TWAS hub - MRPS6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.099	0.0402	0.0059	0.038	NA	0.005	NA	0.000	6.0e-04	NA	1.2e-01	NA	3.4e-01
2	YFS	Blood	0.128	0.0255	0.0000	0.082	0.097	0.121	0.117	0.117	1.8e-25	6.6e-30	1.5e-37	3.9e-36	2.6e-36

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Lung FEV1/FVC ratio	10.3	52.1	90.8	-9.5	3.7
Exposure to tobacco smoke outside home	6.5	8.6	10.2	3.2	-2.7
Heart disease (mother)	6.5	8.0	13.1	1.7	-3.6
Coronary Artery Disease (CAD)	6.4	7.6	8.3	2.6	-2.9
Angina	6.3	8.3	12.2	3.5	-2.1
Angina (self-reported)	6.1	8.0	12.1	3.5	-2.0
Father’s age at death	5.7	7.7	9.6	-3.1	2.4
Townsend deprivation index at recruitment	5.5	7.7	12.0	3.5	-1.8
Heart attack	5.4	6.9	7.4	2.5	-2.7
Myopia	5.4	7.8	9.8	3.1	-2.4
Illnesses of father: Heart disease	5.2	7.2	9.0	2.3	-3.0
Smoking Status	4.7	11.2	19.3	4.4	-1.8
Mother’s age at death	4.6	5.7	11.1	-0.6	3.3
Supplements: Calcium	4.6	5.1	6.9	2.6	-1.8
Heart attack/myocardial infarction (self-reported)	4.6	5.9	6.3	2.5	-2.4
Medication: Co-codamol	4.5	5.2	10.1	3.2	0.6
Height	4.4	85.0	168.7	-13.0	1.1
Alcohol usually taken with meals	4.4	7.1	7.6	-2.8	2.6
Standing height	4.2	41.4	82.8	-9.1	-0.0
Multivitamins +/- minerals	4.1	5.2	10.3	3.2	-0.4
Wheeze or whistling in the chest in last year	4.1	7.3	13.2	3.6	-1.2
Migraine (self-reported)	4.0	4.9	5.5	-2.1	2.4
Smoking status: Current	4.0	6.4	11.8	3.4	-1.0
Diastolic blood pressure, automated reading	4.0	12.5	14.1	3.3	-3.8
Peak expiratory flow (PEF)	3.5	8.0	12.3	-3.5	1.9
Current tobacco smoking	3.3	5.5	8.8	3.0	-1.5
Knee pain experienced in last month	3.3	5.2	5.9	2.4	-2.1
Diabetes (father)	3.2	4.0	7.4	-0.8	2.7
Comparative height size at age 10	3.2	17.8	35.3	-5.9	0.4
Ever smoked	3.2	5.5	7.3	2.7	-1.9
Lung FVC	3.1	16.0	30.9	5.6	1.0
Average weekly fortified wine intake	3.1	3.7	5.0	-2.2	1.5
Past tobacco smoking	3.1	5.6	7.2	-2.7	2.0
Shortness of breath walking on level ground	3.1	3.6	5.1	2.3	-1.5
Pulse wave reflection index	3.0	3.7	5.9	2.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.5	7.9	2.8	2.3
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.2	7.3	2.7	1.1
Forced expiratory volume in 1-second (FEV1)	2.7	9.0	9.7	-3.1	2.9
Vitamin and mineral supplements	2.6	3.6	4.3	-2.1	1.7
Mouth/teeth dental problems	2.6	4.0	7.7	-2.8	0.6
Illnesses of siblings	2.6	3.7	6.3	-2.5	1.0
Mouth/teeth dental problems: Loose teeth	2.6	3.1	5.0	1.1	-2.2
Major Depression (MDD)	2.5	3.1	4.6	1.2	-2.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	7.8	11.7	-3.4	2.0
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.9	3.4	1.5	-1.9
Handedness (chirality/laterality): Left-handed	2.4	2.9	3.5	1.5	-1.9
Fed-up feelings	2.3	4.3	6.7	2.6	-1.4
Financial difficulties in last 2 years	2.3	3.0	5.1	2.3	-1.0
High blood pressure (siblings)	2.2	3.2	6.2	2.5	-0.5
Illnesses of father: None of the above (group 1)	2.2	2.7	3.9	-2.0	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	4.9	2.2	0.8
