TWAS
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Standing height
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chr12:30,838,951-32,442,681
Best TWAS P=1.06e-08 · Best GWAS P=3.45e-10 conditioned to 0.00535
30.8M
31M
31.2M
31.4M
31.6M
31.8M
32M
32.2M
32.4M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
DENND5B
0.19
0.09
lasso
6
0.15
2.4e-19
-4.5
-5.7
1.1e-08
-0.82
0.15
0.85
TRUE
2
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
C12orf72
0.11
0.00
blup
57
0.02
5.4e-02
2.2
5.5
3.2e-08
0.46
0.01
0.24
FALSE