[Hub]/) : Traits : Standing height : ← →

chr2:8,867,790-10,890,205

Best TWAS P=7.78e-17 · Best GWAS P=7.77e-27 conditioned to 3.8e-09

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Thyroid	GRHL1	0.15	0.04	enet	30	0.02	1.2e-02	-4.400	8.3	7.8e-17	0.33	0.18	0.21	TRUE
3	GTEx	Brain Cortex	KLF11	0.42	0.02	enet	38	0.01	1.6e-01	6.410	6.4	1.2e-10	0.52	0.05	0.26	TRUE
2	GTEx	Brain Cerebellum	KLF11	0.30	0.00	lasso	10	0.02	8.7e-02	0.096	6.3	2.5e-10	0.56	0.04	0.42	FALSE
4	GTEx	Brain Frontal Cortex BA9	ADAM17	0.20	0.14	lasso	5	0.15	7.8e-05	-6.049	6.1	1.3e-09	0.05	0.51	0.04	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RP11-254F7.2	0.35	0.21	bslmm	562	0.30	1.4e-39	6.251	5.9	3.7e-09	0.58	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ADAM17	0.10	0.14	lasso	2	0.13	3.2e-05	-5.646	-5.8	6.8e-09	-0.12	0.05	0.90	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IAH1	0.03	0.01	blup	35	0.02	1.7e-03	-5.053	-5.7	9.2e-09	-0.07	0.02	0.79	FALSE
11	NTR	Blood	IAH1	0.03	0.03	lasso	10	0.04	8.8e-12	-5.043	5.6	1.9e-08	0.09	0.14	0.86	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ADAM17	0.14	0.08	enet	17	0.13	2.2e-15	-6.088	5.5	4.3e-08	0.10	1.00	0.00	FALSE
6	GTEx	Nerve Tibial	ADAM17	0.10	0.02	enet	8	0.01	3.9e-02	-5.053	5.2	1.9e-07	0.11	0.62	0.02	FALSE
7	GTEx	Skin Sun Exposed Lower leg	CPSF3	0.09	0.07	lasso	3	0.06	7.2e-06	-4.997	-5.2	1.9e-07	-0.10	0.02	0.98	FALSE
5	GTEx	Cells Transformed fibroblasts	IAH1	0.09	0.10	lasso	4	0.07	3.7e-06	-5.053	-5.2	2.0e-07	-0.10	0.02	0.98	FALSE
8	GTEx	Testis	CPSF3	0.17	0.03	enet	11	0.05	4.2e-03	-5.434	-5.2	2.6e-07	-0.05	0.10	0.72	FALSE
10	NTR	Blood	ADAM17	0.03	0.03	lasso	8	0.03	2.1e-09	-5.038	5.1	3.0e-07	0.10	1.00	0.00	FALSE