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chr16:24,042,724-25,620,010

Best TWAS P=2.88e-11 · Best GWAS P=3.62e-13 conditioned to 0.000663

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Heart Atrial Appendage	TNRC6A	0.16	0.00	enet	21	0.01	1.8e-01	6.0	-6.2	6.8e-10	0.25	0.09	0.10	TRUE
2	METSIM	Adipose	SLC5A11	0.23	0.28	lasso	10	0.28	1.6e-42	-5.9	-5.8	6.6e-09	0.69	0.97	0.03	FALSE
3	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC5A11	0.17	0.21	lasso	4	0.21	1.7e-17	-5.7	-6.0	2.0e-09	0.69	0.80	0.20	FALSE
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC5A11	0.12	0.17	enet	9	0.18	1.1e-35	-5.7	-6.7	2.9e-11	0.68	0.80	0.20	TRUE
5	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SLC5A11	0.27	0.24	lasso	6	0.24	4.5e-12	-5.8	-5.8	6.1e-09	0.66	0.80	0.20	FALSE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC5A11	0.27	0.21	lasso	2	0.20	5.2e-12	-5.8	-5.8	7.0e-09	0.69	0.77	0.23	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC5A11	0.13	0.15	enet	8	0.15	6.6e-17	-5.6	-6.4	2.0e-10	0.64	0.81	0.19	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC5A11	0.07	0.07	enet	7	0.06	1.7e-07	-5.6	-6.0	2.4e-09	0.70	0.51	0.49	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC5A11	0.14	0.20	enet	9	0.20	2.2e-23	-5.8	-5.7	1.0e-08	0.67	0.78	0.22	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC5A11	0.06	0.05	lasso	1	0.05	4.9e-06	-5.8	-5.8	8.6e-09	0.69	0.33	0.61	FALSE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SLC5A11	0.30	0.33	lasso	2	0.32	2.8e-14	-5.6	-5.8	9.0e-09	0.65	0.82	0.18	FALSE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SLC5A11	0.54	0.32	lasso	6	0.30	1.8e-12	-5.7	-6.3	2.3e-10	0.70	0.64	0.36	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC5A11	0.26	0.28	lasso	6	0.31	1.0e-32	-5.7	-6.5	8.7e-11	0.66	0.80	0.20	FALSE
14	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC5A11	0.17	0.21	lasso	3	0.18	4.9e-11	-5.6	-5.5	3.0e-08	0.67	0.81	0.19	FALSE
15	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SLC5A11	0.20	0.05	lasso	4	0.04	2.8e-02	-5.8	-5.8	6.7e-09	0.72	0.02	0.47	FALSE
16	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC5A11	0.21	0.10	lasso	5	0.07	2.2e-03	-5.7	-5.5	3.2e-08	0.66	0.20	0.25	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	SLC5A11	0.35	0.44	lasso	4	0.44	4.2e-47	-5.7	-6.0	2.2e-09	0.69	0.84	0.16	FALSE
18	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SLC5A11	0.24	0.15	lasso	3	0.14	1.1e-04	-5.8	-5.8	8.8e-09	0.69	0.16	0.17	FALSE