Hub : Genes

COL24A1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1430	0.0350	1.7e-08	0.107	0.079	0.122	0.108	0.109	6.5e-13	7.8e-10	1.3e-14	4.3e-13	3.4e-13
2	METSIM	Adipose	0.0497	0.0205	1.9e-03	0.044	0.014	0.039	0.026	0.043	3.3e-07	2.8e-03	1.4e-06	6.4e-05	4.7e-07
3	ROSMAP	Brain Pre-frontal Cortex	0.1808	0.0351	2.1e-14	0.135	0.125	0.133	0.129	0.139	6.2e-17	9.8e-16	9.8e-17	2.9e-16	1.8e-17
4	TCGA	Breast Invasive Carcinoma	0.0348	0.0158	2.6e-03	0.005	0.009	0.016	NA	0.001	2.3e-02	5.0e-03	2.0e-04	NA	1.5e-01
5	TCGA	Glioblastoma Multiforme	0.2930	0.1160	4.4e-03	-0.005	0.063	0.030	NA	0.007	4.7e-01	5.5e-03	4.1e-02	NA	2.0e-01
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.1585	0.0500	1.0e-05	0.071	0.069	0.075	NA	0.076	1.9e-08	3.3e-08	8.7e-09	NA	6.0e-09
7	TCGA	Brain Lower Grade Glioma	0.1098	0.0417	1.6e-04	0.063	0.032	0.039	NA	0.051	1.1e-07	1.4e-04	2.4e-05	NA	1.6e-06
8	TCGA	Prostate Adenocarcinoma	0.0727	0.0336	4.0e-03	0.024	0.028	0.044	NA	0.037	1.4e-03	5.8e-04	1.9e-05	NA	8.9e-05
9	TCGA	Thyroid Carcinoma	0.2110	0.0480	1.2e-10	0.172	0.111	0.191	NA	0.185	1.8e-16	5.8e-11	2.4e-18	NA	9.6e-18

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.8	2.0	-0.5	-1.1	-0.1	-1.0	-0.3	-1.4	-1.4	-0.2	-1.0
Bipolar Disorder or Schizophrenia	0.1	0.2	0.9	-0.9	0.0	-0.3	-0.3	0.9	-0.0	-0.1	-0.0	-0.0
Depressed Affect (Nagel 2018)	0.9	1.9	4.0	0.5	-1.7	0.6	-1.3	-0.3	-1.8	-1.5	-2.0	-1.6
Depression (Nagel 2018)	0.5	0.7	1.6	0.7	-1.2	1.0	-1.0	-0.2	-0.8	-0.4	-1.3	-0.5
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.8	0.6	-0.8	0.4	-0.9	0.2	-0.6	-0.1	0.3	-0.3
Neuroticism (Nagel 2018)	0.4	0.9	1.9	0.4	-1.2	0.6	-0.4	-1.0	-1.1	-1.0	-1.0	-1.4
Schizophrenia (2018)	0.4	0.7	2.2	-0.7	0.9	-0.3	0.5	1.5	1.1	1.1	0.1	0.8
Schizophrenia vs Biploar Disorder	0.2	0.3	1.5	-0.8	0.0	-1.2	-0.1	0.6	0.2	0.2	-0.0	0.2
Worry (Nagel 2018)	0.4	0.8	2.3	-0.8	-0.7	-0.3	-0.0	-1.5	-0.8	-0.8	-0.9	-1.2
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.1	-0.3	-0.4	0.0	0.6	-0.2	-0.2	-0.1	-0.1
Alzheimer’s Disease (in father)	0.8	0.9	2.5	-1.1	0.7	-1.6	0.1	0.6	0.7	1.0	1.1	0.7
Alzheimer’s Disease (including proxy)	0.6	0.9	2.5	-1.2	-1.2	-1.6	-0.5	0.4	-1.1	-0.9	-0.5	-0.7
Crohns Disease (2017)	0.2	0.4	1.6	-0.1	0.4	-0.2	1.0	0.3	0.4	0.5	1.2	0.1
Irritable Bowel Disease (IBD)	0.1	0.3	1.1	-0.4	0.6	-0.3	0.4	0.1	0.5	0.4	1.1	0.0
Ulcerative Colitis (UC)	0.2	0.3	0.7	-0.7	0.7	-0.4	0.2	-0.1	0.7	0.5	0.8	0.2
Major Depression (MDD)	1.1	1.3	2.5	0.3	-1.3	0.2	-1.2	-1.2	-1.5	-1.6	-0.7	-1.5
Reaction Time	0.2	0.3	0.9	-0.4	-0.9	-0.8	-0.1	-0.1	-0.5	-0.3	-0.4	-0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.5	1.0	0.8	0.6	0.8	0.3	0.9	1.2	0.8	1.2
Breast Cancer	0.4	1.1	4.0	1.4	-1.0	2.0	-0.6	1.1	-0.7	-0.5	0.6	-0.4
Ovarian Cancer	0.2	0.3	1.2	0.9	-0.4	-0.0	-0.1	1.1	-0.1	0.1	-0.4	0.5
Prostate Cancer	0.1	0.2	0.5	-0.3	-0.6	-0.5	-0.2	0.7	-0.3	-0.1	0.3	0.0
Age at First Birth	0.6	0.9	2.7	1.2	-0.4	0.4	-1.6	0.5	-0.8	-1.0	-0.6	-1.1
Bipolar Disorder (2011)	0.4	0.4	2.1	1.1	-0.2	1.5	-0.5	-0.0	-0.0	-0.1	-0.3	0.0
Body Mass Index (BMI) (2010)	0.6	0.9	2.6	0.3	1.4	0.6	0.1	0.8	1.1	1.0	1.6	0.7
Coronary Artery Disease (CAD)	0.1	0.2	0.6	-0.3	0.1	-0.7	0.5	0.1	0.1	-0.1	-0.7	0.2
Crohns Disease (2012)	0.7	1.1	2.2	0.8	-1.3	0.7	-0.9	0.3	-1.5	-1.4	-0.1	-1.4
Mean Putamen Volume	0.6	0.7	3.1	1.8	0.2	1.7	-0.1	0.1	0.3	0.2	-0.4	-0.2
Fasting Glucose	0.9	1.0	2.3	-0.4	-1.5	-0.1	-1.3	0.6	-1.5	-0.9	-1.3	-0.3
HbA1C	0.8	0.9	2.3	0.8	-1.5	0.2	-0.9	0.8	-1.2	-1.4	-0.2	-0.7
HDL Cholesterol	0.9	1.6	3.2	0.2	-1.8	-0.4	-0.8	0.8	-1.6	-1.5	-1.7	-1.4
LDL Cholesterol	0.7	1.2	2.6	-0.1	-1.2	0.4	-1.1	-0.8	-1.3	-1.6	-1.0	-1.3
Lupus	0.4	0.6	3.3	-0.8	0.4	-0.9	0.2	-1.8	0.2	-0.2	0.5	-0.2
Neuroticism (2016)	0.3	0.4	0.8	0.3	-0.6	0.9	-0.1	-0.7	-0.8	-0.6	-0.6	-0.4
