Best TWAS P=1.78e-07 · Best GWAS P=1.96e-09 conditioned to 1.57e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARHGAP12 | 0.14 | 0.03 | lasso | 5 | 0.05 | 1.2e-03 | -3.8 | -5.2 | 1.8e-07 | 0.67 | 0.02 | 0.74 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF438 | 0.07 | 0.03 | lasso | 5 | 0.04 | 1.9e-05 | 3.7 | 5.2 | 2.5e-07 | 0.18 | 0.02 | 0.97 | TRUE |