Hub : Genes

TMEM60

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0850 0.0310 2.4e-04 0.054 NA 0.041 NA 0.049 3.0e-05 NA 2.7e-04 NA 7.3e-05
2 GTEx Adipose Visceral Omentum 0.1980 0.0550 4.4e-07 0.126 NA 0.100 NA 0.111 4.8e-07 NA 7.6e-06 NA 2.3e-06
3 GTEx Artery Tibial 0.0706 0.0303 2.4e-03 0.047 NA 0.022 NA 0.012 1.4e-04 NA 6.6e-03 NA 3.5e-02
4 GTEx Breast Mammary Tissue 0.1330 0.0590 6.3e-03 0.037 NA 0.010 NA 0.037 5.6e-03 NA 9.5e-02 NA 5.4e-03
5 GTEx Breast Mammary Tissue (Female) 0.0732 0.0679 1.6e-01 -0.008 NA 0.010 NA -0.008 6.5e-01 NA 1.5e-01 NA 6.4e-01
6 GTEx Cells Transformed fibroblasts 0.2540 0.0570 8.7e-11 0.195 NA 0.155 NA 0.195 1.4e-14 NA 1.0e-11 NA 1.5e-14
7 GTEx Esophagus Mucosa 0.0570 0.0250 6.1e-03 0.044 NA 0.037 NA 0.040 6.3e-04 NA 1.6e-03 NA 1.0e-03
8 GTEx Lung 0.1160 0.0412 2.1e-04 0.050 NA 0.072 NA 0.052 9.7e-05 NA 3.4e-06 NA 7.9e-05
9 GTEx Muscle Skeletal 0.1061 0.0279 1.6e-08 0.119 NA 0.095 NA 0.123 1.0e-11 NA 1.3e-09 NA 4.6e-12
10 GTEx Nerve Tibial 0.1364 0.0377 2.2e-07 0.136 NA 0.070 NA 0.118 8.0e-10 NA 1.2e-05 NA 1.1e-08
11 GTEx Ovary 0.2300 0.0850 3.4e-03 0.187 NA 0.127 NA 0.123 2.4e-05 NA 5.2e-04 NA 6.4e-04
12 GTEx Pancreas 0.1860 0.0680 1.5e-03 0.032 NA 0.105 NA 0.004 1.7e-02 NA 3.4e-05 NA 2.1e-01
13 GTEx Pituitary 0.1910 0.0740 1.9e-03 0.056 NA 0.018 NA 0.045 1.6e-02 NA 1.2e-01 NA 2.8e-02
14 GTEx Skin Not Sun Exposed Suprapubic 0.1450 0.0610 1.5e-03 0.083 NA 0.024 NA 0.026 2.6e-05 NA 1.7e-02 NA 1.4e-02
15 GTEx Skin Sun Exposed Lower leg 0.1050 0.0330 1.1e-05 0.101 NA 0.042 NA 0.086 1.1e-08 NA 2.2e-04 NA 1.4e-07
16 GTEx Testis 0.1780 0.0770 4.7e-03 -0.006 NA -0.004 NA -0.006 7.3e-01 NA 5.6e-01 NA 8.1e-01
17 GTEx Thyroid 0.0620 0.0240 1.5e-03 0.036 NA 0.032 NA 0.036 8.2e-04 NA 1.7e-03 NA 8.2e-04
18 GTEx Whole Blood 0.0510 0.0190 1.0e-03 0.043 NA 0.032 NA 0.031 7.3e-05 NA 5.4e-04 NA 6.5e-04
19 METSIM Adipose 0.0955 0.0280 1.0e-09 0.074 0.071 0.083 0.077 0.079 2.8e-11 9.1e-11 2.1e-12 1.5e-11 7.0e-12
20 YFS Blood 0.1355 0.0236 0.0e+00 0.157 0.168 0.175 0.169 0.177 8.0e-49 1.7e-52 7.6e-55 5.6e-53 1.8e-55
21 TCGA Breast Invasive Carcinoma 0.0182 0.0099 6.1e-05 0.021 0.018 0.021 NA 0.022 2.6e-05 1.2e-04 3.1e-05 NA 2.3e-05
22 TCGA Cervical Squamous Cell Carcinoma 0.0820 0.0530 4.4e-03 0.060 0.048 0.022 NA 0.045 6.9e-04 2.1e-03 2.9e-02 NA 2.9e-03
23 TCGA Glioblastoma Multiforme 0.0980 0.0590 3.9e-03 0.096 0.086 0.084 NA 0.081 7.7e-04 1.4e-03 1.6e-03 NA 1.9e-03
24 TCGA Head and Neck Squamous Cell Carcinoma 0.0773 0.0412 8.2e-06 0.021 0.043 0.039 NA 0.027 1.7e-03 1.2e-05 3.1e-05 NA 4.9e-04
25 TCGA Kidney Renal Clear Cell Carcinoma 0.0527 0.0304 7.9e-05 0.013 0.017 0.021 NA 0.000 1.1e-02 4.3e-03 1.9e-03 NA 3.3e-01
26 TCGA Kidney Renal Papillary Cell Carcinoma 0.0510 0.0310 4.0e-03 0.017 0.030 0.022 NA 0.019 3.5e-02 7.9e-03 1.9e-02 NA 2.9e-02
27 TCGA Lung Squamous Cell Carcinoma 0.0244 0.0158 2.0e-03 0.027 0.015 0.012 NA 0.012 4.6e-04 6.8e-03 1.5e-02 NA 1.4e-02
28 TCGA Pancreatic Adenocarcinoma 0.1190 0.0720 2.9e-03 0.048 0.025 0.013 NA 0.014 4.4e-03 3.1e-02 8.6e-02 NA 8.4e-02
29 TCGA Prostate Adenocarcinoma 0.0282 0.0182 8.8e-03 0.007 0.014 0.005 NA 0.006 5.6e-02 1.1e-02 8.5e-02 NA 7.7e-02
30 TCGA Stomach Adenocarcinoma 0.2000 0.0940 2.3e-04 0.013 0.029 0.063 NA 0.020 3.4e-02 3.5e-03 2.5e-05 NA 1.2e-02
31 TCGA Thyroid Carcinoma 0.1160 0.0570 1.5e-06 0.059 0.060 0.062 NA 0.051 2.1e-06 1.8e-06 1.1e-06 NA 9.1e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31
Bipolar Disorder (2018) 0.1 0.2 1.5 -0.4 -0.6 -0.7 -0.0 0.0 -0.3 -0.2 -1.2 0.2 -0.2 -1.0 0.1 -0.1 -0.2 -0.3 0.0 -1.0 -0.5 -0.4 0.1 -0.1 0.1 -0.4 0.7 0.3 0.2 0.2 0.4 0.4 -0.0 0.1
Bipolar Disorder or Schizophrenia 0.1 0.3 1.4 0.6 0.3 0.1 1.2 0.0 0.6 0.5 -0.4 -0.6 0.5 0.4 0.2 0.6 0.7 0.5 0.0 0.2 0.4 0.6 0.7 0.6 0.2 0.6 0.7 0.2 0.3 0.5 0.3 0.4 0.3 0.6
Depressed Affect (Nagel 2018) 0.3 0.5 2.4 0.3 0.3 0.2 -1.1 0.0 0.4 0.4 0.5 -0.0 0.0 0.3 0.3 -0.7 0.7 0.4 0.0 0.4 0.2 -0.4 0.5 0.4 1.3 -1.3 1.2 1.3 1.3 0.6 1.2 1.6 0.3 0.3
Depression (Nagel 2018) 0.2 0.3 1.0 0.4 -0.1 0.2 -0.1 0.0 0.3 0.3 0.5 -0.2 0.2 0.2 0.6 0.2 0.5 0.3 0.0 -0.1 0.1 0.6 0.5 0.8 1.0 -0.0 0.8 0.9 0.9 0.7 0.5 0.9 0.3 0.1
Intelligence (Savage-Jansen 2018) 0.3 0.8 4.7 1.2 0.9 -1.2 0.1 0.0 0.9 0.9 2.2 -0.9 1.1 0.6 0.4 1.4 0.8 0.9 0.0 0.6 0.9 1.2 1.0 0.9 0.5 1.3 0.6 0.6 0.6 0.8 0.7 0.6 0.2 0.8
Neuroticism (Nagel 2018) 1.1 2.5 5.7 1.6 1.4 0.7 0.3 0.0 1.7 1.7 1.6 -1.4 1.4 1.3 1.3 0.9 1.9 1.7 0.0 1.3 1.5 1.1 1.9 1.8 2.3 0.1 2.2 2.2 2.3 2.0 2.2 2.4 1.3 1.4
Schizophrenia (2018) 0.3 0.6 2.5 1.1 0.8 0.6 1.6 0.0 0.9 0.9 0.4 -0.9 0.8 1.2 0.1 0.9 1.0 0.9 0.0 1.0 0.9 1.0 0.8 0.8 0.2 1.1 0.3 0.2 0.2 0.5 0.1 0.2 0.4 0.7
Schizophrenia vs Biploar Disorder 1.6 2.1 3.9 1.9 1.5 1.6 2.0 0.0 1.8 1.8 1.7 -1.8 1.8 0.8 0.5 1.5 1.5 1.9 0.0 1.2 1.5 1.5 1.4 1.6 1.7 1.0 1.0 1.4 1.7 1.9 1.5 0.8 1.1 1.4
Worry (Nagel 2018) 1.5 3.1 6.9 1.6 1.9 1.4 1.0 0.0 1.7 1.7 1.5 -1.6 1.6 2.3 1.7 1.4 1.6 1.7 0.0 2.2 2.0 1.6 1.8 2.1 2.6 0.4 2.0 2.4 2.6 2.3 2.1 1.8 1.0 1.4
Alzheimer’s Disease (in mother) 1.1 1.2 2.8 -1.4 -1.4 -1.0 -1.5 0.0 -1.2 -1.2 -0.5 1.3 -1.3 -1.7 0.0 -1.5 -1.2 -1.2 0.0 -1.5 -1.4 -1.5 -1.4 -1.3 -0.7 -1.6 -0.5 -0.6 -0.7 -1.1 -0.6 -0.7 -0.4 -0.8
Alzheimer’s Disease (in father) 0.3 0.3 1.7 -0.3 -0.4 -0.6 -0.5 0.0 -0.4 -0.4 0.5 0.4 -0.4 -1.3 -0.2 -0.7 -0.8 -0.3 0.0 -0.6 -0.4 -0.7 -0.6 -0.8 -0.5 -0.7 -0.4 -0.1 -0.4 -0.5 -0.0 -0.7 0.5 0.3
Alzheimer’s Disease (including proxy) 1.2 1.7 4.6 -1.5 -1.2 -1.0 -1.3 0.0 -1.4 -1.4 -0.6 1.6 -1.5 -2.1 -0.6 -2.1 -1.5 -1.3 0.0 -1.4 -1.5 -1.9 -1.4 -1.7 -0.9 -2.1 -0.6 -0.5 -0.9 -1.5 -0.4 -0.5 -0.3 -0.8
Crohns Disease (2017) 0.2 0.5 1.9 -0.7 -1.1 -0.5 -0.7 0.0 -0.6 -0.5 -1.1 0.8 -0.5 -1.1 0.2 -1.0 -0.9 -0.5 0.0 -0.7 -1.1 -0.8 -0.6 -0.2 0.8 -1.4 0.2 0.7 0.5 -0.2 0.3 0.8 -0.8 -0.8
Irritable Bowel Disease (IBD) 0.3 0.7 4.2 0.8 0.6 0.2 0.2 0.0 0.7 0.7 -0.2 -0.5 0.7 0.2 0.9 0.3 0.5 0.7 0.0 0.8 0.6 0.1 1.0 0.7 1.4 -0.2 1.4 1.4 1.3 0.9 1.5 2.1 0.4 0.5
Ulcerative Colitis (UC) 1.6 3.0 6.6 2.1 2.1 0.8 1.2 0.0 1.8 1.9 1.2 -1.7 1.8 1.5 1.5 1.4 1.8 1.8 0.0 2.0 2.1 0.9 2.2 1.3 1.7 0.7 2.2 2.1 1.9 1.8 2.5 2.6 1.7 2.0
Major Depression (MDD) 1.1 1.3 3.2 1.1 1.4 0.3 1.4 0.0 1.2 1.2 1.5 -1.1 1.1 1.5 0.9 1.1 1.4 1.1 0.0 1.2 1.3 1.8 1.1 1.7 1.4 1.2 0.5 0.9 1.2 1.1 0.5 1.1 -0.6 0.0
Reaction Time 1.0 1.8 4.5 1.4 1.5 2.1 1.1 0.0 1.4 1.4 0.7 -1.5 1.6 1.7 1.6 1.4 1.3 1.6 0.0 1.5 1.6 1.5 1.2 1.5 1.5 0.8 0.8 1.5 1.6 1.6 1.2 0.3 1.2 1.4
Verbal and Numeric Reasoning (VNR) 0.8 1.9 4.7 1.8 1.7 0.7 0.7 0.0 1.7 1.7 2.2 -1.8 1.8 1.2 1.0 2.1 1.7 1.7 0.0 1.1 1.5 1.9 1.6 1.6 0.9 1.8 0.6 0.7 1.0 1.4 0.8 0.4 0.8 1.3
Breast Cancer 0.3 0.6 3.6 0.8 0.2 1.8 0.7 0.0 0.5 0.5 1.9 -0.4 0.5 -0.5 1.4 0.2 0.3 0.5 0.0 -0.4 0.3 0.2 0.4 0.1 1.0 -0.4 0.6 1.6 1.0 0.5 1.1 0.8 0.4 0.8
Ovarian Cancer 0.4 0.5 4.5 0.6 -0.1 -0.1 -0.1 0.0 0.4 0.4 1.8 -0.3 0.1 -0.5 -0.8 0.0 0.7 0.3 0.0 -0.9 0.0 0.4 0.3 0.4 -0.1 0.5 1.4 0.4 0.1 0.4 0.5 0.8 2.1 1.1
Prostate Cancer 0.2 0.3 2.4 0.1 0.6 -0.7 0.2 0.0 0.4 0.4 -0.2 -0.3 0.3 1.5 -0.4 0.4 0.5 0.2 0.0 1.3 0.6 0.5 0.4 0.5 -0.2 1.0 0.5 -0.6 -0.3 0.1 -0.1 0.9 0.2 -0.1
Age at First Birth 1.2 1.7 4.2 1.1 1.2 1.4 1.3 0.0 1.7 1.7 1.6 -1.7 1.6 0.7 -0.3 1.6 1.6 1.6 0.0 1.0 1.3 1.8 1.5 1.3 0.2 2.0 1.0 0.5 0.5 1.1 0.7 0.7 1.6 1.8
Bipolar Disorder (2011) 0.3 0.3 2.0 0.1 0.2 1.1 0.7 0.0 0.2 0.2 -0.5 -0.0 0.2 0.0 -0.4 0.0 0.6 0.1 0.0 0.2 0.2 -0.6 0.7 -0.1 0.5 -0.5 1.1 1.0 0.6 0.1 1.0 1.4 0.1 0.3
Body Mass Index (BMI) (2010) 2.5 3.4 7.5 -1.8 -2.6 -2.7 -1.8 0.0 -1.7 -1.7 -1.8 1.7 -1.6 -2.7 -2.2 -1.5 -1.6 -1.7 0.0 -2.6 -2.4 -1.5 -1.6 -1.5 -1.4 -1.0 -1.8 -2.0 -1.6 -1.7 -1.8 -1.1 -2.3 -2.4
Coronary Artery Disease (CAD) 1.1 1.4 3.6 1.1 1.1 0.3 0.7 0.0 1.5 1.5 1.9 -1.5 1.4 0.7 1.0 1.4 1.6 1.5 0.0 1.0 1.1 1.4 1.3 1.0 -0.1 1.8 1.0 0.6 0.2 0.6 0.7 0.8 1.6 1.8
Crohns Disease (2012) 0.7 1.2 3.2 -1.6 -1.5 -1.0 -0.5 0.0 -1.1 -1.1 -1.8 1.2 -1.2 -1.5 -1.0 -1.5 -1.3 -1.1 0.0 -1.2 -1.6 -1.0 -1.1 -0.5 0.1 -1.3 -0.5 -0.6 -0.3 -0.6 -0.7 0.1 -1.5 -1.7
Mean Putamen Volume 1.0 1.1 2.9 0.9 1.4 0.8 0.9 0.0 0.9 0.9 1.7 -1.1 1.1 1.4 1.4 1.5 0.9 0.9 0.0 1.4 1.3 1.6 0.9 1.2 1.0 1.4 0.4 0.8 0.9 1.1 0.5 0.6 -0.4 0.1