Bilateral oophorectomy (both ovaries removed)	2.1	2.5	2.7	-1.6	1.5
Suffer from ‘nerves’	2.1	3.2	4.8	1.3	2.2
Long-standing illness, disability or infirmity	2.1	3.2	5.3	2.3	-1.1
Alzheimer’s Disease (in mother)	2.0	2.3	3.4	-1.1	1.8
Lupus	2.0	3.0	6.0	-0.2	-2.4
Supplements: Zinc	2.0	2.1	2.7	1.2	-1.7
Qualifications: CSEs or equivalent	2.0	2.6	2.6	1.6	-1.6
Chronic bronchitis/emphysema (father)	2.0	2.4	4.8	2.2	-0.0
Mouth/teeth dental problems: Bleeding gums	2.0	2.5	3.6	1.9	-1.2
Supplements: Vitamin C	2.0	2.3	4.0	2.0	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	6.8	-1.2	2.6
Maternal smoking around birth	1.9	2.7	4.7	0.9	-2.2
Had menopause	1.9	2.3	3.6	-1.9	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	4.4	2.1	0.5
Smoking status: Previous	1.9	2.8	3.4	1.5	-1.9
HDL Cholesterol	1.8	3.0	5.9	-0.4	-2.4
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.2	4.6	2.2	1.9
Pain all over the body in last month	1.8	2.0	3.1	1.8	0.9
Noisy workplace	1.8	2.3	3.7	1.9	-0.9
Loud music exposure frequency	1.8	2.0	2.0	1.4	1.4
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	4.2	-2.1	1.3
Risk taking	1.8	2.7	4.1	2.0	-1.1
Age started oral contraceptive pill	1.8	2.3	3.6	-1.9	1.0
Average weekly spirits intake	1.7	2.1	3.1	1.1	-1.8
Overall health rating	1.7	3.7	7.0	2.6	-0.6
Ever taken oral contraceptive pill	1.7	1.9	2.3	-1.2	-1.5
Medication: Atorvastatin	1.7	2.2	4.1	0.4	-2.0
Ever had prostate specific antigen (PSA) test	1.7	2.0	2.1	-1.3	1.5
Schizophrenia (2018)	1.6	3.3	6.0	0.8	-2.4
Schizophrenia vs Biploar Disorder	1.6	2.1	3.5	0.8	-1.9
Heel T-Score	1.6	13.0	15.4	3.9	3.3
Number of live births	1.6	2.3	2.9	-1.7	1.3
Pulse wave peak to peak time	1.6	1.8	2.4	-1.5	1.1
High cholesterol (Self-reported)	1.6	2.9	4.5	1.1	-2.1
Waist Hip Ratio (WHR)	1.5	6.7	8.4	-2.3	-2.9
Impedance of arm (right)	1.5	7.1	11.0	-3.3	-1.8
Impedance of arm (left)	1.5	6.7	12.2	-3.5	-1.1
Chronic bronchitis/emphysema (mother)	1.5	1.8	2.8	0.8	-1.7
Pulse rate, automated reading	1.5	4.7	5.4	-2.3	2.0
Mineral and other dietary supplements	1.5	2.1	3.3	-1.8	0.9
Alcohol drinker status: Previous	1.5	1.8	2.4	1.0	-1.6
Age at First Birth	1.4	2.0	2.3	-1.5	1.3
Schizophrenia (2014)	1.4	3.0	6.0	-0.1	-2.5
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	3.4	1.8	-0.5
Arm fat percentage (right)	1.4	5.3	7.1	1.9	-2.7
Illnesses of mother	1.4	1.7	1.8	-1.3	1.3
Medication: Paracetamol	1.4	2.3	4.7	-0.0	2.2
Unable to work because of sickness or disability	1.4	1.8	3.1	1.8	-0.7
Body Mass Index (BMI) (2010)	1.3	1.7	2.1	1.5	1.2
Ever had hysterectomy (womb removed)	1.3	1.5	2.9	-0.2	1.7
Medication: Cholesterol lowering	1.3	2.0	2.9	1.0	-1.7
Medication: Amlodipine	1.3	1.8	2.8	1.7	-0.9
Qualifications: College or University degree	1.3	4.1	5.3	-1.7	-2.3
Number of full sisters	1.3	1.6	3.2	0.3	-1.8
Chest pain or discomfort	1.3	1.9	2.6	1.6	1.1
Ever had bowel cancer screening	1.3	1.5	2.2	0.9	1.5
Average weekly beer plus cider intake	1.3	1.8	2.0	1.4	-1.3
