Best TWAS P=9.67e-13 · Best GWAS P=7.51e-16 conditioned to 0.000181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | GGA3 | 0.22 | 0.00 | lasso | 4 | 0.00 | 0.3020 | -7.7 | -6.7 | 2.6e-11 | 0.67 | 0.04 | 0.36 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | MRPL38 | 0.22 | 0.01 | enet | 20 | 0.02 | 0.0806 | -4.6 | -5.4 | 5.7e-08 | 0.54 | 0.05 | 0.35 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRB2 | 0.02 | 0.00 | blup | 43 | 0.01 | 0.0046 | -6.2 | -7.1 | 9.7e-13 | 0.89 | 0.01 | 0.82 | TRUE |