[Hub]/) : Traits : Standing height :

chr2:15,703-988,346

Best TWAS P=1.08e-15 · Best GWAS P=3.03e-14 conditioned to 0.000347

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SH3YL1 0.11 0.12 lasso 2 0.13 5.8e-16 -7.6 5.5 3.4e-08 -0.91 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous SH3YL1 0.08 0.10 lasso 1 0.08 4.1e-07 6.7 6.8 1.5e-11 -0.47 0.67 0.33 FALSE
3 GTEx Adipose Visceral Omentum SH3YL1 0.15 0.03 lasso 4 0.01 6.5e-02 4.8 6.9 6.0e-12 -0.53 0.08 0.55 FALSE
4 GTEx Artery Tibial SH3YL1 0.10 0.02 lasso 3 0.01 2.9e-02 6.7 6.6 3.2e-11 -0.63 0.06 0.91 FALSE
5 GTEx Cells Transformed fibroblasts SH3YL1 0.16 0.09 lasso 7 0.10 3.3e-08 -7.6 7.2 8.9e-13 -0.93 0.01 0.99 FALSE
6 GTEx Colon Sigmoid SH3YL1 0.20 0.14 lasso 3 0.14 1.3e-05 6.7 6.8 1.0e-11 -0.46 0.10 0.76 FALSE
7 GTEx Colon Transverse SH3YL1 0.36 0.25 lasso 7 0.26 1.2e-12 6.6 -6.5 6.1e-11 0.48 0.67 0.33 FALSE
8 GTEx Esophagus Gastroesophageal Junction SH3YL1 0.21 0.09 lasso 7 0.14 1.3e-05 4.2 5.5 3.7e-08 -0.42 0.24 0.55 FALSE
9 GTEx Esophagus Mucosa SH3YL1 0.60 0.67 lasso 4 0.66 9.2e-58 6.8 -6.6 3.7e-11 0.44 0.64 0.36 FALSE
10 GTEx Esophagus Muscularis SH3YL1 0.30 0.23 enet 50 0.28 4.6e-17 6.7 6.9 6.5e-12 -0.56 0.67 0.33 FALSE
11 GTEx Heart Atrial Appendage SH3YL1 0.27 0.23 lasso 6 0.22 2.1e-10 6.7 6.5 9.3e-11 -0.45 0.67 0.33 FALSE
12 GTEx Heart Left Ventricle SH3YL1 0.14 0.11 enet 16 0.10 8.2e-06 6.7 8.0 1.1e-15 -0.59 0.36 0.55 TRUE
13 GTEx Lung SH3YL1 0.09 0.08 lasso 5 0.05 8.5e-05 6.7 -5.5 4.5e-08 0.37 0.61 0.27 FALSE
14 GTEx Muscle Skeletal SH3YL1 0.12 0.10 lasso 3 0.09 4.1e-09 6.7 6.6 5.2e-11 -0.47 0.67 0.33 FALSE
15 GTEx Nerve Tibial SH3YL1 0.33 0.23 enet 35 0.25 5.6e-18 6.7 6.9 5.6e-12 -0.49 0.67 0.33 FALSE
16 GTEx Pancreas SH3YL1 0.48 0.43 lasso 11 0.41 6.9e-19 6.8 -6.7 2.3e-11 0.46 0.66 0.34 FALSE
17 GTEx Skin Not Sun Exposed Suprapubic SH3YL1 0.47 0.53 lasso 2 0.53 2.1e-33 6.7 -6.7 1.7e-11 0.47 0.67 0.33 FALSE
18 GTEx Skin Sun Exposed Lower leg SH3YL1 0.42 0.44 lasso 5 0.45 3.3e-41 6.7 -6.7 1.6e-11 0.46 0.66 0.34 FALSE
19 GTEx Stomach SH3YL1 0.33 0.21 lasso 6 0.20 3.8e-10 6.7 -6.7 2.6e-11 0.54 0.69 0.31 FALSE
20 GTEx Thyroid SH3YL1 0.29 0.32 lasso 4 0.31 2.9e-24 6.8 -6.7 2.9e-11 0.45 0.66 0.34 FALSE
21 GTEx Whole Blood SH3YL1 0.21 0.17 lasso 6 0.18 2.6e-16 6.8 -6.8 1.3e-11 0.47 0.67 0.33 FALSE
22 METSIM Adipose SH3YL1 0.03 0.02 lasso 3 0.02 9.5e-04 4.2 5.3 1.2e-07 -0.34 0.37 0.33 FALSE
23 NTR Blood SH3YL1 0.12 0.17 lasso 5 0.16 6.2e-51 6.7 -6.3 2.1e-10 0.40 0.69 0.31 FALSE
