[Hub]/) : Traits : Standing height :

chr21:36,744,868-41,512,399

Best TWAS P=5.24e-16 · Best GWAS P=8.33e-32 conditioned to 1.23e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CBR1 0.25 0.12 enet 29 0.20 9.5e-24 -3.8 -5.3 9.5e-08 -0.05 0.24 0.54 TRUE
2 GTEx Adipose Subcutaneous WRB 0.44 0.52 lasso 5 0.55 7.7e-53 5.6 5.6 2.4e-08 -0.02 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous PIGP 0.39 0.37 enet 26 0.49 2.1e-45 4.3 5.2 2.2e-07 0.01 0.09 0.82 TRUE
4 GTEx Adipose Visceral Omentum WRB 0.53 0.44 lasso 11 0.42 1.5e-23 5.6 5.5 3.7e-08 -0.01 0.01 0.99 FALSE
5 GTEx Artery Aorta WRB 0.24 0.31 lasso 3 0.30 4.2e-17 5.6 5.5 3.1e-08 -0.02 0.01 0.99 FALSE
6 GTEx Artery Coronary WRB 0.56 0.50 lasso 3 0.50 2.1e-19 5.5 5.5 2.9e-08 -0.02 0.01 0.99 FALSE
7 GTEx Artery Tibial WRB 0.57 0.58 enet 19 0.59 4.8e-56 5.6 5.4 5.7e-08 -0.02 0.01 0.99 FALSE
8 GTEx Brain Cerebellar Hemisphere LCA5L 0.65 0.53 lasso 7 0.49 1.8e-14 5.6 5.5 3.3e-08 -0.02 0.01 0.99 FALSE
9 GTEx Brain Cerebellum LCA5L 0.72 0.53 lasso 12 0.53 2.0e-18 5.6 5.5 3.2e-08 -0.01 0.01 0.99 FALSE
10 GTEx Breast Mammary Tissue WRB 0.38 0.38 lasso 4 0.37 4.2e-20 5.5 5.5 4.5e-08 -0.01 0.01 0.99 FALSE
11 GTEx Cells Transformed fibroblasts WRB 0.43 0.46 enet 23 0.48 4.0e-40 5.6 5.4 5.8e-08 -0.02 0.01 0.99 FALSE
12 GTEx Colon Sigmoid WRB 0.38 0.21 lasso 7 0.24 4.3e-09 5.6 5.5 4.8e-08 -0.02 0.01 0.99 FALSE
13 GTEx Colon Transverse WRB 0.27 0.19 lasso 5 0.17 2.1e-08 5.6 5.8 6.8e-09 -0.01 0.01 0.99 FALSE
14 GTEx Colon Transverse BRWD1-IT2 0.28 0.01 enet 41 0.04 8.4e-03 -4.7 6.2 5.1e-10 -0.07 0.13 0.22 TRUE
15 GTEx Esophagus Gastroesophageal Junction WRB 0.42 0.44 lasso 5 0.43 4.3e-17 5.6 5.6 2.6e-08 -0.02 0.01 0.99 FALSE
16 GTEx Esophagus Mucosa WRB 0.29 0.33 lasso 2 0.32 3.4e-22 5.6 5.6 2.6e-08 -0.01 0.01 0.99 FALSE
17 GTEx Esophagus Muscularis WRB 0.34 0.38 lasso 5 0.39 7.1e-25 5.6 5.6 2.4e-08 -0.02 0.01 0.99 FALSE
18 GTEx Lung WRB 0.29 0.22 enet 13 0.24 1.9e-18 5.6 5.2 2.1e-07 -0.04 0.01 0.99 FALSE
19 GTEx Nerve Tibial WRB 0.47 0.43 lasso 4 0.43 3.5e-33 5.6 5.7 1.2e-08 -0.02 0.01 0.99 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic WRB 0.35 0.31 lasso 3 0.31 1.4e-17 5.6 5.6 2.4e-08 -0.01 0.01 0.99 FALSE
21 GTEx Skin Sun Exposed Lower leg WRB 0.34 0.37 lasso 5 0.36 1.8e-31 5.6 5.6 2.3e-08 -0.02 0.01 0.99 FALSE
22 GTEx Uterus LCA5L 0.55 0.27 enet 10 0.26 4.9e-06 5.6 5.5 4.0e-08 -0.02 0.01 0.99 FALSE
23 GTEx Uterus WRB 0.39 0.28 lasso 4 0.24 1.4e-05 5.6 5.6 2.3e-08 -0.02 0.01 0.98 FALSE
24 GTEx Whole Blood WRB 0.22 0.12 lasso 7 0.11 3.0e-10 5.4 5.8 5.9e-09 -0.01 0.01 0.99 FALSE
25 METSIM Adipose KCNJ15 0.05 0.03 lasso 5 0.02 6.8e-04 -7.5 8.1 7.3e-16 -0.65 0.77 0.17 FALSE
