Best TWAS P=4.35e-15 · Best GWAS P=2.79e-10 conditioned to 9.91e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DNAJC30 | 0.13 | 0.07 | enet | 32 | 0.07 | 2.7e-09 | 5.5 | 7.6 | 2.2e-14 | -0.18 | 0.14 | 0.86 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | STX1A | 0.12 | 0.02 | enet | 32 | 0.02 | 1.1e-02 | -1.8 | 5.6 | 1.8e-08 | -0.16 | 0.19 | 0.16 | FALSE |
| 3 | GTEx | Spleen | NCF1B | 0.22 | 0.10 | enet | 9 | 0.08 | 5.1e-03 | 5.1 | -5.4 | 6.9e-08 | 0.04 | 0.04 | 0.25 | FALSE |
| 4 | GTEx | Testis | VPS37D | 0.15 | 0.01 | lasso | 5 | 0.03 | 2.7e-02 | -4.9 | -5.5 | 4.7e-08 | -0.02 | 0.11 | 0.16 | FALSE |
| 5 | METSIM | Adipose | TRIM50 | 0.04 | 0.00 | blup | 159 | 0.02 | 7.0e-04 | -4.4 | -7.8 | 4.4e-15 | 0.00 | 0.12 | 0.13 | TRUE |