TWAS hub - R3HDM1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.083	0.051	0.0055	-0.004	NA	0.002	NA	0.005	0.69	NA	0.24000	NA	0.1400
2	TCGA	Thyroid Carcinoma	0.045	0.028	0.0021	0.004	0.019	0.031	NA	0.024	0.13	0.0048	0.00049	NA	0.0018

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Cholesterol lowering	5.8	9.0	11.9	3.5	2.5
Forced expiratory volume in 1-second (FEV1), predicted	4.9	10.2	10.8	-3.3	-3.1
Unable to work because of sickness or disability	4.6	6.0	7.1	2.7	2.2
Ever had stillbirth, spontaneous miscarriage or termination	4.1	4.4	6.0	-1.7	-2.4
Mother’s age at death	4.0	5.0	5.6	2.4	2.1
Mouth/teeth dental problems	3.8	5.9	11.8	3.4	0.2
Chronotype (morning person)	3.7	8.6	11.6	2.4	3.4
High cholesterol (Self-reported)	3.7	6.5	11.0	3.3	1.4
Tinnitus: Yes, but not now, but have in the past	3.5	3.8	6.5	-2.6	-1.0
Ever highly irritable/argumentative for 2 days	3.3	4.0	4.2	-1.9	-2.1
Medication: Atorvastatin	3.1	3.8	4.6	2.2	1.7
Had other major operations	3.0	3.7	4.1	1.8	2.0
Average weekly beer plus cider intake	2.8	4.0	7.3	2.7	0.9
Alzheimer’s Disease (in mother)	2.7	3.2	6.0	-0.6	-2.5
Standing height	2.5	24.7	35.0	-3.8	-5.9
Heart disease (mother)	2.5	3.0	3.2	1.7	1.8
Family relationship satisfaction	2.5	3.0	4.2	-2.0	-1.4
Medication: Paracetamol	2.5	3.8	4.2	-1.9	-2.0
Diabetes (father)	2.3	2.9	4.7	2.2	1.0
Migraine (self-reported)	2.3	2.9	5.3	-2.3	-0.7
Pulse wave peak to peak time	2.2	2.5	3.8	-1.1	-1.9
Osteoarthritis (self-reported)	2.2	2.9	4.7	1.0	2.2
Ever had hysterectomy (womb removed)	2.0	2.3	2.7	-1.3	-1.7
Medication for cholesterol, blood pressure or diabetes	2.0	3.4	3.7	-1.9	-1.7
Risk taking	2.0	3.0	4.4	-2.1	-1.3
LDL Cholesterol	1.9	3.1	4.7	-1.2	-2.2
Supplements: Zinc	1.9	2.0	3.3	-0.9	-1.8
Forced vital capacity (FVC)	1.9	7.4	14.1	-0.9	-3.8
Illnesses of mother	1.9	2.3	4.1	-2.0	-0.8
Alzheimer’s Disease (in father)	1.8	1.9	2.2	1.5	1.3
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	5.3	-2.3	-0.6
Bipolar Disorder (2018)	1.7	2.6	4.0	1.1	2.0
Fasting Glucose	1.7	2.0	2.1	1.4	1.5
Height	1.7	32.0	49.3	-3.8	-7.0
Sensitivity / hurt feelings	1.7	2.9	4.2	1.3	2.1
Frequency of depressed mood in last 2 weeks	1.7	2.3	3.6	-1.9	-1.0
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	10.3	-0.9	-3.2
Age at First Birth	1.6	2.4	3.8	1.9	-1.0
Hand grip strength (left)	1.6	4.2	8.0	-0.7	-2.8
Time employed in main current job	1.6	1.8	2.9	1.7	-0.9
Gout (self-reported)	1.6	2.3	4.3	2.1	0.5
Number of full brothers	1.6	2.0	3.2	1.8	0.9
Comparative height size at age 10	1.6	8.5	15.1	-1.4	-3.9
Lupus	1.5	2.2	3.3	-1.8	-1.1
Medication: Ramipril	1.5	1.9	3.0	0.9	1.7
Number of live births	1.5	2.2	3.0	-1.7	-1.2
Mouth/teeth dental problems: Dentures	1.5	2.5	5.0	-2.2	-0.0
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.8	-1.9	-0.2
Angina	1.4	1.8	2.3	1.5	1.2
Forced vital capacity (FVC), Best measure	1.4	5.0	9.7	-0.6	-3.1
Diastolic blood pressure, automated reading	1.4	4.4	7.6	1.1	2.8
