0	13.8	2.1	2.2	3.3	-2.0	3.7	3.2	1.3	1.6	2.8	1.2	2.3	3.3	2.3	0.7
Comparative height size at age 10	2.0	11.3	24.9	3.7	3.8	2.9	-1.6	5.0	4.1	1.7	2.7	4.7	1.0	3.3	4.0	3.9	1.7
Number of full sisters	1.3	1.6	6.9	-0.5	-1.7	1.1	-2.6	0.7	-0.1	1.7	1.3	-0.2	0.8	-1.4	0.6	0.7	-1.4
Suffer from ‘nerves’	0.4	0.7	2.7	0.1	1.6	0.2	1.4	0.5	0.4	0.4	0.4	0.2	-0.9	1.6	-0.1	-0.6	0.2
Overall health rating	0.1	0.3	0.7	-0.4	-0.6	0.9	-0.4	0.2	0.1	0.8	-0.8	-0.8	0.2	0.3	-0.4	-0.1	-0.4
Chest pain or discomfort	0.9	1.2	3.8	-1.0	-0.9	-0.4	1.2	-1.4	-0.9	-0.5	-0.0	-1.8	-0.5	0.1	-1.8	-2.0	0.6
Had major operations	2.3	2.7	6.2	1.3	-0.2	1.3	-2.5	1.8	1.6	1.5	1.6	1.7	2.1	-0.1	2.1	2.4	-0.2
Age at last live birth	1.1	1.6	5.6	-0.7	-1.4	-1.6	0.7	-2.4	-1.4	0.4	-0.4	-1.4	0.1	-1.1	-1.6	-1.1	-1.1
Family relationship satisfaction	2.7	3.3	10.1	-2.0	-0.9	-1.1	1.5	-3.2	-2.5	-0.6	0.0	-2.3	-1.6	-1.5	-2.3	-2.0	-1.1
Leg pain on walking	0.8	1.0	2.9	-1.4	-1.2	0.9	-0.4	-0.5	-1.0	0.8	-0.5	-1.4	-0.2	-0.9	-0.7	-1.3	-1.7
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.4	0.6	0.6	0.2	-0.2	1.2	0.7	-1.1	-1.1	0.7	0.5	0.6	0.4	1.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	-0.1	0.7	-0.1	0.7	0.9	0.2	-0.9	-0.2	-0.1	-0.7	1.2	-0.1	-0.5	0.8
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.2	1.2	1.5	-0.2	1.3	0.3	0.6	-1.1	1.1	1.2	-0.6	1.1	0.5	0.3	1.3
Medication: Aspirin	0.7	0.9	6.7	0.0	1.1	2.6	0.6	0.3	0.3	-0.6	0.5	-0.1	-0.3	1.1	-0.3	0.7	1.0
Supplements: Vitamin C	1.1	1.3	5.1	0.3	2.2	0.8	1.0	1.0	0.5	-0.2	2.2	0.6	-1.3	1.7	0.6	-0.4	-0.7
Knee pain experienced in last month	0.6	0.9	3.8	-0.6	1.4	1.9	-0.1	0.6	0.2	0.6	-0.4	-0.4	-0.9	1.0	0.5	0.8	-1.6
Hypertension (Self-reported)	2.3	6.5	21.9	1.9	4.6	1.9	1.5	2.7	3.0	-2.2	0.7	2.2	-0.6	4.7	1.4	1.9	2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.1	0.8	0.3	0.7	-0.0	0.1	0.6	0.5	-0.1	0.4	-0.0	0.5	0.3	-0.1	-1.1
Illnesses of father: Heart disease	0.7	1.0	2.5	-0.7	-0.4	-1.4	1.2	-1.2	-1.1	-1.6	-0.2	-1.3	0.5	-0.2	-1.5	-0.4	0.1
Illnesses of siblings: Diabetes	2.0	2.5	7.1	1.3	0.7	1.5	-1.3	2.0	1.7	2.7	1.3	1.3	1.7	1.2	1.5	2.2	0.1
Smoking status: Previous	0.8	1.2	3.5	-0.6	0.3	-1.2	1.3	-1.9	-1.2	-1.5	-0.9	-0.6	-1.5	-0.5	-1.0	-1.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	4.0	8.2	18.1	3.3	2.4	2.5	-0.6	3.1	3.3	0.9	4.3	3.6	1.0	2.6	3.3	2.7	3.6