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.5	0.4	-0.2	0.1	-0.4	0.2	-0.0	0.2	0.1
Rheumatoid Arthritis	0.1	0.1	0.3	-0.6	0.4	-0.2	0.2	0.4	0.3	0.3	0.2	0.4
Schizophrenia (2014)	0.3	0.6	2.9	-1.7	-0.2	-1.1	-0.4	0.8	-0.2	-0.3	-0.3	-0.4
Triglycerides	0.1	0.2	0.7	-0.3	-0.0	-0.2	-0.7	0.8	-0.3	-0.3	0.0	0.1
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.1	-1.3	0.2	-0.5	1.4	0.3	0.6	1.0	1.3	1.4
Ulcerative Colitis	0.3	0.4	1.6	-0.0	0.8	0.4	0.0	0.5	0.9	0.6	1.2	0.4
Blood Eosinophil Count	0.1	0.7	1.7	-1.1	-0.6	-0.6	1.2	0.9	0.2	0.6	0.5	1.3
Blood Platelet Count	0.1	1.4	2.8	0.8	1.7	0.1	1.0	1.6	1.3	1.1	0.4	1.6
Blood Red Count	0.0	0.3	1.0	0.6	-0.5	0.4	1.0	0.6	-0.1	0.3	-0.4	0.3
Blood White Count	0.1	0.7	2.9	0.2	0.9	0.6	1.7	0.2	0.5	0.6	0.5	0.9
Heel T-Score	0.3	2.6	10.5	-3.2	-0.8	-2.7	-1.4	0.2	-1.0	-0.6	-1.1	-0.7
BMI	0.0	0.2	1.3	-0.1	-0.1	0.2	-0.1	-1.1	-0.1	0.1	-0.2	0.3
Height	1.0	19.4	86.7	-3.4	-2.8	-2.1	0.2	-9.3	-3.9	-4.5	-1.2	-5.2
Waist Hip Ratio (WHR)	0.6	2.6	19.4	1.3	0.5	-0.4	4.4	-0.2	0.3	0.0	1.2	0.3
Systolic Blood Pressure	0.3	1.6	3.3	-1.3	-1.4	-1.6	-1.8	1.4	-1.2	-0.5	-0.1	-1.0
Smoking Status	0.5	1.3	4.3	0.3	1.2	0.7	2.1	-0.6	1.1	1.0	1.1	1.3
Allergy or Eczema	0.1	0.4	1.1	1.0	-0.6	0.5	0.3	0.9	-0.3	-0.0	0.8	-0.1
Cardiovascular Disease	0.1	0.3	0.9	-0.6	-0.3	-0.7	-0.9	-0.4	-0.2	0.2	-0.7	-0.2
Hypothyroidism (self reported)	0.3	0.8	1.5	-0.3	-0.9	-0.5	-0.7	-1.2	-1.1	-1.1	-0.9	-0.5
Respiratory disease	0.5	1.1	3.6	-0.9	0.5	-1.2	1.2	-1.9	0.8	0.7	0.9	0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.2	-1.3	0.0	-1.5	0.4	-0.3	-0.2	-0.4	0.3	-0.3
Lung FEV1/FVC ratio	0.2	0.8	3.5	1.6	-0.1	1.9	-0.3	0.8	-0.5	-0.6	-0.5	0.1
Lung FVC	0.2	1.0	4.0	-0.8	-0.8	-0.1	-1.5	-0.1	-0.8	-1.0	-0.3	-2.0
Neuroticism	0.3	0.7	1.6	-0.2	-0.9	0.1	-0.0	-0.9	-1.0	-1.0	-1.1	-1.3
Chronotype (morning person)	0.1	0.2	1.0	0.1	0.5	0.0	0.2	1.0	0.3	0.4	-0.4	0.5
Hair Pigment	0.1	1.5	6.5	1.9	-0.0	2.5	-0.6	-1.5	-0.3	-0.4	-0.6	-0.5
Tanning	0.0	0.4	1.5	-1.2	-0.0	-1.2	0.2	0.6	-0.2	-0.1	-0.0	-0.3
Hand grip strength (left)	0.3	0.7	4.0	-0.2	0.6	-0.3	0.1	-1.1	0.3	-0.1	2.0	-0.8
Number of treatments/medications taken	0.7	1.3	3.5	-1.1	-1.9	-1.6	-0.2	-1.0	-1.4	-0.6	-0.9	-0.6
Average weekly spirits intake	0.4	0.5	2.2	0.3	-0.3	0.5	-0.4	0.0	-0.8	-0.9	-1.5	-0.5
Sensitivity / hurt feelings	0.8	1.5	2.8	0.5	-1.1	0.7	-0.9	-0.8	-1.4	-1.6	-1.7	-1.7
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.6	0.0	-0.8	0.2	-0.1	0.4	-0.4	0.1	-0.2	0.1
Hearing difficulty/problems: Yes	0.6	0.9	4.5	-2.1	0.1	-1.1	1.2	0.3	0.4	0.5	-0.6	0.7
Relative age of first facial hair	0.7	1.4	2.8	-0.1	-1.7	0.0	-1.3	-0.1	-1.5	-1.5	-1.1	-1.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.0	-0.4	0.8	0.1	0.4	0.3	1.0	0.8	-0.2	1.0
Ever used hormone-replacement therapy (HRT)	1.8	2.3	10.4	-2.7	0.1	-3.2	0.4	-1.4	0.3	0.4	-0.7	0.6
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.0	-0.5	-0.4	0.6	-0.2	-0.1	0.0	-0.5	0.0
Systolic blood pressure, automated reading	0.6	1.7	6.5	0.5	-1.8	0.1	-2.5	0.5	-1.5	-1.1	-0.7	-1.3
Eye problems/disorders: Diabetes related eye disease	1.2	1.4	2.6	-0.8	-0.1	-1.2	-1.0	-1.6	-1.0	-1.4	-1.4	-1.2
Angina	0.7	1.0	4.2	0.9	-0.5	1.1	-1.1	-0.7	-0.6	-0.5	-2.1	-0.2
Medication for hormone replacement therapy	1.2	1.3	5.9	-2.3	-0.3	-2.4	-0.1	0.4	-0.3	-0.1	0.1	-0.0
Vitamin and mineral supplements	0.3	0.4	1.1	1.1	-0.0	0.3	-0.9	0.8	-0.0	0.5	0.7	0.1
Supplements: Zinc	0.5	0.5	2.5	-0.7	0.0	-0.1	0.1	-0.2	-0.6	-0.9	-1.6	-0.6
Medication: Co-codamol	0.3	0.4	1.3	1.1	-0.8	0.9	-0.2	0.6	-0.4	-0.1	-0.5	-0.3
Medication: Metformin	0.9	1.2	2.8	-0.7	-1.4	-0.3	-1.3	-0.3	-1.7	-1.6	-0.4	-1.1
Diabetes (father)	1.1	1.4	2.3	0.7	1.2	1.2	1.4	-0.1	1.5	1.5	1.2	1.1
