[Hub]/) : Traits : Hip circumference :

chr8:8,092,025-12,973,575

Best TWAS P=2.59e-09 · Best GWAS P=2.52e-09 conditioned to 1.88e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM86B1 0.02 0.02 lasso 3 0.01 1.3e-02 4.9 5.5 4.0e-08 0.35 0.02 0.94 FALSE
2 CommonMind Brain Pre-frontal Cortex FAM90A25P 0.11 0.08 lasso 3 0.08 1.4e-09 5.0 5.3 9.0e-08 0.27 0.00 1.00 FALSE
3 GTEx Adipose Visceral Omentum AF131215.9 0.18 0.16 lasso 7 0.16 2.0e-08 4.8 5.2 1.9e-07 0.41 0.50 0.50 FALSE
4 GTEx Adrenal Gland FAM86B3P 0.16 0.00 enet 18 0.03 2.2e-02 4.3 -5.2 2.5e-07 -0.18 0.04 0.09 FALSE
5 GTEx Adrenal Gland AF131215.2 0.20 0.16 enet 12 0.13 2.2e-05 4.9 5.3 1.4e-07 0.41 0.46 0.53 FALSE
6 GTEx Adrenal Gland AF131215.9 0.18 0.16 lasso 10 0.18 3.5e-07 4.9 5.3 1.1e-07 0.41 0.47 0.51 FALSE
7 GTEx Artery Aorta AF131215.2 0.09 0.09 lasso 7 0.08 2.0e-05 -5.0 5.4 6.2e-08 0.44 0.46 0.50 FALSE
8 GTEx Artery Aorta AF131215.9 0.13 0.05 lasso 6 0.07 1.3e-04 5.1 5.4 7.8e-08 0.41 0.39 0.59 FALSE
9 GTEx Breast Mammary Tissue AF131215.2 0.16 0.15 lasso 6 0.12 1.1e-06 -5.0 5.1 2.9e-07 0.45 0.47 0.50 FALSE
10 GTEx Breast Mammary Tissue (Female) AF131215.9 0.04 -0.01 enet 6 0.02 7.3e-02 -4.5 5.2 2.2e-07 0.39 0.08 0.17 FALSE
11 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 4.9 -5.4 8.0e-08 -0.29 0.03 0.97 FALSE
12 GTEx Esophagus Mucosa AF131215.9 0.18 0.16 lasso 14 0.19 1.6e-12 4.4 5.2 1.6e-07 0.44 0.49 0.50 FALSE
13 GTEx Esophagus Muscularis AF131215.9 0.14 0.17 enet 16 0.17 1.6e-10 -4.6 5.4 7.7e-08 0.42 0.76 0.23 FALSE
14 GTEx Heart Left Ventricle AF131215.2 0.05 0.01 enet 11 0.01 1.5e-01 4.7 5.4 7.7e-08 0.41 0.32 0.31 FALSE
15 GTEx Heart Left Ventricle AF131215.9 0.07 0.10 enet 8 0.10 9.4e-06 -4.6 5.1 2.7e-07 0.40 0.61 0.31 FALSE
16 GTEx Nerve Tibial AF131215.2 0.19 0.18 lasso 12 0.23 3.5e-16 -4.6 5.2 1.7e-07 0.43 0.62 0.38 FALSE
17 GTEx Pancreas AF131215.2 0.16 0.16 enet 17 0.15 9.1e-07 -4.6 5.2 2.3e-07 0.42 0.55 0.44 FALSE
18 GTEx Pancreas AF131215.9 0.25 0.24 enet 14 0.22 1.0e-09 5.1 5.3 9.5e-08 0.41 0.36 0.64 FALSE
19 GTEx Skin Sun Exposed Lower leg FAM85A 0.09 0.04 enet 28 0.04 1.4e-04 -4.8 5.3 1.2e-07 0.17 0.03 0.94 FALSE
20 GTEx Skin Sun Exposed Lower leg AF131215.9 0.19 0.17 enet 29 0.21 3.9e-17 -4.6 5.6 2.6e-08 0.40 0.81 0.19 FALSE
21 GTEx Testis AF131215.2 0.28 0.18 enet 41 0.17 8.0e-08 -4.5 5.3 1.4e-07 0.54 0.74 0.25 FALSE
22 GTEx Thyroid AF131215.2 0.11 0.15 enet 17 0.18 1.2e-13 -4.5 5.3 1.2e-07 0.42 0.82 0.18 FALSE
23 NTR Blood MSRA 0.02 0.01 blup 833 0.01 2.3e-05 3.6 -5.9 3.9e-09 -0.34 0.44 0.55 FALSE
24 NTR Blood PPP1R3B 0.03 0.02 enet 11 0.02 1.5e-07 4.5 5.4 7.6e-08 0.28 0.13 0.85 FALSE
25 ROSMAP Brain Pre-frontal Cortex XKR6 0.11 0.10 enet 23 0.13 1.2e-16 -4.1 5.5 4.3e-08 0.44 0.83 0.17 FALSE
26 ROSMAP Brain Pre-frontal Cortex AF131215.3 0.08 0.10 lasso 7 0.12 8.3e-16 5.0 5.2 2.1e-07 0.39 0.44 0.55 FALSE
27 ROSMAP Brain Pre-frontal Cortex RP11-481A20.11 0.06 0.04 blup 286 0.04 2.2e-06 5.0 6.0 2.6e-09 0.32 0.04 0.96 TRUE