Whole body fat-free mass	6.2	35.2	72.6	6.2	6.1	6.1	-2.3	8.5	7.6	1.3	6.2	7.7	1.7	6.3	7.2	5.3	4.8
Leg fat-free mass (right)	6.1	32.8	71.1	5.7	6.2	5.7	-2.3	8.4	7.3	1.1	5.8	7.2	1.9	6.4	6.8	5.5	4.4
Arm fat percentage (left)	0.5	2.2	8.8	0.9	1.1	3.0	0.5	1.7	2.1	-1.0	-0.1	0.4	0.5	2.8	0.8	-0.0	1.5
Average weekly red wine intake	0.1	0.2	2.0	-0.2	0.1	-1.4	0.2	-0.5	-0.3	-0.1	-0.0	-0.1	0.1	-0.1	-0.6	-0.0	-0.5
Handedness (chirality/laterality): Left-handed	1.4	1.6	4.3	1.8	0.4	0.6	-1.3	1.5	1.5	0.6	-0.2	2.0	0.9	-0.0	2.1	1.6	0.8
Mood swings	1.1	2.0	4.8	-2.2	-1.4	-0.5	0.0	-1.7	-2.0	0.7	-0.5	-2.1	-0.9	-1.8	-1.8	-1.0	-1.1
Loneliness, isolation	0.8	1.1	3.2	-0.2	1.6	0.5	1.8	-0.2	0.1	-0.6	1.1	-0.2	-1.6	1.7	-1.0	-1.1	-0.0
Long-standing illness, disability or infirmity	0.3	0.4	1.9	-0.4	-0.3	1.4	0.4	-0.7	-0.3	0.2	-0.7	-0.7	-0.8	0.2	-0.9	-0.8	-0.2
Ever had bowel cancer screening	2.3	2.7	6.4	-2.0	-0.6	0.4	1.4	-1.9	-1.9	-1.5	-0.4	-2.1	-2.4	-0.6	-2.5	-2.1	-1.0
Diabetes diagnosed by doctor	1.1	1.8	4.8	1.1	0.8	2.1	-0.9	1.0	1.7	2.2	1.1	0.7	1.4	1.6	0.8	1.4	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	4.2	-0.2	-0.2	-2.1	0.6	-1.3	-0.7	-0.5	0.0	-0.4	0.0	-1.0	-0.3	-1.0	-0.7
Friendships satisfaction	3.1	3.8	7.8	-2.3	-2.5	-1.5	0.3	-2.8	-2.8	0.6	1.3	-2.7	-1.1	-2.3	-1.9	-1.8	-1.1
Qualifications: nursing, teaching	0.4	0.6	2.1	-0.4	-1.2	-1.5	-0.5	-0.8	-0.4	0.7	0.7	-1.3	0.6	-0.5	-0.5	-0.6	0.0
Commuting to job workplace: Walk	0.5	0.6	2.4	0.2	-1.0	-0.3	-1.0	-0.3	-0.4	0.9	-0.2	0.4	1.3	-1.5	0.3	0.7	-0.4
Eye problems/disorders: Cataract	0.2	0.2	0.8	-0.1	-0.1	0.5	0.2	0.2	-0.1	-0.9	0.8	-0.2	0.0	0.2	-0.6	0.1	0.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	4.4	0.6	1.7	1.3	0.8	1.3	1.3	-1.3	0.9	0.5	-0.3	2.1	0.7	-0.2	0.9
Medication for cholesterol	1.0	1.5	5.7	-0.7	-1.1	-2.4	-1.4	-0.4	-0.6	1.7	-0.5	-0.7	1.0	-1.5	0.5	0.5	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.6	4.2	-1.3	-1.1	0.5	0.7	-2.0	-1.4	-0.3	-2.0	-1.6	-0.8	-1.2	-1.4	-1.1	-0.2
Back pain experienced in last month	1.6	2.3	4.3	-1.6	-1.1	-0.7	0.6	-1.9	-2.0	-0.8	-1.7	-1.9	-2.1	-1.4	-1.9	-1.6	-0.3
Mineral and other dietary supplements	2.6	3.5	9.1	1.6	-0.4	1.1	-2.4	1.9	2.2	2.1	1.5	1.1	3.0	0.5	1.8	2.3	2.1