Diabetes (mother)	2.0	2.5	7.1	-1.8	-0.4	-1.0	-0.8	-2.7	-1.0	-1.3	-2.7	-0.9
Severe depression (siblings)	0.6	0.7	1.5	-0.0	1.2	-0.0	1.0	-0.0	1.1	1.1	0.1	1.2
Pack years adult smoking proportion	0.6	1.0	1.8	-0.0	1.3	0.1	1.0	-0.3	1.4	1.3	-0.6	1.3
Impedance of leg (right)	0.6	3.1	5.3	-1.8	-1.7	-2.3	-0.6	-1.1	-2.0	-1.8	-2.2	-1.7
Leg fat-free mass (left)	0.2	1.0	5.6	-0.9	-0.2	-0.0	1.2	-2.4	-0.1	-0.0	0.9	-0.1
Trunk fat percentage	0.1	0.3	0.7	-0.3	-0.4	-0.5	0.8	-0.9	-0.5	-0.0	-0.7	0.1
Hand grip strength (right)	0.6	1.5	5.4	-0.6	-0.2	-0.6	-1.0	-2.3	-0.7	-1.1	1.1	-1.9
Townsend deprivation index at recruitment	0.5	0.7	1.2	-1.1	-1.1	-0.7	-0.7	-0.7	-0.9	-0.5	-0.8	-0.6
Current tobacco smoking	0.2	0.4	2.1	-0.5	0.2	-0.2	1.4	-0.7	0.3	0.4	-0.1	0.5
Average weekly fortified wine intake	0.5	0.5	1.4	0.1	-1.1	-0.3	-0.5	0.2	-1.2	-1.0	-0.6	-0.8
Maternal smoking around birth	0.8	1.2	3.9	1.5	0.1	2.0	0.3	-2.0	0.0	-0.3	-0.7	-0.4
Fed-up feelings	0.3	0.6	1.3	1.0	-0.8	1.1	0.4	-0.2	-0.7	-0.5	-1.2	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	4.4	0.7	-1.3	1.1	-1.3	0.5	-1.3	-1.0	-2.1	-0.8
Relative age voice broke	0.5	0.7	2.6	0.9	-1.6	0.8	-0.6	-0.5	-1.0	-0.6	0.3	-0.8
Taking other prescription medications	0.7	1.0	6.6	-0.6	-0.2	-0.8	0.9	-2.6	-0.1	0.1	-0.7	0.1
Age when periods started (menarche)	0.9	2.1	5.6	2.4	-0.5	2.3	-2.0	-0.5	-0.8	-0.8	-0.9	-1.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.2	-0.1	-0.4	-0.3	-0.3	-0.6	-0.5	-0.4	-1.1	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.7	0.5	0.1	0.4	0.2	0.5	-0.1	-0.1	-0.8	-0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.6	-0.8	-0.7	-0.4	-0.4	-0.1	-0.5	-0.5	0.2	-0.7
Qualifications: CSEs or equivalent	0.8	1.0	5.0	0.2	0.6	0.1	0.6	2.2	1.0	1.1	0.2	1.0
Serious illness, injury or assault to yourself	0.2	0.3	2.1	-0.3	-0.1	-0.1	-0.2	-1.5	0.0	0.0	-0.5	-0.3
High blood pressure	0.3	0.9	2.8	-1.5	-1.0	-1.7	-1.3	-0.1	-0.7	-0.1	0.0	-0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.1	0.9	-0.8	0.7	0.2	-0.2	-0.5	-0.3	1.0	-0.1
Multivitamins +/- minerals	1.0	1.2	4.6	-2.1	0.6	-1.3	1.7	-0.7	0.8	0.3	-0.0	0.7
Stomach or abdominal pain in last month	0.3	0.4	1.5	0.5	0.2	0.7	-0.7	-1.2	0.0	-0.3	-0.2	-0.7
Supplements: Glucosamine	0.8	1.0	3.4	-1.0	-0.9	-1.0	1.1	-1.8	-0.7	-0.8	-0.6	-0.2
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.0	1.4	-0.1	1.7	0.5	0.3	0.2	0.5	-0.5	0.8
Medication: Atenolol	1.1	1.4	4.3	-0.3	1.0	0.0	1.0	1.0	1.3	1.8	0.3	2.1
Medication: Levothyroxine sodium	0.7	1.2	3.8	-0.0	-1.0	0.0	-2.0	-1.5	-1.1	-1.1	-0.7	-0.8
Sitting height	0.7	4.7	15.5	-2.4	-1.7	-2.1	-0.8	-3.9	-1.9	-1.9	0.1	-2.5
Chronic bronchitis/emphysema (father)	0.6	0.7	3.2	0.5	1.8	1.1	0.2	-0.8	0.9	0.3	0.6	-0.3
High blood pressure (mother)	0.2	0.3	1.0	-0.6	-0.6	-0.5	-1.0	-0.1	-0.7	-0.2	-0.4	-0.4
Body mass index (BMI)	0.2	1.0	2.6	0.5	0.9	0.6	1.6	0.3	1.0	1.3	0.7	1.4
Impedance of leg (left)	0.7	3.3	6.2	-1.5	-1.6	-2.1	-0.9	-1.3	-2.0	-2.0	-2.5	-2.0
Leg predicted mass (left)	0.2	0.9	5.3	-0.9	-0.2	-0.0	1.2	-2.3	-0.1	-0.1	0.9	-0.1
Trunk fat mass	0.2	0.7	2.7	-0.9	-0.6	-0.8	0.9	-1.7	-0.7	-0.3	-0.6	-0.2
Waist circumference	0.2	0.8	5.1	0.1	-0.4	0.1	2.2	-1.4	-0.3	-0.2	0.0	0.1
Number of incorrect matches in round	0.2	0.4	0.9	-0.2	-0.9	-0.6	-0.3	0.8	-0.5	-0.0	0.9	-0.4
Past tobacco smoking	0.1	0.2	0.7	0.1	-0.2	-0.2	-0.9	0.6	-0.2	-0.0	0.0	-0.6
Alcohol usually taken with meals	0.1	0.2	0.6	-0.6	0.4	-0.8	-0.1	0.0	0.4	0.2	0.3	0.1
Nervous feelings	0.0	0.1	0.2	-0.4	-0.1	0.2	-0.1	-0.5	-0.1	-0.1	-0.1	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.5	0.2	-0.7	0.6	0.1	-0.2	-1.1	-1.1	-0.6	-1.2
Hearing difficulty/problems with background noise	1.8	2.9	6.9	-2.6	-1.9	-1.9	0.1	-1.4	-1.7	-1.5	-2.0	-1.0
Hair/balding pattern: Pattern 2	0.6	0.8	3.3	-0.0	-0.9	0.0	-1.8	1.3	-0.5	-0.4	-0.9	0.2