Townsend deprivation index at recruitment	1.3	1.9	2.0	1.3	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	1.9	1.2	1.4
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	4.3	2.1	-0.1
Angina (self-reported)	1.3	1.7	2.2	1.5	1.1
Loneliness, isolation	1.3	1.8	3.5	0.1	1.9
Illnesses of father: None of the above (group 1)	1.3	1.6	2.4	-0.9	-1.6
HbA1C	1.2	1.4	2.5	-0.4	-1.6
Triglycerides	1.2	2.0	3.9	2.0	0.4
Systolic blood pressure, automated reading	1.2	3.6	5.5	1.3	2.3
Medication: Co-codamol	1.2	1.4	2.4	-1.6	-0.7
Serious illness, injury or assault to yourself	1.2	1.4	2.6	-0.5	1.6
Medication: Atenolol	1.2	1.5	2.2	-0.8	-1.5
Had menopause	1.2	1.6	3.0	0.3	1.7
Depression (self-reported)	1.2	1.5	2.4	-0.7	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	7.3	-0.6	-2.7
Pulse wave Arterial Stiffness index	1.2	1.4	2.0	0.8	1.4
Birth weight of first child	1.2	2.2	3.0	-1.2	-1.7
Blood clot in the leg (DVT)	1.2	1.5	3.0	-1.7	-0.1
Exposure to tobacco smoke outside home	1.2	1.7	2.3	1.0	1.5
Medication: Ibuprofen	1.2	1.4	2.8	0.2	-1.7
Pulse rate, automated reading	1.2	3.8	6.8	0.9	2.6
Guilty feelings	1.2	1.7	2.0	-1.2	-1.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	3.1	-1.8	-0.2
Verbal and Numeric Reasoning (VNR)	1.1	2.7	4.3	2.1	1.0
Medication: Metformin	1.1	1.6	2.5	1.6	0.9
Noisy workplace	1.1	1.3	2.2	-1.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	2.6	-0.4	-1.6
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.7	0.0	-1.6
Heart disease (siblings)	1.1	1.3	1.5	1.2	1.1
Medication for hormone replacement therapy	1.0	1.2	2.3	0.0	1.5
Average weekly fortified wine intake	1.0	1.2	2.2	-0.4	-1.5
Maternal smoking around birth	1.0	1.4	1.9	-1.0	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	2.4	-1.0	-1.6
Medication: Paracetamol	1.0	1.7	2.8	-0.7	-1.7
Number of children fathered	1.0	1.1	1.7	-0.7	-1.3
Handedness (chirality/laterality): Left-handed	1.0	1.1	1.6	1.3	0.8
Commuting to job workplace: Walk	1.0	1.0	1.1	1.0	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.9	-1.4	-0.6
Commuting to job workplace: Public transport	1.0	1.2	2.4	0.2	-1.6
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.1	-0.5	-1.4
Coronary Artery Disease (CAD)	0.9	1.1	2.2	-1.5	0.2
Smoking Status	0.9	2.3	2.7	-1.3	-1.7
Cardiovascular Disease	0.9	3.0	4.7	2.2	1.1
Taking other prescription medications	0.9	1.3	2.6	0.1	1.6
Qualifications: CSEs or equivalent	0.9	1.1	2.0	-1.4	-0.5
Sitting height	0.9	6.4	7.4	-2.3	-2.7
Alcohol usually taken with meals	0.9	1.5	2.9	1.7	0.4
Financial difficulties in last 2 years	0.9	1.2	2.4	-0.2	-1.6
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.6	-0.9	-1.2
Illnesses of siblings	0.9	1.2	1.8	-0.8	-1.4
Weight	0.9	4.5	8.4	-2.9	-0.7
Trunk fat-free mass	0.9	5.1	5.6	-2.2	-2.4
Trunk predicted mass	0.9	5.1	5.7	-2.1	-2.4
Glaucoma (self-reported)	0.9	1.0	1.6	-1.2	-0.7
Leg fat percentage (right)	0.9	3.1	4.8	-1.2	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.1	-1.5	-0.5