Relative age of first facial hair	1.2	2.5	4.7	-2.2	0.6
Exposure to tobacco smoke at home	1.2	1.3	1.5	1.2	-1.1
Headache pain in last month	1.2	2.0	3.2	-0.9	1.8
Number of children fathered	1.2	1.4	1.7	-1.0	1.3
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.5	1.6	-0.6
Commuting to job workplace: Car/motor vehicle	1.2	1.4	2.8	-1.7	-0.1
Qualifications: nursing, teaching	1.2	1.8	2.3	-1.5	-1.1
Osteoporosis (self-reported)	1.2	1.5	2.9	-0.5	-1.7
Medication: Paracetamol	1.2	1.8	2.5	1.1	1.6
Number of operations (self-reported)	1.2	1.8	2.0	1.4	1.2
Intelligence (Savage-Jansen 2018)	1.1	3.5	4.9	1.4	-2.2
Type 2 Diabetes (T2D) (2012)	1.1	1.3	2.2	0.7	1.5
Blood White Count	1.1	8.3	9.8	3.1	-2.6
Sensitivity / hurt feelings	1.1	1.9	3.7	-0.4	1.9
Frequency of depressed mood in last 2 weeks	1.1	1.6	2.7	1.6	0.7
Hand grip strength (right)	1.1	2.9	5.5	-2.3	0.6
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.2	1.5	0.6
Medication: Ramipril	1.1	1.4	2.8	0.2	-1.7
Eye problems/disorders: None of the above	1.1	1.3	1.9	1.4	-0.8
Emphysema/chronic bronchitis	1.1	1.2	1.7	0.9	-1.3
Eye problems/disorders: Glaucoma	1.1	1.3	2.2	-0.6	1.5
Cholesterol lowering medication	1.1	1.6	3.1	-0.3	-1.8
Qualifications: None of the above	1.0	2.2	4.3	2.1	0.3
Trunk fat-free mass	1.0	5.5	10.9	-3.3	-0.2
Pulse rate	1.0	1.6	2.8	-1.7	0.7
Trunk predicted mass	1.0	5.7	11.4	-3.4	-0.2
Medication: Blood pressure	1.0	1.7	2.4	1.6	-1.0
Arm fat percentage (left)	1.0	4.1	5.8	1.6	-2.4
Commuting to job workplace: Walk	1.0	1.1	1.5	-0.8	-1.2
Mouth/teeth dental problems: Mouth ulcers	1.0	1.7	3.3	1.8	-0.0
Alcohol drinker status: Never	1.0	1.2	1.9	-1.4	-0.7
Irritability	1.0	1.7	2.1	1.5	1.1
Neuroticism (Nagel 2018)	0.9	2.0	4.1	0.1	2.0
Age when periods started (menarche)	0.9	2.2	4.4	-0.2	2.1
Body mass index (BMI)	0.9	4.0	6.1	2.5	-1.3
Neuroticism score	0.9	2.0	3.1	0.9	1.7
Worrier / anxious feelings	0.9	1.8	3.0	-0.7	1.7
Pulse wave Arterial Stiffness index	0.9	1.1	1.7	0.7	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	1.6	1.3	-0.9
Age at last live birth	0.9	1.3	2.5	-1.6	0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.6	-1.2	0.8
Loneliness, isolation	0.9	1.3	2.4	1.6	-0.3
Diabetes diagnosed by doctor	0.9	1.4	1.6	-1.1	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.9	1.4	0.1
Worry (Nagel 2018)	0.8	1.7	3.4	0.1	1.9
Severe depression (siblings)	0.8	0.9	1.1	0.9	1.0
Medication: Atenolol	0.8	1.1	1.4	0.9	1.2
Sitting height	0.8	5.6	10.0	-3.2	-1.1
Impedance of leg (left)	0.8	4.0	4.9	-2.2	1.8
Diabetes (self-reported)	0.8	1.2	2.3	-0.2	1.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	1.1	-1.1	1.0
Tense / ‘highly strung’	0.8	1.3	2.4	0.5	1.6
Hair/balding pattern: Pattern 4	0.8	2.0	3.6	-0.6	1.9
Friendships satisfaction	0.8	1.0	1.9	-1.4	0.0
Number of self-reported non-cancer illnesses	0.8	1.3	2.2	0.7	-1.5
Guilty feelings	0.8	1.2	2.3	-0.3	1.5