Had menopause	0.7	0.8	3.2	-0.7	-0.7	-1.3	-0.5	-1.8	-0.5	-0.3	-0.9	-0.4
Had other major operations	0.7	0.9	2.5	-1.6	-1.2	-1.2	-0.3	-1.0	-0.6	-0.6	-0.0	-0.7
Forced vital capacity (FVC)	0.7	2.7	6.9	-1.5	-1.2	-0.9	-1.0	-2.6	-1.5	-1.7	-1.1	-2.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	-0.9	-0.3	-0.8	0.0	0.3	-0.5	-0.6	-1.0	-0.9
Ever unenthusiastic/disinterested for a whole week	2.9	3.5	7.2	-1.8	-1.5	-2.7	-0.3	-1.7	-1.9	-2.2	-1.5	-2.2
Qualifications: None of the above	0.6	1.2	7.8	-0.4	-0.7	0.1	-0.1	-2.8	-0.8	-0.8	-0.7	-0.8
Financial difficulties in last 2 years	0.3	0.3	0.9	-0.1	-0.5	-0.3	0.9	-0.9	-0.3	-0.5	-0.3	-0.8
Mouth/teeth dental problems	0.3	0.4	1.6	-0.6	-0.1	-0.3	0.4	-1.3	-0.5	-0.6	0.4	-0.8
Heart attack	1.0	1.3	2.3	-1.2	-0.9	-1.3	-1.3	-1.5	-0.9	-0.7	-1.4	-0.7
Allergy	0.2	0.4	2.0	-0.4	0.3	-0.6	-0.3	0.6	0.2	0.1	-1.4	-0.1
Pain all over the body in last month	0.3	0.3	0.8	-0.6	-0.1	-0.0	0.9	0.5	0.2	0.6	0.6	0.7
Diabetes (self-reported)	0.7	1.1	2.0	-0.8	-1.2	-1.1	-0.9	-0.5	-1.4	-1.4	-0.3	-1.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.1	0.5	-1.0	0.4	-0.5	0.3	-0.5	-0.2	-0.1	0.2
Medication: Ramipril	2.8	3.6	5.6	0.8	-1.6	1.6	-2.4	-2.2	-2.1	-2.0	-1.6	-2.3
Medication: Simvastatin	0.2	0.3	1.0	0.0	0.6	0.5	-0.6	0.3	0.6	1.0	0.2	0.7
Fluid intelligence score	0.3	0.5	2.1	-0.5	0.3	-0.8	0.6	0.5	0.4	1.0	-0.2	1.4
Illnesses of siblings	0.4	0.6	2.8	-0.1	-0.8	-0.7	0.2	1.7	-0.4	-0.4	-1.1	-0.3
Neuroticism score	0.3	0.7	1.5	-0.4	-0.7	0.2	-0.1	-0.9	-1.0	-1.0	-1.2	-1.2
Weight	0.2	1.1	5.9	-1.0	-0.5	-0.6	1.4	-2.4	-0.5	-0.3	0.3	-0.3
Impedance of arm (right)	0.1	0.6	1.4	1.1	-0.5	0.8	-1.2	1.0	-0.7	-0.4	-0.5	-0.4
Arm fat percentage (right)	0.2	0.8	1.9	1.1	0.7	1.0	0.8	0.6	0.6	1.0	0.0	1.4
Trunk fat-free mass	0.5	2.7	13.8	-2.3	-0.6	-1.3	0.9	-3.7	-0.8	-0.9	0.5	-1.0
Hip circumference	0.2	1.0	2.9	-1.0	-1.5	-0.4	0.1	-1.7	-1.1	-0.8	-0.5	-0.8
Time employed in main current job	0.7	0.8	3.0	-1.6	-0.9	-1.7	-0.4	-0.0	-0.7	-0.4	-0.2	-0.5
Alcohol intake versus 10 years previously	0.6	0.8	2.5	1.4	0.1	1.6	-0.6	1.4	0.3	0.4	-0.5	0.4
Father’s age at death	1.0	1.3	2.6	-0.0	1.4	-0.3	1.6	-0.5	1.4	1.3	1.4	1.4
Worrier / anxious feelings	0.8	1.5	3.6	0.1	-1.9	0.2	-0.6	-0.0	-1.8	-1.6	-1.2	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.0	0.4	-1.4	1.2	0.0	-0.4	-1.2	-0.7	-0.3	-0.5
Falls in the last year	0.8	1.1	4.3	-1.7	-0.3	-2.1	0.7	-1.5	-0.2	-0.2	-0.3	-0.0
Hair/balding pattern: Pattern 3	1.8	2.6	6.6	0.3	2.6	0.6	2.0	-0.2	2.0	1.8	1.6	1.7
Number of live births	0.4	0.5	2.2	1.4	-0.0	1.5	0.4	-0.7	0.0	-0.2	0.3	-0.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	4.8	-0.8	-1.2	-0.3	-1.3	-2.2	-1.6	-1.9	-1.3	-2.2
Pulse rate	0.4	0.6	4.6	0.3	0.4	-0.1	-0.1	-2.1	0.0	-0.1	0.7	-0.1
Happiness	0.2	0.3	0.5	-0.1	-0.4	-0.4	-0.6	0.3	-0.7	-0.7	0.5	-0.7
Noisy workplace	1.4	1.8	3.8	0.5	1.3	0.7	1.9	0.5	1.5	1.5	1.7	1.5
Qualifications: A levels/AS levels or equivalent	0.9	1.9	4.2	-0.7	-1.6	-0.9	-2.1	-0.3	-1.8	-1.7	-0.5	-1.8
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.6	-0.3	-1.1	0.0	-0.1	-1.6	-1.5	-1.9	-0.7	-1.5
Mouth/teeth dental problems: Dentures	0.5	0.8	2.2	0.0	-1.4	-0.6	-1.5	-0.3	-0.9	-0.6	-1.4	-0.1
Asthma	0.5	1.0	2.4	-0.5	0.6	-0.3	1.4	-1.5	0.8	0.8	1.3	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	3.1	1.8	-0.1	0.8	0.6	0.8	0.4	0.5	-0.1	0.6
Medication: Cholesterol lowering	0.2	0.3	1.1	-0.2	-0.3	-0.2	-0.5	-0.1	0.1	0.8	-0.3	1.1
Depression (self-reported)	0.2	0.3	1.1	0.2	-0.5	-0.1	1.0	-0.7	-0.5	-0.2	-0.3	0.2
Medication: Lansoprazole	0.9	1.1	2.8	0.6	1.3	0.6	1.2	-0.9	1.0	0.7	1.7	0.7
Prospective memory result	1.1	1.3	3.2	-0.5	-1.4	-0.4	-1.1	-1.8	-1.3	-1.2	0.3	-1.5
Lung cancer (father)	0.2	0.3	1.1	1.1	0.4	0.6	0.9	-0.2	0.0	0.1	0.3	0.1