Fasting Glucose 1.6 1.9 5.2 -1.2 -1.4 -1.9 -1.1 0.0 -1.5 -1.5 -1.0 1.1 -1.5 -0.9 -1.0 -0.8 -1.3 -1.6 0.0 -0.9 -1.2 -1.3 -1.3 -1.6 -2.3 -0.1 -1.4 -2.2 -2.3 -1.8 -1.7 -1.5 -1.2 -1.0
HbA1C 0.4 0.4 2.6 -0.6 -1.3 -0.4 -1.6 0.0 0.2 0.2 -0.2 -0.4 0.0 -1.5 0.1 -0.0 -0.3 0.3 0.0 -1.1 -1.1 0.5 -0.3 0.0 -0.4 0.5 -0.9 -0.5 -0.5 -0.3 -0.8 -0.8 -0.3 -0.1
HDL Cholesterol 1.2 2.0 4.0 -1.4 -1.5 -0.6 -1.5 0.0 -1.5 -1.4 -0.4 1.5 -1.5 -2.0 -0.2 -1.8 -1.7 -1.4 0.0 -1.6 -1.7 -2.0 -1.7 -2.0 -1.5 -1.7 -1.4 -1.1 -1.4 -1.8 -1.0 -1.3 -0.8 -0.9
LDL Cholesterol 0.9 1.4 3.8 -1.2 -0.8 -0.7 -1.3 0.0 -1.5 -1.5 -1.9 1.6 -1.4 0.1 -1.6 -1.7 -1.1 -1.6 0.0 -0.0 -1.1 -1.8 -1.2 -1.1 -0.1 -1.9 -0.2 -0.6 -0.3 -0.9 -0.5 0.4 -1.6 -1.9
Lupus 2.5 3.8 8.1 2.0 2.1 2.7 1.3 0.0 2.0 1.9 1.4 -1.9 1.8 2.1 1.0 1.4 2.3 1.8 0.0 1.5 2.0 2.0 2.0 2.4 2.1 1.4 2.7 2.0 2.1 2.3 1.9 2.9 2.2 1.7
Neuroticism (2016) 0.9 1.3 5.7 0.8 0.7 -0.2 0.3 0.0 1.0 1.0 1.6 -0.7 0.8 0.5 1.1 0.1 1.1 1.0 0.0 0.4 0.8 0.2 1.1 1.2 2.4 -1.0 1.5 2.0 2.2 1.4 1.8 1.9 -0.1 0.2
Primary Biliary Cirrhosis 0.3 0.5 1.7 0.6 -0.3 0.3 0.1 0.0 0.6 0.6 -0.5 -0.5 0.5 -0.6 -0.7 0.3 0.6 0.6 0.0 -0.8 -0.3 0.3 0.4 1.0 1.1 -0.1 1.3 1.0 1.1 1.1 0.8 0.8 1.1 0.8
Rheumatoid Arthritis 0.8 1.2 2.6 -1.2 -1.2 -0.3 -0.1 0.0 -1.3 -1.2 -1.1 1.3 -1.3 -1.5 -0.5 -1.4 -1.2 -1.3 0.0 -1.5 -1.1 -1.6 -1.3 -1.6 -1.0 -1.3 -0.7 -0.7 -1.0 -1.2 -0.6 -0.4 -0.0 -0.7
Schizophrenia (2014) 0.5 1.0 2.0 1.1 1.1 0.8 1.4 0.0 1.1 1.1 1.0 -1.2 1.2 1.2 0.3 1.3 1.0 1.1 0.0 1.2 1.2 1.3 1.2 1.1 0.7 1.0 1.0 1.0 0.9 1.1 0.8 0.5 0.9 1.2
Triglycerides 0.7 1.2 5.6 0.8 0.8 -0.7 0.6 0.0 1.0 1.0 0.5 -0.8 0.8 0.9 -0.4 0.3 1.5 0.8 0.0 0.9 1.1 0.5 1.3 0.8 0.8 0.3 2.2 1.3 1.0 0.8 1.5 2.4 1.9 1.4
Type 2 Diabetes (T2D) (2012) 0.4 0.5 2.6 0.7 0.8 0.6 -0.0 0.0 0.6 0.6 0.8 -0.8 0.5 1.1 0.2 0.7 0.5 0.7 0.0 1.6 1.0 1.0 0.3 0.8 -0.4 1.1 0.1 -0.5 -0.3 0.2 -0.4 -0.5 1.0 0.8
Ulcerative Colitis 0.3 0.4 2.1 0.7 0.5 -0.5 0.4 0.0 0.3 0.3 0.3 -0.2 0.2 0.1 -0.1 -0.1 0.5 0.2 0.0 0.3 0.7 -0.7 0.8 -0.0 0.7 -0.5 1.1 1.1 0.8 0.4 1.3 1.5 0.7 0.7
Blood Eosinophil Count 4.4 34.0 51.4 7.2 7.1 5.0 4.9 0.0 6.2 6.2 4.7 -6.0 6.4 6.2 4.8 5.5 6.6 6.1 0.0 6.2 6.9 4.9 6.9 5.8 5.7 3.6 6.7 6.3 6.2 6.4 6.8 6.5 5.2 5.9
Blood Platelet Count 0.2 2.6 7.2 1.3 1.9 0.8 1.8 0.0 1.5 1.5 1.6 -1.4 1.4 1.0 1.1 0.7 1.2 1.5 0.0 1.5 1.6 0.7 1.4 0.8 2.4 -0.3 1.9 2.7 2.5 1.9 2.7 2.2 1.5 2.0
Blood Red Count 0.2 2.1 5.6 -1.8 -2.1 -1.8 -1.5 0.0 -1.6 -1.6 -1.0 1.7 -1.7 -2.3 -0.8 -1.7 -1.6 -1.6 0.0 -2.4 -1.9 -1.4 -1.5 -1.5 -1.2 -1.5 -0.6 -0.9 -1.2 -1.4 -0.9 -0.9 -0.0 -0.8
Blood White Count 0.1 1.0 3.3 1.2 1.4 0.5 1.2 0.0 0.6 0.6 1.1 -0.3 0.6 1.6 1.2 -0.1 0.8 0.6 0.0 1.6 1.2 -0.2 1.0 0.2 1.2 -0.9 1.2 1.8 1.3 0.6 1.6 1.4 0.6 0.9
Heel T-Score 0.1 0.5 1.8 -0.5 -0.5 -1.0 0.3 0.0 -0.3 -0.3 -0.0 0.4 -0.2 -1.3 1.2 -0.6 -0.7 -0.1 0.0 -0.7 -0.3 -1.2 -0.5 -1.3 -0.5 -1.2 -1.0 -0.0 -0.3 -0.8 0.3 -1.1 -0.3 0.2
BMI 3.6 20.9 30.9 -5.2 -5.1 -5.4 -3.2 0.0 -5.4 -5.3 -4.1 5.5 -5.5 -4.2 -2.8 -5.4 -5.2 -5.4 0.0 -4.1 -5.2 -5.5 -5.1 -5.6 -4.2 -4.7 -4.1 -3.8 -4.4 -5.4 -3.9 -3.3 -3.9 -4.5
Height 1.3 24.4 46.6 -5.4 -5.8 -5.2 -4.8 0.0 -5.4 -5.3 -3.8 5.5 -5.5 -4.9 -5.1 -4.2 -4.5 -5.7 0.0 -4.8 -5.6 -4.6 -4.7 -5.9 -6.8 -1.9 -4.1 -6.0 -6.8 -6.5 -5.5 -3.2 -3.0 -4.1
Waist Hip Ratio (WHR) 13.7 61.6 102.0 9.6 8.6 6.9 7.8 0.0 9.0 9.0 6.9 -9.7 9.6 7.5 6.0 10.1 8.6 9.2 0.0 7.0 9.2 9.6 8.7 9.5 7.5 8.3 6.1 6.5 7.8 9.5 6.8 4.8 4.8 6.9
Systolic Blood Pressure 1.8 9.0 18.5 3.6 2.9 4.1 4.3 0.0 3.5 3.4 1.0 -4.0 3.8 1.9 3.0 4.3 2.8 3.7 0.0 2.0 3.4 4.0 2.8 4.0 3.0 3.5 1.1 1.8 3.0 4.0 2.0 0.4 1.1 2.2
Smoking Status 0.3 0.6 3.6 0.4 0.1 -0.5 -0.4 0.0 0.1 0.1 1.9 0.1 0.1 -0.4 1.8 -0.8 0.1 0.2 0.0 -0.2 0.0 -0.9 0.0 -0.4 1.1 -1.9 0.3 1.7 1.1 0.1 1.3 0.3 -0.0 0.5
Allergy or Eczema 0.8 2.0 5.1 1.7 1.9 -0.5 1.7 0.0 1.4 1.4 2.0 -1.6 1.5 2.2 0.2 1.8 1.4 1.4 0.0 2.1 1.9 1.9 1.3 1.5 0.4 2.3 1.0 0.5 0.6 1.3 0.5 0.5 1.5 1.4
Cardiovascular Disease 0.9 3.1 8.6 2.2 1.9 1.1 2.7 0.0 2.0 2.0 1.0 -2.4 2.3 1.5 0.9 2.9 1.9 2.1 0.0 1.1 2.1 2.6 1.9 2.4 1.4 2.6 0.5 0.5 1.4 2.2 0.9 0.4 0.4 1.1
Hypothyroidism (self reported) 4.6 10.5 19.5 -3.8 -4.0 -3.7 -2.0 0.0 -3.7 -3.6 -3.4 4.0 -4.2 -3.2 -3.2 -4.4 -3.2 -3.9 0.0 -3.4 -3.8 -3.9 -3.3 -4.0 -3.4 -3.0 -1.6 -2.6 -3.4 -3.9 -2.6 -1.1 -0.8 -2.2
Respiratory disease 0.9 2.0 6.2 -1.6 -1.6 -1.4 -0.1 0.0 -1.4 -1.4 -0.9 1.6 -1.9 -1.6 -2.3 -2.5 -1.0 -1.5 0.0 -1.5 -1.4 -1.9 -1.5 -1.9 -1.7 -1.5 -0.5 -1.1 -1.6 -1.9 -0.8 -0.1 -0.1 -0.6
Type 2 Diabetes (T2D) (2018) 0.8 1.5 5.3 1.2 1.4 -0.7 0.3 0.0 1.2 1.2 2.3 -1.3 1.2 1.3 1.1 1.6 1.3 1.2 0.0 1.3 1.2 1.8 1.5 1.5 1.0 1.4 1.2 1.2 1.1 1.3 0.9 0.9 1.2 1.2
Lung FEV1/FVC ratio 0.2 0.8 3.4 -0.7 0.2 -0.3 -0.4 0.0 -0.6 -0.6 -0.5 0.4 -0.5 0.4 -1.8 0.0 -0.8 -0.6 0.0 1.2 -0.0 -0.3 -0.6 -0.9 -1.1 0.4 -1.6 -1.2 -1.2 -1.1 -1.1 -1.2 -1.8 -1.1
Lung FVC 0.2 0.9 4.7 -0.8 -0.3 0.2 -1.2 0.0 -0.3 -0.3 -1.0 0.1 -0.2 -0.2 -1.3 0.6 -0.2 -0.4 0.0 -0.4 -0.6 0.7 -0.4 0.1 -1.8 1.8 -0.8 -2.2 -1.7 -0.6 -1.8 -1.1 0.1 -0.7
Neuroticism 0.7 1.7 5.9 1.0 1.4 0.1 -0.4 0.0 0.9 0.9 2.0 -0.6 0.8 1.9 0.8 0.2 1.1 0.9 0.0 1.5 1.1 0.5 1.1 1.2 2.4 -1.0 1.6 2.4 2.3 1.5 1.8 1.9 0.5 0.7
Chronotype (morning person) 0.2 0.4 2.3 0.7 0.2 0.3 0.8 0.0 0.4 0.4 0.4 -0.7 0.7 0.1 -0.1 1.5 0.1 0.4 0.0 0.1 0.4 1.0 0.2 0.7 0.5 1.1 -0.8 -0.3 0.4 0.8 -0.2 -0.7 -1.4 -0.7
Hair Pigment 0.1 2.2 5.5 1.6 1.4 1.1 2.3 0.0 1.8 1.7 0.3 -1.6 1.5 0.4 1.9 1.2 2.2 1.6 0.0 0.8 1.7 1.0 2.0 0.9 0.2 1.6 1.9 0.8 0.6 1.0 1.6 1.8 2.3 2.2
Tanning 0.4 4.9 13.0 -2.3 -2.9 -1.3 -2.3 0.0 -2.0 -2.0 -1.1 2.3 -2.3 -3.6 -3.4 -3.3 -2.2 -1.9 0.0 -3.4 -3.0 -3.0 -2.5 -2.5 -0.8 -3.5 -1.5 -0.5 -1.0 -2.1 -0.8 -1.2 -1.0 -1.2
Hand grip strength (left) 2.2 5.9 12.4 -3.0 -2.8 -2.7 -2.1 0.0 -2.4 -2.4 -1.2 2.7 -2.6 -3.5 -0.9 -2.8 -2.4 -2.5 0.0 -2.8 -3.0 -3.0 -2.4 -3.3 -3.0 -2.1 -2.1 -2.2 -2.9 -3.4 -1.9 -1.6 -1.4 -1.6
Number of treatments/medications taken 0.1 0.2 1.8 0.4 0.1 0.5 1.3 0.0 -0.1 -0.1 -0.1 0.1 -0.3 -0.1 0.8 0.0 0.3 -0.2 0.0 -0.0 0.5 0.2 0.1 -0.4 -0.8 0.6 0.0 -0.0 -0.6 -0.4 -0.1 -0.2 1.1 0.7
Average weekly spirits intake 1.0 1.2 3.0 -1.4 -0.9 -0.7 -0.6 0.0 -1.2 -1.2 -1.2 1.1 -1.1 -0.7 -0.0 -0.7 -1.2 -1.1 0.0 -0.7 -1.1 -0.8 -1.1 -1.1 -1.2 -0.5 -1.7 -1.4 -1.3 -1.3 -1.4 -1.6 -1.7 -1.4
Sensitivity / hurt feelings 0.2 0.4 2.3 0.3 -0.3 -0.2 -0.2 0.0 0.3 0.3 0.5 -0.1 0.1 -0.6 0.1 -0.8 0.0 0.4 0.0 -0.7 -0.2 -0.8 -0.1 0.1 1.2 -1.5 0.7 1.1 1.1 0.4 1.2 0.9 0.0 0.3
Frequency of depressed mood in last 2 weeks 0.4 0.6 3.4 0.7 0.3 -0.0 -0.3 0.0 0.6 0.6 1.8 -0.5 0.5 0.6 0.9 0.3 0.9 0.5 0.0 0.1 0.6 1.0 0.7 1.0 0.9 0.4 1.1 1.2 0.9 0.7 0.7 1.2 0.8 0.7
Hearing difficulty/problems: Yes 0.3 0.4 1.3 -0.5 -1.0 -0.8 -0.2 0.0 -0.8 -0.7 -0.0 0.8 -0.7 -1.1 -1.1 -0.6 -0.8 -0.7 0.0 -1.1 -1.0 -0.6 -0.7 -0.5 -0.2 -0.7 -0.4 -0.3 -0.3 -0.5 -0.4 -0.4 -0.6 -0.6
Relative age of first facial hair 1.1 2.2 4.2 1.6 1.6 1.7 1.2 0.0 1.6 1.6 0.7 -1.6 1.5 1.2 1.4 0.9 1.4 1.6 0.0 1.3 1.5 1.0 1.5 1.5 2.0 0.4 1.9 1.9 2.1 1.9 2.0 1.9 1.3 1.5
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 4.0 1.3 1.3 -0.6 1.0 0.0 1.0 1.0 2.0 -1.1 1.2 1.2 1.4 1.4 1.2 0.9 0.0 1.4 1.5 1.2 1.3 1.1 0.5 1.5 1.2 0.5 0.6 1.0 0.9 1.3 0.5 0.6
Ever used hormone-replacement therapy (HRT) 0.8 1.0 4.2 -1.0 -0.8 -2.0 -0.6 0.0 -1.1 -1.1 -0.7 1.2 -1.2 -0.6 -1.5 -1.2 -1.0 -1.2 0.0 -0.5 -1.0 -0.9 -0.8 -1.0 -0.9 -0.5 -0.8 -0.8 -1.1 -1.3 -0.9 0.0 -1.6 -1.4
Ever had hysterectomy (womb removed) 0.7 0.8 1.4 0.8 0.9 0.7 1.0 0.0 1.0 1.0 1.0 -1.0 1.1 0.8 0.9 0.9 0.9 1.0 0.0 1.0 1.0 0.7 1.1 0.7 1.0 0.6 0.8 1.1 1.0 0.8 1.1 1.2 0.1 0.8
Systolic blood pressure, automated reading 0.1 0.3 2.9 0.3 -0.1 0.3 1.7 0.0 -0.0 -0.0 -1.4 -0.3 0.2 -0.0 0.3 0.4 -0.2 0.1 0.0 -0.2 0.2 -0.1 -0.2 0.4 0.5 0.1 -0.6 -0.5 0.3 0.5 -0.1 -0.5 -1.3 -0.9
Eye problems/disorders: Diabetes related eye disease 2.1 2.3 3.8 1.8 1.6 0.9 1.2 0.0 1.6 1.6 1.9 -1.7 1.7 1.8 0.4 1.7 1.5 1.6 0.0 1.8 1.8 1.9 1.5 1.6 1.4 1.4 1.4 1.7 1.5 1.7 1.3 0.9 1.4 1.8
Angina 0.4 0.5 1.2 1.1 -0.0 0.2 0.5 0.0 0.7 0.7 0.7 -0.7 0.6 -0.0 0.9 0.7 1.0 0.6 0.0 -0.8 0.4 0.9 0.8 0.7 0.3 0.8 1.0 0.6 0.5 0.6 0.7 1.0 0.8 0.9
Medication for hormone replacement therapy 0.7 0.8 3.8 -0.9 -0.4 -0.8 -1.3 0.0 -0.8 -0.8 -0.7 1.2 -1.2 -0.0 -0.5 -1.9 -0.5 -0.9 0.0 0.4 -0.8 -1.6 -0.5 -1.2 -0.1 -1.9 -0.1 0.5 -0.2 -1.1 0.0 0.9 -0.5 -0.5