Neck or shoulder pain in last month	0.9	1.3	2.5	0.2	1.6
Knee pain experienced in last month	0.9	1.4	2.4	-1.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	3.8	-0.1	-1.9
Basal metabolic rate	0.9	4.9	6.4	-2.5	-1.8
Leg fat percentage (left)	0.9	3.3	5.4	-1.1	2.3
Arm fat-free mass (left)	0.9	4.8	6.9	-2.6	-1.6
Arm predicted mass (left)	0.9	4.6	6.5	-2.5	-1.7
Rheumatoid Arthritis	0.8	1.2	2.3	-1.5	-0.0
BMI	0.8	4.4	8.9	-0.0	3.0
Respiratory disease	0.8	1.7	2.1	-1.4	-1.1
Relative age of first facial hair	0.8	1.7	3.2	-0.5	-1.8
Diabetes (mother)	0.8	1.1	1.2	1.0	1.1
Hand grip strength (right)	0.8	2.1	4.0	-0.6	-2.0
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.3	-0.8	-1.1
Falls in the last year	0.8	1.1	2.1	0.1	-1.5
Hair/balding pattern: Pattern 3	0.8	1.2	1.6	1.3	0.9
Medication: Lansoprazole	0.8	0.9	1.7	-0.1	1.3
Breastfed as a baby	0.8	1.0	2.0	1.4	-0.1
Shortness of breath walking on level ground	0.8	0.9	1.8	-1.3	-0.3
Arm predicted mass (right)	0.8	4.1	5.7	-2.4	-1.6
Illnesses of siblings: Diabetes	0.8	1.0	2.0	1.4	0.0
Whole body fat-free mass	0.8	4.5	5.2	-2.3	-2.0
Whole body water mass	0.8	4.8	5.5	-2.3	-2.0
Prostate Cancer	0.7	1.0	1.9	-0.0	1.4
Crohns Disease (2012)	0.7	1.1	2.0	-0.4	-1.4
Primary Biliary Cirrhosis	0.7	1.0	1.8	1.3	-0.5
Ulcerative Colitis	0.7	1.0	1.9	-0.3	-1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.8	0.1	1.3
Multivitamins +/- minerals	0.7	0.9	1.4	1.2	-0.6
Body mass index (BMI)	0.7	3.1	4.8	-1.2	2.2
Qualifications: None of the above	0.7	1.5	3.0	0.0	1.7
Length of working week for main job	0.7	0.8	1.6	0.1	-1.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.4	-1.2	0.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.0	0.9	1.0
Bipolar Disorder or Schizophrenia	0.6	1.3	2.6	-0.3	1.6
Systolic Blood Pressure	0.6	3.2	4.1	2.0	1.5
Lung FVC	0.6	3.0	5.3	2.3	-0.8
Average weekly spirits intake	0.6	0.7	0.9	0.8	0.9
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	0.7	-0.8	0.7
Leg fat-free mass (left)	0.6	3.0	4.1	-2.0	-1.3
Chronic bronchitis/emphysema (father)	0.6	0.8	1.5	-1.2	0.0
High blood pressure (mother)	0.6	0.9	0.9	-0.9	-0.9
Arm fat percentage (right)	0.6	2.4	3.3	-1.2	1.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	0.8	-0.8	-0.9
Headache pain in last month	0.6	1.1	2.1	0.3	1.4
High blood pressure (siblings)	0.6	0.8	1.7	0.1	1.3
Body fat percentage	0.6	2.6	2.8	-1.5	1.7
Arm fat-free mass (right)	0.6	3.1	4.2	-2.1	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.6	1.2	1.1	0.3
Qualifications: College or University degree	0.6	1.8	3.3	-0.5	-1.8
Medication for pain relief, constipation, heartburn	0.6	1.0	1.5	0.7	1.2
Leg fat mass (right)	0.6	2.3	2.9	-1.7	1.3
Alcohol intake frequency.	0.6	1.3	1.6	-1.3	1.0
Arm fat percentage (left)	0.6	2.5	4.0	-1.1	2.0
Breast cancer (self-reported)	0.6	0.7	1.5	0.1	1.2
Hearing aid user	0.6	0.6	1.3	-0.1	1.1
Illnesses of father: High blood pressure	0.6	0.7	1.0	0.7	1.0
