Best TWAS P=3.7e-12 · Best GWAS P=7.84e-14 conditioned to 0.00584
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C11orf63 | 0.12 | 0.11 | lasso | 5 | 0.10 | 2.3e-08 | 6.7 | -6.8 | 1.2e-11 | 0.80 | 0.43 | 0.57 | FALSE |
| 2 | GTEx | Nerve Tibial | C11orf63 | 0.24 | 0.08 | enet | 18 | 0.22 | 6.2e-16 | 4.0 | -6.8 | 1.1e-11 | 0.60 | 0.34 | 0.66 | FALSE |
| 3 | GTEx | Testis | C11orf63 | 0.32 | 0.14 | lasso | 7 | 0.08 | 3.2e-04 | -6.7 | 7.0 | 3.7e-12 | -0.92 | 0.04 | 0.96 | TRUE |