Best TWAS P=6.02e-08 · Best GWAS P=4.22e-19 conditioned to 6.14e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CYP1B1 | 0.16 | 0.06 | lasso | 5 | 0.07 | 3.8e-06 | 4.6 | 5.3 | 1.4e-07 | -0.07 | 0.64 | 0.02 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CYP1B1 | 0.08 | 0.00 | blup | 584 | 0.02 | 2.2e-03 | -1.3 | 5.4 | 6.0e-08 | 0.06 | 0.12 | 0.02 | TRUE |