Vitamin and mineral supplements 1.0 1.3 5.1 1.2 -0.0 1.1 1.7 0.0 1.0 1.0 0.9 -0.8 0.9 -0.3 0.3 -0.1 0.7 1.0 0.0 -0.3 0.5 0.3 0.8 0.9 2.1 -0.8 1.5 2.3 2.0 1.4 2.0 1.9 0.8 1.2
Supplements: Zinc 1.0 1.1 2.3 -1.0 -1.3 -1.5 -1.5 0.0 -1.0 -1.0 -0.8 1.2 -1.1 -1.4 -0.7 -1.2 -0.7 -1.1 0.0 -1.3 -1.4 -1.4 -0.8 -1.2 -1.3 -0.7 -0.3 -1.2 -1.3 -1.3 -0.9 0.1 -0.2 -0.8
Medication: Co-codamol 0.1 0.2 1.2 -0.4 -0.2 -1.1 -0.7 0.0 -0.5 -0.5 -0.4 0.4 -0.4 -0.1 -0.7 -0.0 -0.4 -0.6 0.0 -0.1 -0.2 -0.3 -0.2 -0.1 -0.4 -0.1 0.5 -0.6 -0.3 0.0 -0.1 0.0 0.2 -0.1
Medication: Metformin 0.7 1.0 6.7 0.7 0.8 -0.6 0.2 0.0 1.0 1.0 2.6 -0.9 0.9 0.7 1.6 1.2 1.1 0.9 0.0 0.7 0.8 1.3 1.3 0.6 0.1 1.2 0.6 0.9 0.3 0.4 0.5 0.6 1.1 1.3
Diabetes (father) 0.6 0.7 3.4 0.6 -0.2 0.6 0.5 0.0 0.7 0.7 1.2 -0.7 0.6 -0.4 1.1 -0.1 0.3 0.9 0.0 0.0 0.2 0.3 0.3 0.6 1.9 -1.0 0.4 1.8 1.7 1.1 1.3 0.3 0.5 0.8
Diabetes (mother) 0.5 0.7 2.0 -1.0 -0.7 -0.9 -0.5 0.0 -0.8 -0.8 -0.7 0.6 -0.6 -1.0 -1.0 -0.5 -1.1 -0.7 0.0 -0.5 -0.7 -0.4 -0.9 -0.9 -0.9 -0.1 -1.4 -0.8 -1.0 -1.0 -1.0 -1.4 -1.1 -0.8
Severe depression (siblings) 1.0 1.1 3.8 1.3 1.1 0.0 0.9 0.0 1.2 1.2 0.6 -1.0 1.1 0.7 0.3 0.8 1.4 1.1 0.0 0.7 1.0 0.8 1.3 0.8 0.1 1.0 1.9 0.5 0.5 0.9 1.2 1.4 1.9 1.6
Pack years adult smoking proportion 1.2 1.8 5.1 1.9 0.9 0.5 1.7 0.0 1.2 1.2 0.3 -1.0 1.2 1.1 -0.0 0.8 1.5 1.2 0.0 0.5 1.0 0.7 1.5 1.1 1.9 -0.2 2.1 2.3 2.0 1.6 2.1 2.1 1.3 1.4
Impedance of leg (right) 0.4 2.1 6.8 0.8 2.1 1.9 1.5 0.0 1.5 1.5 0.9 -1.6 1.3 2.2 -0.6 1.2 1.4 1.5 0.0 2.4 1.8 1.5 1.3 1.4 0.0 1.9 1.5 0.3 0.4 1.2 0.7 0.6 2.6 2.1
Leg fat-free mass (left) 4.3 22.5 34.3 -5.1 -5.8 -5.4 -4.3 0.0 -5.4 -5.4 -3.3 5.7 -5.5 -5.5 -3.4 -5.2 -5.0 -5.5 0.0 -5.4 -5.7 -5.5 -5.0 -5.9 -4.7 -4.5 -4.0 -3.9 -4.8 -5.7 -4.1 -3.3 -3.5 -4.2
Trunk fat percentage 5.4 21.7 35.2 -5.7 -4.9 -4.7 -3.3 0.0 -5.8 -5.7 -4.7 5.9 -5.8 -3.6 -4.6 -5.7 -5.4 -5.8 0.0 -3.5 -5.2 -5.7 -5.3 -5.6 -4.4 -4.9 -3.2 -3.9 -4.5 -5.3 -3.9 -3.1 -2.7 -4.2
Hand grip strength (right) 2.2 6.1 13.4 -2.9 -2.9 -2.5 -2.3 0.0 -2.4 -2.4 -1.3 2.8 -2.7 -3.7 -2.1 -3.3 -2.4 -2.5 0.0 -3.0 -3.2 -3.3 -2.4 -3.4 -2.6 -2.7 -1.7 -1.8 -2.5 -3.3 -1.5 -0.9 -1.2 -1.5
Townsend deprivation index at recruitment 0.3 0.4 2.3 -0.5 -1.2 -0.4 -0.7 0.0 -0.7 -0.6 0.1 0.7 -0.8 -0.7 0.5 -1.0 -0.6 -0.6 0.0 -1.5 -1.1 -0.5 -1.0 -0.5 -0.2 -0.9 0.0 -0.1 -0.2 -0.3 -0.3 -0.2 0.3 -0.1
Current tobacco smoking 0.3 0.5 2.2 1.1 0.3 0.4 0.5 0.0 0.6 0.6 0.7 -0.6 0.7 -0.1 0.3 0.0 0.7 0.7 0.0 0.0 0.5 -0.3 0.7 0.2 1.2 -0.9 0.8 1.5 1.3 0.7 1.4 0.7 0.3 0.8
Average weekly fortified wine intake 0.4 0.4 2.4 -0.2 -0.0 -1.5 -1.0 0.0 -0.4 -0.5 0.3 0.5 -0.5 -0.1 0.3 -1.0 -0.4 -0.4 0.0 0.5 -0.0 -1.4 -0.4 -1.3 -0.8 -1.1 -0.5 -0.4 -0.7 -1.0 -0.0 -0.4 -0.2 -0.0
Maternal smoking around birth 0.7 1.0 2.5 -0.6 -0.8 0.2 0.6 0.0 -1.2 -1.1 -1.2 1.2 -1.1 -0.8 -1.0 -1.4 -1.2 -1.1 0.0 -0.7 -0.8 -1.4 -1.4 -1.6 -1.1 -1.4 -0.9 -0.7 -1.0 -1.2 -0.6 -1.0 -0.1 -0.4
Fed-up feelings 0.5 0.9 4.8 -0.7 -0.9 -0.8 -2.2 0.0 -1.1 -1.1 -0.1 1.4 -1.3 -0.4 -0.9 -1.6 -0.7 -1.1 0.0 -0.6 -0.9 -1.5 -0.8 -1.1 -0.2 -1.9 0.2 0.1 -0.2 -0.8 -0.1 0.3 -0.1 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.4 0.3 0.1 0.4 -0.2 0.0 0.3 0.3 0.4 -0.2 0.2 0.1 0.0 -0.0 0.3 0.3 0.0 -0.1 0.0 0.2 0.3 0.5 0.6 -0.3 0.6 0.5 0.6 0.4 0.5 0.4 0.2 0.2
Relative age voice broke 0.4 0.7 2.5 0.5 1.2 0.0 -0.4 0.0 0.5 0.5 0.5 -0.2 0.5 1.4 0.4 -0.2 0.6 0.5 0.0 1.6 0.9 -0.5 0.8 -0.1 0.6 -0.7 1.3 1.2 0.8 0.4 1.4 1.5 1.1 1.0
Taking other prescription medications 0.3 0.5 2.8 0.7 0.5 1.6 1.7 0.0 0.6 0.6 -0.6 -0.5 0.4 0.3 0.4 0.1 0.7 0.6 0.0 0.6 0.7 0.1 0.5 0.1 0.2 0.0 0.7 0.7 0.4 0.4 1.0 0.6 1.3 1.2
Age when periods started (menarche) 0.2 0.4 2.1 0.1 -0.2 -1.1 -0.8 0.0 0.1 0.1 0.5 0.1 -0.2 -0.5 -0.7 -1.0 0.2 0.1 0.0 -0.2 -0.2 -1.2 -0.0 -0.4 0.7 -1.4 0.7 0.7 0.7 0.1 1.0 1.2 0.1 0.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.2 -0.4 -0.6 0.2 0.1 0.0 -0.8 -0.8 -0.7 0.7 -0.6 -0.6 -0.4 -0.6 -0.9 -0.7 0.0 -0.5 -0.6 -0.6 -0.7 -0.3 0.5 -1.1 -0.6 0.3 0.3 -0.1 -0.0 -0.5 -1.1 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 1.7 1.0 0.9 0.1 0.1 0.0 1.0 1.0 1.0 -0.9 1.0 0.3 1.3 0.4 0.9 1.1 0.0 0.4 1.0 0.0 0.9 0.2 0.9 -0.3 0.3 1.1 1.0 0.6 1.3 0.3 0.5 1.2
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.1 -0.3 -0.5 -0.5 -0.7 0.0 -0.3 -0.2 -0.9 0.2 -0.4 -0.2 -0.8 -0.2 -0.6 -0.2 0.0 -0.9 -0.6 0.0 -0.4 0.7 1.0 -0.5 0.2 0.1 0.8 0.9 -0.0 -0.1 -0.1 -0.6
Qualifications: CSEs or equivalent 2.0 2.6 5.2 -1.9 -1.7 -1.1 -2.3 0.0 -1.9 -1.9 -0.8 2.0 -2.0 -1.2 -0.3 -2.0 -1.8 -1.8 0.0 -1.1 -1.9 -1.7 -1.8 -2.2 -2.2 -1.6 -1.1 -1.3 -2.0 -2.1 -1.5 -1.8 0.4 -0.4
Serious illness, injury or assault to yourself 1.3 1.6 3.4 1.6 0.6 1.8 1.4 0.0 1.7 1.8 0.9 -1.8 1.6 -0.6 1.6 1.2 1.6 1.9 0.0 -0.3 1.0 0.9 1.3 1.3 1.0 0.9 0.8 0.7 1.2 1.3 1.4 0.7 0.8 1.5
High blood pressure 2.4 6.6 15.9 3.2 2.6 2.4 3.8 0.0 2.7 2.7 1.8 -3.2 3.1 2.0 2.3 4.0 2.4 2.8 0.0 1.8 3.1 3.7 2.5 3.5 2.9 3.4 0.7 1.6 2.6 3.4 1.6 0.8 -0.3 1.0
Hayfever, allergic rhinitis or eczema 1.3 2.8 6.6 2.0 2.2 0.3 1.6 0.0 1.9 1.9 1.9 -2.1 2.0 2.4 0.6 2.2 1.8 1.9 0.0 2.5 2.2 2.3 1.6 1.8 0.7 2.6 0.9 0.8 0.9 1.5 0.7 0.6 1.3 1.6
Multivitamins +/- minerals 0.4 0.6 2.5 -0.6 0.6 -0.7 -1.6 0.0 -0.4 -0.5 -0.2 0.3 -0.2 0.6 -0.3 0.5 -0.2 -0.4 0.0 0.6 0.2 -0.2 -0.2 -0.5 -1.5 0.8 -0.9 -1.6 -1.3 -0.7 -1.1 -1.3 -0.2 -0.5
Stomach or abdominal pain in last month 0.2 0.2 1.5 0.2 -0.0 -0.8 -0.7 0.0 -0.1 -0.0 1.2 0.1 -0.1 0.3 1.1 -0.2 -0.1 0.1 0.0 0.1 0.0 0.0 -0.3 -0.3 -0.3 -0.2 -0.1 0.1 -0.2 -0.2 0.0 -0.6 1.0 0.7
Supplements: Glucosamine 0.3 0.4 1.9 0.3 1.2 0.0 -0.1 0.0 0.4 0.3 0.9 -0.5 0.5 1.4 -0.7 0.9 0.3 0.4 0.0 1.3 0.9 0.8 0.5 0.8 0.8 0.7 -0.2 0.2 0.6 0.7 -0.0 -0.0 -1.0 -0.5
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 3.1 1.2 1.0 0.6 1.2 0.0 0.9 0.8 1.3 -0.8 0.8 0.7 0.4 -0.1 0.9 0.9 0.0 1.0 0.9 0.1 0.7 0.6 1.4 -0.5 1.4 1.8 1.5 1.1 1.6 1.4 1.1 1.1
Medication: Atenolol 1.2 1.5 3.5 1.6 1.3 -0.3 0.6 0.0 1.2 1.2 1.4 -1.3 1.4 1.3 1.9 1.2 1.2 1.2 0.0 1.2 1.5 1.2 1.3 1.3 1.1 0.9 1.5 1.3 1.3 1.4 1.4 1.1 1.2 1.4
Medication: Levothyroxine sodium 1.4 2.4 6.0 -1.5 -1.9 -1.7 -0.9 0.0 -1.8 -1.6 -1.5 1.9 -2.0 -1.4 -2.4 -1.9 -1.3 -1.9 0.0 -1.5 -1.7 -1.5 -1.3 -2.0 -2.2 -0.6 -0.5 -1.5 -2.1 -2.1 -1.3 0.2 -0.3 -1.0
Sitting height 3.2 22.7 34.7 -5.6 -5.6 -4.3 -4.9 0.0 -5.2 -5.2 -3.8 5.3 -5.3 -4.8 -4.4 -4.6 -4.8 -5.3 0.0 -4.7 -5.4 -4.8 -4.8 -5.5 -5.3 -3.1 -4.7 -5.1 -5.6 -5.9 -5.0 -3.8 -4.1 -4.5
Chronic bronchitis/emphysema (father) 3.3 3.9 7.7 -2.3 -1.9 -1.8 -1.8 0.0 -2.3 -2.3 -1.4 2.4 -2.3 -1.9 -1.6 -2.4 -2.2 -2.3 0.0 -1.8 -2.2 -2.8 -2.1 -2.4 -1.9 -2.2 -1.5 -2.0 -1.9 -2.2 -1.5 -1.4 -1.5 -2.1
High blood pressure (mother) 0.2 0.3 2.1 0.3 0.0 0.6 -0.7 0.0 0.4 0.4 0.6 -0.3 0.2 0.0 1.3 -0.2 0.3 0.5 0.0 -0.4 -0.1 0.3 0.2 0.8 1.5 -0.7 -0.0 0.8 1.1 0.6 0.3 0.4 -0.8 -0.2
Body mass index (BMI) 3.4 14.5 23.8 -4.2 -4.4 -4.0 -2.6 0.0 -4.7 -4.6 -3.6 4.9 -4.6 -3.7 -2.8 -4.7 -4.4 -4.7 0.0 -3.8 -4.4 -4.8 -4.3 -4.6 -2.8 -4.7 -2.8 -2.5 -3.0 -4.1 -2.8 -2.3 -3.0 -3.8
Impedance of leg (left) 0.3 1.5 5.9 0.5 1.8 1.3 1.2 0.0 1.2 1.2 0.5 -1.2 1.0 2.2 -0.8 0.8 1.2 1.2 0.0 2.3 1.5 1.0 1.1 1.1 -0.1 1.4 1.6 0.1 0.3 1.0 0.7 0.8 2.4 1.9
Leg predicted mass (left) 4.3 22.5 34.2 -5.1 -5.8 -5.4 -4.3 0.0 -5.4 -5.4 -3.3 5.6 -5.5 -5.5 -3.5 -5.2 -4.9 -5.5 0.0 -5.3 -5.7 -5.4 -4.9 -5.8 -4.7 -4.4 -4.1 -3.9 -4.8 -5.8 -4.1 -3.3 -3.5 -4.2
Trunk fat mass 6.3 26.9 41.9 -6.1 -5.7 -5.5 -4.0 0.0 -6.2 -6.2 -4.7 6.5 -6.3 -4.6 -4.8 -6.2 -5.8 -6.3 0.0 -4.5 -5.8 -6.3 -5.8 -6.4 -5.0 -5.3 -3.9 -4.3 -5.2 -6.1 -4.3 -3.5 -3.3 -4.6
Waist circumference 1.4 5.1 8.1 -2.3 -2.5 -2.5 -1.6 0.0 -2.9 -2.8 -2.1 2.8 -2.6 -2.1 -2.2 -2.0 -2.6 -2.8 0.0 -2.3 -2.5 -2.3 -2.5 -2.6 -1.9 -1.9 -2.0 -1.8 -2.1 -2.4 -2.0 -1.8 -2.3 -2.6
Number of incorrect matches in round 0.2 0.4 1.5 0.6 -0.5 1.1 1.1 0.0 0.4 0.3 -0.3 -0.6 0.4 -1.2 -0.3 0.6 0.1 0.5 0.0 -1.1 -0.0 0.3 0.0 0.5 0.9 0.2 -0.5 0.0 0.6 0.7 0.1 -0.2 -1.0 -0.6
Past tobacco smoking 0.4 0.7 3.2 -0.7 -0.7 1.1 -0.2 0.0 -0.3 -0.3 -1.8 0.1 -0.2 -0.3 -1.6 0.5 -0.6 -0.3 0.0 -0.1 -0.5 0.7 -0.4 0.1 -1.0 1.2 -0.9 -1.3 -1.0 -0.5 -1.4 -1.0 -0.7 -0.7