24 ROSMAP Brain Pre-frontal Cortex ACP1 0.03 0.04 lasso 2 0.02 4.7e-04 6.7 -6.6 4.6e-11 0.46 0.48 0.22 FALSE
25 ROSMAP Brain Pre-frontal Cortex FAM150B 0.06 0.01 bslmm 381 0.03 9.9e-05 -7.2 -7.3 2.7e-13 0.71 0.01 0.96 FALSE
26 YFS Blood SH3YL1 0.48 0.40 enet 100 0.46 3.2e-171 6.7 -5.7 9.3e-09 0.34 0.68 0.32 FALSE
27 The Cancer Genome Atlas Bladder Urothelial Carcinoma SH3YL1 0.25 0.15 blup 67 0.18 2.8e-15 6.8 -5.8 4.9e-09 0.16 0.70 0.30 FALSE
28 The Cancer Genome Atlas Breast Invasive Carcinoma SH3YL1 0.19 0.31 lasso 5 0.32 2.5e-66 6.6 -6.2 6.5e-10 0.38 0.70 0.30 FALSE
29 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma SH3YL1 0.32 0.27 enet 14 0.28 6.6e-14 6.7 -5.5 4.8e-08 0.25 0.69 0.31 FALSE
30 The Cancer Genome Atlas Colon Adenocarcinoma SH3YL1 0.32 0.34 lasso 6 0.35 2.8e-21 6.8 -6.6 4.2e-11 0.45 0.68 0.32 FALSE
31 The Cancer Genome Atlas Esophageal Carcinoma SH3YL1 0.16 0.02 blup 67 0.08 1.9e-03 6.7 -8.0 1.9e-15 0.51 0.10 0.33 FALSE
32 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SH3YL1 0.24 0.25 lasso 4 0.25 8.1e-28 6.7 -6.7 1.6e-11 0.48 0.71 0.29 FALSE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SH3YL1 0.16 0.04 blup 67 0.06 5.6e-07 6.7 -8.0 1.5e-15 0.71 0.04 0.96 FALSE
34 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SH3YL1 0.20 0.05 blup 67 0.09 9.5e-06 6.7 -5.5 3.4e-08 0.58 0.28 0.54 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma FAM150B 0.07 0.07 lasso 2 0.06 5.8e-07 6.7 -6.8 1.1e-11 0.48 0.71 0.29 FALSE
36 The Cancer Genome Atlas Lung Adenocarcinoma SH3YL1 0.17 0.24 enet 15 0.24 5.8e-28 6.8 -5.9 3.3e-09 0.35 0.67 0.33 FALSE
37 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SH3YL1 0.11 0.10 lasso 5 0.10 4.5e-11 6.8 -5.5 5.0e-08 0.28 0.69 0.31 FALSE
38 The Cancer Genome Atlas Pancreatic Adenocarcinoma SH3YL1 0.21 0.18 lasso 1 0.15 9.6e-07 6.7 -6.7 2.9e-11 0.47 0.68 0.31 FALSE
39 The Cancer Genome Atlas Rectum Adenocarcinoma SH3YL1 0.51 0.29 blup 67 0.38 6.8e-10 6.8 -6.4 1.9e-10 0.21 0.66 0.30 FALSE
40 The Cancer Genome Atlas Soft Tissue Sarcoma SH3YL1 0.07 0.04 enet 9 0.05 1.0e-03 -7.2 7.5 4.9e-14 -0.87 0.04 0.63 FALSE
41 The Cancer Genome Atlas Stomach Adenocarcinoma SH3YL1 0.19 0.21 enet 12 0.23 2.1e-16 6.6 -6.0 2.6e-09 0.33 0.70 0.30 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma SH3YL1 0.54 0.56 lasso 4 0.57 1.1e-67 6.8 -6.4 1.8e-10 0.43 0.64 0.36 FALSE
43 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma SH3YL1 0.16 0.14 lasso 2 0.09 1.8e-03 6.6 -5.7 1.4e-08 0.33 0.13 0.10 FALSE