Illnesses of mother	0.8	1.0	2.7	1.6	0.4	1.5	1.4	0.1	0.7	0.4	1.1	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.4	8.2	-1.2	-1.9	-1.1	-2.0	-2.6	-2.4	-2.6	-1.3	-2.9
Pulse wave Arterial Stiffness index	0.9	1.0	2.1	1.4	1.0	1.2	1.3	-1.0	0.8	0.5	0.3	0.9
Impedance of arm (left)	0.3	1.5	2.8	0.2	-1.3	-0.2	-1.6	-0.2	-1.7	-1.5	-1.3	-1.6
Arm fat mass (right)	0.0	0.2	0.8	0.3	0.1	0.5	0.9	-0.5	0.0	0.3	-0.0	0.5
Trunk predicted mass	0.5	2.7	13.8	-2.3	-0.6	-1.3	0.9	-3.7	-0.8	-1.0	0.5	-1.0
Standing height	1.2	11.5	38.6	-3.5	-2.9	-2.7	-0.5	-6.2	-3.3	-3.5	-1.1	-3.6
Length of working week for main job	0.2	0.2	0.7	0.5	0.1	0.8	-0.1	0.6	0.2	0.5	0.1	0.4
Exposure to tobacco smoke at home	0.6	0.7	2.9	-0.4	-0.0	-0.2	-1.1	-0.5	-0.5	-0.9	-1.7	-0.4
Breastfed as a baby	1.3	1.6	7.7	-2.2	-0.7	-2.8	0.3	-1.0	-0.1	-0.2	0.3	0.2
Tense / ‘highly strung’	0.6	0.9	4.4	-1.3	-0.3	-0.4	0.5	-2.1	-0.3	-0.5	-0.8	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.4	-0.0	-1.0	-0.6	0.6	-0.8	-1.2	-1.2	-0.1	-1.2
Hair/balding pattern: Pattern 4	2.3	5.5	12.1	-0.9	2.6	-0.6	3.5	-0.1	2.8	2.8	2.7	2.5
Birth weight of first child	0.1	0.2	0.6	-0.8	0.1	-0.3	-0.1	-0.7	-0.1	-0.2	0.4	0.3
Peak expiratory flow (PEF)	0.3	0.7	1.9	0.1	-0.3	0.8	-1.4	-0.6	-0.7	-1.0	-0.7	-1.0
Pulse wave reflection index	1.1	1.4	2.8	1.2	1.5	1.1	1.7	0.3	1.5	1.0	0.1	1.1
Ever highly irritable/argumentative for 2 days	1.1	1.3	3.8	1.9	1.1	1.9	0.5	1.0	1.0	0.8	0.1	0.7
Loud music exposure frequency	0.4	0.5	1.3	-0.7	0.8	-0.4	1.1	-1.1	0.4	0.5	0.1	-0.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.8	0.0	1.3	0.6	0.2	1.2	0.9	0.9	0.8	0.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	4.1	1.5	1.2	2.0	0.0	1.0	0.9	0.8	0.6	0.8
Blood clot in the leg (DVT)	0.8	1.0	4.7	0.6	-0.1	0.9	-0.1	1.5	0.3	0.7	2.2	0.5
Medication: Paracetamol	0.1	0.1	0.3	0.1	-0.1	0.4	0.5	-0.3	0.2	0.5	0.5	0.3
Headache pain in last month	0.3	0.4	3.1	-0.4	-0.2	-0.1	0.1	1.8	-0.3	-0.0	-0.8	-0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.5	0.1	1.0	-0.3	1.2	0.9	0.7	0.0	0.3	-0.1
Glaucoma (self-reported)	2.1	2.5	5.4	1.3	-0.9	1.0	-2.3	1.0	-1.4	-1.6	-2.2	-1.8
Gout (self-reported)	0.2	0.3	1.0	0.3	-0.6	-0.2	-0.4	-1.0	-0.5	-0.6	-0.5	-0.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	2.1	-0.3	-1.2	-0.1	-1.4	-1.3	-1.4	-1.4	-0.7	-0.9
Medication: Amlodipine	3.5	4.9	8.7	-0.8	-2.7	-0.8	-1.9	-2.2	-2.9	-2.9	-1.2	-2.9
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.6	-0.3	0.6	-0.9	1.2	-1.2	0.8	1.0	0.7	1.3
Birth weight	0.3	0.7	1.3	-0.5	-1.1	-0.6	-0.7	-0.6	-1.0	-1.1	-0.7	-0.8
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.8	-0.8	0.8	-0.3	0.3	-1.4	0.6	0.6	0.1	-0.0
High blood pressure (siblings)	0.7	1.0	5.1	-1.2	-0.0	-0.6	-1.0	-2.2	-0.4	-0.6	-0.6	-0.8
Forced vital capacity (FVC), Best measure	1.5	5.6	11.0	-2.3	-2.0	-2.0	-1.8	-3.3	-2.4	-2.5	-1.3	-3.0
Body fat percentage	0.1	0.3	1.2	-0.3	-0.1	-0.4	1.1	-0.5	-0.1	0.3	-0.7	0.5
Leg fat percentage (right)	0.2	0.5	2.5	-0.6	-0.2	-0.8	1.6	-0.2	-0.1	0.3	-0.7	0.8
Arm fat-free mass (right)	0.6	3.1	13.3	-2.6	-0.8	-1.8	1.0	-3.6	-0.9	-1.1	-0.1	-1.1
Exposure to tobacco smoke outside home	0.1	0.2	0.6	-0.8	-0.3	-0.6	-0.0	-0.6	-0.2	-0.1	-0.1	-0.2
Comparative body size at age 10	1.1	3.0	5.3	0.6	2.1	0.5	1.6	1.2	2.3	2.3	1.6	2.2
Number of full brothers	1.3	1.6	3.5	-0.1	1.1	-0.0	1.6	1.4	1.2	1.2	1.9	1.4
Worry too long after embarrassment	0.2	0.4	1.1	0.6	0.6	1.1	0.9	-0.2	0.5	0.3	0.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.2	0.1	1.2	-0.2	1.5	1.3	1.1	1.1	1.3	0.9
Wheeze or whistling in the chest in last year	0.3	0.5	1.2	0.9	0.2	0.9	0.6	-0.9	0.2	0.3	1.1	0.4
Number of children fathered	0.8	0.9	1.6	-0.8	-1.1	-0.8	-0.8	-0.9	-1.3	-1.2	-0.7	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.1	-1.0	-0.9	-1.0	-0.7	1.0	-0.1	0.3	-0.2	0.0