Alcohol usually taken with meals 0.4 0.6 2.3 -0.8 -0.4 -0.1 -0.4 0.0 -0.8 -0.8 -0.6 0.7 -0.7 -0.3 0.3 -0.1 -0.6 -0.8 0.0 -0.3 -0.5 -0.1 -0.6 -0.6 -1.5 0.6 -1.0 -1.4 -1.5 -1.0 -1.5 -1.4 -0.6 -0.7
Nervous feelings 1.5 2.8 4.4 1.7 1.9 2.0 1.6 0.0 1.7 1.7 1.7 -1.6 1.6 1.9 1.1 1.3 1.7 1.7 0.0 1.9 1.9 1.6 1.7 1.8 2.0 0.8 1.9 2.1 2.0 2.0 1.9 1.6 1.7 1.6
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 6.7 1.4 0.7 0.3 0.1 0.0 1.1 1.2 2.6 -1.0 1.0 0.9 0.6 1.0 1.3 1.0 0.0 0.7 1.0 1.3 1.2 1.3 1.0 1.0 1.5 1.4 1.1 1.1 1.1 1.6 1.2 1.3
Hearing difficulty/problems with background noise 1.3 2.1 4.1 1.7 1.9 0.7 1.8 0.0 1.7 1.7 1.1 -1.8 1.7 1.6 0.7 1.8 1.5 1.7 0.0 1.7 2.0 1.5 1.8 1.5 1.2 1.6 1.1 0.8 1.2 1.7 1.3 1.1 0.7 1.2
Hair/balding pattern: Pattern 2 0.4 0.5 3.6 0.0 0.3 -0.0 0.5 0.0 -0.4 -0.4 -0.1 0.4 -0.4 0.9 -0.5 -0.9 -0.6 -0.3 0.0 0.6 0.1 -0.8 -0.5 -0.0 1.2 -1.9 0.8 1.3 1.2 0.6 0.9 0.2 0.5 0.2
Had menopause 0.5 0.6 3.4 0.6 1.3 -0.1 0.5 0.0 0.2 0.2 0.2 -0.2 0.4 1.8 0.5 0.3 0.4 0.2 0.0 1.5 1.1 0.4 0.5 0.6 1.2 -0.2 1.1 1.3 1.2 0.9 1.0 1.1 -0.1 0.0
Had other major operations 3.1 3.8 8.2 2.4 2.3 1.7 1.2 0.0 2.1 2.1 1.9 -2.2 2.1 2.1 0.9 1.9 2.1 2.1 0.0 1.7 2.2 2.0 1.9 2.6 2.9 1.1 1.8 2.2 2.7 2.7 2.0 1.8 0.6 1.1
Forced vital capacity (FVC) 1.1 4.3 13.6 -2.4 -2.1 -1.8 -3.2 0.0 -1.7 -1.7 -1.1 1.9 -1.9 -2.5 -3.3 -1.7 -1.2 -1.8 0.0 -2.2 -2.2 -1.6 -1.6 -2.4 -3.7 -0.1 -1.3 -2.8 -3.4 -2.9 -2.3 -1.4 0.3 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 3.8 1.3 0.9 0.6 0.4 0.0 1.3 1.3 1.2 -1.1 1.1 0.1 2.0 0.2 1.2 1.4 0.0 0.3 0.9 0.1 1.2 0.5 1.4 -0.7 1.0 1.8 1.5 0.9 1.9 1.0 1.1 1.7
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 4.8 1.3 0.6 -0.0 0.5 0.0 0.3 0.3 2.2 -0.1 0.3 0.6 1.1 -0.2 0.5 0.3 0.0 0.0 0.7 -0.5 0.6 0.2 1.7 -1.4 1.4 1.9 1.7 1.0 1.7 1.4 0.7 0.7
Qualifications: None of the above 0.6 1.2 7.2 -0.6 -1.4 -1.2 0.5 0.0 -1.0 -1.0 -2.7 1.3 -1.4 -0.7 -0.2 -2.0 -0.5 -1.2 0.0 -1.7 -1.3 -1.5 -1.0 -0.9 -0.2 -1.6 0.4 -0.5 -0.4 -0.8 -0.3 1.2 -0.4 -1.2
Financial difficulties in last 2 years 0.5 0.7 3.5 -0.7 -0.7 -1.0 -1.1 0.0 -0.9 -0.9 -0.6 1.1 -1.0 -0.5 -1.5 -1.4 -0.6 -0.9 0.0 -0.7 -0.8 -1.4 -0.7 -1.1 -0.1 -1.9 0.2 0.4 -0.1 -0.7 0.2 -0.0 0.2 -0.1
Mouth/teeth dental problems 0.2 0.3 1.7 0.6 0.5 -0.3 0.0 0.0 0.5 0.5 1.3 -0.7 0.7 0.0 0.3 1.2 0.4 0.5 0.0 0.0 0.5 0.9 0.5 0.6 0.2 1.1 -0.1 0.1 0.2 0.6 0.0 -0.3 -0.4 0.2
Heart attack 0.1 0.1 0.4 0.2 -0.1 -0.3 0.1 0.0 0.3 0.3 0.6 -0.2 0.1 0.3 -0.1 0.3 0.6 0.2 0.0 -0.3 0.1 0.4 0.4 0.4 -0.1 0.5 0.5 -0.1 -0.1 0.1 -0.1 0.6 0.5 0.3
Allergy 0.3 0.7 2.8 -0.6 -1.0 0.2 -1.2 0.0 -0.7 -0.7 -0.8 0.8 -0.5 -1.4 1.0 -0.6 -1.0 -0.6 0.0 -1.5 -1.1 -1.2 -0.7 -0.5 0.5 -1.7 -0.6 -0.1 0.3 -0.1 0.1 -0.6 -1.3 -1.1
Pain all over the body in last month 0.3 0.3 2.3 -0.1 -0.4 -1.5 -0.5 0.0 -0.6 -0.5 0.2 0.5 -0.5 0.3 -0.5 -0.5 -0.5 -0.6 0.0 -0.1 -0.3 -0.4 -0.6 -0.4 -0.4 -0.1 -0.6 -0.7 -0.5 -0.5 -0.6 -0.2 -1.0 -0.9
Diabetes (self-reported) 0.6 0.9 4.8 1.1 1.0 0.2 0.0 0.0 0.7 0.8 2.2 -0.9 0.9 1.0 1.0 1.3 0.7 0.8 0.0 0.8 1.0 1.6 0.9 1.2 1.3 0.9 0.5 1.3 1.2 1.2 0.6 0.3 0.2 0.6
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 1.9 -0.1 -0.2 -1.0 0.0 0.0 0.1 0.0 1.0 0.0 -0.2 0.0 -1.4 0.0 0.5 -0.1 0.0 -0.4 -0.3 0.8 0.1 0.5 -0.5 0.8 0.5 -0.4 -0.4 -0.0 -0.7 0.2 1.1 0.3
Medication: Ramipril 0.9 1.2 5.2 1.0 0.6 2.3 1.1 0.0 0.9 0.9 0.8 -1.2 1.1 0.7 1.9 1.7 0.6 1.1 0.0 0.3 1.0 1.8 0.7 1.5 1.5 1.1 -0.3 1.1 1.3 1.4 0.3 -0.6 -0.1 0.4
Medication: Simvastatin 0.1 0.1 0.4 -0.5 -0.4 -0.2 0.2 0.0 -0.4 -0.5 -0.5 0.3 -0.4 -0.3 0.7 -0.0 -0.5 -0.4 0.0 -0.5 -0.3 -0.0 -0.4 -0.0 0.2 -0.3 -0.3 -0.1 0.1 0.1 -0.2 -0.6 -0.6 -0.4
Fluid intelligence score 2.0 4.2 9.3 2.4 3.1 1.8 0.9 0.0 2.4 2.3 2.4 -2.5 2.5 2.6 1.2 2.8 2.3 2.4 0.0 2.9 2.7 2.5 2.4 2.2 1.5 2.5 1.0 1.3 1.6 2.1 1.4 0.8 0.9 1.6
Illnesses of siblings 0.1 0.2 1.7 0.1 0.7 -0.1 0.0 0.0 0.2 0.1 0.7 -0.1 0.1 0.7 0.2 -0.0 0.3 0.1 0.0 0.8 0.5 0.1 0.4 0.0 0.1 -0.0 0.8 0.5 0.2 0.3 0.4 0.4 1.3 0.7
Neuroticism score 0.4 0.9 4.5 0.5 0.5 0.1 -0.6 0.0 0.3 0.3 1.6 -0.0 0.2 0.7 0.5 -0.6 0.3 0.4 0.0 0.6 0.4 -0.2 0.3 0.5 1.9 -1.6 1.2 2.1 1.8 0.9 1.5 1.2 0.5 0.5
Weight 5.9 29.0 43.7 -6.0 -6.2 -6.0 -4.6 0.0 -6.4 -6.3 -4.2 6.6 -6.4 -5.4 -4.6 -6.2 -5.8 -6.4 0.0 -5.4 -6.2 -6.4 -5.9 -6.6 -5.0 -5.4 -4.3 -4.3 -5.3 -6.3 -4.5 -3.6 -4.0 -5.0
Impedance of arm (right) 0.2 1.1 5.3 0.1 1.3 1.1 0.8 0.0 0.7 0.7 0.0 -0.9 0.7 2.1 -0.1 0.9 0.6 0.7 0.0 2.3 1.2 1.3 0.6 1.1 -0.2 1.6 1.0 -0.2 -0.0 0.9 0.0 0.0 2.2 1.4
Arm fat percentage (right) 3.8 14.8 23.7 -4.5 -4.2 -4.2 -2.6 0.0 -4.8 -4.7 -4.1 4.9 -4.8 -3.2 -3.2 -4.7 -4.5 -4.8 0.0 -3.2 -4.3 -4.7 -4.5 -4.6 -3.4 -4.2 -2.7 -3.0 -3.5 -4.2 -3.1 -2.7 -2.4 -3.5
Trunk fat-free mass 2.4 13.6 21.6 -3.8 -4.6 -4.4 -3.8 0.0 -4.0 -4.0 -2.0 4.2 -4.1 -4.7 -2.7 -3.6 -3.5 -4.1 0.0 -4.5 -4.3 -4.0 -3.6 -4.5 -3.8 -2.9 -3.5 -3.2 -3.9 -4.6 -3.3 -2.6 -3.3 -3.4
Hip circumference 8.7 37.6 60.1 -7.1 -6.7 -6.2 -5.3 0.0 -7.5 -7.4 -5.2 7.8 -7.5 -5.7 -5.2 -7.3 -6.9 -7.5 0.0 -5.7 -7.0 -7.5 -6.8 -7.4 -5.4 -6.6 -4.7 -4.7 -5.7 -7.1 -5.0 -4.0 -4.5 -5.9
Time employed in main current job 1.4 1.6 6.4 0.7 1.2 0.9 1.1 0.0 1.3 1.3 0.2 -1.5 1.4 1.9 0.9 2.1 1.3 1.2 0.0 1.9 1.6 2.2 1.6 1.7 0.5 2.5 0.8 0.3 0.5 1.2 0.2 0.8 0.1 0.6
Alcohol intake versus 10 years previously 0.7 1.1 4.0 -0.9 -0.7 -2.0 -1.3 0.0 -1.0 -1.0 -0.4 1.1 -1.1 -0.3 -0.8 -1.5 -0.9 -0.9 0.0 -0.3 -0.9 -1.5 -1.2 -1.2 -0.8 -1.4 -1.2 -1.2 -0.9 -1.2 -0.9 -0.8 -1.3 -1.3
Father’s age at death 1.3 1.8 8.9 -0.9 -1.4 -0.8 -0.4 0.0 -1.6 -1.6 -1.2 1.9 -1.6 -1.5 -1.0 -2.4 -1.3 -1.7 0.0 -1.5 -1.5 -2.5 -1.2 -1.5 0.1 -3.0 0.4 0.4 0.1 -0.9 0.4 0.6 -0.3 -1.0
Worrier / anxious feelings 0.9 1.6 5.9 1.4 1.2 0.6 1.2 0.0 1.3 1.3 1.4 -1.2 1.2 1.2 1.8 0.5 1.1 1.4 0.0 1.5 1.4 0.5 0.9 1.3 2.4 -0.7 0.6 1.9 2.2 1.6 1.7 0.9 -0.2 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 4.4 -1.2 -1.0 -0.3 -2.1 0.0 -1.5 -1.4 -0.5 1.6 -1.5 -0.6 -0.6 -1.7 -1.3 -1.5 0.0 -0.5 -1.0 -1.5 -1.1 -1.6 -1.2 -1.4 0.0 -0.1 -1.0 -1.4 -0.3 -0.1 0.3 -0.2
Falls in the last year 0.7 0.9 4.8 0.6 0.2 0.3 0.2 0.0 0.6 0.6 1.0 -0.2 0.4 -0.5 1.3 -0.8 1.0 0.5 0.0 -0.1 0.0 -0.3 0.7 -0.0 0.7 -0.9 1.9 1.8 0.9 0.2 1.6 2.2 1.4 1.4
Hair/balding pattern: Pattern 3 4.1 6.2 11.2 -2.9 -3.4 -2.4 -3.1 0.0 -2.7 -2.7 -1.2 2.8 -2.8 -2.9 -0.2 -2.7 -2.6 -2.7 0.0 -3.1 -3.3 -2.2 -3.0 -2.1 -1.5 -2.2 -2.5 -2.1 -2.0 -2.4 -2.6 -2.0 -2.8 -3.2
Number of live births 0.4 0.6 1.9 -0.3 -0.8 -1.4 -1.1 0.0 -0.8 -0.7 1.2 0.8 -0.9 -0.6 -1.2 -1.2 -0.8 -0.8 0.0 -1.1 -0.8 -0.8 -0.9 -0.9 -0.4 -1.0 -0.0 0.2 -0.4 -0.7 -0.1 0.1 0.0 -0.0
Forced expiratory volume in 1-second (FEV1) 1.0 3.2 12.5 -2.2 -1.5 -1.3 -2.6 0.0 -1.4 -1.4 -1.1 1.5 -1.5 -1.8 -2.9 -1.1 -1.2 -1.5 0.0 -1.2 -1.7 -1.2 -1.3 -2.1 -3.5 0.3 -1.4 -2.7 -3.2 -2.6 -2.1 -1.6 0.2 -0.5
Pulse rate 0.6 1.1 3.2 -1.2 -0.5 -0.6 -1.3 0.0 -1.0 -1.0 -0.3 1.0 -1.0 0.0 -0.7 -0.7 -1.0 -1.0 0.0 -0.2 -0.5 -0.7 -1.1 -1.4 -1.8 -0.1 -1.6 -1.4 -1.7 -1.6 -1.5 -1.7 -0.4 -0.6
Happiness 1.3 1.6 4.0 1.4 1.1 1.4 0.7 0.0 1.4 1.4 2.0 -1.2 1.2 1.0 0.6 1.2 1.8 1.3 0.0 0.8 1.1 1.5 1.8 1.3 1.0 1.1 1.6 1.5 1.1 1.0 1.2 1.8 1.3 1.4
Noisy workplace 1.5 1.8 5.4 -1.7 -1.5 -1.5 -0.1 0.0 -1.7 -1.7 -1.4 1.9 -1.7 -0.9 -1.1 -2.0 -1.6 -1.7 0.0 -1.3 -1.6 -1.9 -1.5 -1.6 -0.5 -2.3 -0.6 -0.3 -0.6 -1.3 -0.6 -0.5 -1.0 -1.2
Qualifications: A levels/AS levels or equivalent 0.9 2.0 4.6 1.8 1.5 1.5 1.1 0.0 1.6 1.6 2.1 -1.8 1.7 0.8 2.1 1.8 1.3 1.7 0.0 1.0 1.6 1.5 1.3 1.5 1.4 1.2 0.7 1.3 1.5 1.8 1.3 0.2 1.1 1.5
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 2.3 -0.3 -0.8 -0.1 0.6 0.0 -0.7 -0.7 -1.1 0.4 -0.5 -0.6 -1.2 0.0 -0.9 -0.5 0.0 -0.5 -0.5 -0.2 -0.7 -0.6 -0.3 -0.2 -1.3 -0.3 -0.4 -0.4 -0.8 -1.5 -1.2 -0.8
Mouth/teeth dental problems: Dentures 0.1 0.2 1.7 0.2 -0.4 0.4 0.7 0.0 -0.3 -0.3 -1.3 0.2 -0.3 -0.4 0.3 -0.5 -0.2 -0.2 0.0 -0.6 -0.0 -0.4 -0.3 -0.2 0.3 -0.6 0.1 0.0 0.2 0.1 0.2 0.0 -0.2 -0.3
Asthma 1.5 3.0 6.9 -2.0 -1.7 -1.6 -0.5 0.0 -1.9 -1.9 -1.1 2.0 -2.3 -1.4 -2.4 -2.4 -1.4 -2.1 0.0 -1.3 -1.6 -1.9 -1.7 -2.4 -2.4 -1.0 -1.4 -1.6 -2.4 -2.6 -1.7 -0.7 -0.7 -1.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.8 -0.4 -0.6 -0.8 -0.4 0.0 -0.2 -0.1 0.6 0.5 -0.4 -1.3 -0.4 -1.5 -0.2 -0.2 0.0 -0.7 -0.7 -1.2 -0.2 -0.6 0.4 -1.7 1.1 0.9 0.5 -0.2 1.1 1.3 1.1 0.7
