Best TWAS P=1.06e-08 · Best GWAS P=3.45e-10 conditioned to 0.00535
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DENND5B | 0.19 | 0.09 | lasso | 6 | 0.15 | 2.4e-19 | -4.5 | -5.7 | 1.1e-08 | -0.82 | 0.15 | 0.85 | TRUE |
| 2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | C12orf72 | 0.11 | 0.00 | blup | 57 | 0.02 | 5.4e-02 | 2.2 | 5.5 | 3.2e-08 | 0.46 | 0.01 | 0.24 | FALSE |