Breast cancer (self-reported)	0.3	0.4	1.5	0.2	-0.6	1.0	-0.9	0.4	0.3	0.7	-1.2	0.1	-0.1	-0.4	0.4	0.3	0.5
Asthma (self-reported)	0.7	1.3	4.5	-0.7	-1.5	0.4	0.7	-2.1	-1.3	-0.0	-0.7	-1.0	-0.4	-1.4	-1.2	-1.6	-0.8
Osteoporosis (self-reported)	0.5	0.6	3.1	0.9	0.7	-0.6	0.8	0.2	0.8	-0.9	-1.8	0.6	0.3	1.0	0.0	-0.2	-0.2
Osteoarthritis (self-reported)	0.9	1.2	5.3	-1.2	0.8	0.8	1.2	-0.1	-0.6	0.2	-0.2	-1.3	-2.3	1.3	-1.1	-1.3	-0.9
Medication: Aspirin	1.0	1.4	8.5	-0.1	1.6	2.9	0.9	0.6	0.5	-0.9	0.6	-0.2	-0.4	1.8	-0.3	0.7	1.2
Medication: Gliclazide	1.4	1.6	3.5	1.4	-0.1	0.9	-1.9	1.2	1.6	1.8	-0.3	1.3	1.2	0.0	1.5	1.4	0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	1.1	0.1	0.5	0.8	0.0	0.1	0.2	0.2	0.8	0.6	-1.0	0.0	0.6	-0.3	0.2
Smoking status: Current	0.4	0.6	2.7	0.1	-1.4	0.1	-0.8	-0.1	0.1	1.6	-0.4	-0.3	1.4	-0.9	0.2	-0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	3.9	11.7	0.9	1.0	2.8	-1.9	3.4	2.1	1.8	2.1	1.3	2.0	1.5	2.4	2.1	0.1
Whole body water mass	6.3	35.9	72.9	6.3	6.0	6.2	-2.4	8.5	7.6	1.4	6.3	7.8	1.9	6.2	7.2	5.4	4.9
Leg predicted mass (right)	6.0	32.0	69.8	5.6	6.0	5.6	-2.3	8.4	7.2	1.1	5.7	7.1	1.9	6.3	6.7	5.4	4.4
Arm fat mass (left)	2.1	8.5	20.2	2.7	2.9	4.5	-0.4	4.2	4.1	-0.5	1.9	2.8	0.9	4.2	3.0	1.7	2.7
Number of self-reported non-cancer illnesses	1.7	2.9	9.3	0.0	2.2	1.6	3.0	-0.6	0.1	-1.9	-0.0	-0.1	-2.9	2.5	-1.4	-1.5	0.8
Average weekly champagne plus white wine intake	0.6	0.9	2.5	-1.6	0.7	-0.5	0.5	-0.7	-1.4	0.2	-0.3	-1.6	-1.5	0.1	-0.7	-0.1	-1.1
Miserableness	0.4	0.8	1.7	-0.9	-0.4	0.1	0.8	-1.3	-1.2	0.1	-0.7	-0.8	-1.3	-0.7	-1.1	-1.0	-0.8
Guilty feelings	3.4	5.1	9.7	-2.4	0.2	-2.8	2.9	-3.1	-2.8	-1.7	-1.1	-2.3	-2.4	-0.7	-3.1	-2.5	-0.8
Wears glasses or contact lenses	0.6	0.7	2.6	-1.2	-0.5	-0.5	-0.7	-0.0	-1.1	-0.1	-0.8	-0.6	-0.8	-1.2	-0.5	0.2	-1.6
Ever taken oral contraceptive pill	1.9	2.2	4.6	-1.6	-1.6	-1.3	1.1	-2.1	-1.9	-1.6	-1.0	-1.7	-0.2	-1.6	-1.9	-1.3	0.2
Hearing aid user	1.9	2.2	5.4	-1.2	0.8	-1.1	2.2	-1.8	-1.5	-2.3	-0.4	-1.0	-1.8	0.0	-1.9	-1.4	-1.1
Mother’s age at death	0.7	0.9	3.8	-0.8	-0.1	-1.9	1.1	-0.9	-1.1	-0.3	-0.6	-1.1	-0.9	-0.1	-1.0	-1.1	0.0
Financial situation satisfaction	0.2	0.3	1.2	-0.7	0.1	-0.0	0.2	0.0	-0.2	0.3	1.1	-0.6	-0.3	0.5	-0.5	-0.5	-0.9
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.7	0.0	-0.9	-1.2	-0.2	-0.7	-0.6	1.3	0.2	-0.2	0.0	-0.9	-0.5	0.5	-0.4