Medication: Cholesterol lowering 0.2 0.3 1.3 -0.3 -0.1 0.7 0.8 0.0 -0.2 -0.2 -0.6 0.1 -0.3 0.1 1.1 0.3 0.2 -0.3 0.0 0.0 0.2 0.3 0.2 -0.5 -1.1 0.8 -0.3 -0.7 -1.0 -0.6 -0.6 -0.3 0.3 0.3
Depression (self-reported) 1.7 2.0 4.0 1.9 1.4 1.8 0.9 0.0 1.6 1.6 1.6 -1.7 1.7 0.9 2.0 2.0 1.8 1.7 0.0 0.6 1.5 1.8 1.7 1.6 1.1 1.6 1.0 1.2 1.2 1.5 1.2 0.8 0.9 1.4
Medication: Lansoprazole 2.3 2.6 7.3 1.7 1.6 2.1 1.6 0.0 2.0 2.0 0.2 -2.0 1.9 0.8 2.7 1.3 1.9 2.1 0.0 1.0 1.6 1.5 1.9 1.7 1.7 1.1 1.3 1.5 1.7 1.7 1.8 1.5 0.9 1.5
Prospective memory result 1.6 2.0 6.2 -1.3 -1.5 -1.5 -0.4 0.0 -1.6 -1.6 -0.9 1.8 -1.8 -1.2 -1.2 -2.0 -1.5 -1.6 0.0 -1.0 -1.4 -2.5 -1.5 -2.1 -1.1 -2.3 -0.9 -0.8 -1.1 -1.6 -0.6 -0.7 -0.7 -0.9
Lung cancer (father) 0.2 0.2 2.5 0.2 -0.4 0.2 1.6 0.0 0.1 0.2 -0.9 -0.1 -0.0 -0.9 -0.2 -0.8 -0.1 0.1 0.0 -0.9 -0.3 -0.6 -0.4 -0.4 -0.2 -0.4 -0.3 -0.2 -0.3 -0.5 0.0 0.3 -0.5 -0.0
Illnesses of mother 0.5 0.6 3.3 0.6 0.9 1.2 1.8 0.0 0.8 0.8 0.2 -0.8 0.9 0.5 -0.3 0.9 0.6 0.8 0.0 0.8 0.8 0.8 0.7 0.5 0.2 0.8 0.6 0.6 0.4 0.6 0.6 0.0 1.3 1.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.4 8.5 -1.9 -1.4 -1.5 -2.7 0.0 -1.3 -1.2 -0.5 1.2 -1.2 -1.7 -2.1 -0.7 -1.1 -1.3 0.0 -1.1 -1.5 -0.7 -1.2 -1.6 -2.9 0.4 -1.3 -2.2 -2.6 -2.1 -1.9 -1.7 0.1 -0.5
Pulse wave Arterial Stiffness index 1.5 1.8 4.3 1.3 1.9 1.0 1.7 0.0 1.3 1.4 1.9 -1.4 1.3 2.0 1.7 1.2 1.4 1.3 0.0 2.1 1.9 1.4 1.3 1.1 0.6 1.5 1.0 0.9 0.7 1.0 0.8 0.9 1.1 1.3
Impedance of arm (left) 0.2 0.9 5.1 -0.0 1.4 0.8 0.5 0.0 0.6 0.6 0.2 -0.6 0.5 2.1 -0.7 0.7 0.5 0.5 0.0 2.3 1.1 1.1 0.6 0.9 -0.2 1.3 0.9 -0.2 -0.0 0.7 0.0 0.1 2.0 1.1
Arm fat mass (right) 4.8 20.0 31.5 -5.1 -5.1 -4.8 -3.3 0.0 -5.4 -5.4 -4.3 5.6 -5.4 -4.2 -3.6 -5.4 -5.1 -5.4 0.0 -4.2 -5.1 -5.5 -5.1 -5.4 -3.9 -4.9 -3.3 -3.4 -4.1 -5.0 -3.6 -3.0 -3.0 -4.1
Trunk predicted mass 2.4 13.8 21.5 -3.8 -4.6 -4.5 -3.9 0.0 -4.0 -4.0 -2.0 4.2 -4.1 -4.6 -2.8 -3.7 -3.6 -4.1 0.0 -4.5 -4.4 -4.1 -3.6 -4.6 -3.8 -3.0 -3.5 -3.3 -4.0 -4.6 -3.3 -2.5 -3.2 -3.5
Standing height 1.5 15.3 27.1 -4.5 -4.5 -4.6 -4.3 0.0 -4.2 -4.1 -2.0 4.3 -4.4 -4.1 -4.1 -3.7 -3.6 -4.4 0.0 -3.9 -4.4 -3.9 -3.7 -4.8 -5.2 -2.1 -3.4 -4.3 -5.2 -5.2 -4.1 -2.8 -2.1 -2.9
Length of working week for main job 0.8 0.9 2.8 -0.5 -1.0 -1.2 -0.0 0.0 -0.9 -1.0 -0.7 0.9 -1.1 -1.0 0.0 -1.2 -0.8 -0.9 0.0 -1.7 -0.9 -1.4 -1.1 -0.8 -0.5 -1.3 -0.9 -1.2 -0.6 -0.8 -0.7 -0.8 -1.2 -1.3
Exposure to tobacco smoke at home 0.2 0.2 1.1 0.1 -0.2 -0.6 0.0 0.0 -0.1 -0.2 1.0 0.3 -0.2 -0.1 -0.3 -0.2 0.2 -0.2 0.0 -0.2 -0.2 -0.3 -0.0 -0.6 -1.1 0.2 -0.4 -0.6 -0.9 -0.9 -0.6 -0.2 -0.0 -0.0
Breastfed as a baby 0.1 0.1 0.7 -0.1 0.1 -0.2 -0.1 0.0 0.3 0.4 -0.0 -0.4 0.4 -0.1 -0.1 0.5 0.2 0.3 0.0 0.3 0.1 0.5 0.5 0.2 -0.5 0.8 0.3 -0.1 -0.3 0.0 0.1 0.1 0.8 0.8
Tense / ‘highly strung’ 2.6 4.3 8.6 2.3 1.9 1.6 0.6 0.0 1.9 2.0 2.9 -1.8 2.0 2.1 2.3 1.7 2.2 1.9 0.0 1.3 2.1 1.7 2.2 2.2 2.7 0.6 2.8 2.9 2.8 2.6 2.6 2.6 2.0 2.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 1.0 3.2 1.2 1.8 1.6 -0.2 0.0 0.7 0.7 1.2 -0.6 0.8 1.8 0.4 0.7 0.8 0.7 0.0 1.7 1.5 0.6 0.8 0.7 0.8 0.3 0.9 1.1 1.0 0.9 1.1 0.7 0.9 0.9
Hair/balding pattern: Pattern 4 0.3 0.7 3.1 0.7 1.1 0.8 0.6 0.0 0.6 0.7 0.1 -0.7 0.8 1.4 -0.8 1.3 0.7 0.5 0.0 1.4 0.9 1.5 1.0 0.9 0.0 1.8 0.6 0.3 0.1 0.5 0.1 0.7 0.0 0.4
Birth weight of first child 0.7 1.3 5.7 0.5 1.6 1.3 0.6 0.0 0.5 0.6 1.6 -0.4 0.5 2.4 0.4 0.4 0.8 0.4 0.0 1.8 1.4 0.8 1.0 0.8 0.9 0.3 1.7 1.6 1.0 0.9 1.1 1.5 1.7 1.2
Peak expiratory flow (PEF) 0.4 0.9 6.7 -1.0 -0.3 0.5 -1.2 0.0 -0.5 -0.5 -0.1 0.5 -0.5 -0.9 -2.6 -0.4 -0.5 -0.5 0.0 -0.4 -0.6 -0.5 -0.5 -1.2 -1.9 0.2 -0.7 -1.1 -1.6 -1.4 -0.8 -1.0 0.3 0.2
Pulse wave reflection index 3.2 3.9 7.9 2.4 1.9 1.9 2.8 0.0 2.1 2.1 2.1 -2.1 2.0 1.5 1.8 1.6 2.3 2.1 0.0 1.1 2.1 1.8 2.0 2.3 2.4 1.1 2.2 2.3 2.4 2.4 2.1 2.1 1.5 1.8
Ever highly irritable/argumentative for 2 days 0.2 0.3 2.7 0.4 0.0 0.1 1.0 0.0 0.4 0.4 0.2 -0.4 0.4 -0.7 1.6 0.3 0.3 0.4 0.0 -0.4 0.4 0.1 0.4 -0.4 -0.7 0.6 -0.2 -0.2 -0.5 -0.3 0.1 -0.4 0.7 1.0
Loud music exposure frequency 1.3 1.4 5.5 1.1 1.3 2.3 2.0 0.0 1.2 1.3 0.2 -1.3 1.2 1.3 1.1 0.7 0.8 1.4 0.0 1.4 1.2 0.8 0.9 1.2 1.4 0.2 0.9 1.1 1.4 1.4 1.2 0.6 0.8 1.2
Qualifications: O levels/GCSEs or equivalent 0.8 1.3 5.2 0.9 1.9 1.9 1.2 0.0 1.0 1.0 0.9 -1.1 1.3 1.6 0.9 1.1 0.5 1.2 0.0 2.3 1.6 0.7 1.0 0.6 1.1 0.3 0.4 1.5 1.2 1.0 1.3 0.2 0.2 1.1
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.4 0.5 0.6 0.9 0.9 0.0 0.6 0.6 -0.3 -0.6 0.6 0.3 -1.2 0.8 0.5 0.5 0.0 0.3 0.4 0.6 0.6 0.4 -0.0 0.8 0.5 0.2 0.1 0.4 0.3 0.4 0.6 0.7
Blood clot in the leg (DVT) 0.2 0.3 2.9 -0.1 0.0 -0.8 0.4 0.0 0.3 0.3 -0.3 -0.1 0.0 0.4 -1.7 -0.4 0.6 0.1 0.0 0.6 0.3 -0.1 0.7 0.2 0.3 -0.1 0.7 0.3 0.2 -0.0 0.4 1.7 -0.1 -0.1
Medication: Paracetamol 0.2 0.3 3.2 0.3 0.2 1.8 1.0 0.0 -0.1 -0.1 0.4 0.1 -0.2 0.4 1.5 -0.1 0.1 -0.1 0.0 -0.1 0.1 0.4 -0.1 -0.0 -0.3 0.2 0.4 0.4 -0.1 -0.0 -0.1 -0.4 1.4 0.8
Headache pain in last month 0.1 0.3 1.0 -0.6 -0.4 -0.6 -1.0 0.0 -0.5 -0.5 -0.3 0.5 -0.5 -0.5 -0.7 -0.5 -0.5 -0.5 0.0 -0.2 -0.6 -0.4 -0.5 -0.5 -0.6 -0.1 -0.4 -0.5 -0.6 -0.6 -0.6 -0.4 -0.3 -0.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 3.1 -0.2 -0.1 -1.4 -0.9 0.0 -0.3 -0.2 -0.1 0.5 -0.3 -0.0 -1.5 -1.3 -0.3 -0.2 0.0 0.1 -0.6 -1.2 -0.4 -0.4 0.6 -1.8 0.7 0.7 0.6 -0.2 0.7 0.9 -0.2 -0.2
Glaucoma (self-reported) 1.3 1.6 3.8 1.6 1.4 1.3 1.0 0.0 1.5 1.4 1.9 -1.3 1.4 1.0 1.3 0.8 1.5 1.5 0.0 1.4 1.6 0.7 1.4 0.7 0.7 0.6 1.1 1.3 0.9 0.9 1.5 0.9 1.5 1.9
Gout (self-reported) 2.4 3.3 6.5 2.2 1.9 1.8 2.2 0.0 1.9 2.0 1.4 -2.0 2.0 1.4 2.5 2.1 2.1 1.9 0.0 1.3 2.1 2.1 2.0 1.6 1.0 2.1 1.6 1.6 1.3 1.7 1.6 1.5 2.1 2.2
Hypothyroidism/myxoedema (self-reported) 5.2 10.1 16.0 -3.6 -3.8 -3.4 -1.7 0.0 -3.6 -3.5 -3.7 3.8 -4.0 -3.4 -3.1 -3.9 -3.2 -3.8 0.0 -3.3 -3.7 -3.6 -3.2 -3.9 -3.6 -2.3 -1.9 -3.0 -3.7 -3.9 -2.8 -1.3 -1.2 -2.3
Medication: Amlodipine 5.9 8.3 13.2 3.1 3.6 2.4 3.0 0.0 3.3 3.3 1.9 -3.3 3.3 3.1 2.1 2.8 2.8 3.4 0.0 3.6 3.4 3.1 2.9 3.3 3.1 2.2 2.4 2.9 3.2 3.4 3.0 2.3 2.3 2.9
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.8 0.1 -0.3 0.3 0.8 0.0 -0.0 -0.0 -0.1 -0.0 -0.1 -0.1 -0.3 -0.1 0.2 -0.0 0.0 -0.3 0.1 0.1 -0.2 -0.4 -0.9 0.5 -0.4 -0.5 -0.8 -0.6 -0.5 -0.6 0.7 0.4
Birth weight 0.3 0.6 1.8 0.5 1.1 0.3 1.0 0.0 1.1 1.0 0.7 -0.8 0.8 0.8 0.3 0.1 1.2 1.0 0.0 1.0 0.8 0.0 1.1 0.4 0.6 -0.0 0.9 0.7 0.7 0.4 1.2 1.3 0.2 0.8
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.5 -0.4 -0.7 -1.0 0.4 0.0 -0.8 -0.8 -0.8 1.0 -1.0 -0.1 -0.9 -1.2 -0.3 -1.0 0.0 -0.3 -0.4 -0.9 -0.4 -0.6 -0.0 -1.0 0.3 0.0 -0.2 -0.6 -0.1 1.1 -0.5 -0.9
High blood pressure (siblings) 0.3 0.5 2.1 0.9 -0.0 1.2 0.6 0.0 0.6 0.6 0.2 -0.7 0.8 -0.0 0.2 0.8 0.2 0.8 0.0 -0.2 0.3 0.5 0.2 0.9 1.5 -0.2 0.1 1.0 1.4 1.1 0.9 -0.0 -0.6 0.2
Forced vital capacity (FVC), Best measure 0.6 2.3 8.8 -1.7 -1.4 -1.5 -3.0 0.0 -1.2 -1.2 -0.3 1.3 -1.2 -1.8 -2.1 -0.9 -0.8 -1.3 0.0 -1.5 -1.6 -0.7 -1.1 -1.5 -2.9 0.4 -0.9 -2.1 -2.6 -2.1 -1.8 -1.2 0.5 -0.3
Body fat percentage 5.2 20.7 33.1 -5.4 -4.9 -4.9 -3.0 0.0 -5.6 -5.6 -4.5 5.7 -5.6 -3.7 -4.4 -5.5 -5.3 -5.7 0.0 -3.7 -5.0 -5.6 -5.2 -5.5 -4.2 -4.8 -3.2 -3.7 -4.4 -5.1 -3.7 -3.0 -2.9 -4.1
Leg fat percentage (right) 4.1 14.8 25.7 -4.4 -4.1 -3.9 -2.1 0.0 -4.7 -4.7 -3.8 4.9 -4.8 -3.4 -3.6 -5.0 -4.4 -4.7 0.0 -3.3 -4.2 -5.1 -4.4 -4.8 -3.4 -4.5 -2.6 -2.8 -3.5 -4.4 -2.8 -2.3 -2.4 -3.4
Arm fat-free mass (right) 3.6 18.4 28.5 -4.5 -5.1 -5.1 -4.1 0.0 -4.7 -4.7 -2.6 4.9 -4.8 -5.1 -3.6 -4.6 -4.3 -4.8 0.0 -5.0 -5.0 -5.0 -4.3 -5.3 -4.3 -3.9 -3.8 -3.7 -4.4 -5.3 -3.6 -2.9 -3.5 -3.9
Exposure to tobacco smoke outside home 0.4 0.5 2.0 -0.7 -0.7 -0.1 -0.8 0.0 -0.7 -0.7 -0.6 0.9 -0.9 0.0 -0.9 -1.4 -0.5 -0.7 0.0 -0.1 -0.5 -1.3 -0.5 -0.8 -0.5 -1.4 0.6 -0.1 -0.4 -0.7 0.1 0.2 0.8 0.1
Comparative body size at age 10 0.1 0.4 1.8 0.6 -0.1 0.6 1.1 0.0 0.4 0.4 -0.6 -0.6 0.6 -0.5 1.4 1.1 0.1 0.5 0.0 -0.3 0.1 0.9 0.1 0.4 -0.0 0.9 -1.0 -0.3 -0.1 0.2 -0.4 -1.0 -0.9 -0.2
Number of full brothers 0.6 0.8 2.7 -1.1 -0.6 -0.1 -0.6 0.0 -1.0 -0.9 -0.5 1.1 -1.0 0.2 -0.9 -0.6 -1.2 -1.0 0.0 0.4 -1.0 -0.0 -0.9 -0.8 -0.6 -0.3 -1.5 -0.3 -0.8 -1.2 -1.3 -0.9 -1.7 -1.2