Age at first live birth	0.2	0.4	1.9	0.4	-0.2	0.1	-1.4	1.3	-0.0	0.1	-0.2	0.1
Pulse wave peak to peak time	1.0	1.1	2.5	-1.6	-1.2	-1.3	-1.2	0.6	-1.0	-0.7	-0.4	-1.1
Health satisfaction	0.2	0.2	0.7	-0.8	-0.3	-0.8	0.6	-0.1	-0.3	-0.1	-0.4	0.3
Shortness of breath walking on level ground	0.6	0.7	2.7	-1.2	0.0	-0.7	-0.2	-1.6	-0.2	-0.8	-0.8	-0.5
Qualifications: College or University degree	0.5	1.4	2.6	-0.7	-1.4	-0.9	-1.6	0.6	-1.6	-1.3	-0.8	-1.3
Eye problems/disorders: None of the above	0.2	0.3	0.8	-0.5	-0.6	-0.0	0.9	0.0	0.1	0.5	0.8	0.5
Mouth/teeth dental problems: Loose teeth	2.8	3.4	7.0	0.8	1.9	0.5	1.9	0.7	2.3	2.5	1.7	2.7
Emphysema/chronic bronchitis	0.3	0.3	0.9	0.1	-0.1	-0.3	-0.2	-0.8	-0.5	-0.8	-0.9	-0.3
Medication for pain relief, constipation, heartburn	0.4	0.7	2.7	-1.6	0.6	-1.2	-0.5	-0.5	-0.1	-0.8	-0.1	-0.8
Neck or shoulder pain in last month	0.3	0.5	0.9	0.1	0.7	0.3	0.9	-0.1	0.9	0.8	0.8	0.6
Medication: Blood pressure	0.5	0.8	3.2	-0.3	-1.0	-0.3	-1.4	-1.8	-1.0	-0.4	0.2	-0.4
Angina (self-reported)	0.7	0.9	3.8	0.8	-0.7	0.9	-1.2	-0.5	-0.7	-0.5	-1.9	-0.2
Migraine (self-reported)	0.3	0.4	2.0	0.1	-0.7	0.4	0.0	1.4	-0.6	-0.3	-0.5	-0.4
Medication: Ibuprofen	0.3	0.3	1.4	1.2	-0.4	-0.1	0.5	0.7	0.4	0.5	-0.1	0.6
Medication: Allopurinol	0.5	0.6	1.8	0.5	-1.1	0.2	-1.4	-0.4	-0.9	-0.8	-0.3	-0.7
Medication: Omeprazole	1.1	1.4	4.6	1.9	-1.0	2.1	-1.1	0.5	-0.7	-0.2	-1.1	0.1
Medication: Seretide 50 evohaler	1.8	2.1	5.5	2.3	0.4	2.2	1.3	1.0	0.9	1.3	1.1	1.3
Mean time to correctly identify matches	0.1	0.2	0.6	-0.5	-0.7	-0.8	-0.0	0.0	-0.1	0.0	-0.2	-0.4
Heart disease (mother)	0.7	0.8	1.9	-1.1	0.6	-1.4	0.8	-0.7	0.8	1.0	-0.1	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.9	0.1	0.6	-0.1	-0.8	1.4	0.5	0.5	-0.0	0.9
Whole body fat mass	0.1	0.5	1.7	-0.7	-0.2	-0.5	1.1	-1.3	-0.3	0.0	-0.5	0.2
Leg fat mass (right)	0.1	0.5	1.8	-0.9	-0.3	-0.6	1.3	-1.1	-0.3	0.0	-0.5	0.4
Arm predicted mass (right)	0.6	3.1	15.2	-2.5	-0.6	-1.7	1.3	-3.9	-0.7	-0.8	0.0	-0.8
Pulse rate, automated reading	1.0	3.2	5.4	1.7	-1.7	1.6	-1.0	-2.2	-2.0	-2.3	-0.9	-1.9
Alcohol intake frequency.	0.1	0.3	0.9	-0.3	-0.7	-0.9	-0.4	0.2	-0.7	-0.5	-0.4	-0.6
Comparative height size at age 10	1.6	8.7	20.7	-3.7	-2.8	-3.1	-0.5	-4.5	-3.0	-2.9	-1.4	-2.6
Number of full sisters	0.1	0.2	0.4	0.3	0.4	0.4	-0.1	-0.1	0.4	0.5	0.6	0.4
Suffer from ‘nerves’	0.6	1.0	4.1	-2.0	-0.3	-1.4	0.6	-1.0	-0.3	-0.4	0.4	-0.8
Overall health rating	0.2	0.5	1.3	0.8	-1.1	1.0	-0.3	-0.4	-0.8	-0.3	-0.6	-0.1
Chest pain or discomfort	0.5	0.7	2.8	-1.7	-0.7	-1.4	0.0	-0.6	-0.3	-0.4	-0.5	-0.5
Had major operations	1.5	1.7	7.0	-2.6	-0.8	-2.3	0.0	-1.3	-0.5	-0.2	-0.8	-0.4
Age at last live birth	0.3	0.4	1.1	0.7	0.9	0.7	-1.1	-0.4	0.5	0.4	-0.1	0.4
Family relationship satisfaction	0.5	0.7	1.2	-0.8	-0.4	-0.7	-1.0	-0.7	-0.8	-1.1	-0.5	-1.1
Leg pain on walking	0.1	0.1	0.5	0.4	-0.2	0.2	-0.7	0.1	-0.1	-0.2	0.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.8	6.1	1.0	1.9	0.6	2.5	1.6	2.5	2.4	2.1	2.1
Commuting to job workplace: Car/motor vehicle	1.0	1.1	4.0	1.9	0.1	2.0	0.1	-1.2	-0.1	-0.1	-1.2	0.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.3	-0.2	-0.3	-0.6	-0.6	-0.0	-0.2	-0.0	0.3	-0.2
Medication: Aspirin	0.2	0.3	0.9	1.0	0.2	0.3	-0.1	-0.1	0.4	0.8	0.7	0.6
Supplements: Vitamin C	0.6	0.7	3.5	0.2	-0.5	0.7	-0.1	-0.2	-0.8	-1.1	-1.9	-0.5
Knee pain experienced in last month	0.2	0.3	0.9	-0.6	0.4	-0.5	0.4	0.4	0.6	0.7	0.5	0.9
Hypertension (Self-reported)	0.3	0.7	2.6	-1.5	-0.8	-1.6	-1.0	-0.1	-0.6	0.1	0.1	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.2	-0.1	-1.1	-0.3	-0.5	0.5	-0.7	-0.2	-0.5	-0.2
Illnesses of father: Heart disease	3.3	4.6	9.4	1.2	2.3	1.0	2.1	1.0	2.8	3.1	1.9	2.8