26 METSIM Adipose WRB 0.18 0.27 lasso 7 0.27 5.7e-40 5.3 5.5 2.9e-08 -0.01 0.01 0.99 FALSE
27 NTR Blood KCNJ15 0.06 0.09 lasso 4 0.09 7.0e-27 -7.3 7.4 1.3e-13 -0.65 1.00 0.00 FALSE
28 NTR Blood LCA5L 0.04 0.04 bslmm 718 0.03 4.5e-11 5.6 5.7 1.0e-08 -0.01 0.01 0.99 FALSE
29 NTR Blood WRB 0.07 0.07 enet 13 0.08 5.9e-24 5.3 5.7 1.5e-08 -0.02 0.01 0.99 FALSE
30 YFS Blood KCNJ15 0.22 0.29 enet 19 0.30 3.9e-100 -7.6 7.8 7.7e-15 -0.66 1.00 0.00 FALSE
31 YFS Blood PSMG1 0.06 0.06 lasso 4 0.07 1.1e-21 -4.7 -5.3 1.2e-07 -0.01 0.40 0.60 FALSE
32 YFS Blood WRB 0.20 0.29 enet 18 0.29 8.4e-95 5.6 5.5 5.0e-08 -0.02 0.01 0.99 FALSE
33 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma WRB 0.05 0.07 lasso 2 0.06 5.7e-04 5.6 5.6 2.3e-08 -0.02 0.01 0.98 FALSE
34 The Cancer Genome Atlas Colon Adenocarcinoma CBR1 0.45 0.09 lasso 5 0.22 5.1e-13 2.4 -5.1 2.9e-07 -0.02 0.02 0.55 FALSE
35 The Cancer Genome Atlas Colon Adenocarcinoma WRB 0.06 0.07 lasso 1 0.05 1.1e-03 5.4 5.4 6.7e-08 -0.03 0.01 0.92 FALSE
36 The Cancer Genome Atlas Esophageal Carcinoma WRB 0.16 0.12 lasso 2 0.12 1.1e-04 5.6 5.6 2.3e-08 -0.01 0.01 0.93 FALSE
37 The Cancer Genome Atlas Glioblastoma Multiforme HMGN1 0.19 0.04 blup 43 0.08 2.1e-03 4.8 -5.6 2.1e-08 0.01 0.02 0.71 FALSE
38 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma WRB 0.11 0.12 enet 6 0.12 2.5e-07 5.6 5.5 3.2e-08 -0.02 0.01 0.99 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma WRB 0.17 0.32 enet 11 0.31 4.6e-36 5.6 5.4 7.0e-08 -0.01 0.00 1.00 FALSE
40 The Cancer Genome Atlas Lung Adenocarcinoma WRB 0.07 0.07 lasso 3 0.06 7.7e-08 5.6 5.6 2.8e-08 -0.02 0.00 1.00 FALSE
41 The Cancer Genome Atlas Lung Squamous Cell Carcinoma WRB 0.05 0.04 lasso 7 0.06 3.1e-07 5.5 6.5 7.4e-11 -0.01 0.01 0.99 TRUE
42 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma WRB 0.08 0.07 blup 48 0.06 7.6e-05 5.6 6.1 9.8e-10 -0.03 0.01 0.99 FALSE
43 The Cancer Genome Atlas Prostate Adenocarcinoma WRB 0.08 0.08 lasso 4 0.08 6.1e-09 5.6 5.8 7.5e-09 -0.02 0.01 0.99 FALSE
44 The Cancer Genome Atlas Skin Cutaneous Melanoma WRB 0.12 0.06 blup 48 0.10 1.2e-03 3.0 5.1 2.8e-07 0.00 0.01 0.68 TRUE
45 The Cancer Genome Atlas Stomach Adenocarcinoma WRB 0.09 0.08 lasso 2 0.07 8.6e-06 5.6 5.6 1.6e-08 -0.02 0.00 0.99 FALSE
46 The Cancer Genome Atlas Testicular Germ Cell Tumors DSCR10 0.07 0.03 blup 35 0.06 3.0e-03 7.0 -8.1 5.2e-16 0.67 0.02 0.66 TRUE
47 The Cancer Genome Atlas Thyroid Carcinoma CBR1 0.46 0.13 enet 18 0.20 3.5e-19 2.4 -5.2 1.9e-07 -0.03 0.05 0.02 FALSE
48 The Cancer Genome Atlas Thyroid Carcinoma KCNJ15 0.09 0.05 blup 66 0.05 1.3e-05 3.6 5.3 1.5e-07 -0.38 0.16 0.14 FALSE
49 The Cancer Genome Atlas Thyroid Carcinoma WRB 0.13 0.25 lasso 8 0.26 4.2e-25 5.6 5.5 4.5e-08 -0.02 0.00 1.00 FALSE