TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Standing height
:
←
→
chr10:87,819,082-90,425,396
Best TWAS P=8.21e-10 · Best GWAS P=3.1e-13 conditioned to 5.84e-06
88M
88.5M
89M
89.5M
90M
90.5M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Heart Left Ventricle
BMPR1A
0.12
-0.01
enet
37
0.01
7.3e-02
3.5
6.1
8.2e-10
0.05
0.03
0.21
TRUE
1
CommonMind
Brain Pre-frontal Cortex
PTEN
0.07
0.00
blup
450
0.01
6.0e-02
-4.0
5.5
4.2e-08
0.55
0.01
0.95
TRUE
3
GTEx
Skin Sun Exposed Lower leg
SNCG
0.09
0.01
enet
9
0.05
6.3e-05
5.4
5.2
2.6e-07
0.04
0.00
1.00
TRUE