Best TWAS P=1.87e-07 · Best GWAS P=5.64e-07 conditioned to 0.32
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RSBN1L-AS1 | 0.16 | 0.12 | lasso | 8 | 0.16 | 1.5e-07 | -4.4 | -5.2 | 1.9e-07 | -0.86 | 0.04 | 0.93 | TRUE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | TMEM60 | 0.08 | 0.06 | blup | 29 | 0.05 | 2.1e-03 | 4.8 | -5.2 | 1.9e-07 | -0.72 | 0.00 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TMEM60 | 0.05 | 0.02 | blup | 29 | 0.03 | 7.9e-03 | 4.8 | -5.2 | 2.7e-07 | -0.73 | 0.01 | 0.45 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TMEM60 | 0.02 | 0.03 | blup | 29 | 0.02 | 6.8e-03 | 4.8 | -5.2 | 2.2e-07 | -0.72 | 0.01 | 0.69 | FALSE |