Illnesses of siblings: Diabetes	0.3	0.4	2.5	-0.0	0.5	0.0	0.7	0.5	0.2	0.2	1.6	0.0
Smoking status: Previous	0.1	0.2	0.6	0.4	0.4	0.7	0.3	0.2	0.4	0.1	-0.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	5.8	-0.9	-2.1	-1.0	-0.9	-2.4	-2.3	-2.2	-0.8	-2.2
Whole body fat-free mass	0.3	1.9	10.4	-1.8	-0.3	-0.8	1.2	-3.2	-0.4	-0.5	0.7	-0.5
Leg fat-free mass (right)	0.2	0.9	5.6	-0.6	0.1	0.3	1.1	-2.4	0.1	0.0	1.0	-0.1
Arm fat percentage (left)	0.1	0.3	0.8	0.6	0.4	0.5	0.6	0.1	0.2	0.6	-0.3	0.9
Average weekly red wine intake	0.7	1.0	3.5	-1.9	0.0	-1.7	-0.5	-0.9	-0.1	-0.5	0.3	-1.0
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.9	-0.2	1.7	0.5	0.8	0.9	1.7	1.6	1.6	1.0
Mood swings	0.9	1.6	2.9	-0.8	-1.0	-1.3	-0.8	-0.6	-1.6	-1.3	-1.6	-1.7
Loneliness, isolation	0.4	0.5	1.8	0.8	-0.2	1.3	-0.5	0.2	-0.5	-0.4	-1.2	-0.3
Long-standing illness, disability or infirmity	0.6	0.9	5.2	-0.1	0.9	-0.5	0.5	-2.3	0.7	0.5	-0.7	0.6
Ever had bowel cancer screening	1.7	2.0	3.3	-0.5	-1.2	-0.5	-1.4	-1.4	-1.5	-1.8	-1.8	-1.7
Diabetes diagnosed by doctor	0.6	1.0	2.5	-0.4	-1.1	-0.5	-0.7	-0.8	-1.5	-1.6	-0.2	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.8	2.2	0.1	2.1	-0.6	-0.6	0.3	0.3	0.3	0.5
Friendships satisfaction	0.8	1.0	2.7	-0.8	-1.1	-0.7	-1.6	0.2	-1.1	-1.1	-0.7	-1.1
Qualifications: nursing, teaching	0.1	0.2	0.8	-0.6	0.1	-0.9	0.5	0.5	0.1	0.1	0.2	0.1
Commuting to job workplace: Walk	0.3	0.3	1.2	-0.2	0.2	-0.8	-0.6	1.1	0.2	0.1	0.4	-0.0
Eye problems/disorders: Cataract	0.2	0.2	0.4	0.4	0.6	-0.5	-0.2	0.3	0.5	0.2	0.5	0.3
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	3.3	-0.4	1.7	-0.2	1.4	1.1	1.8	1.7	1.2	1.3
Medication for cholesterol	0.7	1.0	2.2	1.0	1.0	1.5	0.9	-0.3	1.1	0.7	1.4	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.7	-0.2	-1.1	-0.3	-1.0	-0.5	-1.1	-0.8	-1.3	-1.0
Back pain experienced in last month	0.3	0.5	1.8	1.0	-0.6	0.7	-0.1	1.3	0.1	0.5	0.6	0.5
Mineral and other dietary supplements	0.4	0.5	1.8	1.4	-0.1	0.7	-1.1	0.9	-0.1	0.0	0.6	-0.2
Breast cancer (self-reported)	0.6	0.8	2.1	0.1	0.8	0.2	1.1	0.2	1.1	1.5	0.7	1.1
Asthma (self-reported)	0.4	0.7	2.3	-0.3	0.2	-0.3	1.1	-1.5	0.6	0.7	1.3	0.4
Osteoporosis (self-reported)	0.3	0.4	1.8	0.4	-0.7	-0.7	-1.4	0.3	-0.4	-0.2	0.3	-0.4
Osteoarthritis (self-reported)	0.6	0.8	1.3	-0.2	1.1	-0.2	0.9	-0.6	1.1	1.0	1.1	1.0
Medication: Aspirin	0.8	1.0	2.0	1.3	0.6	0.6	0.3	0.7	1.0	1.4	1.2	1.2
Medication: Gliclazide	2.3	2.6	4.5	-1.7	-1.9	-1.1	-0.8	-0.8	-2.0	-1.9	-1.4	-2.1
Illnesses of father: None of the above (group 1)	2.9	3.6	7.2	-0.1	-2.7	-0.5	-2.2	0.9	-2.6	-2.3	-1.9	-1.9
Smoking status: Current	0.3	0.4	2.1	-0.2	0.4	-0.0	1.4	-1.0	0.3	0.4	-0.0	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.5	0.3	1.2	0.2	-0.7	-1.2	0.8	0.4	0.8	-0.2
Whole body water mass	0.3	1.9	10.9	-1.8	-0.4	-0.8	1.1	-3.3	-0.5	-0.6	0.6	-0.7
Leg predicted mass (right)	0.2	0.9	5.3	-0.5	0.1	0.4	1.2	-2.3	0.1	0.1	1.1	-0.1
Arm fat mass (left)	0.1	0.2	0.9	0.1	0.1	0.1	1.0	-0.9	-0.0	0.2	0.1	0.4
Number of self-reported non-cancer illnesses	0.3	0.6	2.1	-0.9	-1.5	-0.9	-0.1	-0.6	-0.9	-0.4	-0.3	-0.4
Average weekly champagne plus white wine intake	0.4	0.5	1.8	0.7	-0.7	0.4	-0.5	1.3	-0.9	-0.7	-0.2	-0.1
Miserableness	1.2	2.1	4.5	1.7	-1.2	2.1	-1.3	1.3	-1.3	-1.0	-1.6	-1.2
Guilty feelings	0.5	0.7	2.2	1.3	0.5	1.5	1.4	-0.4	0.5	0.2	0.2	0.2
Wears glasses or contact lenses	1.6	1.8	5.1	-1.6	-1.4	-2.2	-1.0	-1.8	-0.8	-0.4	-1.2	-0.4
Ever taken oral contraceptive pill	0.6	0.6	2.8	-1.7	-0.3	-0.9	0.6	0.2	-0.2	-0.1	-1.2	0.3
Hearing aid user	0.8	0.9	1.6	0.9	0.8	0.7	0.6	0.9	1.1	1.2	0.8	1.2
Mother’s age at death	0.1	0.1	0.4	-0.6	0.0	-0.4	-0.1	-0.0	-0.0	-0.1	-0.3	0.2
Financial situation satisfaction	1.3	1.6	3.5	0.7	1.9	0.6	1.5	-0.2	1.6	1.3	1.1	1.3