Financial situation satisfaction	0.8	1.0	1.6	1.2	-0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	2.1	1.5	-0.2
Illnesses of father: High blood pressure	0.8	1.0	2.0	-1.4	0.3
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	1.7	0.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	2.1	1.4	-0.1
Heart disease (siblings)	0.8	1.0	1.9	0.3	-1.4
Impedance of whole body	0.8	4.0	8.0	-2.8	0.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	3.2	0.1	-1.8
Blood Platelet Count	0.7	8.7	11.0	3.3	-2.5
Respiratory disease	0.7	1.6	2.0	1.4	1.1
Chronotype (morning person)	0.7	1.5	2.5	1.6	0.7
Trunk fat percentage	0.7	2.6	5.3	0.0	-2.3
Relative age voice broke	0.7	1.1	1.5	-1.2	-0.9
Waist circumference	0.7	2.4	4.7	0.2	-2.2
Leg fat percentage (right)	0.7	2.7	3.6	1.9	-1.3
Whole body fat-free mass	0.7	4.2	7.9	-2.8	-0.7
Leg fat-free mass (right)	0.7	3.6	5.0	-2.2	-1.4
Back pain experienced in last month	0.7	1.0	1.7	0.4	-1.3
Whole body water mass	0.7	3.8	7.3	-2.7	-0.6
Leg predicted mass (right)	0.7	3.8	5.1	-2.3	-1.6
Miserableness	0.7	1.2	2.5	-0.1	1.6
Fractured/broken bones in last 5 years	0.7	0.9	1.7	-1.3	0.3
Bipolar Disorder or Schizophrenia	0.6	1.5	3.1	-0.1	-1.7
Ovarian Cancer	0.6	0.8	1.5	-1.2	-0.1
Impedance of leg (right)	0.6	3.1	3.4	-1.7	1.8
Leg fat-free mass (left)	0.6	3.0	4.1	-2.0	-1.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.3	1.1	-0.2
Leg predicted mass (left)	0.6	3.2	4.4	-2.1	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.0	1.4	0.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.7	-1.3	-0.9
Asthma	0.6	1.2	1.8	1.4	0.8
Depression (self-reported)	0.6	0.7	0.9	0.9	0.7
Glaucoma (self-reported)	0.6	0.7	1.3	-0.1	1.2
Body fat percentage	0.6	2.2	3.8	0.7	-2.0
Worry too long after embarrassment	0.6	0.9	1.5	-0.6	1.2
Mood swings	0.6	1.0	1.4	1.2	0.8
Osteoarthritis (self-reported)	0.6	0.7	1.4	0.3	1.2
Medication: Blood pressure	0.6	1.1	1.7	-0.6	-1.3
Basal metabolic rate	0.6	3.4	5.9	-2.4	-0.9
Leg fat percentage (left)	0.6	2.2	2.7	1.6	-1.3
Basal cell carcinoma (self-reported)	0.6	0.7	1.4	1.2	-0.2
Depression (Nagel 2018)	0.5	0.8	1.0	1.0	0.8
Alzheimer’s Disease (in father)	0.5	0.6	0.6	0.8	-0.7
Blood Red Count	0.5	4.4	8.6	2.9	0.5
Allergy or Eczema	0.5	1.3	2.3	-0.5	1.5
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.0	-1.0	1.0
Hand grip strength (left)	0.5	1.2	2.4	-1.6	0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	0.7	0.7	0.8
Trunk fat mass	0.5	2.3	4.0	-0.8	-2.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.8	0.7	-0.9
Allergy	0.5	1.1	1.5	-1.2	-0.8
Weight	0.5	2.2	2.7	-1.6	-1.3
Mouth/teeth dental problems: Dentures	0.5	0.8	1.3	1.1	0.7
Arm fat mass (right)	0.5	2.3	4.4	0.2	-2.1
Breastfed as a baby	0.5	0.6	1.0	-1.0	-0.5
Blood clot in the leg (DVT)	0.5	0.7	1.3	1.1	0.4
Gout (self-reported)	0.5	0.8	1.3	0.5	-1.1
Arm predicted mass (right)	0.5	2.8	5.6	-2.4	0.2
Leg pain on walking	0.5	0.6	1.1	1.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	1.3	-1.0	-1.1
Asthma (self-reported)	0.5	1.1	1.3	1.1	0.9