Commuting to job workplace: Public transport	0.4	0.4	2.3	-0.0	-1.3	0.5	-0.4	-0.4	-0.4	0.7	1.5	-0.3	0.1	-0.7	-0.1	-0.1	-0.5
Eye problems/disorders: Glaucoma	0.3	0.3	1.7	0.3	0.3	1.3	0.3	0.3	0.6	0.1	0.9	0.1	0.4	1.0	0.0	0.1	0.3
Medication: Blood pressure	1.7	3.2	10.2	1.7	2.4	2.3	0.8	2.2	2.3	-1.1	0.3	1.7	-0.2	3.2	0.8	0.7	2.3
Pain type(s) experienced in last month: Hip pain	1.4	1.8	7.6	-1.1	-1.7	0.1	0.4	-1.5	-1.3	0.6	-2.8	-2.0	-0.6	-1.0	-1.4	-1.2	-0.7
Supplements: Fish oil (including cod liver oil)	2.1	2.7	7.4	-1.2	1.4	-1.6	2.7	-1.1	-1.5	-2.3	-0.9	-0.7	-2.4	0.6	-1.5	-1.9	-1.5
High cholesterol (Self-reported)	1.6	2.8	12.2	1.0	1.9	0.7	2.5	-0.2	0.7	-3.5	0.2	0.9	-1.5	1.8	-0.3	-0.2	2.8
Medication: Bendroflumethiazide	2.4	3.7	7.0	2.3	1.8	2.1	-0.4	2.5	2.6	-0.5	1.2	2.5	0.8	2.4	1.8	1.9	2.2
Medication: Paracetamol	1.0	1.6	4.4	0.9	-0.9	2.1	-1.6	1.7	1.7	0.9	-0.4	0.9	1.3	0.4	1.6	0.9	0.8
Medication: Lisinopril	0.2	0.2	0.7	0.6	-0.4	-0.7	0.5	-0.8	-0.1	-0.5	-0.8	-0.0	-0.1	-0.2	-0.3	-0.3	0.5
Medication: Atorvastatin	2.4	2.9	7.4	2.4	0.2	2.7	-1.1	1.6	2.6	1.4	0.6	1.8	1.6	1.5	1.7	1.1	1.8
Illnesses of father: High blood pressure	0.9	1.1	8.8	-0.3	0.2	-0.8	1.0	-0.5	-0.4	-3.0	-1.2	-0.1	-1.1	0.1	-0.7	-1.0	-0.3
Alcohol drinker status: Never	0.9	1.1	2.8	-1.4	1.4	0.9	0.2	1.1	-0.1	1.1	-0.6	-1.2	-0.5	1.7	-0.4	-0.4	-1.6
Ever smoked	0.2	0.4	0.9	-0.3	0.3	-0.5	1.0	-0.9	-0.7	-0.8	0.7	-0.3	-0.7	-0.2	-0.5	-0.8	0.6
Basal metabolic rate	6.0	33.3	68.4	6.0	6.0	6.2	-2.0	8.3	7.4	1.0	5.9	7.4	1.6	6.4	6.9	5.0	4.8
Leg fat percentage (left)	0.6	2.3	8.0	0.9	1.5	2.8	1.3	1.5	1.6	-1.7	0.0	0.5	-0.9	2.8	0.5	-0.5	1.6
Arm fat-free mass (left)	5.9	30.0	61.6	5.6	5.8	6.1	-1.6	7.8	6.9	0.9	5.9	7.0	1.0	6.1	6.5	4.4	4.7
Number of operations (self-reported)	0.3	0.4	1.7	-0.2	-0.5	-0.6	0.4	-0.4	-0.6	0.3	-0.4	-0.3	-0.8	-0.6	-0.9	-1.3	-0.3
Average weekly beer plus cider intake	0.6	0.8	2.6	0.7	0.4	0.2	-0.5	1.2	1.2	-0.9	1.0	0.8	1.6	0.8	1.0	0.7	0.4
Irritability	2.3	3.9	8.4	-2.6	0.5	-1.0	2.9	-2.1	-2.3	-0.5	-0.1	-2.7	-2.4	0.6	-2.5	-2.7	-0.8
Risk taking	0.7	1.1	3.0	0.8	0.2	1.5	-0.9	1.3	1.3	0.9	1.7	0.4	-0.1	1.5	0.9	0.6	0.8
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.1	1.4	0.1	1.1	-0.5	0.3	0.9	-0.1	0.6	1.2	0.1	0.0	0.8	0.3	1.3