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.5	0.3	0.8	0.2	1.6	-0.8	0.7	0.5	0.3	0.5
Commuting to job workplace: Public transport	0.3	0.3	1.1	-1.0	0.3	-0.6	0.4	1.0	0.3	0.3	-0.0	0.3
Eye problems/disorders: Glaucoma	2.0	2.4	6.2	1.8	-0.3	1.3	-2.0	0.1	-1.2	-1.5	-2.5	-1.6
Medication: Blood pressure	0.9	1.7	3.9	-1.9	-1.2	-2.0	-1.2	0.0	-1.2	-0.7	-1.7	-0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.6	-0.6	-1.1	-1.3	-0.4	-0.2	-0.7	-0.5	-0.1	-0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.7	-1.1	-0.1	-0.1	0.5	-1.3	-0.3	-0.6	-0.7	-0.5
High cholesterol (Self-reported)	0.3	0.6	1.8	0.3	0.8	-0.5	-0.0	0.8	1.0	1.4	0.1	1.0
Medication: Bendroflumethiazide	1.2	1.8	6.9	-2.6	-0.6	-2.5	-0.1	-0.9	-0.6	-0.1	-1.2	0.2
Medication: Paracetamol	0.1	0.2	0.4	-0.2	-0.2	-0.1	0.6	0.4	0.3	0.6	0.1	0.6
Medication: Lisinopril	0.4	0.6	1.8	-1.3	-0.4	-1.3	0.0	-0.4	-0.0	0.6	1.0	0.3
Medication: Atorvastatin	0.6	0.7	2.1	-0.4	-0.6	-1.4	-0.7	0.0	-1.1	-1.0	-0.4	-0.9
Illnesses of father: High blood pressure	0.3	0.3	0.7	-0.3	0.8	0.1	0.3	-0.6	0.8	0.5	0.7	0.7
Alcohol drinker status: Never	1.1	1.4	7.6	-1.4	0.0	-2.8	1.2	-0.4	0.4	0.6	0.8	0.0
Ever smoked	0.1	0.2	1.0	-0.3	-0.0	0.4	1.0	-0.6	-0.0	-0.1	0.0	0.3
Basal metabolic rate	0.3	1.6	9.1	-1.5	-0.3	-0.6	1.4	-3.0	-0.4	-0.4	0.7	-0.4
Leg fat percentage (left)	0.1	0.4	1.9	-0.4	-0.0	-0.6	1.4	-0.3	-0.1	0.2	-0.9	0.6
Arm fat-free mass (left)	0.4	1.8	10.4	-1.6	-0.4	-0.8	1.1	-3.2	-0.5	-0.6	0.4	-0.7
Number of operations (self-reported)	1.1	1.7	5.0	-2.2	-1.2	-1.9	0.1	-1.8	-0.8	-0.6	-0.8	-0.6
Average weekly beer plus cider intake	0.8	1.2	2.3	0.5	0.9	0.6	1.3	0.9	1.3	1.3	1.5	0.9
Irritability	0.1	0.2	0.6	-0.7	-0.8	-0.5	0.3	0.3	-0.5	-0.1	-0.4	-0.3
Risk taking	0.5	0.7	2.9	-1.0	0.2	-0.8	0.2	-1.7	0.0	-0.2	-1.2	-0.2
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.2	1.5	-0.5	1.3	0.7	-0.7	-0.2	-0.5	1.3	-0.5
Fractured/broken bones in last 5 years	0.6	0.7	1.2	-1.0	0.7	-0.4	1.0	-1.1	1.0	0.8	0.4	0.7
Age started oral contraceptive pill	0.3	0.4	1.9	-0.0	0.3	-0.1	-0.0	1.4	0.4	0.7	-0.1	0.9
Diastolic blood pressure, automated reading	0.4	1.2	6.2	1.8	-0.4	2.5	-0.9	0.4	-0.0	0.0	0.2	-0.1
Ever depressed for a whole week	6.8	8.3	15.3	-2.2	-3.0	-2.9	-2.0	-2.1	-3.4	-3.6	-2.1	-3.9
Unable to work because of sickness or disability	0.3	0.3	1.1	0.8	-0.4	0.7	1.0	0.2	-0.0	0.4	0.1	0.7
Commuting to job workplace: Cycle	0.3	0.4	0.7	-0.4	-0.7	-0.1	-0.6	-0.6	-0.8	-0.8	-0.4	-0.9
Myopia	0.9	1.3	2.3	-1.5	0.8	-0.8	1.4	0.9	1.0	1.0	1.4	1.1
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.2	1.1	1.0	1.1	1.1	0.3	0.6	-0.1	0.5	-0.0
Cholesterol lowering medication	0.3	0.4	1.9	1.4	0.3	0.7	-0.6	1.1	0.0	0.2	0.2	0.1
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	5.5	2.2	-0.7	2.3	-0.5	0.7	-0.2	0.3	-0.1	0.7
Pain experienced in last month	0.1	0.2	0.5	0.7	0.3	0.7	0.3	0.5	0.3	0.1	0.6	0.1
Supplements: Calcium	0.4	0.5	1.2	-0.2	-1.0	-0.2	0.3	-0.1	-0.7	-1.0	-0.5	-1.1
Basal cell carcinoma (self-reported)	1.5	1.8	3.7	0.8	-1.1	0.6	-1.6	-0.4	-1.7	-1.8	-1.1	-1.9
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.7	-0.9	-1.1	-1.0	-1.6	-1.5	-1.1	-0.9	-1.3	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.9	0.6	-0.1	0.9	-0.2	1.5	0.2	0.6	2.0	0.4
Heart disease (siblings)	0.2	0.2	0.5	0.1	0.4	0.1	-0.6	-0.5	-0.4	-0.4	-0.7	-0.5
Alcohol drinker status: Previous	1.9	2.2	5.7	-0.1	-2.4	-0.2	-1.3	1.2	-2.1	-1.8	-0.1	-1.8
Pack years of smoking	0.8	1.1	2.4	0.1	1.5	0.3	1.0	-0.8	1.4	1.2	-0.8	1.4
Impedance of whole body	0.5	2.6	4.6	-0.5	-1.7	-1.1	-1.6	-0.7	-2.0	-1.9	-2.1	-1.9
Leg fat mass (left)	0.1	0.5	1.6	-0.7	-0.3	-0.5	1.2	-1.3	-0.3	-0.1	-0.6	0.2
Arm predicted mass (left)	0.4	1.9	10.2	-1.7	-0.6	-1.0	1.0	-3.2	-0.6	-0.7	0.3	-0.8