Commuting to job workplace: Public transport	0.5	0.6	1.1	0.4	1.1
Arm fat-free mass (left)	0.5	2.6	5.1	-2.3	-0.4
Bipolar Disorder (2018)	0.4	0.7	1.3	-1.1	0.2
Alzheimer’s Disease (including proxy)	0.4	0.5	0.8	-0.6	0.9
Prostate Cancer	0.4	0.6	1.2	-0.1	-1.1
Fasting Glucose	0.4	0.4	0.5	0.6	-0.7
LDL Cholesterol	0.4	0.6	1.1	-0.4	1.1
Pack years adult smoking proportion	0.4	0.6	0.7	-0.7	-0.8
Hayfever, allergic rhinitis or eczema	0.4	1.0	1.7	-0.4	1.3
Nervous feelings	0.4	0.7	1.3	0.4	1.1
Forced vital capacity (FVC)	0.4	1.6	3.1	-0.4	1.8
Time employed in main current job	0.4	0.4	0.7	-0.3	0.9
Birth weight of first child	0.4	0.8	1.4	-0.5	1.2
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.8	-0.1	-0.9
Arm fat-free mass (right)	0.4	2.2	4.2	-2.1	0.3
Whole body fat mass	0.4	1.5	2.9	-0.4	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.6	-0.8	-0.6
Medication for cholesterol	0.4	0.6	0.6	0.8	0.8
Breast cancer (self-reported)	0.4	0.4	0.9	0.1	-0.9
Arm fat mass (left)	0.4	1.8	3.5	0.2	-1.9
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.7	0.8	-0.5
Commuting to job workplace: Cycle	0.4	0.5	0.9	0.2	-0.9
Pain experienced in last month	0.4	0.6	0.8	-0.6	0.9
Arm predicted mass (left)	0.4	2.2	4.4	-2.1	-0.1
Neuroticism (2016)	0.3	0.5	1.0	-0.1	-1.0
BMI	0.3	1.5	2.0	1.4	-1.0
Systolic Blood Pressure	0.3	1.7	2.0	-1.2	-1.4
Hypothyroidism (self reported)	0.3	0.6	1.0	-1.0	0.6
Neuroticism	0.3	0.6	1.2	0.1	1.1
Number of treatments/medications taken	0.3	0.6	0.6	0.8	-0.7
Number of incorrect matches in round	0.3	0.5	1.0	-0.2	1.0
Hair/balding pattern: Pattern 2	0.3	0.4	0.6	0.5	-0.8
Medication: Simvastatin	0.3	0.4	0.4	0.6	-0.6
Fluid intelligence score	0.3	0.6	1.2	-0.2	-1.1
Hip circumference	0.3	1.5	2.0	0.9	-1.4
Alcohol intake versus 10 years previously	0.3	0.4	0.6	0.5	-0.8
Falls in the last year	0.3	0.4	0.6	0.4	-0.8
Happiness	0.3	0.4	0.8	-0.0	0.9
Prospective memory result	0.3	0.4	0.6	-0.4	0.7
Medication: Ibuprofen	0.3	0.4	0.4	-0.6	0.7
Medication: Omeprazole	0.3	0.4	0.8	-0.0	-0.9
Medication: Seretide 50 evohaler	0.3	0.4	0.6	0.4	-0.8
Eye problems/disorders: Cataract	0.3	0.4	0.7	-0.8	-0.2
Medication: Gliclazide	0.3	0.4	0.7	0.3	0.8
Wears glasses or contact lenses	0.3	0.4	0.5	-0.5	0.7
Pack years of smoking	0.3	0.5	0.6	-0.6	-0.8
Ulcerative Colitis (UC)	0.2	0.4	0.5	-0.7	0.5
Breast Cancer	0.2	0.4	0.7	0.4	0.8
Crohns Disease (2012)	0.2	0.3	0.5	-0.7	-0.2
HbA1C	0.2	0.2	0.3	0.5	0.5
Triglycerides	0.2	0.3	0.4	0.7	-0.4
Cardiovascular Disease	0.2	0.7	0.8	-0.7	-0.9
Hearing difficulty/problems: Yes	0.2	0.3	0.6	0.8	-0.2
Systolic blood pressure, automated reading	0.2	0.6	0.9	-0.5	-1.0
Medication for hormone replacement therapy	0.2	0.2	0.3	-0.5	0.4
Diabetes (mother)	0.2	0.2	0.5	0.7	0.2
High blood pressure	0.2	0.6	0.9	-1.0	-0.5
Stomach or abdominal pain in last month	0.2	0.2	0.2	0.4	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.3	-0.5	0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	-0.7	0.1
