Best TWAS P=2.98e-10 · Best GWAS P=4.24e-12 conditioned to 0.00118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | DOCK9 | 0.09 | 0.02 | lasso | 3 | 0.03 | 1.2e-03 | 4.5 | -5.7 | 1.1e-08 | -0.60 | 0.08 | 0.76 | FALSE |
| 2 | GTEx | Nerve Tibial | DOCK9 | 0.17 | 0.17 | lasso | 1 | 0.16 | 4.1e-11 | 6.3 | -6.3 | 3.0e-10 | -0.77 | 0.11 | 0.89 | TRUE |
| 3 | GTEx | Spleen | DOCK9 | 0.34 | 0.11 | enet | 35 | 0.12 | 5.3e-04 | 4.3 | 5.5 | 4.8e-08 | 0.61 | 0.15 | 0.58 | FALSE |