Best TWAS P=3.12e-09 · Best GWAS P=4.73e-08 conditioned to 0.00515
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | RAB3GAP1 | 0.04 | 0.00 | enet | 8 | 0.00 | 2.3e-01 | -4.9 | 5.3 | 1.4e-07 | -0.74 | 0.07 | 0.53 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RAB3GAP1 | 0.02 | 0.01 | blup | 74 | 0.02 | 6.5e-03 | -5.1 | 5.3 | 1.5e-07 | -0.66 | 0.02 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZRANB3 | 0.12 | 0.04 | blup | 118 | 0.05 | 6.6e-06 | -5.1 | 5.2 | 1.6e-07 | -0.74 | 0.07 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | ZRANB3 | 0.04 | 0.05 | blup | 118 | 0.05 | 5.8e-04 | -5.0 | 5.3 | 1.1e-07 | -0.77 | 0.07 | 0.82 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZRANB3 | 0.02 | 0.02 | lasso | 11 | 0.03 | 5.4e-04 | -5.1 | 5.2 | 1.6e-07 | -0.81 | 0.08 | 0.88 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZRANB3 | 0.31 | 0.08 | enet | 8 | 0.11 | 2.8e-11 | -5.5 | 5.1 | 3.0e-07 | -0.92 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | R3HDM1 | 0.04 | 0.00 | enet | 6 | 0.03 | 4.9e-04 | -5.0 | -5.9 | 3.1e-09 | 0.52 | 0.01 | 0.49 | TRUE |