Best TWAS P=1.51e-14 · Best GWAS P=9.75e-16 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -7.7 | 7.7 | 1.5e-14 | -0.98 | 0.02 | 0.95 | TRUE |
2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -4.3 | 6.0 | 2.6e-09 | -0.74 | 0.10 | 0.89 | FALSE |
3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 0.00262 | -3.6 | -5.3 | 1.1e-07 | 0.41 | 0.34 | 0.06 | FALSE |