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Standing height
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chr21:34,316,133-36,213,879
Best TWAS P=8.98e-20 · Best GWAS P=6.7e-24 conditioned to 1.74e-06
34.5M
35M
35.5M
36M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
MRPS6
0.10
0.04
enet
4
0.00
1.2e-01
-9.6
-9.1
9.0e-20
0.86
0.03
0.72
TRUE
3
NTR
Blood
ITSN1
0.07
0.06
lasso
3
0.07
5.8e-21
4.7
-5.6
2.7e-08
-0.03
1.00
0.00
TRUE
4
YFS
Blood
ITSN1
0.14
0.11
bslmm
527
0.12
5.8e-38
4.7
-5.4
6.4e-08
-0.03
1.00
0.00
FALSE
1
GTEx
Artery Tibial
ITSN1
0.12
0.00
enet
18
0.02
5.7e-03
2.6
-5.2
1.6e-07
0.24
0.11
0.04
FALSE