Worry too long after embarrassment 3.2 5.4 8.0 2.8 2.1 0.9 1.9 0.0 2.8 2.8 2.5 -2.7 2.6 1.4 2.4 2.0 2.7 2.7 0.0 1.6 2.5 2.0 2.7 2.5 2.5 1.4 2.6 2.6 2.7 2.7 2.8 2.6 2.1 2.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 3.7 0.9 1.5 0.3 0.1 0.0 0.7 0.7 1.1 -0.9 1.0 1.9 1.9 1.5 0.7 0.8 0.0 1.5 1.4 1.4 0.7 1.5 1.0 1.1 0.6 0.6 1.0 1.3 0.5 -0.1 0.2 0.2
Wheeze or whistling in the chest in last year 0.8 1.4 2.5 -1.1 -1.5 -0.9 0.6 0.0 -1.3 -1.3 -1.5 1.3 -1.4 -1.0 -1.6 -1.2 -1.0 -1.5 0.0 -1.3 -1.2 -1.4 -1.1 -1.5 -1.5 -0.7 -0.9 -1.2 -1.5 -1.5 -1.1 -0.5 -1.0 -1.1
Number of children fathered 0.7 0.8 2.0 -0.8 -0.8 -1.3 -0.3 0.0 -1.1 -1.1 -0.8 1.2 -1.1 -0.3 -0.3 -1.1 -0.6 -1.2 0.0 -0.5 -0.9 -1.3 -0.9 -1.0 -0.5 -1.2 -0.7 -0.8 -0.7 -1.0 -0.9 -0.3 -1.2 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.8 5.1 1.6 1.4 1.2 1.3 0.0 1.4 1.4 2.3 -1.5 1.5 1.3 1.9 1.7 1.4 1.4 0.0 1.2 1.6 1.6 1.5 1.5 1.2 1.5 0.8 1.1 1.2 1.4 1.0 0.8 0.4 0.9
Age at first live birth 0.6 1.1 6.2 0.7 1.4 1.1 1.0 0.0 1.0 1.0 -0.2 -1.3 1.2 1.0 0.3 2.1 0.9 1.0 0.0 1.2 1.2 1.7 1.1 1.1 -0.3 2.5 -0.3 -0.7 -0.2 0.7 -0.4 -0.5 0.2 0.4
Pulse wave peak to peak time 2.0 2.4 5.0 -1.6 -2.2 -1.3 -2.0 0.0 -1.5 -1.6 -2.2 1.6 -1.5 -2.2 -2.1 -1.2 -1.5 -1.5 0.0 -2.2 -2.1 -1.6 -1.5 -1.3 -1.0 -1.4 -1.2 -1.3 -1.1 -1.2 -1.1 -1.1 -1.2 -1.5
Health satisfaction 0.3 0.3 1.6 0.0 -1.0 0.1 0.1 0.0 -0.4 -0.3 0.2 0.6 -0.7 -0.9 -0.7 -1.1 -0.2 -0.4 0.0 -1.2 -0.7 -0.5 -0.4 -0.6 -0.1 -0.8 0.5 0.7 -0.0 -0.5 0.2 0.7 0.7 0.5
Shortness of breath walking on level ground 0.8 1.0 3.2 -0.9 -1.6 -0.3 0.2 0.0 -0.7 -0.6 -1.7 0.9 -0.9 -1.4 -1.4 -1.1 -0.3 -0.8 0.0 -1.5 -1.2 -0.9 -0.4 -1.3 -1.8 -0.4 0.4 -0.8 -1.4 -1.4 -0.4 0.2 1.1 0.8
Qualifications: College or University degree 1.9 5.9 12.4 2.6 2.8 1.9 1.6 0.0 2.8 2.8 3.5 -2.9 2.9 2.2 2.6 2.9 2.5 2.9 0.0 2.3 2.7 2.9 2.6 2.9 2.9 2.0 1.2 2.5 2.8 2.8 2.0 1.2 0.8 1.8
Eye problems/disorders: None of the above 0.8 0.9 2.7 -1.1 -1.4 -1.6 -1.0 0.0 -0.6 -0.6 -0.2 0.4 -0.5 -1.7 -0.7 0.2 -0.7 -0.6 0.0 -1.6 -1.2 -0.1 -0.5 -0.5 -1.0 0.5 -1.3 -1.3 -1.1 -0.7 -1.3 -1.2 -1.3 -1.1
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.7 0.7 0.8 1.0 1.0 0.0 0.8 0.7 1.2 -0.9 0.9 0.8 0.8 1.1 0.5 0.8 0.0 0.8 0.6 1.1 0.7 1.2 1.3 0.6 -0.0 0.8 1.1 1.0 0.4 0.1 -1.1 -0.3
Emphysema/chronic bronchitis 0.5 0.5 3.6 -0.4 -1.4 -0.3 1.0 0.0 -0.5 -0.5 -1.1 0.4 -0.6 -1.6 -0.8 -0.6 -0.4 -0.5 0.0 -1.9 -0.9 -0.4 -0.7 -0.3 -0.4 -0.0 -0.3 -0.7 -0.5 -0.4 -0.5 -0.0 -0.5 -0.7
Medication for pain relief, constipation, heartburn 0.2 0.4 2.2 -0.4 0.0 -0.5 -1.1 0.0 -0.3 -0.4 -0.5 0.4 -0.2 0.2 -1.4 -0.4 -0.6 -0.3 0.0 0.6 -0.3 -0.9 -0.4 -0.4 0.2 -0.9 -0.8 -0.3 -0.0 -0.4 -0.2 -0.2 -1.5 -1.1
Neck or shoulder pain in last month 0.3 0.4 1.7 0.5 0.5 0.7 1.3 0.0 0.3 0.3 0.3 -0.5 0.5 0.9 1.1 0.6 -0.1 0.4 0.0 1.2 0.7 0.6 0.3 0.5 0.8 -0.0 0.1 0.9 0.8 0.7 0.5 -0.5 -0.0 0.5
Medication: Blood pressure 0.6 1.0 6.0 0.4 0.8 1.6 0.9 0.0 0.5 0.6 0.2 -0.9 0.7 0.9 2.0 1.9 0.3 0.6 0.0 1.1 1.0 2.1 0.6 1.1 0.1 2.5 -0.8 -0.2 -0.1 0.7 -0.7 -0.8 -0.3 -0.0
Angina (self-reported) 0.3 0.4 1.0 1.0 -0.1 0.2 0.3 0.0 0.6 0.7 0.5 -0.6 0.6 -0.1 1.0 0.6 1.0 0.6 0.0 -0.9 0.3 0.8 0.8 0.6 0.3 0.8 1.0 0.5 0.4 0.6 0.6 1.0 0.6 0.7
Migraine (self-reported) 0.3 0.4 2.2 -0.3 0.4 -0.2 -0.4 0.0 -0.4 -0.4 -0.4 0.4 -0.2 0.7 -1.0 0.3 -0.3 -0.5 0.0 0.9 0.1 0.5 -0.3 -0.4 -1.5 1.1 -0.1 -0.8 -1.2 -0.7 -0.9 -0.7 0.8 0.2
Medication: Ibuprofen 0.6 0.7 3.0 0.3 -0.2 -0.5 0.1 0.0 0.3 0.4 1.2 -0.0 0.1 -1.1 0.1 -0.9 0.5 0.3 0.0 -0.5 -0.1 -0.6 0.4 -0.1 0.7 -1.1 1.6 1.4 0.8 0.3 1.6 1.7 1.6 1.3
Medication: Allopurinol 1.9 2.5 6.6 1.6 1.6 1.3 1.9 0.0 1.7 1.7 1.4 -1.7 1.6 1.3 2.6 1.6 1.9 1.6 0.0 1.2 1.7 1.8 1.8 1.1 0.3 1.9 1.6 1.3 0.7 1.1 1.3 1.3 2.5 2.5
Medication: Omeprazole 1.4 1.7 5.1 -1.5 -1.8 -2.2 -0.5 0.0 -1.0 -0.9 -0.5 0.9 -1.2 -1.2 -1.2 -0.6 -0.5 -1.2 0.0 -1.7 -1.5 0.0 -0.9 -0.5 -1.9 1.0 -1.0 -2.3 -2.1 -1.5 -2.2 -0.3 -1.4 -1.6
Medication: Seretide 50 evohaler 0.1 0.1 1.2 0.0 0.1 -0.1 1.1 0.0 0.2 0.2 0.1 -0.3 0.1 -0.1 0.2 0.4 0.5 0.2 0.0 0.0 0.2 0.6 0.4 0.3 -0.2 0.7 -0.3 -0.3 -0.3 -0.1 -0.4 -0.1 -0.1 0.0
Mean time to correctly identify matches 1.9 3.6 6.2 2.1 2.1 2.5 1.6 0.0 2.2 2.2 0.7 -2.4 2.4 2.0 1.7 2.4 2.2 2.3 0.0 1.9 2.3 2.2 2.1 2.2 1.4 2.2 1.3 1.2 1.6 2.1 1.5 1.1 1.6 1.9
Heart disease (mother) 0.6 0.7 3.8 -0.4 -1.5 -1.0 -1.2 0.0 -0.8 -0.7 -0.3 0.7 -0.7 -1.4 0.8 -0.1 -0.8 -0.8 0.0 -2.0 -1.2 -0.5 -0.8 -0.6 -0.9 0.1 -0.5 -1.0 -0.8 -0.5 -0.7 -0.6 -0.5 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.7 3.2 7.9 1.9 1.9 1.5 0.9 0.0 2.0 2.1 2.8 -2.0 2.0 1.8 1.0 1.8 1.9 2.1 0.0 1.8 1.9 2.4 1.8 2.1 1.6 1.7 1.6 2.0 1.7 1.8 1.5 1.4 1.6 2.0
Whole body fat mass 6.2 25.7 40.1 -5.9 -5.7 -5.4 -3.7 0.0 -6.2 -6.1 -4.8 6.3 -6.2 -4.7 -4.4 -6.0 -5.8 -6.2 0.0 -4.5 -5.7 -6.2 -5.7 -6.2 -4.8 -5.2 -3.8 -4.1 -4.9 -5.9 -4.2 -3.4 -3.4 -4.6
Leg fat mass (right) 5.6 21.5 34.4 -5.2 -5.3 -5.0 -3.0 0.0 -5.6 -5.5 -4.3 5.8 -5.7 -4.6 -3.8 -5.7 -5.1 -5.6 0.0 -4.5 -5.3 -5.9 -5.1 -5.9 -4.3 -5.1 -3.4 -3.6 -4.4 -5.5 -3.6 -2.9 -3.1 -4.1
Arm predicted mass (right) 3.3 17.0 26.9 -4.3 -5.0 -5.0 -3.9 0.0 -4.5 -4.5 -2.5 4.8 -4.6 -5.0 -3.5 -4.5 -4.0 -4.6 0.0 -5.0 -4.9 -4.9 -4.1 -5.2 -4.1 -3.9 -3.5 -3.4 -4.2 -5.1 -3.3 -2.5 -3.3 -3.6
Pulse rate, automated reading 0.4 1.3 4.8 -1.2 -0.8 -0.2 -0.2 0.0 -0.9 -0.9 -1.4 0.6 -0.7 -0.4 -0.8 0.1 -1.1 -0.8 0.0 -0.7 -0.8 0.2 -1.0 -0.6 -1.7 0.9 -2.0 -1.8 -1.7 -1.2 -2.0 -2.2 -1.4 -1.3
Alcohol intake frequency. 0.1 0.2 1.1 -0.3 -0.4 -0.8 -0.3 0.0 -0.5 -0.5 -0.5 0.6 -0.6 0.4 0.8 -0.8 -0.3 -0.5 0.0 -0.0 -0.2 -0.6 -0.4 0.0 0.5 -1.1 0.2 0.1 0.3 -0.0 0.0 0.4 -0.4 -0.6
Comparative height size at age 10 1.7 9.5 24.0 -3.1 -3.7 -4.4 -2.5 0.0 -2.8 -2.8 -2.1 2.8 -2.9 -3.7 -2.5 -1.9 -2.4 -3.0 0.0 -3.6 -3.2 -2.5 -2.6 -3.3 -4.9 -0.0 -2.9 -4.8 -4.7 -3.9 -3.8 -2.6 -1.7 -2.4
Number of full sisters 0.4 0.5 2.7 0.3 -0.7 -0.0 -0.7 0.0 -0.1 -0.1 1.2 0.4 -0.4 -0.8 0.4 -1.3 -0.0 -0.1 0.0 -0.9 -0.5 -0.6 -0.4 -0.3 0.6 -1.6 0.9 1.3 0.7 -0.0 0.9 0.5 1.1 1.0
Suffer from ‘nerves’ 1.1 1.7 3.9 1.1 1.5 1.3 0.4 0.0 1.1 1.2 1.1 -1.2 1.1 1.7 0.5 1.0 0.9 1.2 0.0 2.0 1.5 1.1 1.2 1.4 1.5 0.5 1.9 1.7 1.6 1.7 1.7 1.5 1.7 1.6
Overall health rating 0.0 0.1 0.4 0.1 -0.5 0.5 0.3 0.0 -0.5 -0.4 -0.2 0.5 -0.5 0.4 0.3 -0.3 -0.2 -0.6 0.0 0.1 -0.0 0.2 -0.2 -0.0 0.1 -0.1 0.5 0.6 0.1 -0.0 0.0 0.4 0.2 -0.1
Chest pain or discomfort 0.2 0.3 1.7 0.5 0.8 0.3 0.3 0.0 -0.0 0.0 1.2 0.0 0.0 1.3 0.1 -0.0 0.2 -0.0 0.0 1.1 0.7 0.2 0.3 0.1 -0.1 0.1 0.9 0.6 0.1 0.1 0.5 0.3 1.3 1.0
Had major operations 2.8 3.3 5.2 1.9 1.6 2.0 2.3 0.0 2.1 2.1 0.8 -2.2 2.1 1.2 2.1 2.2 2.0 2.1 0.0 1.6 2.0 1.9 2.1 1.9 1.3 2.0 1.9 1.4 1.6 2.0 1.7 1.7 1.5 1.9
Age at last live birth 0.3 0.4 3.1 0.5 0.6 0.3 0.2 0.0 0.6 0.6 0.5 -0.7 0.6 0.3 -0.4 1.4 0.5 0.5 0.0 0.2 0.6 1.1 0.6 0.5 -0.5 1.8 -0.3 -0.5 -0.4 0.2 -0.4 -0.3 0.3 0.3
Family relationship satisfaction 1.0 1.2 5.7 1.5 0.7 -0.3 0.7 0.0 1.4 1.4 2.4 -1.2 1.1 0.5 0.3 0.8 1.4 1.3 0.0 0.4 0.9 0.9 1.2 0.9 0.4 0.8 1.4 0.8 0.7 0.9 1.1 1.0 1.9 1.9
Leg pain on walking 0.2 0.2 1.4 -0.3 -0.3 -0.2 0.9 0.0 -0.3 -0.3 -0.9 0.4 -0.4 -0.1 -1.2 -0.7 -0.1 -0.4 0.0 0.1 -0.2 -0.5 -0.0 -0.7 -0.4 -0.3 -0.3 -0.0 -0.5 -0.8 -0.1 0.4 -0.4 -0.1
Qualifications: NVQ or HND or HNC or equivalent 2.1 2.5 5.1 -1.8 -1.9 -1.6 -2.3 0.0 -1.6 -1.6 -0.0 1.6 -1.6 -2.1 -2.2 -1.9 -1.9 -1.4 0.0 -1.7 -1.9 -1.9 -1.9 -1.8 -1.5 -1.7 -1.4 -1.1 -1.4 -1.7 -1.2 -1.8 -0.6 -0.8
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.6 0.7 0.4 0.3 0.2 0.0 0.3 0.3 -0.6 -0.4 0.3 0.9 -1.3 0.3 0.1 0.4 0.0 0.6 0.3 0.3 0.0 0.7 1.1 -0.2 -0.1 0.5 0.9 0.7 0.4 0.2 -0.7 -0.3
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.6 -0.0 0.9 0.7 -0.3 0.0 0.1 0.1 -0.2 -0.1 0.2 1.3 0.6 0.6 0.3 0.0 0.0 0.9 0.8 0.3 0.4 0.3 -0.0 0.7 0.2 -0.3 -0.1 0.3 -0.1 0.3 0.3 -0.1
Medication: Aspirin 0.1 0.2 1.3 0.2 -0.6 0.1 0.4 0.0 0.1 0.1 0.4 -0.3 0.1 -0.5 0.3 0.7 0.4 0.1 0.0 -0.9 0.0 0.7 0.2 0.4 -0.4 1.1 -0.1 -0.5 -0.3 0.2 -0.4 -0.4 0.2 0.1
Supplements: Vitamin C 0.1 0.2 0.8 -0.7 0.0 -0.5 -0.4 0.0 -0.0 -0.0 -0.6 0.1 -0.0 -0.3 0.2 0.3 0.1 -0.1 0.0 0.1 -0.4 0.3 0.1 0.1 -0.8 0.7 0.3 -0.9 -0.7 -0.3 -0.5 0.1 0.4 -0.1
Knee pain experienced in last month 0.5 0.7 2.3 0.9 1.1 1.0 1.1 0.0 0.7 0.7 1.1 -0.8 0.8 0.4 1.5 0.2 0.5 0.9 0.0 0.9 1.2 0.4 0.3 0.3 1.0 -0.3 0.4 1.5 1.1 0.7 1.2 -0.0 0.8 1.2
