Best TWAS P=8.98e-20 · Best GWAS P=6.7e-24 conditioned to 1.74e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ITSN1 | 0.12 | 0.00 | enet | 18 | 0.02 | 5.7e-03 | 2.6 | -5.2 | 1.6e-07 | 0.24 | 0.11 | 0.04 | FALSE |
| 2 | GTEx | Artery Tibial | MRPS6 | 0.10 | 0.04 | enet | 4 | 0.00 | 1.2e-01 | -9.6 | -9.1 | 9.0e-20 | 0.86 | 0.03 | 0.72 | TRUE |
| 3 | NTR | Blood | ITSN1 | 0.07 | 0.06 | lasso | 3 | 0.07 | 5.8e-21 | 4.7 | -5.6 | 2.7e-08 | -0.03 | 1.00 | 0.00 | TRUE |
| 4 | YFS | Blood | ITSN1 | 0.14 | 0.11 | bslmm | 527 | 0.12 | 5.8e-38 | 4.7 | -5.4 | 6.4e-08 | -0.03 | 1.00 | 0.00 | FALSE |