Best TWAS P=9.64e-11 · Best GWAS P=6.34e-15 conditioned to 0.0894
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 5.8e-03 | -5.7 | 5.2 | 1.5e-07 | -0.88 | 0.03 | 0.95 | FALSE |
| 2 | NTR | Blood | SLC38A1 | 0.12 | 0.07 | lasso | 6 | 0.08 | 8.4e-24 | 5.5 | -5.2 | 1.7e-07 | 0.02 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SLC38A4 | 0.07 | 0.02 | lasso | 5 | 0.04 | 1.3e-04 | 5.0 | -6.5 | 9.6e-11 | 0.20 | 0.03 | 0.09 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 5.1e-03 | -6.4 | 6.4 | 1.6e-10 | -0.89 | 0.02 | 0.67 | TRUE |