Hypertension (Self-reported) 2.8 7.9 18.1 3.4 2.9 2.6 4.0 0.0 3.0 3.0 1.9 -3.5 3.4 2.5 2.3 4.3 2.6 3.1 0.0 2.1 3.4 4.0 2.8 3.9 3.2 3.5 0.9 1.8 3.0 3.8 1.8 1.1 -0.2 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 1.0 -0.1 -0.3 0.1 -0.1 0.0 0.3 0.3 -0.6 -0.2 0.1 -0.6 -0.1 -0.1 0.5 0.2 0.0 -0.6 -0.3 0.1 0.3 -0.0 -1.0 0.8 0.5 -0.8 -0.8 -0.4 -0.2 0.7 0.9 0.6
Illnesses of father: Heart disease 1.6 2.2 5.1 1.7 1.4 2.1 1.4 0.0 1.5 1.4 0.7 -1.7 1.7 1.3 1.2 2.2 1.3 1.6 0.0 1.1 1.6 2.0 1.5 1.9 1.8 1.4 1.0 1.5 1.8 2.1 1.3 0.3 0.5 1.2
Illnesses of siblings: Diabetes 0.7 0.9 2.1 1.3 1.2 1.0 0.9 0.0 1.0 1.0 1.5 -0.9 1.0 1.2 0.8 0.8 1.2 1.0 0.0 1.2 1.2 1.0 1.1 0.7 0.5 0.8 0.6 1.0 0.6 0.5 0.8 0.8 0.6 1.0
Smoking status: Previous 0.5 0.8 5.0 0.8 1.1 -0.3 0.4 0.0 0.7 0.7 1.9 -0.6 0.7 0.8 2.2 0.4 0.9 0.7 0.0 0.5 0.9 0.4 0.7 0.6 0.9 0.0 1.0 1.2 1.0 0.8 1.1 0.8 1.0 1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 6.9 -1.3 -1.0 -1.2 -1.3 0.0 -0.9 -0.9 -0.2 1.0 -1.1 -1.0 -2.6 -0.9 -0.9 -0.9 0.0 -0.7 -1.2 -0.9 -0.8 -1.1 -1.3 -0.7 -0.9 -0.9 -1.2 -1.3 -1.0 -1.0 -0.1 -0.3
Whole body fat-free mass 3.4 19.3 29.3 -4.7 -5.4 -5.1 -4.4 0.0 -4.9 -4.9 -2.7 5.1 -5.0 -5.3 -3.3 -4.6 -4.4 -5.0 0.0 -5.1 -5.2 -4.9 -4.5 -5.4 -4.4 -3.8 -4.0 -3.7 -4.6 -5.4 -3.9 -3.1 -3.5 -4.0
Leg fat-free mass (right) 4.0 21.3 32.7 -5.0 -5.6 -5.5 -4.4 0.0 -5.3 -5.2 -3.1 5.5 -5.3 -5.2 -3.2 -5.1 -4.8 -5.3 0.0 -5.0 -5.5 -5.4 -4.8 -5.7 -4.4 -4.5 -3.9 -3.7 -4.6 -5.6 -3.9 -3.1 -3.5 -4.1
Arm fat percentage (left) 3.9 15.7 25.4 -4.7 -4.2 -4.4 -2.8 0.0 -4.9 -4.9 -4.0 5.0 -4.9 -3.2 -3.5 -4.9 -4.7 -4.9 0.0 -3.2 -4.4 -4.8 -4.6 -4.7 -3.4 -4.5 -2.9 -3.0 -3.6 -4.4 -3.2 -2.7 -2.6 -3.7
Average weekly red wine intake 0.2 0.3 1.1 -0.3 0.1 -1.0 -0.7 0.0 -0.5 -0.6 1.1 0.6 -0.5 0.2 -0.0 -0.9 -0.4 -0.5 0.0 0.2 -0.2 -0.6 -0.5 -0.5 -0.0 -1.0 -0.2 0.2 -0.1 -0.4 -0.2 -0.6 0.4 -0.0
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.5 -0.5 0.3 0.3 -0.6 0.0 -0.4 -0.4 0.3 0.3 -0.3 0.7 0.2 0.2 -0.2 -0.4 0.0 0.7 0.0 0.0 -0.0 -0.4 -0.6 0.0 -0.0 -0.1 -0.4 -0.3 -0.4 -0.6 0.4 0.1
Mood swings 0.7 1.3 5.1 1.0 1.1 0.9 0.1 0.0 0.8 0.8 1.3 -0.6 0.6 0.9 1.5 -0.3 0.8 0.9 0.0 0.8 0.9 -0.0 0.8 0.8 2.2 -1.3 1.3 2.3 2.1 1.2 1.9 1.6 0.5 0.7
Loneliness, isolation 0.4 0.5 4.5 0.2 0.2 -0.9 -1.4 0.0 0.2 0.2 2.1 0.1 -0.0 0.2 0.4 -0.8 0.5 0.2 0.0 -0.0 0.0 -0.4 0.2 -0.0 0.6 -1.0 0.9 1.1 0.6 0.0 0.8 1.0 0.7 0.5
Long-standing illness, disability or infirmity 0.8 1.3 6.8 1.4 1.5 0.6 1.0 0.0 0.5 0.6 1.4 -0.7 0.7 2.6 1.4 1.4 0.9 0.5 0.0 2.0 1.6 1.7 1.0 1.2 0.8 1.5 0.7 1.0 0.8 1.0 0.4 0.7 0.1 0.3
Ever had bowel cancer screening 2.3 2.7 7.1 2.0 1.4 1.0 1.1 0.0 1.8 1.8 2.1 -1.9 2.0 1.2 0.5 2.4 1.8 1.7 0.0 0.9 1.5 2.5 1.9 2.3 1.1 2.7 1.7 1.0 1.2 1.9 1.2 1.6 1.1 1.3
Diabetes diagnosed by doctor 1.0 1.6 6.9 1.5 1.3 0.3 1.0 0.0 1.2 1.2 2.6 -1.3 1.3 1.2 1.4 1.5 1.2 1.2 0.0 1.1 1.4 1.8 1.4 1.3 1.4 1.0 0.8 1.8 1.4 1.4 1.1 0.6 0.8 1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.8 1.9 4.3 1.6 0.3 1.4 0.6 0.0 1.5 1.6 2.1 -1.5 1.5 -0.9 0.6 1.3 1.6 1.5 0.0 -1.1 0.6 1.4 1.4 1.4 1.3 1.1 1.8 1.5 1.5 1.6 1.7 1.5 1.9 1.7
Friendships satisfaction 0.3 0.4 0.8 0.8 0.2 -0.5 0.4 0.0 0.8 0.8 0.9 -0.7 0.5 0.2 -0.4 0.2 0.9 0.8 0.0 -0.1 0.3 0.4 0.6 0.7 0.6 0.1 0.8 0.3 0.6 0.7 0.6 0.8 0.7 0.7
Qualifications: nursing, teaching 0.8 1.2 4.1 0.9 1.7 0.3 0.2 0.0 0.9 0.9 2.0 -1.1 1.1 2.0 0.2 1.5 0.9 1.0 0.0 2.0 1.6 1.3 0.9 1.0 0.6 1.2 0.6 0.6 0.7 1.1 0.6 0.0 1.2 1.1
Commuting to job workplace: Walk 0.3 0.3 2.7 0.2 -0.2 1.1 1.1 0.0 0.5 0.5 -0.2 -0.5 0.5 -1.0 1.6 0.6 0.3 0.6 0.0 -0.6 -0.2 0.7 0.3 0.6 -0.1 0.8 -0.2 -0.3 -0.1 0.2 -0.2 -0.4 0.3 0.2
Eye problems/disorders: Cataract 1.8 2.1 5.4 1.6 1.9 2.3 2.0 0.0 1.3 1.3 -0.1 -1.2 1.3 1.8 1.4 0.5 1.2 1.3 0.0 1.9 1.7 0.8 1.2 1.3 1.7 0.1 1.7 1.8 1.7 1.5 1.8 1.8 1.2 1.2
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 1.4 -0.5 0.2 0.3 0.1 0.0 0.1 0.1 0.3 0.2 -0.3 0.7 0.7 -0.5 0.4 -0.1 0.0 0.9 0.1 0.1 0.2 -0.5 -1.2 0.6 -0.2 -0.6 -1.2 -1.1 -0.6 0.6 0.6 0.3
Medication for cholesterol 3.8 5.8 10.0 -2.9 -3.2 -1.8 -2.5 0.0 -2.6 -2.6 -1.9 2.6 -2.7 -2.9 -1.9 -2.4 -2.7 -2.6 0.0 -3.0 -3.1 -2.3 -2.7 -2.4 -2.5 -1.6 -2.1 -2.7 -2.6 -2.6 -2.6 -2.0 -1.6 -2.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.7 2.0 7.3 1.5 1.4 0.5 2.0 0.0 1.6 1.6 0.3 -1.9 1.6 1.1 2.7 1.8 1.1 1.8 0.0 1.1 1.7 1.6 1.2 1.9 1.8 1.3 0.3 0.8 1.6 2.0 1.1 0.0 0.2 0.8
Back pain experienced in last month 0.2 0.2 2.6 0.2 0.6 -0.4 0.3 0.0 -0.0 -0.1 -0.2 -0.1 0.1 0.9 1.6 0.4 0.1 -0.0 0.0 0.8 0.6 0.1 0.2 0.0 0.2 0.2 -0.4 -0.0 0.1 0.1 -0.0 -0.2 -1.0 -0.6
Mineral and other dietary supplements 1.0 1.3 3.7 -1.0 -1.9 0.1 -0.5 0.0 -1.0 -1.0 -1.4 1.2 -1.1 -1.8 -1.3 -1.8 -1.2 -1.0 0.0 -1.6 -1.5 -1.7 -1.3 -1.4 -0.6 -1.8 -0.5 -0.4 -0.6 -1.1 -0.3 -0.3 -0.2 -0.4
Breast cancer (self-reported) 0.4 0.5 1.8 1.0 1.1 0.6 0.3 0.0 0.6 0.6 0.5 -0.7 0.8 1.3 0.9 1.2 0.7 0.6 0.0 1.1 0.9 1.2 0.7 0.8 0.4 1.1 0.0 0.4 0.4 0.6 0.1 -0.1 -0.4 0.1
Asthma (self-reported) 1.2 2.5 6.4 -1.8 -1.6 -1.4 -0.3 0.0 -1.6 -1.6 -1.0 1.8 -2.0 -1.5 -2.5 -2.1 -1.1 -1.8 0.0 -1.2 -1.4 -1.6 -1.5 -2.1 -2.3 -0.7 -1.3 -1.6 -2.3 -2.4 -1.6 -0.6 -0.6 -0.9
Osteoporosis (self-reported) 4.7 5.8 14.1 2.2 3.1 3.2 3.1 0.0 2.2 2.2 1.2 -2.2 2.2 3.2 3.7 1.5 2.1 2.2 0.0 3.3 2.8 1.7 2.1 2.2 2.9 0.6 2.4 3.0 3.0 2.7 2.7 2.1 1.8 2.1
Osteoarthritis (self-reported) 0.8 1.0 2.2 1.1 1.1 -0.1 1.0 0.0 1.2 1.1 -0.1 -1.2 1.2 0.9 0.6 1.4 1.2 1.1 0.0 1.1 1.3 1.3 1.5 1.2 0.9 1.4 0.7 0.6 0.8 1.0 0.8 1.2 -0.2 0.3
Medication: Aspirin 0.2 0.2 1.4 0.2 -0.4 0.1 0.3 0.0 0.2 0.2 0.6 -0.4 0.2 -0.4 0.4 0.9 0.5 0.2 0.0 -0.9 0.2 0.9 0.2 0.5 -0.2 1.2 -0.2 -0.5 -0.2 0.4 -0.4 -0.6 -0.0 0.0
Medication: Gliclazide 0.8 0.9 2.9 -0.9 -1.7 -0.5 -1.2 0.0 -1.1 -1.0 0.3 0.9 -0.9 -1.2 -0.7 -0.4 -1.1 -1.0 0.0 -1.2 -1.1 -0.5 -1.0 -1.0 -1.4 -0.2 -0.6 -0.8 -1.2 -1.0 -1.0 -1.2 0.3 -0.2
Illnesses of father: None of the above (group 1) 0.6 0.7 2.0 1.0 0.9 0.8 0.4 0.0 1.1 1.1 0.2 -1.1 0.9 1.3 -0.1 0.9 1.0 1.0 0.0 1.2 1.0 1.2 0.8 1.1 0.5 1.4 0.5 0.3 0.4 0.7 0.2 0.9 0.3 0.5
Smoking status: Current 0.2 0.3 2.6 0.5 -0.2 -0.2 0.0 0.0 0.1 0.1 0.6 0.0 0.1 -0.6 0.0 -0.6 0.1 0.2 0.0 -0.4 -0.1 -1.0 0.2 -0.4 0.8 -1.6 0.4 1.2 0.9 0.1 1.1 0.4 -0.0 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 2.6 -0.1 0.9 -0.2 -0.2 0.0 0.1 0.1 0.4 -0.1 0.2 1.4 -0.5 0.6 0.1 0.0 0.0 1.6 0.6 0.6 0.3 0.1 -0.9 1.3 -0.1 -0.8 -0.8 -0.2 -0.5 -0.2 0.4 0.1
Whole body water mass 3.3 18.6 28.4 -4.5 -5.3 -5.0 -4.3 0.0 -4.8 -4.8 -2.7 5.0 -4.8 -5.3 -3.2 -4.6 -4.3 -4.9 0.0 -5.1 -5.2 -4.9 -4.4 -5.3 -4.2 -3.8 -3.9 -3.6 -4.4 -5.2 -3.7 -3.0 -3.5 -3.9
Leg predicted mass (right) 3.9 20.9 31.9 -5.0 -5.5 -5.5 -4.3 0.0 -5.2 -5.2 -3.1 5.5 -5.3 -5.2 -3.2 -5.1 -4.8 -5.3 0.0 -5.0 -5.4 -5.3 -4.7 -5.7 -4.4 -4.4 -3.8 -3.6 -4.5 -5.5 -3.9 -3.0 -3.5 -4.1
Arm fat mass (left) 5.2 21.2 32.7 -5.3 -5.1 -5.0 -3.3 0.0 -5.5 -5.5 -4.4 5.7 -5.6 -4.3 -3.9 -5.5 -5.2 -5.5 0.0 -4.2 -5.3 -5.6 -5.2 -5.6 -4.0 -5.0 -3.5 -3.6 -4.2 -5.2 -3.7 -3.1 -3.4 -4.3
Number of self-reported non-cancer illnesses 0.7 1.3 4.7 1.5 1.1 0.5 2.2 0.0 1.1 1.1 0.5 -1.3 1.2 1.0 0.7 1.8 1.2 1.0 0.0 1.1 1.4 1.7 1.2 1.2 0.3 2.1 0.8 0.2 0.4 1.2 0.6 0.6 0.8 0.9
Average weekly champagne plus white wine intake 0.7 0.9 3.0 1.1 0.4 1.6 1.6 0.0 0.9 1.0 0.6 -1.2 1.1 0.1 1.2 1.7 1.0 0.9 0.0 -0.2 0.6 1.5 0.9 1.3 0.5 1.7 0.5 -0.1 0.5 1.1 0.1 0.2 0.2 0.4
Miserableness 0.7 1.2 3.3 1.3 1.0 1.5 0.2 0.0 1.2 1.2 1.4 -1.0 1.0 0.4 1.0 0.1 1.1 1.3 0.0 0.6 1.0 0.2 0.9 0.6 1.4 -0.7 1.1 1.8 1.6 1.0 1.7 1.0 1.2 1.6
Guilty feelings 0.3 0.4 1.5 -0.3 -0.6 -0.8 -0.8 0.0 -0.7 -0.6 0.8 0.7 -0.6 -0.4 -1.2 -0.9 -0.9 -0.6 0.0 -0.0 -0.5 -0.8 -0.7 -0.7 0.2 -1.2 -0.1 0.7 0.1 -0.4 0.2 -0.0 -0.2 -0.0
Wears glasses or contact lenses 0.1 0.2 1.7 0.4 0.3 -1.3 0.2 0.0 0.0 0.0 0.2 -0.2 0.1 1.0 -0.1 0.5 0.2 -0.0 0.0 0.3 0.5 0.0 0.1 0.3 -0.1 0.6 0.3 -0.6 -0.1 0.3 -0.1 0.1 -0.1 -0.2
Ever taken oral contraceptive pill 1.8 2.0 7.6 1.3 1.7 1.6 0.7 0.0 1.5 1.5 2.8 -1.5 1.6 2.0 0.4 1.6 1.4 1.5 0.0 1.9 1.5 1.7 1.4 1.5 1.6 1.1 0.7 1.6 1.5 1.5 1.1 0.9 0.3 1.1
Hearing aid user 0.2 0.2 0.8 -0.4 -0.5 -0.9 -0.6 0.0 -0.5 -0.5 0.5 0.4 -0.5 -0.5 -0.3 -0.1 -0.2 -0.5 0.0 -0.5 -0.4 -0.2 -0.3 -0.3 -0.5 0.1 -0.2 -0.8 -0.5 -0.3 -0.6 -0.4 -0.2 -0.7
