[Hub]/) : Traits : Standing height :

chr11:125,127,052-127,007,433

Best TWAS P=1.37e-12 · Best GWAS P=5.73e-14 conditioned to 9.02e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ST3GAL4 0.06 0.00 blup 738 0.01 1.3e-02 3.7 6.4 1.3e-10 -0.05 0.36 0.02 TRUE
2 GTEx Adipose Subcutaneous TIRAP 0.18 0.01 enet 38 0.05 4.8e-05 -5.6 7.1 1.4e-12 0.02 0.13 0.39 TRUE
3 GTEx Brain Cortex RP11-712L6.7 0.31 0.02 lasso 6 0.06 9.9e-03 1.3 5.2 2.1e-07 -0.12 0.18 0.16 FALSE
4 GTEx Cells Transformed fibroblasts DCPS 0.09 0.04 lasso 3 0.05 8.8e-05 5.8 -5.5 4.0e-08 -0.03 0.05 0.93 FALSE
5 GTEx Colon Transverse TIRAP 0.22 0.01 enet 28 0.09 4.0e-05 -3.9 5.2 1.7e-07 -0.09 0.20 0.12 FALSE
6 GTEx Esophagus Muscularis CDON 0.19 0.06 lasso 6 0.06 2.5e-04 -4.4 -5.7 9.5e-09 0.63 0.35 0.13 FALSE
7 GTEx Esophagus Muscularis TIRAP 0.14 0.01 enet 24 0.05 4.9e-04 -3.7 5.5 3.0e-08 -0.03 0.47 0.23 FALSE
8 GTEx Esophagus Muscularis RP11-680F20.12 0.14 0.06 lasso 3 0.04 2.2e-03 -4.4 -5.9 3.0e-09 0.63 0.20 0.11 TRUE
9 GTEx Ovary RP11-712L6.7 0.37 0.02 enet 9 0.07 6.9e-03 -5.6 5.9 3.6e-09 -0.06 0.08 0.13 FALSE
10 GTEx Thyroid ST3GAL4 0.18 0.05 lasso 9 0.04 5.7e-04 -5.5 5.5 2.8e-08 -0.32 0.29 0.48 TRUE
11 The Cancer Genome Atlas Breast Invasive Carcinoma DCPS 0.08 0.03 enet 10 0.04 2.9e-09 5.8 -5.3 1.2e-07 -0.03 0.02 0.98 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DCPS 0.06 0.04 enet 10 0.05 1.3e-06 5.8 -5.6 1.7e-08 -0.06 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DCPS 0.04 0.05 lasso 2 0.05 5.9e-06 5.8 -5.3 1.1e-07 -0.04 0.01 0.98 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma DCPS 0.11 0.10 lasso 3 0.09 1.0e-09 5.8 -5.6 1.7e-08 -0.05 0.01 0.99 FALSE
15 The Cancer Genome Atlas Stomach Adenocarcinoma DCPS 0.12 0.02 blup 80 0.05 2.2e-04 6.1 -6.0 2.2e-09 -0.09 0.00 0.99 FALSE