Best TWAS P=6.36e-11 · Best GWAS P=8.91e-16 conditioned to 3.77e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-10C24.2 | 0.11 | 0.06 | lasso | 3 | 0.05 | 8.9e-05 | 8.0 | 6.5 | 7.3e-11 | 0.87 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Thyroid | CRTAP | 0.23 | 0.10 | enet | 26 | 0.16 | 1.9e-12 | -5.3 | -6.4 | 1.4e-10 | 0.10 | 0.99 | 0.00 | FALSE |
| 3 | GTEx | Thyroid | RP11-627J17.1 | 0.29 | 0.08 | enet | 22 | 0.11 | 5.0e-09 | -5.3 | -6.4 | 1.3e-10 | 0.09 | 0.97 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CRTAP | 0.02 | 0.01 | blup | 55 | 0.01 | 1.4e-03 | -5.7 | -5.8 | 5.4e-09 | 0.08 | 0.03 | 0.50 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GLB1 | 0.05 | 0.03 | blup | 83 | 0.03 | 2.3e-04 | -6.3 | 6.5 | 8.9e-11 | 0.00 | 0.00 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GLB1 | 0.03 | 0.00 | blup | 84 | 0.02 | 4.9e-03 | -4.3 | 6.5 | 6.4e-11 | 0.05 | 0.02 | 0.84 | TRUE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GLB1 | 0.06 | 0.02 | blup | 83 | 0.03 | 2.4e-03 | -4.3 | 5.4 | 7.8e-08 | 0.05 | 0.02 | 0.24 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | CRTAP | 0.07 | 0.03 | blup | 55 | 0.04 | 4.3e-05 | -6.8 | -6.3 | 2.9e-10 | 0.11 | 0.00 | 1.00 | FALSE |