Best TWAS P=1.6e-08 · Best GWAS P=2.13e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | NUDT18 | 0.10 | 0.07 | enet | 10 | 0.07 | 2.3e-06 | 5.6 | 5.3 | 1.1e-07 | 0.91 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | NUDT18 | 0.10 | 0.04 | enet | 6 | 0.03 | 4.7e-03 | 5.1 | 5.4 | 5.3e-08 | 0.94 | 0.01 | 0.93 | FALSE |
| 3 | GTEx | Esophagus Mucosa | AC091171.1 | 0.14 | 0.07 | lasso | 4 | 0.05 | 2.2e-04 | 5.6 | 5.7 | 1.6e-08 | 0.98 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | FAM160B2 | 0.06 | 0.07 | lasso | 1 | 0.06 | 2.3e-04 | 5.5 | 5.5 | 4.5e-08 | 0.95 | 0.01 | 0.94 | FALSE |
| 5 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NUDT18 | 0.15 | 0.17 | lasso | 4 | 0.12 | 2.3e-04 | -4.8 | -5.2 | 2.4e-07 | -0.81 | 0.02 | 0.94 | FALSE |