[Hub]/) : Traits : Standing height : ← →

chr2:8,867,790-10,890,205

Best TWAS P=7.78e-17 · Best GWAS P=7.77e-27 conditioned to 3.8e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADAM17 0.14 0.08 enet 17 0.13 2.2e-15 -6.088 5.5 4.3e-08 0.10 1.00 0.00 FALSE
2 GTEx Brain Cerebellum KLF11 0.30 0.00 lasso 10 0.02 8.7e-02 0.096 6.3 2.5e-10 0.56 0.04 0.42 FALSE
3 GTEx Brain Cortex KLF11 0.42 0.02 enet 38 0.01 1.6e-01 6.410 6.4 1.2e-10 0.52 0.05 0.26 TRUE
4 GTEx Brain Frontal Cortex BA9 ADAM17 0.20 0.14 lasso 5 0.15 7.8e-05 -6.049 6.1 1.3e-09 0.05 0.51 0.04 FALSE
5 GTEx Cells Transformed fibroblasts IAH1 0.09 0.10 lasso 4 0.07 3.7e-06 -5.053 -5.2 2.0e-07 -0.10 0.02 0.98 FALSE
6 GTEx Nerve Tibial ADAM17 0.10 0.02 enet 8 0.01 3.9e-02 -5.053 5.2 1.9e-07 0.11 0.62 0.02 FALSE
7 GTEx Skin Sun Exposed Lower leg CPSF3 0.09 0.07 lasso 3 0.06 7.2e-06 -4.997 -5.2 1.9e-07 -0.10 0.02 0.98 FALSE
8 GTEx Testis CPSF3 0.17 0.03 enet 11 0.05 4.2e-03 -5.434 -5.2 2.6e-07 -0.05 0.10 0.72 FALSE
9 GTEx Thyroid GRHL1 0.15 0.04 enet 30 0.02 1.2e-02 -4.400 8.3 7.8e-17 0.33 0.18 0.21 TRUE
10 NTR Blood ADAM17 0.03 0.03 lasso 8 0.03 2.1e-09 -5.038 5.1 3.0e-07 0.10 1.00 0.00 FALSE
11 NTR Blood IAH1 0.03 0.03 lasso 10 0.04 8.8e-12 -5.043 5.6 1.9e-08 0.09 0.14 0.86 FALSE
12 ROSMAP Brain Pre-frontal Cortex RP11-254F7.2 0.35 0.21 bslmm 562 0.30 1.4e-39 6.251 5.9 3.7e-09 0.58 1.00 0.00 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IAH1 0.03 0.01 blup 35 0.02 1.7e-03 -5.053 -5.7 9.2e-09 -0.07 0.02 0.79 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors ADAM17 0.10 0.14 lasso 2 0.13 3.2e-05 -5.646 -5.8 6.8e-09 -0.12 0.05 0.90 FALSE