Fractured/broken bones in last 5 years	1.5	1.9	6.1	-1.0	-1.9	0.3	-0.7	-1.3	-1.3	1.7	-2.5	-1.4	0.4	-1.9	-1.1	-0.4	-1.4
Age started oral contraceptive pill	0.1	0.1	0.3	0.1	-0.5	0.0	0.0	-0.5	-0.3	0.1	-0.1	-0.1	0.4	-0.6	-0.2	-0.0	0.6
Diastolic blood pressure, automated reading	1.6	4.8	16.4	1.9	4.0	0.9	2.1	2.7	2.4	-2.3	-0.7	2.1	-1.0	4.0	1.0	0.4	1.3
Ever depressed for a whole week	0.5	0.6	1.8	-0.9	-0.1	0.3	0.9	-1.0	-1.0	-1.0	-0.1	-0.8	-1.4	-0.1	-0.9	-0.6	-0.6
Unable to work because of sickness or disability	0.6	0.7	1.7	-1.0	-1.3	-0.8	-0.5	-0.6	-0.8	0.9	-0.8	-1.3	0.3	-1.0	-0.6	-0.8	-0.7
Commuting to job workplace: Cycle	1.3	1.6	3.5	-1.7	-1.0	-0.3	0.3	-1.5	-1.8	0.2	-0.6	-1.4	-0.9	-1.9	-1.1	-1.4	-1.9
Myopia	0.9	1.3	2.7	1.6	1.0	1.5	-0.7	1.4	1.6	0.3	-0.6	1.2	0.8	1.4	1.1	1.4	0.2
Vascular/heart problems diagnosed by doctor	1.6	4.3	15.5	-1.8	-3.7	-1.6	-1.5	-2.0	-2.5	1.7	0.3	-1.7	0.4	-3.9	-0.9	-1.6	-1.9
Cholesterol lowering medication	2.1	3.0	8.1	0.9	2.3	2.5	2.3	0.7	1.1	-2.2	0.6	0.6	-1.3	2.9	-0.3	-0.2	2.7
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.6	-0.4	1.2	1.3	0.7	0.6	0.4	0.5	-0.6	-0.3	0.1	1.6	-0.4	-0.1	-1.2
Pain experienced in last month	0.2	0.3	2.0	0.0	-0.1	0.1	-0.5	0.5	0.5	0.7	0.4	0.0	1.4	0.3	0.3	0.4	0.5
Supplements: Calcium	0.3	0.3	1.6	-0.1	-0.4	0.1	-0.7	-0.5	-0.4	-0.4	0.6	-0.2	-0.7	-0.8	0.4	0.3	-1.3
Basal cell carcinoma (self-reported)	0.9	1.0	2.2	1.2	0.8	0.3	-0.7	1.5	1.4	1.3	0.5	1.3	0.9	0.9	1.0	1.1	0.3
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.1	-0.9	-0.1	0.3	0.9	-1.3	-1.1	-0.5	-2.3	-1.1	-1.1	-0.3	-1.0	-0.6	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.6	1.2	-0.0	-0.5	0.4	-0.7	0.4	0.2	0.8	1.2	0.4	-0.3	0.1	-0.4	0.3
Heart disease (siblings)	2.7	3.3	9.0	-2.3	1.7	0.8	2.6	-0.9	-1.7	-1.9	0.2	-1.9	-3.0	1.2	-2.1	-2.1	-0.8
Alcohol drinker status: Previous	0.2	0.2	0.8	0.6	0.5	-0.0	0.1	-0.3	0.1	-0.4	0.8	0.9	-0.7	-0.2	0.5	-0.3	0.1
Pack years of smoking	0.6	0.9	4.2	0.4	0.0	1.8	-0.7	0.8	1.0	0.2	-2.0	0.2	1.3	0.4	0.2	0.7	-0.3
Impedance of whole body	1.7	8.9	18.6	-2.9	-3.1	-3.6	1.5	-4.3	-3.6	-0.1	-2.6	-4.0	-0.6	-2.9	-3.7	-2.8	-2.5
Leg fat mass (left)	2.3	9.0	22.7	2.6	3.4	4.4	0.3	4.2	3.9	-1.2	2.2	2.7	0.2	4.8	2.7	1.6	2.9
Arm predicted mass (left)	5.6	28.3	59.6	5.3	5.8	6.0	-1.4	7.7	6.6	0.6	5.7	6.7	0.7	6.1	6.2	4.2	4.7