Cholesterol lowering medication	0.6	0.9	0.9	0.9	0.9
Supplements: Calcium	0.6	0.7	1.1	1.1	-0.5
Basal cell carcinoma (self-reported)	0.6	0.7	1.3	0.4	-1.1
Leg fat mass (left)	0.6	2.5	2.9	-1.7	1.5
Bipolar Disorder (2011)	0.5	0.5	0.8	0.5	0.9
Body Mass Index (BMI) (2010)	0.5	0.7	1.3	-1.1	0.2
Allergy or Eczema	0.5	1.2	2.4	-1.6	0.0
Severe depression (siblings)	0.5	0.6	1.2	-1.1	-0.1
Trunk fat percentage	0.5	2.2	2.9	-1.7	1.2
Leg predicted mass (left)	0.5	2.8	3.8	-1.9	-1.3
Trunk fat mass	0.5	2.1	4.0	-2.0	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.4	-0.5	-1.2
Medication: Simvastatin	0.5	0.7	1.5	1.2	-0.2
Alcohol intake versus 10 years previously	0.5	0.7	1.2	0.4	1.1
Happiness	0.5	0.6	1.1	0.0	-1.1
Pulse wave reflection index	0.5	0.6	1.1	-1.1	0.2
Loud music exposure frequency	0.5	0.6	1.1	-1.0	-0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	-1.1	-0.0
Whole body fat mass	0.5	1.9	2.9	-1.7	0.9
Suffer from ‘nerves’	0.5	0.7	1.3	-0.4	1.1
Overall health rating	0.5	1.1	1.4	-1.0	1.2
Leg pain on walking	0.5	0.7	1.2	-1.1	0.4
Smoking status: Previous	0.5	0.7	1.1	-1.0	-0.5
Leg fat-free mass (right)	0.5	2.7	3.2	-1.8	-1.4
Ever had bowel cancer screening	0.5	0.6	1.2	-0.3	1.1
Qualifications: nursing, teaching	0.5	0.7	1.0	1.0	0.7
Medication for cholesterol	0.5	0.7	1.4	-0.3	-1.2
Medication: Gliclazide	0.5	0.5	0.8	0.9	-0.5
Leg predicted mass (right)	0.5	2.6	3.3	-1.8	-1.4
Arm fat mass (left)	0.5	2.0	3.2	-1.8	0.9
Average weekly champagne plus white wine intake	0.5	0.7	1.3	0.4	-1.1
Ever taken oral contraceptive pill	0.5	0.6	0.6	-0.8	-0.7
Number of operations (self-reported)	0.5	0.8	1.3	1.1	0.4
Intelligence (Savage-Jansen 2018)	0.4	1.2	1.6	0.9	1.3
Schizophrenia (2018)	0.4	0.9	1.5	-1.2	0.4
Schizophrenia vs Biploar Disorder	0.4	0.6	0.6	-0.7	0.8
Blood Red Count	0.4	3.4	6.6	-2.6	0.4
Pack years adult smoking proportion	0.4	0.6	0.6	0.8	0.7
Past tobacco smoking	0.4	0.7	0.7	0.8	0.8
Impedance of arm (right)	0.4	2.0	3.8	-0.3	-1.9
Hip circumference	0.4	1.9	2.9	-1.7	1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.6	1.3	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.8	-0.3	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	0.4	-0.9
Arm fat mass (right)	0.4	1.8	2.8	-1.7	0.9
Exposure to tobacco smoke at home	0.4	0.5	0.9	0.2	-0.9
Medication: Amlodipine	0.4	0.5	0.6	0.7	0.7
Birth weight	0.4	0.8	1.6	-0.3	-1.3
Emphysema/chronic bronchitis	0.4	0.5	0.5	0.7	0.7
Number of full sisters	0.4	0.5	0.6	0.8	0.5
Age at last live birth	0.4	0.5	1.0	1.0	0.2
Medication: Aspirin	0.4	0.5	1.0	1.0	0.0
Eye problems/disorders: Cataract	0.4	0.5	0.6	0.6	-0.8
Miserableness	0.4	0.8	1.0	1.0	0.7
Ever smoked	0.4	0.7	0.8	-0.7	-0.9
Age started oral contraceptive pill	0.4	0.5	1.0	-1.0	-0.0
Vascular/heart problems diagnosed by doctor	0.4	1.2	1.5	-1.2	-1.0
Alzheimer’s Disease (including proxy)	0.3	0.4	0.5	0.7	-0.6
Neuroticism (2016)	0.3	0.4	0.7	-0.4	0.8
Schizophrenia (2014)	0.3	0.6	0.9	-0.9	0.6
Fed-up feelings	0.3	0.6	0.6	0.8	0.8