Birth weight	0.2	0.5	1.0	0.1	1.0
Health satisfaction	0.2	0.2	0.4	-0.6	0.3
Medication: Allopurinol	0.2	0.3	0.4	0.7	-0.3
Leg fat mass (right)	0.2	0.9	1.5	0.6	-1.2
Had major operations	0.2	0.3	0.5	0.1	-0.7
Hypertension (Self-reported)	0.2	0.6	1.0	-1.0	-0.4
Average weekly red wine intake	0.2	0.3	0.3	0.6	-0.5
Average weekly champagne plus white wine intake	0.2	0.3	0.5	-0.7	0.4
Medication: Lisinopril	0.2	0.2	0.4	0.7	-0.1
Vascular/heart problems diagnosed by doctor	0.2	0.4	0.9	0.2	0.9
Leg fat mass (left)	0.2	0.9	1.5	0.5	-1.2
Depressed Affect (Nagel 2018)	0.1	0.3	0.3	0.6	0.5
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.6	-0.1
Reaction Time	0.1	0.1	0.2	-0.2	-0.4
Bipolar Disorder (2011)	0.1	0.1	0.2	0.4	-0.3
Rheumatoid Arthritis	0.1	0.1	0.2	-0.4	0.1
Blood Eosinophil Count	0.1	1.0	1.9	0.2	-1.4
Hair Pigment	0.1	3.0	5.4	0.8	-2.3
Tanning	0.1	0.8	1.4	1.2	0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.3	0.5	0.1
Medication: Metformin	0.1	0.1	0.2	-0.2	0.5
Taking other prescription medications	0.1	0.1	0.2	-0.4	0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.3	0.1	-0.5
Supplements: Glucosamine	0.1	0.1	0.2	0.5	-0.2
Medication: Levothyroxine sodium	0.1	0.1	0.1	-0.3	-0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.3	0.1	0.6
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.6	0.2
Medication: Lansoprazole	0.1	0.1	0.1	0.2	-0.3
Lung cancer (father)	0.1	0.2	0.3	0.2	0.6
Length of working week for main job	0.1	0.1	0.2	0.4	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	0.7	-0.6	0.8
Comparative body size at age 10	0.1	0.2	0.4	-0.2	0.6
Number of full brothers	0.1	0.2	0.3	0.6	0.0
Age at first live birth	0.1	0.2	0.2	-0.4	0.4
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	-0.1	-0.6
Alcohol intake frequency.	0.1	0.2	0.3	0.2	-0.6
Family relationship satisfaction	0.1	0.1	0.2	0.2	-0.4
Medication: Aspirin	0.1	0.1	0.1	0.3	0.3
Hearing aid user	0.1	0.2	0.3	0.5	0.2
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.1	-0.3
Medication: Bendroflumethiazide	0.1	0.1	0.2	0.5	0.2
Ever depressed for a whole week	0.1	0.2	0.3	0.5	-0.2
Crohns Disease (2017)	0.0	0.1	0.1	0.3	-0.4
Mean Putamen Volume	0.0	0.0	0.0	-0.0	-0.1
Primary Biliary Cirrhosis	0.0	0.0	0.1	0.3	-0.0
Ulcerative Colitis	0.0	0.1	0.1	-0.3	-0.2
High blood pressure (mother)	0.0	0.1	0.1	0.4	-0.0
Had other major operations	0.0	0.0	0.0	0.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.0	0.0	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.1	0.0	0.2
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.1	-0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.1	-0.3	-0.2
Neck or shoulder pain in last month	0.0	0.0	0.0	0.2	-0.1
Mean time to correctly identify matches	0.0	0.0	0.1	-0.2	0.2
Medication: Aspirin	0.0	0.0	0.0	0.1	0.0
Illnesses of siblings: Diabetes	0.0	0.1	0.1	0.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	-0.1	-0.0

Hub : Genes

MRPS6

Models

Trait associations