[Hub]/) : Traits : Standing height :

chr7:55,291,079-56,840,887

Best TWAS P=1.06e-12 · Best GWAS P=6.17e-10 conditioned to 0.206

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia GBAS 0.19 0.11 lasso 5 0.07 4.1e-03 5.5 -6.0 2.2e-09 -0.91 0.03 0.71 FALSE
2 GTEx Brain Cerebellum GBAS 0.24 0.01 lasso 10 0.03 4.6e-02 -4.6 -5.5 3.5e-08 -0.54 0.05 0.50 FALSE
3 GTEx Brain Hypothalamus GBAS 0.21 0.12 lasso 3 0.08 6.3e-03 6.0 -6.1 8.8e-10 -0.89 0.02 0.76 FALSE
4 GTEx Cells Transformed fibroblasts GBAS 0.16 0.01 enet 26 0.07 9.2e-06 -1.5 -5.9 4.4e-09 -0.48 0.13 0.79 FALSE
5 GTEx Esophagus Mucosa CCT6A 0.06 0.03 lasso 2 0.02 1.1e-02 -5.2 -5.2 2.3e-07 -0.31 0.15 0.19 FALSE
6 GTEx Lung GBAS 0.07 0.00 lasso 3 0.00 1.9e-01 6.0 -6.5 1.0e-10 -0.88 0.02 0.84 FALSE
7 GTEx Nerve Tibial GBAS 0.14 0.01 lasso 3 0.04 1.0e-03 6.0 -5.2 2.7e-07 -0.78 0.01 0.96 FALSE
8 GTEx Pancreas GBAS 0.19 0.05 enet 35 0.07 6.6e-04 -3.6 -5.2 1.7e-07 -0.50 0.06 0.86 FALSE
9 GTEx Prostate GBAS 0.33 0.08 lasso 8 0.13 3.4e-04 -5.2 -5.8 4.9e-09 -0.41 0.14 0.29 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic GBAS 0.08 0.00 lasso 9 0.01 6.3e-02 6.0 -6.9 5.0e-12 -0.69 0.04 0.67 FALSE
11 GTEx Skin Sun Exposed Lower leg CHCHD2 0.07 0.09 lasso 5 0.05 3.6e-05 5.7 5.6 2.4e-08 0.96 0.02 0.98 FALSE
12 GTEx Skin Sun Exposed Lower leg GBAS 0.14 0.09 enet 32 0.10 1.3e-08 6.0 -5.4 6.7e-08 -0.71 0.02 0.98 FALSE
13 GTEx Stomach GBAS 0.19 0.01 enet 26 0.07 3.7e-04 -5.2 -5.3 8.7e-08 -0.44 0.12 0.57 FALSE
14 GTEx Testis GBAS 0.17 0.03 enet 28 0.09 8.2e-05 6.0 -5.4 6.2e-08 -0.60 0.06 0.84 FALSE
15 GTEx Testis ZNF713 0.15 0.00 enet 10 0.00 1.9e-01 -5.6 5.5 3.7e-08 0.64 0.02 0.51 FALSE
16 GTEx Thyroid GBAS 0.31 0.14 lasso 9 0.30 1.3e-23 -1.5 -5.3 1.3e-07 -0.46 0.10 0.90 FALSE
17 METSIM Adipose CCT6A 0.03 0.04 lasso 1 0.03 2.0e-05 -6.2 -6.2 7.6e-10 -0.44 0.00 1.00 FALSE
18 METSIM Adipose CHCHD2 0.30 0.27 bslmm 256 0.27 4.1e-41 5.9 5.6 2.7e-08 0.96 0.03 0.97 FALSE
19 ROSMAP Brain Pre-frontal Cortex GBAS 0.17 0.06 lasso 5 0.11 2.7e-14 -6.2 -7.1 1.1e-12 -0.75 0.00 1.00 TRUE
20 YFS Blood CCT6A 0.03 0.02 lasso 4 0.02 5.5e-06 -6.2 -5.8 9.0e-09 -0.39 0.00 1.00 FALSE
21 YFS Blood GBAS 0.02 0.01 lasso 6 0.01 2.0e-03 -6.2 -5.9 4.7e-09 -0.39 0.00 0.98 FALSE
22 The Cancer Genome Atlas Bladder Urothelial Carcinoma CHCHD2 0.06 0.06 lasso 4 0.06 1.8e-05 5.9 5.9 2.9e-09 0.95 0.01 0.99 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma GBAS 0.05 0.03 blup 48 0.04 2.8e-08 -5.2 -5.7 9.7e-09 -0.44 0.14 0.84 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma PSPH 0.03 0.00 enet 6 0.02 3.8e-05 1.6 -5.8 5.2e-09 -0.30 0.07 0.27 FALSE
25 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CHCHD2 0.07 0.04 enet 8 0.06 4.2e-04 5.7 5.1 3.1e-07 0.85 0.01 0.88 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma GBAS 0.18 0.06 enet 12 0.13 6.0e-15 -2.0 -5.6 1.8e-08 -0.47 0.93 0.06 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma PHKG1 0.04 0.02 blup 36 0.03 2.7e-04 5.7 6.2 6.2e-10 0.91 0.01 0.94 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma SUMF2 0.04 0.04 enet 5 0.04 1.4e-05 5.7 5.7 1.6e-08 0.47 0.04 0.95 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma CHCHD2 0.03 0.02 lasso 2 0.02 1.2e-03 5.9 5.5 3.7e-08 0.91 0.01 0.98 FALSE
30 The Cancer Genome Atlas Pancreatic Adenocarcinoma GBAS 0.18 0.00 blup 48 0.11 2.6e-05 -2.0 -5.2 2.0e-07 -0.37 0.02 0.27 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma GBAS 0.20 0.08 blup 48 0.21 8.4e-22 -5.2 -5.5 3.2e-08 -0.36 0.16 0.84 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma GBAS 0.25 0.08 enet 22 0.26 5.5e-25 -1.5 -5.8 5.8e-09 -0.45 0.75 0.24 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma PHKG1 0.07 0.06 enet 4 0.06 3.9e-06 -5.1 -6.2 6.2e-10 -0.54 0.04 0.96 FALSE