Stomach or abdominal pain in last month	0.3	0.3	0.7	-0.1	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	-0.8	0.3
Waist circumference	0.3	1.3	1.9	-1.4	0.8
Hair/balding pattern: Pattern 2	0.3	0.4	0.4	0.6	-0.5
Heart attack	0.3	0.4	0.6	0.6	0.7
Fluid intelligence score	0.3	0.5	0.8	0.9	-0.5
Father’s age at death	0.3	0.4	0.7	-0.9	-0.2
Impedance of arm (left)	0.3	1.3	2.5	-0.1	-1.6
Tense / ‘highly strung’	0.3	0.4	0.6	-0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.7	-0.9	0.3
Medication: Blood pressure	0.3	0.4	0.5	0.7	0.6
Hypertension (Self-reported)	0.3	0.8	1.2	1.1	0.7
Long-standing illness, disability or infirmity	0.3	0.4	0.6	0.5	0.8
Friendships satisfaction	0.3	0.4	0.5	-0.7	0.5
Back pain experienced in last month	0.3	0.4	0.8	-0.9	-0.2
Asthma (self-reported)	0.3	0.5	1.0	-0.1	-1.0
Osteoporosis (self-reported)	0.3	0.4	0.7	0.8	-0.3
Medication: Aspirin	0.3	0.3	0.7	0.8	-0.0
Pack years of smoking	0.3	0.4	0.5	0.5	0.7
Impedance of whole body	0.3	1.4	2.3	-0.7	-1.5
Depressed Affect (Nagel 2018)	0.2	0.4	0.8	0.3	0.9
Ovarian Cancer	0.2	0.2	0.4	0.6	-0.2
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.4	-0.6	-0.3
Blood Eosinophil Count	0.2	1.3	1.9	-0.8	-1.4
Waist Hip Ratio (WHR)	0.2	1.0	1.8	0.4	-1.3
Lung FEV1/FVC ratio	0.2	1.0	1.7	0.6	1.3
Tanning	0.2	2.5	3.0	-1.4	-1.7
Vitamin and mineral supplements	0.2	0.3	0.4	-0.6	0.4
Impedance of leg (right)	0.2	0.8	1.4	-0.4	-1.2
Current tobacco smoking	0.2	0.4	0.7	0.9	-0.1
Relative age voice broke	0.2	0.3	0.5	0.7	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.0	-1.0	0.0
Impedance of leg (left)	0.2	0.8	1.5	-0.2	-1.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.3	-0.6	0.3
Allergy	0.2	0.5	1.0	1.0	-0.1
Worrier / anxious feelings	0.2	0.3	0.5	0.3	0.7
Hair/balding pattern: Pattern 4	0.2	0.5	0.9	-0.4	1.0
Peak expiratory flow (PEF)	0.2	0.5	1.0	0.0	-1.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	-0.4	-0.8
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	0.7	0.3
Age at first live birth	0.2	0.4	0.7	0.8	-0.3
Eye problems/disorders: None of the above	0.2	0.2	0.3	-0.4	-0.5
Medication: Allopurinol	0.2	0.2	0.4	0.6	0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.6	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.5	-0.1	0.7
Illnesses of father: Heart disease	0.2	0.3	0.4	-0.6	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.3	-0.4	-0.6
Medication: Bendroflumethiazide	0.2	0.3	0.4	-0.6	-0.4
Medication: Lisinopril	0.2	0.2	0.5	0.0	-0.7
Commuting to job workplace: Cycle	0.2	0.3	0.3	0.6	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	0.3	0.7
Pain experienced in last month	0.2	0.4	0.6	0.4	-0.8
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.6	0.3
Depression (Nagel 2018)	0.1	0.2	0.3	-0.6	-0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.5	0.3	0.7
Worry (Nagel 2018)	0.1	0.2	0.3	-0.5	0.3
Crohns Disease (2017)	0.1	0.1	0.2	0.4	0.2
Ulcerative Colitis (UC)	0.1	0.1	0.2	-0.0	-0.5
