Best TWAS P=8.65e-17 · Best GWAS P=5.6e-11 conditioned to 0.95
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CREB3L2 | 0.05 | 0 | enet | 10 | 0.01 | 0.009 | -4.2 | -6.2 | 5.2e-10 | 0.55 | 0.08 | 0.53 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CREB3L2 | 0.01 | 0 | blup | 94 | 0.01 | 0.010 | -6.0 | -8.3 | 8.7e-17 | 0.78 | 0.02 | 0.65 | TRUE |