Best TWAS P=1.19e-16 · Best GWAS P=1.21e-18 conditioned to 0.0153
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NEBL | 0.07 | 0.01 | blup | 662 | 0.03 | 9.7e-05 | -4.8 | -6.0 | 2.2e-09 | -0.03 | 0.76 | 0.01 | TRUE |
| 2 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 1.3e-02 | 4.5 | 6.4 | 1.8e-10 | 0.52 | 0.27 | 0.44 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.0e-04 | 8.2 | -8.3 | 1.2e-16 | -0.94 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 6.1e-02 | 6.6 | 7.4 | 9.8e-14 | 0.90 | 0.09 | 0.81 | FALSE |
| 5 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 1.0e-01 | 6.6 | -7.4 | 1.0e-13 | -0.92 | 0.02 | 0.64 | FALSE |