Major Depression (MDD)	0.1	0.1	0.1	-0.4	0.3
Reaction Time	0.1	0.1	0.2	-0.5	-0.1
Breast Cancer	0.1	0.3	0.3	0.5	0.6
Blood Platelet Count	0.1	0.6	1.3	-1.1	-0.2
Blood White Count	0.1	0.5	1.0	1.0	-0.1
Heel T-Score	0.1	1.1	2.2	0.2	1.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.4	0.6	-0.2
Neuroticism	0.1	0.3	0.6	-0.1	0.8
Hair Pigment	0.1	3.1	3.7	1.6	1.9
Number of treatments/medications taken	0.1	0.2	0.2	-0.3	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.4	-0.1	-0.6
Age when periods started (menarche)	0.1	0.2	0.3	0.3	-0.5
High blood pressure	0.1	0.3	0.5	0.7	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.4	-0.6	0.2
Supplements: Glucosamine	0.1	0.1	0.3	-0.5	-0.0
Number of incorrect matches in round	0.1	0.1	0.2	0.2	0.5
Nervous feelings	0.1	0.2	0.3	-0.4	0.5
Diabetes (self-reported)	0.1	0.1	0.1	0.3	-0.3
Pulse rate	0.1	0.2	0.3	0.3	-0.5
Asthma	0.1	0.2	0.5	0.1	-0.7
Prospective memory result	0.1	0.1	0.2	0.1	0.4
Worry too long after embarrassment	0.1	0.1	0.1	-0.3	-0.3
Wheeze or whistling in the chest in last year	0.1	0.3	0.4	-0.6	-0.3
Health satisfaction	0.1	0.1	0.2	-0.4	-0.1
Mean time to correctly identify matches	0.1	0.2	0.3	-0.6	0.1
Chest pain or discomfort	0.1	0.1	0.3	0.5	0.1
Supplements: Vitamin C	0.1	0.1	0.2	-0.1	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.4	0.2
Average weekly red wine intake	0.1	0.2	0.4	0.6	0.0
Diabetes diagnosed by doctor	0.1	0.1	0.3	0.5	0.0
Mineral and other dietary supplements	0.1	0.1	0.2	0.2	-0.5
Smoking status: Current	0.1	0.2	0.4	0.6	-0.2
Eye problems/disorders: Glaucoma	0.1	0.2	0.3	-0.6	-0.0
Medication: Blood pressure	0.1	0.2	0.3	-0.3	0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	-0.5	-0.0
Alcohol drinker status: Never	0.1	0.1	0.2	-0.5	-0.1
Irritability	0.1	0.1	0.2	-0.2	-0.4
Fractured/broken bones in last 5 years	0.1	0.2	0.3	-0.2	-0.5
Ever depressed for a whole week	0.1	0.1	0.2	0.4	-0.2
Irritable Bowel Disease (IBD)	0.0	0.0	0.0	0.1	-0.1
Mean Putamen Volume	0.0	0.0	0.0	-0.2	0.0
HDL Cholesterol	0.0	0.1	0.1	0.2	0.3
Hypothyroidism (self reported)	0.0	0.1	0.1	-0.4	0.0
Hearing difficulty/problems: Yes	0.0	0.1	0.1	-0.3	0.2
Medication: Levothyroxine sodium	0.0	0.0	0.1	-0.1	0.3
Hearing difficulty/problems with background noise	0.0	0.0	0.0	0.2	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.2	0.4
Pain all over the body in last month	0.0	0.0	0.0	0.2	-0.0
Neuroticism score	0.0	0.1	0.1	-0.4	0.2
Lung cancer (father)	0.0	0.0	0.0	-0.1	-0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	0.2	0.2
Comparative body size at age 10	0.0	0.0	0.0	0.1	0.0
Medication: Omeprazole	0.0	0.0	0.0	-0.1	0.1
Had major operations	0.0	0.0	0.0	0.1	-0.0
Mood swings	0.0	0.0	0.1	-0.1	0.3
Number of self-reported non-cancer illnesses	0.0	0.1	0.1	-0.2	0.3
Wears glasses or contact lenses	0.0	0.0	0.0	0.2	0.1
Financial situation satisfaction	0.0	0.0	0.0	0.1	-0.1
Myopia	0.0	0.1	0.1	0.4	0.0

Hub : Genes

R3HDM1

Models

Trait associations