Mother’s age at death 0.1 0.1 1.0 0.1 0.6 -0.4 0.6 0.0 0.2 0.1 -0.3 -0.3 0.1 0.8 0.2 0.2 0.1 0.2 0.0 1.0 0.4 0.1 0.3 0.1 -0.0 0.3 -0.5 -0.4 -0.1 0.0 -0.3 -0.4 -0.5 -0.3
Financial situation satisfaction 0.1 0.1 0.6 -0.1 -0.4 -0.1 -0.3 0.0 -0.0 -0.1 -0.5 0.2 -0.3 -0.2 -0.8 -0.3 0.4 -0.1 0.0 -0.8 -0.3 0.0 0.1 -0.1 -0.0 -0.2 0.1 0.1 -0.1 -0.3 -0.1 0.4 -0.1 -0.1
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.4 -0.8 -0.9 -0.3 -0.6 0.0 -0.9 -0.8 0.0 0.9 -0.9 -0.9 -1.2 -1.1 -0.8 -0.9 0.0 -0.9 -0.9 -0.8 -0.8 -1.1 -1.1 -0.7 0.4 -0.1 -0.8 -0.9 -0.2 -0.1 0.9 0.4
Commuting to job workplace: Public transport 0.1 0.1 1.6 0.0 0.4 -0.6 0.1 0.0 0.0 -0.1 1.3 0.0 0.0 0.7 0.6 0.1 0.2 -0.1 0.0 0.4 0.5 -0.1 0.2 0.2 0.3 -0.2 0.6 0.3 0.3 0.4 0.3 0.2 0.5 0.1
Eye problems/disorders: Glaucoma 0.3 0.4 2.0 0.9 0.5 0.4 -0.3 0.0 0.6 0.5 1.4 -0.4 0.5 0.2 0.2 -0.2 0.8 0.6 0.0 0.3 0.7 -0.3 0.6 -0.2 0.1 -0.4 0.6 0.8 0.3 0.0 1.0 0.5 1.0 1.2
Medication: Blood pressure 4.8 9.1 15.2 3.9 3.6 2.8 3.2 0.0 3.4 3.4 2.3 -3.5 3.7 2.8 3.1 3.5 3.1 3.6 0.0 2.8 3.9 3.1 3.2 3.2 3.4 2.3 1.9 3.2 3.5 3.5 3.2 1.9 1.1 2.6
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.6 0.1 -0.1 -0.3 0.7 0.0 0.0 0.1 -0.4 0.0 0.2 0.0 0.4 0.1 0.0 -0.0 0.0 0.2 0.0 0.3 0.3 -0.1 -0.6 0.6 0.8 0.2 -0.3 -0.2 0.3 0.8 0.7 0.7
Supplements: Fish oil (including cod liver oil) 1.5 1.9 5.6 1.4 1.7 0.0 0.7 0.0 1.6 1.6 1.3 -1.6 1.6 1.4 1.4 2.0 1.8 1.5 0.0 1.3 1.6 2.1 1.8 1.9 0.8 2.4 1.2 0.5 0.8 1.5 0.6 1.2 0.7 0.7
High cholesterol (Self-reported) 0.1 0.2 1.0 0.0 0.3 0.2 0.3 0.0 0.2 0.2 -1.0 -0.3 0.3 0.5 0.3 0.7 0.3 0.2 0.0 0.1 0.5 0.3 0.3 0.4 0.1 0.7 -0.1 -0.6 0.0 0.4 -0.2 0.0 -0.7 -0.4
Medication: Bendroflumethiazide 0.9 1.3 6.3 1.3 1.3 1.5 2.5 0.0 1.0 1.1 0.6 -1.4 1.3 1.0 1.5 1.7 0.7 1.2 0.0 0.9 1.5 1.7 0.8 1.4 1.1 1.4 -0.4 0.7 1.0 1.2 0.4 -0.5 -0.6 0.4
Medication: Paracetamol 0.6 0.9 5.0 0.9 0.8 2.2 2.0 0.0 0.6 0.6 0.6 -0.5 0.4 1.1 2.0 0.5 0.9 0.6 0.0 0.6 0.8 1.1 0.5 0.6 0.1 0.8 0.7 0.7 0.2 0.4 0.2 0.1 1.6 1.2
Medication: Lisinopril 2.3 3.0 5.5 1.6 2.1 0.9 1.0 0.0 1.9 1.9 2.1 -2.0 2.0 1.8 2.1 2.3 1.9 1.9 0.0 1.9 2.2 2.4 1.9 2.0 1.6 2.1 1.1 1.6 1.6 1.8 1.3 1.2 0.8 1.3
Medication: Atorvastatin 1.1 1.4 3.8 1.1 1.7 0.5 -0.2 0.0 1.4 1.4 1.9 -1.2 1.2 1.2 0.9 1.0 1.6 1.3 0.0 1.6 1.5 1.2 1.6 0.8 0.3 1.4 0.9 1.0 0.5 0.5 1.0 1.5 1.0 1.4
Illnesses of father: High blood pressure 0.4 0.5 2.5 -1.1 -0.7 -1.0 0.1 0.0 -0.5 -0.5 -1.1 0.6 -0.6 -1.1 1.3 -1.1 -0.8 -0.4 0.0 -0.9 -0.9 -1.1 -0.7 -0.5 0.3 -1.6 -0.4 -0.0 0.2 -0.3 0.1 -0.5 -0.4 -0.4
Alcohol drinker status: Never 0.7 0.8 2.0 1.3 0.6 -0.5 0.3 0.0 0.9 0.9 0.8 -1.1 1.1 0.6 0.9 1.4 0.9 0.9 0.0 0.6 1.1 1.3 1.0 1.3 0.9 1.3 0.8 0.6 0.9 1.3 0.7 0.7 0.4 0.5
Ever smoked 0.3 0.6 3.8 -0.0 -0.0 -1.9 -0.4 0.0 -0.3 -0.3 1.0 0.5 -0.3 -0.7 0.5 -1.2 -0.2 -0.3 0.0 -0.6 -0.2 -1.7 -0.3 -1.1 0.2 -1.9 -0.1 0.5 0.3 -0.5 0.8 0.2 -0.3 -0.0
Basal metabolic rate 4.1 22.8 34.6 -5.1 -5.8 -5.4 -4.5 0.0 -5.4 -5.4 -3.2 5.6 -5.5 -5.5 -3.8 -5.2 -4.9 -5.5 0.0 -5.4 -5.6 -5.5 -4.9 -5.9 -4.7 -4.4 -4.2 -4.0 -4.8 -5.8 -4.1 -3.3 -3.8 -4.3
Leg fat percentage (left) 4.6 16.7 29.7 -4.6 -4.3 -4.4 -2.3 0.0 -5.0 -4.9 -4.2 5.2 -5.1 -3.5 -3.9 -5.3 -4.6 -5.0 0.0 -3.5 -4.5 -5.4 -4.7 -5.1 -3.5 -4.8 -2.7 -3.1 -3.6 -4.6 -3.0 -2.3 -2.7 -3.7
Arm fat-free mass (left) 3.5 17.9 26.9 -4.5 -5.1 -5.0 -3.8 0.0 -4.7 -4.7 -2.9 4.9 -4.8 -5.0 -3.4 -4.6 -4.2 -4.8 0.0 -5.0 -5.0 -4.9 -4.3 -5.2 -4.1 -3.9 -3.7 -3.6 -4.3 -5.1 -3.6 -2.8 -3.5 -3.9
Number of operations (self-reported) 2.4 3.5 8.3 2.1 1.9 2.6 1.8 0.0 2.0 2.0 1.3 -2.3 2.2 1.5 2.2 2.9 1.8 2.1 0.0 1.5 2.1 2.9 1.9 2.5 1.6 2.8 0.9 1.1 1.6 2.3 1.0 0.6 0.6 1.2
Average weekly beer plus cider intake 0.4 0.6 2.6 0.8 0.4 0.7 0.6 0.0 0.7 0.7 0.1 -0.4 0.6 -0.1 0.5 -0.1 0.7 0.7 0.0 0.1 0.4 -0.2 0.6 0.3 0.8 -0.6 1.5 1.2 1.0 0.7 1.6 1.3 1.6 1.2
Irritability 0.6 1.1 3.3 0.9 1.3 0.0 0.1 0.0 0.4 0.4 1.7 -0.3 0.5 1.3 1.8 0.1 0.5 0.5 0.0 0.9 0.9 -0.4 0.7 0.5 1.8 -1.4 1.2 1.8 1.8 1.2 1.7 1.0 0.6 0.6
Risk taking 0.4 0.6 1.8 -0.4 -0.5 -1.3 -0.6 0.0 -0.8 -0.8 0.3 0.8 -0.8 -0.7 -0.7 -1.0 -0.6 -0.8 0.0 -0.8 -0.6 -1.1 -0.8 -1.2 -1.2 -0.8 -0.4 -0.5 -1.0 -1.1 -0.4 -0.7 0.2 0.1
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.5 0.9 0.4 0.5 0.3 0.0 0.8 0.7 0.9 -0.8 0.8 0.0 -0.2 0.9 0.6 0.8 0.0 0.1 0.5 0.6 0.8 1.1 1.2 0.2 0.6 0.7 1.1 1.2 0.8 0.4 0.3 0.4
Fractured/broken bones in last 5 years 1.0 1.3 3.8 1.5 1.2 1.9 0.3 0.0 1.0 1.0 1.9 -1.1 1.1 1.5 0.4 1.3 0.9 1.1 0.0 1.2 1.1 1.7 0.7 1.5 1.3 1.1 0.4 1.0 1.2 1.4 0.4 0.1 0.4 0.6
Age started oral contraceptive pill 0.2 0.3 0.7 -0.5 -0.2 -0.3 0.2 0.0 -0.7 -0.7 -0.5 0.7 -0.6 -0.1 0.6 -0.5 -0.7 -0.8 0.0 0.2 -0.3 -0.5 -0.6 -0.8 -0.8 -0.3 -0.3 -0.2 -0.7 -0.8 -0.4 -0.3 -0.2 -0.2
Diastolic blood pressure, automated reading 0.9 2.8 8.6 -1.9 -1.4 -1.5 -0.2 0.0 -2.0 -2.0 -2.9 1.8 -1.8 -0.9 -1.8 -1.6 -2.0 -1.9 0.0 -1.0 -1.5 -2.0 -1.8 -1.5 -1.1 -1.5 -1.7 -1.9 -1.3 -1.4 -1.6 -1.5 -2.3 -2.5
Ever depressed for a whole week 0.9 1.1 4.5 0.8 0.9 0.1 0.5 0.0 0.4 0.4 1.5 -0.1 0.2 0.2 1.2 -0.9 0.3 0.5 0.0 0.4 0.5 -0.9 0.3 -0.0 1.6 -2.1 1.3 2.1 1.7 0.8 2.0 1.1 1.3 1.3
Unable to work because of sickness or disability 0.2 0.3 1.2 0.6 0.4 1.1 1.0 0.0 0.2 0.3 0.2 -0.3 0.4 0.9 0.7 0.7 0.3 0.3 0.0 0.5 0.6 0.6 0.4 0.5 0.5 0.4 0.5 0.6 0.6 0.6 0.5 0.3 0.3 0.4
Commuting to job workplace: Cycle 0.3 0.4 2.1 -0.1 -0.7 -0.3 0.1 0.0 -0.2 -0.2 0.1 0.4 -0.4 -1.2 1.0 -0.2 0.3 -0.3 0.0 -1.5 -0.8 -0.0 -0.0 -0.3 -1.1 0.7 -0.2 -1.0 -1.1 -0.8 -0.9 0.2 0.0 -0.4
Myopia 1.0 1.4 4.9 1.4 1.1 1.9 1.2 0.0 1.3 1.2 1.0 -1.4 1.3 0.9 2.2 1.4 1.0 1.3 0.0 1.1 1.5 1.0 1.1 0.9 0.8 0.9 0.5 1.1 0.9 1.2 1.1 -0.1 1.1 1.6
Vascular/heart problems diagnosed by doctor 2.6 7.0 15.1 -3.3 -2.8 -2.4 -3.8 0.0 -2.7 -2.8 -2.3 3.2 -3.1 -2.3 -2.5 -3.9 -2.6 -2.9 0.0 -1.9 -3.3 -3.7 -2.6 -3.4 -2.8 -3.3 -1.2 -2.0 -2.7 -3.4 -1.9 -1.0 -0.7 -1.7
Cholesterol lowering medication 0.8 1.2 3.0 1.2 1.4 -0.1 0.7 0.0 1.1 1.1 1.0 -1.2 1.4 1.2 0.9 1.3 1.0 1.2 0.0 0.9 1.3 1.1 1.1 1.4 1.7 0.5 0.9 1.4 1.7 1.6 1.4 0.7 0.1 0.7
Medication: Omeprazole (e.g. Zanprol) 1.1 1.4 4.3 -1.3 -1.5 -1.9 -0.4 0.0 -0.9 -0.9 -0.7 0.9 -1.2 -1.0 -1.3 -0.5 -0.5 -1.2 0.0 -1.6 -1.3 0.0 -0.7 -0.3 -1.6 0.9 -0.8 -2.1 -1.8 -1.3 -1.9 -0.1 -1.3 -1.5
Pain experienced in last month 0.1 0.1 1.8 0.1 0.2 0.2 -0.1 0.0 0.3 0.3 0.3 -0.3 0.3 0.1 -1.3 0.2 0.4 0.3 0.0 0.1 0.1 0.1 0.4 0.3 0.3 0.3 0.2 -0.0 0.2 0.2 0.2 0.7 -0.1 -0.0
Supplements: Calcium 1.3 1.4 5.5 1.1 1.9 0.5 1.0 0.0 0.9 0.9 1.7 -1.0 1.0 1.8 2.3 1.3 0.9 0.9 0.0 2.1 1.7 1.0 1.0 0.6 0.2 1.1 1.0 0.8 0.5 0.8 0.8 0.5 1.5 1.5
Basal cell carcinoma (self-reported) 3.1 3.7 8.3 2.5 1.6 1.6 2.9 0.0 2.2 2.2 1.2 -2.3 2.3 1.6 1.1 2.4 2.1 2.2 0.0 1.3 1.8 2.1 2.2 2.6 2.4 1.8 1.7 1.5 2.2 2.6 1.7 2.0 0.4 1.1
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.8 0.4 0.1 -0.1 0.3 0.0 0.6 0.6 0.8 -0.5 0.4 0.5 0.2 0.6 0.9 0.5 0.0 -0.2 0.3 0.7 0.6 0.7 0.2 0.8 0.6 0.1 0.2 0.4 0.1 0.8 0.5 0.4
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 2.7 -0.2 -0.1 -1.1 0.1 0.0 0.3 0.3 -0.2 -0.0 -0.0 0.4 -1.6 -0.5 0.6 0.1 0.0 0.5 0.2 -0.1 0.6 0.2 0.4 -0.2 0.6 0.3 0.3 -0.0 0.3 1.6 -0.3 -0.3
Heart disease (siblings) 0.3 0.3 2.5 0.3 0.3 -0.2 0.1 0.0 0.5 0.5 0.4 -0.5 0.4 0.6 0.6 0.8 0.7 0.4 0.0 0.3 0.4 1.2 0.6 0.8 -0.3 1.6 0.5 -0.5 -0.3 0.3 -0.3 0.6 0.3 0.3
Alcohol drinker status: Previous 2.6 3.0 8.6 1.8 1.9 1.5 2.0 0.0 1.7 1.7 1.0 -1.7 1.8 1.9 2.9 1.1 1.5 1.9 0.0 2.1 1.8 1.0 1.5 1.7 2.2 0.0 1.9 2.0 2.3 2.1 2.2 1.5 1.3 1.6
Pack years of smoking 0.9 1.4 4.2 1.7 0.8 0.5 1.7 0.0 1.0 1.0 -0.1 -0.8 1.0 1.1 0.1 0.6 1.4 0.9 0.0 0.5 0.9 0.6 1.3 1.0 1.7 -0.1 1.9 1.8 1.8 1.4 1.8 2.1 0.9 0.9
Impedance of whole body 0.2 0.9 4.6 -0.2 1.3 0.9 0.8 0.0 0.6 0.6 -0.1 -0.6 0.4 1.9 -1.1 0.4 0.5 0.5 0.0 2.1 1.0 0.8 0.5 0.7 -0.5 1.1 1.1 -0.3 -0.2 0.5 0.1 0.3 2.1 1.3
Leg fat mass (left) 5.8 22.8 36.0 -5.3 -5.4 -5.1 -3.1 0.0 -5.7 -5.7 -4.5 6.0 -5.8 -4.6 -4.0 -5.8 -5.2 -5.8 0.0 -4.6 -5.4 -6.0 -5.3 -6.0 -4.4 -5.1 -3.5 -3.7 -4.6 -5.6 -3.7 -2.9 -3.3 -4.2
Arm predicted mass (left) 3.7 18.9 28.6 -4.6 -5.2 -5.1 -4.1 0.0 -4.8 -4.8 -2.9 5.0 -4.9 -5.2 -3.6 -4.7 -4.4 -4.9 0.0 -5.1 -5.1 -5.2 -4.5 -5.3 -4.2 -4.1 -3.7 -3.7 -4.3 -5.2 -3.6 -2.9 -3.6 -4.0